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Immunothrombolytic monocyte-neutrophil axes dominate the single-cell landscape of human thrombosis and correlate with thrombus resolution 免疫溶栓单核细胞-中性粒细胞轴主导人类血栓形成的单细胞景观，并与血栓溶解相关。 Pekayvaz, Kami; Kilani, Badr; Joppich, Markus; Eivers, Luke; Brambs, Sophia; Knottenberg, Viktoria; Akgol, Sezer; Yue, Keyang; Li, Lukas; Martinez-Navarro, Alejandro; Kaiser, Rainer; Meissner, Nina; Schulz, Heiko; Belz, Larissa; Akhalkatsi, Anastassia; Stockhausen, Sven; Mueller, Tonina T.; Millonig, Simon; Hartelt, Lea; Gold, Christoph; Janjic, Aleksandar; Polewka, Vivien; Wendler, Franziska; zu Senden, Augustin Droste; Titova, Anna; Leunig, Alexander; Voelkl, Michael; Engelmann, Bernd; Petzsche, Moritz R. Hernandez; Boeckh-Behrens, Tobias; Liebig, Thomas; Winning, Sandra; Fandrey, Joachim; Dichgans, Martin; Enard, Wolfgang; Zimmer, Ralf; Tiedt, Steffen; Massberg, Steffen; Nicolai, Leo; Stark, Konstantin 分享 收藏
Targeting CDC42 reduces skeletal degeneration after hematopoietic stem cell transplantation Landspersky, Theresa; Stein, Merle; Sacma, Mehmet; Geuder, Johanna; Braitsch, Krischan; Riviere, Jennifer; Hettler, Franziska; Marquez, Sandra Romero; Vilne, Baiba; Hameister, Erik; Richter, Daniel; Schoenhals, Emely; Tuckermann, Jan; Verbeek, Mareike; Herhaus, Peter; Hecker, Judith S.; Bassermann, Florian; Goetze, Katharina S.; Enard, Wolfgang; Geiger, Hartmut; Oostendorp, Robert A. J.; Schreck, Christina 分享 收藏
Evidence for compensatory evolution within pleiotropic regulatory elements Kliesmete, Zane; Orchard, Peter; Lee, Victor Yan Kin; Geuder, Johanna; Krauss, Simon M.; Ohnuki, Mari; Jocher, Jessica; Vieth, Beate; Enard, Wolfgang; Hellmann, Ines 分享 收藏
Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes Pekayvaz, Kami; Losert, Corinna; Knottenberg, Viktoria; Gold, Christoph; van Blokland, Irene V.; Oelen, Roy; Groot, Hilde E.; Benjamins, Jan Walter; Brambs, Sophia; Kaiser, Rainer; Gottschlich, Adrian; Hoffmann, Gordon Victor; Eivers, Luke; Martinez-Navarro, Alejandro; Bruns, Nils; Stiller, Susanne; Akgoel, Sezer; Yue, Keyang; Polewka, Vivien; Escaig, Raphael; Joppich, Markus; Janjic, Aleksandar; Popp, Oliver; Kobold, Sebastian; Petzold, Tobias; Zimmer, Ralf; Enard, Wolfgang; Saar, Kathrin; Mertins, Philipp; Huebner, Norbert; van der Harst, Pim; Franke, Lude H.; van der Wijst, Monique G. P.; Massberg, Steffen; Heinig, Matthias; Nicolai, Leo; Stark, Konstantin 分享 收藏
Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdle Sonsalla, Giovanna; Malpartida, Ana Belen; Riedemann, Therese; Gusic, Mirjana; Rusha, Ejona; Bulli, Giorgia; Najas, Sonia; Janjic, Aleks; Hersbach, Bob A.; Smialowski, Pawel; Drukker, Micha; Enard, Wolfgang; Prehn, Jochen H. M.; Prokisch, Holger; Goetz, Magdalena; Masserdotti, Giacomo 分享 收藏
Peripheral priming induces plastic transcriptomic and proteomic responses in circulating neutrophils required for pathogen containment Kaiser, Rainer; Gold, Christoph; Joppich, Markus; Loew, Quentin; Akhalkatsi, Anastassia; Mueller, Tonina T.; Offensperger, Felix; zu Senden, Augustin Droste; Popp, Oliver; di Fina, Lea; Knottenberg, Viktoria; Martinez-Navarro, Alejandro; Eivers, Luke; Anjum, Afra; Escaig, Raphael; Bruns, Nils; Briem, Eva; Dewender, Robin; Muraly, Abhinaya; Akgoel, Sezer; Ferraro, Bartolo; Hoeflinger, Jonathan K. L.; Polewka, Vivien; Khaled, Najib Ben; Allgeier, Julian; Tiedt, Steffen; Dichgans, Martin; Engelmann, Bernd; Enard, Wolfgang; Mertins, Philipp; Hubner, Norbert; Weckbach, Ludwig; Zimmer, Ralf; Massberg, Steffen; Stark, Konstantin; Nicolai, Leo; Pekayvaz, Kami 分享 收藏
Targeting a cell-specific microRNA repressor of CXCR4 ameliorates atherosclerosis in mice Cimen, Ismail; Natarelli, Lucia; Kichi, Zahra Abedi; Henderson, James M.; Farina, Floriana M.; Briem, Eva; Aslani, Maria; Megens, Remco T. A.; Jansen, Yvonne; Mann-Fallenbuchel, Elizabeth; Gencer, Selin; Duchene, Johan; Nazari-Jahantigh, Maliheh; van der Vorst, Emiel P. C.; Enard, Wolfgang; Doering, Yvonne; Schober, Andreas; Santovito, Donato; Weber, Christian 分享 收藏
CSF3R T618I Collaborates With RUNX1-RUNX1T1 to Expand Hematopoietic Progenitors and Sensitizes to GLI Inhibition Swoboda, Anja S.; Arfelli, Vanessa C.; Danese, Anna; Windisch, Roland; Kerbs, Paul; Monte, Enric Redondo; Bagnoli, Johannes W.; Chen-Wichmann, Linping; Caroleo, Alessandra; Cusan, Monica; Krebs, Stefan; Blum, Helmut; Sterr, Michael; Enard, Wolfgang; Herold, Tobias; Colome-Tatche, Maria; Wichmann, Christian; Greif, Philipp A. 分享 收藏
Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation Pekayvaz, Kami; Gold, Christoph; Hoseinpour, Parandis; Engel, Anouk; Martinez-Navarro, Alejandro; Eivers, Luke; Coletti, Raffaele; Joppich, Markus; Dionisio, Flavio; Kaiser, Rainer; Tomas, Lukas; Janjic, Aleksandar; Knott, Maximilian; Mehari, Fitsumbirhan; Polewka, Vivien; Kirschner, Megan; Boda, Annegret; Nicolai, Leo; Schulz, Heiko; Titova, Anna; Kilani, Badr; Lorenz, Michael; Fingerle-Rowson, Gunter; Bucala, Richard; Enard, Wolfgang; Zimmer, Ralf; Weber, Christian; Libby, Peter; Schulz, Christian; Massberg, Steffen; Stark, Konstantin 分享 收藏
The effect of background noise and its removal on the analysis of single-cell expression data Janssen, Philipp; Kliesmete, Zane; Vieth, Beate; Adiconis, Xian; Simmons, Sean; Marshall, Jamie; McCabe, Cristin; Heyn, Holger; Levin, Joshua Z.; Enard, Wolfgang; Hellmann, Ines 分享 收藏
Wound infiltrating adipocytes are not myofibroblasts Gopal, Shruthi Kalgudde; Dai, Ruoxuan; Stefanska, Ania Maria; Ansari, Meshal; Zhao, Jiakuan; Ramesh, Pushkar; Bagnoli, Johannes W.; Correa-Gallegos, Donovan; Lin, Yue; Christ, Simon; Angelidis, Ilias; Lupperger, Valerio; Marr, Carsten; Davies, Lindsay C.; Enard, Wolfgang; Machens, Hans-Guenther; Schiller, Herbert B.; Jiang, Dongsheng; Rinkevich, Yuval 分享 收藏
UHMK1 is a novel splicing regulatory kinase Arfelli, Vanessa C.; Chang, Yun-Chien; Bagnoli, Johannes W.; Kerbs, Paul; Ciamponi, Felipe E.; Paz, Laissa M. da S.; Pankivskyi, Serhii; Salone, Jean de Matha; Maucuer, Alexandre; Massirer, Katlin B.; Enard, Wolfgang; Kuster, Bernhard; Greif, Philipp A.; Archangelo, Leticia Froehlich 分享 收藏
Regulatory and coding sequences of TRNP1 co-evolve with brain size and cortical folding in mammals Kliesmete, Zane; Wange, Lucas Esteban; Vieth, Beate; Esgleas, Miriam; Radmer, Jessica; Huelsmann, Matthias; Geuder, Johanna; Richter, Daniel; Ohnuki, Mari; Goetz, Magdelena; Hellmann, Ines; Enard, Wolfgang 分享 收藏
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GPR55 in B cells limits atherosclerosis development and regulates plasma cell maturation Guillamat-Prats, Raquel; Hering, Daniel; Derle, Abhishek; Rami, Martina; Haerdtner, Carmen; Santovito, Donato; Rinne, Petteri; Bindila, Laura; Hristov, Michael; Pagano, Sabrina; Vuilleumier, Nicolas; Schmid, Sofie; Janjic, Aleksandar; Enard, Wolfgang; Weber, Christian; Maegdefessel, Lars; Faussner, Alexander; Hilgendorf, Ingo; Steffens, Sabine 分享 收藏
In vivo PDX CRISPR/Cas9 screens reveal mutual therapeutic targets to overcome heterogeneous acquired chemo-resistance Wirth, Anna-Katharina; Wange, Lucas; Vosberg, Sebastian; Henrich, Kai-Oliver; Rausch, Christian; Oezdemir, Erbey; Zeller, Christina M.; Richter, Daniel; Feuchtinger, Tobias; Kaller, Markus; Hermeking, Heiko; Greif, Philipp A.; Senft, Daniela; Jurinovic, Vindi; Bahrami, Ehsan; Jayavelu, Ashok Kumar; Westermann, Frank; Mann, Matthias; Enard, Wolfgang; Herold, Tobias; Jeremias, Irmela 分享 收藏
TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation Stolz, Paul; Mantero, Angelo Salazar; Tvardovskiy, Andrey; Ugur, Enes; Wange, Lucas E.; Mulholland, Christopher B.; Cheng, Yuying; Wierer, Michael; Enard, Wolfgang; Schneider, Robert; Bartke, Till; Leonhardt, Heinrich; Elsasser, Simon J.; Bultmann, Sebastian 分享 收藏
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