Raymone Pajarillo

University of Pennsylvania

H指数:15

被引数:1,564

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Chimeric antigen receptor T cells against the IGHV4-34 B cell receptor specifically eliminate neoplastic and autoimmune B cells

针对IGHV4-34 b细胞受体的嵌合抗原受体T细胞特异性消除肿瘤性和自身免疫性b细胞

Science Translational Medicine

IF14.6

2026-02-040

PRE

Ivan J. Cohen; Audrey C. Bochi-Layec; Jean Lemoine; Scott Jenks; Pedram Bayat; Ki Hyun Kim; Huiwu Zhao; Ositadimma Ugwuanyi; Federico Stella; Guido Ghilardi; Giulia Gabrielli; Sarah McCuaig; Anastasia Iatrou; Elisavet Vlachonikola; Maria Karipidou; Eleni Bouziani; David Espie; Ranjani Ramasubramanian; Andreas Agathangelidis; Aditya Bhosale; Luca Paruzzo; Giovanni Medico; Bronte Kolar; Regina Bugrovsky; Puneeth Guruprasad; Li-Ping Wang; Jaryse Harris; Evgeny Arons; Yunlin Zhang; Raymone Pajarillo; Portia A. Kreiger; Chi-Ping Day; S. Cenk Sahinalp; Chih Hao Wu; Alessia Santi; Bria Fulmer; Marcos Cases; Matthew B. Palmer; Patrizia Porazzi; E. John Wherry; Robert J. Kreitman; Enrico Tiacci; Sokratis A. Apostolidis; Edward M. Behrens; Vijay Bhoj; Ignacio Sanz; Giorgio Inghirami; Stephen J. Schuster; Paolo Ghia; Kostas Stamatopoulos; Marco Ruella

Harnessing the CD2 axis to broaden and enhance the efficacy of CAR T cell therapies

Blood

IF23.1

2026-01-070

PRE

CD5 deletion enhances the antitumor activity of adoptive T cell therapies

CD5缺失增强过继性T细胞疗法的抗肿瘤活性

SCIENCE IMMUNOLOGY

IF16.3

2024-07-195

PRE

Patel, Ruchi P.; Ghilardi, Guido; Zhang, Yunlin; Chiang, Yi-Hao; Xie, Wei; Guruprasad, Puneeth; Kim, Ki Hyun; Chun, Inkook; Angelos, Mathew G.; Pajarillo, Raymone; Hong, Seok Jae; Lee, Yong Gu; Shestova, Olga; Shaw, Carolyn; Cohen, Ivan; Gupta, Aasha; Vu, Trang; Qian, Dean; Yang, Steven; Nimmagadda, Aditya; Snook, Adam E.; Siciliano, Nicholas; Rotolo, Antonia; Inamdar, Arati; Harris, Jaryse; Ugwuanyi, Ositadimma; Wang, Michael; Carturan, Alberto; Paruzzo, Luca; Chen, Linhui; Ballard, Hatcher J.; Blanchard, Tatiana; Xu, Chong; Abdel-Mohsen, Mohamed; Gabunia, Khatuna; Wysocka, Maria; Linette, Gerald P.; Carreno, Beatriz; Barrett, David M.; Teachey, David T.; Posey, Avery D.; Powell, Daniel J.; Sauter, C. Tor; Pileri, Stefano; Pillai, Vinodh; Scholler, John; Rook, Alain H.; Schuster, Stephen J.; Barta, Stefan K.; Porazzi, Patrizia; Ruella, Marco

Streamlined measurement of chimeric antigen receptor T-cell concentration, size, viability and two-color phenotyping during manufacturing

制造过程中嵌合抗原受体T细胞浓度，大小，活力和双色表型的简化测量

CYTOTHERAPY

IF3.2

2024-05-010

PRE

Efficacy and safety of bendamustine for lymphodepletion before lisocabtagene maraleucel

苯达莫司汀用于利索卡塔烯前淋巴细胞耗竭的疗效和安全性

JOURNAL OF HEMATOLOGY & ONCOLOGY

IF40.4

2024-04-220

OAAI

Immunologic Predictors of Vaccine Responsiveness in Patients With Lymphoma and Chronic Lymphocytic Leukemia

淋巴瘤和慢性淋巴细胞白血病患者疫苗反应性的免疫学预测指标

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2024-03-042

PRE

Chong, Elise A.; Kumashie, Kingsley Gideon; Chong, Emeline R.; Fabrizio, Joseph; Gupta, Aditi; Svoboda, Jakub; Barta, Stefan K.; Walsh, Kristy M.; Napier, Ellen B.; Lundberg, Rachel K.; Nasta, Sunita D.; Gerson, James N.; Landsburg, Daniel J.; Gonzalez, Joyce; Gaano, Andrew; Weirick, Madison E.; Mcallister, Christopher M.; Awofolaju, Moses; John, Gavin N.; Kammerman, Shane C.; Novacek, Josef; Pajarillo, Raymone; Lundgreen, Kendall A.; Tanenbaum, Nicole; Gouma, Sigrid; Drapeau, Elizabeth M.; Adamski, Sharon; D'Andrea, Kurt; Pattekar, Ajinkya; Hicks, Amanda; Korte, Scott; Sharma, Harsh; Herring, Sarah; Williams, Justine C.; Hamilton, Jacob T.; Bates, Paul; Hensley, Scott E.; Luning Prak, Eline T.; Greenplate, Allison R.; Wherry, E. John; Schuster, Stephen J.; Ruella, Marco; Vella, Laura A.

Bendamustine lymphodepletion before axicabtagene ciloleucel is safe and associates with reduced inflammatory cytokines

苯达莫司汀在axicabtagene ciloleucel之前进行淋巴细胞耗竭是安全的，并且与减少的炎症细胞因子有关

BLOOD ADVANCES

IF7.1

2024-01-268

OAAI

Ghilardi, Guido; Paruzzo, Luca; Svoboda, Jakub; Chong, Elise A.; Shestov, Alexander A.; Chen, Linhui; Cohen, Ivan J.; Gabrielli, Giulia; Nasta, Sunita D.; Porazzi, Patrizia; Landsburg, Daniel J.; Gerson, James N.; Carter, Jordan; Barta, Stefan K.; Yelton, Rebecca; Pajarillo, Raymone; Patel, Vrutti; White, Griffin; Ballard, Hatcher J.; Weber, Elizabeth; Napier, Ellen; Chong, Emeline R.; Fraietta, Joseph A.; Garfall, Alfred L.; Porter, David L.; Milone, Michael C.; O'Connor, Roderick; Schuster, Stephen J.; Ruella, Marco

T cell lymphoma and secondary primary malignancy risk after commercial CAR T cell therapy

商业CAR T细胞治疗后T细胞淋巴瘤和继发性原发性恶性肿瘤风险

NATURE MEDICINE

IF50

2024-01-2481

PRE

Ghilardi, Guido; Fraietta, Joseph A.; Gerson, James N.; Van Deerlin, Vivianna M.; Morrissette, Jennifer J. D.; Caponetti, Gabriel C.; Paruzzo, Luca; Harris, Jaryse C.; Chong, Elise A.; Adaniya, Sandra P. Susanibar; Svoboda, Jakub; Nasta, Sunita D.; Ugwuanyi, Ositadimma H.; Landsburg, Daniel J.; Fardella, Eugenio; Waxman, Adam J.; Chong, Emeline R.; Patel, Vrutti; Pajarillo, Raymone; Kulikovskaya, Irina; Lieberman, David B.; Cohen, Adam D.; Levine, Bruce L.; Stadtmauer, Edward A.; Frey, Noelle V.; Vogl, Dan T.; Hexner, Elizabeth O.; Barta, Stefan K.; Porter, David L.; Garfall, Alfred L.; Schuster, Stephen J.; June, Carl H.; Ruella, Marco

Safety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with fast on- and off-rates against non-Hodgkin lymphoma: a first-in-human study

靶向CD19近膜域的新型anti-CD19嵌合抗原受体T细胞产品对非霍奇金淋巴瘤的安全性和有效性: 一项首次人体研究

MOLECULAR CANCER

IF33.9

2023-12-098

OAAI

Zhang, Yunlin; Patel, Ruchi P.; Kim, Ki Hyun; Cho, Hyungwoo; Jo, Jae-Cheol; Jeong, Seong Hyun; Oh, Sung Yong; Choi, Yoon Seok; Kim, Sung Hyun; Lee, Ji Hyun; Angelos, Mathew; Guruprasad, Puneeth; Cohen, Ivan; Ugwuanyi, Ositadimma; Lee, Yong Gu; Pajarillo, Raymone; Cho, Jong Hyun; Carturan, Alberto; Paruzzo, Luca; Ghilardi, Guido; Wang, Michael; Kim, Soohwan; Kim, Sung-Min; Lee, Hyun-Jong; Park, Ji-Ho; Cui, Leiguang; Lee, Tae Bum; Hwang, In-Sik; Lee, Young-Ha; Lee, Yong-Jun; Porazzi, Patrizia; Liu, Dongfang; Lee, Yoon; Kim, Jong-Hoon; Lee, Jong-Seo; Yoon, Dok Hyun; Chung, Junho; Ruella, Marco

Apoptosis: a Janus bifrons in T-cell immunotherapy

细胞凋亡: T细胞免疫治疗中的Janus bifrons

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2023-04-1311

OAAI

Modulation of the gut microbiota engages antigen cross-presentation to enhance antitumor effects of CAR T cell immunotherapy

调节肠道菌群参与抗原交叉呈递以增强CAR T细胞免疫疗法的抗肿瘤作用

MOLECULAR THERAPY

IF12

2023-03-0120

OAAI

Uribe-Herranz, Mireia; Beghi, Silvia; Ruella, Marco; Parvathaneni, Kalpana; Salaris, Silvano; Kostopoulos, Nektarios; George, Subin S.; Pierini, Stefano; Krimitza, Elisavet; Costabile, Francesca; Ghilardi, Guido; Amelsberg, Kimberly, V; Lee, Yong Gu; Pajarillo, Raymone; Markmann, Caroline; McGettigan-Croce, Bevin; Agarwal, Divyansh; Frey, Noelle; Lacey, Simon F.; Scholler, John; Gabunia, Khatuna; Wu, Gary; Chong, Elise; Porter, David L.; June, Carl H.; Schuster, Stephen J.; Bhoj, Vijaj; Facciabene, Andrea

Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy (March, 10.1038/s41591-022-01702-9, 2022)

NATURE MEDICINE

IF50

2022-10-173

Smith, Melody; Dai, Anqi; Ghilardi, Guido; Amelsberg, Kimberly V.; Devlin, Sean M.; Pajarillo, Raymone; Slingerland, John B.; Beghi, Silvia; Herrera, Pamela S.; Giardina, Paul; Clurman, Annelie; Dwomoh, Emmanuel; Armijo, Gabriel; Gomes, Antonio L. C.; Littmann, Eric R.; Schluter, Jonas; Fontana, Emily; Taur, Ying; Park, Jae H.; Palomba, Maria Lia; Halton, Elizabeth; Ruiz, Josel; Jain, Tania; Pennisi, Martina; Afuye, Aishat Olaide; Perales, Miguel-Angel; Freyer, Craig W.; Garfall, Alfred; Gier, Shannon; Nasta, Sunita; Landsburg, Daniel; Gerson, James; Svoboda, Jakub; Cross, Justin; Chong, Elise A.; Giralt, Sergio; Gill, Saar I.; Riviere, Isabelle; Porter, David L.; Schuster, Stephen J.; Sadelain, Michel; Frey, Noelle; Brentjens, Renier J.; June, Carl H.; Pamer, Eric G.; Peled, Jonathan U.; Facciabene, Andrea; van den Brink, Marcel R. M.; Ruella, Marco

Bendamustine is safe and effective for lymphodepletion before tisagenlecleucel in patients with refractory or relapsed large B-cell lymphomas

ANNALS OF ONCOLOGY

IF65.4

2022-09-0147

OAAI

Modulation of BCL-2 in Both T Cells and Tumor Cells to Enhance Chimeric Antigen Receptor T-cell Immunotherapy against Cancer

CANCER DISCOVERY

IF33.3

2022-07-2944

Lee, Yong Gu; Guruprasad, Puneeth; Ghilardi, Guido; Pajarillo, Raymone; Sauter, Christopher Tor; Patel, Ruchi; Ballard, Hatcher J.; Hong, Seok Jae; Chun, Inkook; Yang, Nicholas; V. Amelsberg, Kimberly; Cummins, Katherine D.; Svoboda, Jakub; Gill, Saar; Chong, Elise A.; North, Khrystyna; Church, Sarah E.; Fraietta, Joseph A.; Chang, Wan -Jung; Lacey, Simon F.; Lu, Xueqing Maggie; Zhang, Yunlin; Whig, Kanupriya; Schultz, David C.; Cherry, Sara; Gerson, Jame; Schuster, Stephen J.; Porazzi, Patrizia; Ruella, Marco

Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy

肠道微生物组与anti-CD19 CAR T细胞治疗后的反应和毒性相关

NATURE MEDICINE

IF50

2022-03-14158

Smith, Melody; Dai, Anqi; Ghilardi, Guido; Amelsberg, Kimberly, V; Devlin, Sean M.; Pajarillo, Raymone; Slingerland, John B.; Beghi, Silvia; Herrera, Pamela S.; Giardina, Paul; Clurman, Annelie; Dwomoh, Emmanuel; Armijo, Gabriel; Gomes, Antonio L. C.; Littmann, Eric R.; Schluter, Jonas; Fontana, Emily; Taur, Ying; Park, Jae H.; Palomba, Maria Lia; Halton, Elizabeth; Ruiz, Josel; Jain, Tania; Pennisi, Martina; Afuye, Aishat Olaide; Perales, Miguel-Angel; Freyer, Craig W.; Garfall, Alfred; Gier, Shannon; Nasta, Sunita; Landsburg, Daniel; Gerson, James; Svoboda, Jakub; Cross, Justin; Chong, Elise A.; Giralt, Sergio; Gill, Saar, I; Riviere, Isabelle; Porter, David L.; Schuster, Stephen J.; Sadelain, Michel; Frey, Noelle; Brentjens, Renier J.; June, Carl H.; Pamer, Eric G.; Peled, Jonathan U.; Facciabene, Andrea; van den Brink, Marcel R. M.; Ruella, Marco

Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells

NATURE MEDICINE

IF50

2021-04-22112

Singh, Nathan; Frey, Noelle, V; Engels, Boris; Barrett, David M.; Shestova, Olga; Ravikumar, Pranali; Cummins, Katherine D.; Lee, Yong Gu; Pajarillo, Raymone; Chun, Inkook; Shyu, Amy; Highfill, Steven L.; Price, Andrew; Zhao, Linlin; Peng, Liaomin; Granda, Brian; Ramones, Melissa; Lu, Xueqing Maggie; Christian, David A.; Perazzelli, Jessica; Lacey, Simon F.; Roy, Nathan H.; Burkhardt, Janis K.; Colomb, Florent; Damra, Mohammad; Abdel-Mohsen, Mohamed; Liu, Ting; Liu, Dongfang; Standley, Daron M.; Young, Regina M.; Brogdon, Jennifer L.; Grupp, Stephan A.; June, Carl H.; Maude, Shannon L.; Gill, Saar; Ruella, Marco

Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction

白血病死亡受体信号受损通过诱导CAR T细胞功能障碍导致抗原非依赖性耐药

Cancer Discovery

IF33.3

2020-04-01206

OAAI

Raymone Pajarillo

个人简介

教育背景

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