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Translational molecular imaging and drug development in sclerosis 多发性硬化症的分子影像学与药物开发 Tay, Daniel; Ahmed, Hazem; Dawoud, Alyaa; Salam, Mohamed; Gobbi, Luca; Grether, Uwe; Edelmann, Martin R.; Wittwer, Matthias B.; Collin, Ludovic; Atz, Kenneth; Keaney, James; Giroud, Maude; Rossi, Alexia; Gennari, Antonio Giulio; Pagano, Gennaro; Parrot, Neil John; Barakovic, Muhamed; Rominger, Axel; Gebhard, Catherine; Ametamey, Simon M.; Saindane, Amit M.; Liang, Steven H.; Haider, Achi 分享 收藏
Cerebrospinal Fluid Biomarkers of NLRP3 Pathway, Immune Dysregulation, and Neurodegeneration in Parkinson's Disease: A Meta-Analysis NLRP3通路、免疫失调和神经退行性变在帕金森病中的脑脊液生物标志物：一项meta分析 Marinescu, Alina-mariuca; Machado, Venissa; Pagano, Gennaro; Muelhardt, Nicoletta Milani; Kustermann, Thomas; Mracsko, Eva Zsuzsanna; Brockmann, Kathrin; Shariati, Nima; Anzures-Cabrera, Judith; Zinnhardt, Bastian 分享 收藏
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A Phase 2b, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of intravenous prasinezumab in early-stage Parkinson's disease (PADOVA): Rationale, design, and baseline data Nikolcheva, Tania; Pagano, Gennaro; Pross, Nathalie; Simuni, Tanya; Marek, Kenneth; Postuma, Ronald B.; Pavese, Nicola; Stocchi, Fabrizio; Seppi, Klaus; Monnet, Annabelle; Shariati, Nima; Ricci, Benedicte; Rutten-Jacobs, Loes; Respondek, Gesine; Kustermann, Thomas; Taylor, Kirsten I.; Trundell, Dylan; Fontoura, Paulo; Doody, Rachelle; Svoboda, Hanno; Bonni, Azad; Prasinezumab Study Grp 分享 收藏
Estimation of and clinical consensus on the meaningful motor progression threshold on MDS-UPDRS Part III Trundell, Dylan; Davies, Evan W.; Barrett, Louise; Zanigni, Stefano; Shariati, Nima; Rogers, Rebecca; Monnet, Annabelle; Moore, Emma; Pross, Nathalie; Pagano, Gennaro; Cano, Stefan; Nikolcheva, Tania 分享 收藏
Biologically defined neuronal synuclein disease as a tool to advance drug development Pagano, Gennaro; Dam, Tien; Kerchner, Geoffrey A.; Galpern, Wendy R.; Biagioni, Milton; Karan, Rajesh; Jennings, Danna; Peterschmitt, M. Judith; Nikolcheva, Tania; Brundin, Patrik 分享 收藏
Accelerating Parkinson's Disease drug development with federated learning approaches Khanna, Amit; Adams, Jamie; Antoniades, Chrystalina; Bloem, Bastiaan R.; Carroll, Camille; Cedarbaum, Jesse; Cosman, Joshua; Dexter, David T.; Dockendorf, Marissa F.; Edgerton, Jeremy; Gaetano, Laura; Goikoetxea, Erkuden; Hill, Derek; Horak, Fay; Izmailova, Elena S.; Kangarloo, Tairmae; Katabi, Dina; Kopil, Catherine; Lindemann, Michael; Mammen, Jennifer; Marek, Kenneth; Mcfarthing, Kevin; Mirelman, Anat; Muller, Martijn; Pagano, Gennaro; Peterschmitt, M. Judith; Ren, Jie; Rochester, Lynn; Sardar, Sakshi; Siderowf, Andrew; Simuni, Tanya; Stephenson, Diane; Swanson-Fischer, Christine; Wagner, John A.; Jones, Graham B. 分享 收藏
Sustained effect of prasinezumab on Parkinson's disease motor progression in the open-label extension of the PASADENA trial Pagano, Gennaro; Monnet, Annabelle; Reyes, Adriana; Ribba, Benjamin; Svoboda, Hanno; Kustermann, Thomas; Simuni, Tanya; Postuma, Ronald B.; Pavese, Nicola; Stocchi, Fabrizio; Brockmann, Kathrin; Smigorski, Krzysztof; Gerbaldo, Valentina; Fontoura, Paulo; Doody, Rachelle; Kerchner, Geoffrey A.; Brundin, Patrik; Marek, Kenneth; Bonni, Azad; Nikolcheva, Tania 分享 收藏
Neuronal alpha-Synuclein Disease integrated staging system performance in PPMI, PASADENA, and SPARK baseline cohorts PPMI，帕萨迪纳和SPARK基线队列中的神经元 α-突触核蛋白疾病综合分期系统性能 Dam, Tien; Pagano, Gennaro; Brumm, Michael C.; Gochanour, Caroline; Poston, Kathleen L.; Weintraub, Daniel; Chahine, Lana M.; Coffey, Christopher; Tanner, Caroline M.; Kopil, Catherine M.; Xiao, Yuge; Chowdhury, Sohini; Concha-Marambio, Luis; Dibiaso, Peter; Foroud, Tatiana; Frasier, Mark; Jennings, Danna; Kieburtz, Karl; Merchant, Kalpana; Mollenhauer, Brit; Montine, Thomas J.; Nudelman, Kelly; Seibyl, John; Sherer, Todd; Singleton, Andrew; Stephenson, Diane; Stern, Matthew; Soto, Claudio; Tolosa, Eduardo; Siderowf, Andrew; Dunn, Billy; Simuni, Tanya; Marek, Kenneth; Parkinsons Progression Markers Initiative, Caroline 分享 收藏
Modeling of Parkinson's Disease Progression and Implications for Detection of Disease Modification in Treatment Trials Ribba, Benjamin; Simuni, Tanya; Marek, Kenneth; Siderowf, Andrew; Diack, Cheikh; Pierrillas, Philippe Bernard; Monnet, Annabelle; Ricci, Benedicte; Nikolcheva, Tania; Pagano, Gennaro 分享 收藏
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Prasinezumab slows motor progression in rapidly progressing early-stage Parkinson's disease Pagano, Gennaro; Taylor, Kirsten I.; Cabrera, Judith Anzures; Simuni, Tanya; Marek, Kenneth; Postuma, Ronald B.; Pavese, Nicola; Stocchi, Fabrizio; Brockmann, Kathrin; Svoboda, Hanno; Trundell, Dylan; Monnet, Annabelle; Doody, Rachelle; Fontoura, Paulo; Kerchner, Geoffrey A.; Brundin, Patrik; Nikolcheva, Tania; Bonni, Azad 分享 收藏
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Phase Ib Study Design Evaluating The Safety, Pharmacokinetics And Pharmacodynamics Of Selnoflast, A Novel NLRP3 Inflammasome Inhibitor In Early-Stage PD D'Urso, Giulia; Thomann, Alessandra; Anzures-Cabrera, Judith; Zinnhardt, Bastian; Ricci, Benedicte; Bailey, Lorna; Smigorski, Krzysztof; Machado, Venissa; Mracsko, Eva Zsuszsanna; Pavese, Nicola; Marek, Kenneth; Brockmann, Kathrin; Simuni, Tanya; Muelhardt, Nicoletta Milan; Pagano, Gennaro 分享 收藏
Exploratory Delayed-Start Analysis Of PASADENA Part 3 52-Week OLE Evaluating Prasinezumab Efficacy On Motor Progression And Complications In Early-Stage PD Pagano, Gennaro; Zanigni, Stefano; Monnet, Annabelle; Taylor, Kirsten; Hahn, Andrea; Simuni, Tanya; Marek, Kenneth; Postuma, Ronald; Pavese, Nicola; Stocchi, Fabrizio; Svoboda, Hanno; Fontoura, Paulo; Doody, Rachelle; Kerchner, Geoffrey; Bonni, Azad; Nikolcheva, Tania 分享 收藏
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