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D

Dieter Henrik Heiland

medical center

40H指数
307论文数
9.1K被引数
收录论文 117
发表时间
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Core2Edge: a human glioblastoma organoid–brain slice model capturing infiltration and transcriptional heterogeneity from core to single-cell dispersionCore2Edge：一种捕获从核心到单细胞分散的浸润和转录异质性的人类胶质母细胞瘤类器官-脑片模型
errNature Protocols
IF16
err2026-07-28
err0
PREAI
errAhmad Melhem; Barbara E. F. Pregler; Juan Eduardo Rodriguez-Gatica; Lea L. Friker; Jake Thomas; Marieta I. Toma; Mike-Andrew Westhoff; Vidhya M. Ravi; Valeri Borger; Dieter Henrik Heiland; Julian P. Layer; Andreas Schlitzer; Torsten Pietsch; Michael Hölzel; Andreas Waha; Hartmut Vatter; Martin K. Schwarz; Ulrich Herrlinger; Ulrich Kubitscheck; Anna-Laura Potthoff; Matthias Schneider
err分享
err收藏
Glioma-intrinsic MAPK/ERK signaling promotes immunotherapy efficacy through T cell infiltration and interferon responses胶质瘤-内在MAPK/ERK信号通过T细胞浸润和干扰素反应促进免疫治疗效果
errNature Communications
IF15.7
err2026-06-25
err0
errOAAI
errKwang-Soo Kim; Junyi Zhang; Víctor A. Arrieta; Crismita Dmello; Elena Grabis; Yahaya A. Yabo; Si Wang; Karl Habashy; Joseph Duffy; Junfei Zhao; Andrew Gould; Rishi Jain; Li Chen; Jian Hu; Irina Balyasnikova; Dhan Chand; Daniel Levey; Peter Canoll; Wenting Zhao; Peter A. Sims; Raul Rabadan; Surya Pandey; Bin Zhang; Pouya Jamshidi; Catalina Lee-Chang; Dieter Henrik Heiland; Adam M. Sonabend
err分享
err收藏
Long-term endocrine trajectories and reoperation risk after surgery for Rathke’s cleft cysts: a single-center cohort study of 177 patientsRathke裂孔囊肿术后长期内分泌变化轨迹及再手术风险：一项包含177例患者的单中心队列研究
errPituitary
IF3.4
err2026-05-18
err0
errOAAI
errNatalia Kremenevski; Waseem Masalha; Daniel Delev; Roland Coras; Arnd Doerfler; Dieter Henrik Heiland; Oliver Schnell
err分享
err收藏
A microenvironment-determined risk continuum refines subtyping in meningioma and reveals determinants of machine learning-based tumor classification微环境确定的风险连续体可改善脑膜瘤的亚型，并揭示基于机器学习的肿瘤分类的决定因素
errNature Genetics
IF29
err2026-02-09
err0
errOAAI
errSybren L. N. Maas; Yiheng Tang; Eric Stutheit-Zhao; Ramin Rahmanzade; Christina Blume; Thomas Hielscher; Ferdinand Zettl; Salvatore Benfatto; Domenico Calafato; Martin Sill; Jasim Kada Benotmane; Yahaya A. Yabo; Felix Behling; Abigail Suwala; Helin Kardo; Michael Ritter; Matthieu Peyre; Roman Sankowski; Konstantin Okonechnikov; Philipp Sievers; Areeba Patel; David Reuss; Mirco J. Friedrich; Damian Stichel; Daniel Schrimpf; Thierry P. P. Van den Bosch; Katja Beck; Hans-Georg Wirsching; Gerhard Jungwirth; C. Oliver Hanemann; Katrin Lamszus; Nima Etminan; Andreas Unterberg; Christian Mawrin; Marc Remke; Olivier Ayrault; Peter Lichter; Guido Reifenberger; Michael Platten; Tim Kacprowski; Markus List; Josch K. Pauling; Jan Baumbach; Till Milde; Rachel Grossmann; Zvi Ram; Miriam Ratliff; Jan-Philipp Mallm; Marian C. Neidert; Eelke M. Bos; Marco Prinz; Michael Weller; Till Acker; Felix J. Hartmann; Matthias Preusser; Ghazaleh Tabatabai; Christel Herold-Mende; Sandro M. Krieg; David T. W. Jones; Stefan M. Pfister; Wolfgang Wick; Michel Kalamarides; Andreas von Deimling; Dieter Henrik Heiland; Volker Hovestadt; Moritz Gerstung; Matthias Schlesner; Felix Sahm
err分享
err收藏
A Chemotherapy-Evoked Microglial Circuit Fuels Invasion in Glioblastoma via S1P-ROCK Signaling化疗诱导的小胶质细胞回路通过S1P-ROCK信号通路促进胶质母细胞瘤侵袭
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errChoja, Rafal K.; Grabis, Elena; Kazi, Hasaan A.; O'shea, Maeve C.; Falkowski, Victoria; Faisal, Umme H.; Olson, Ian E. Olson; Turunen, Jillyn R.; Koutah, Lara Koutah; Kham, Sana A.; Lazanyi, Irene; Chen, Rebecca X.; Miska, Jason M.; Heiland, Dieter H.; Ahmed, Atique
err分享
err收藏
DEEP LEARNING ANALYSIS OF SPATIALLY RESOLVED SINGLE-CELL TRANSCRIPTOMICS UNCOVERS CELLULAR REORGANIZATION IN GLIOBLASTOMA AT RECURRENCE基于空间分辨的单细胞转录组学的深度学习分析揭示了复发胶质母细胞瘤中的细胞重排
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errYabo, Y. A.; Grabis, E.; Peng, T.; Benotmane, J. K.; Kueckelhaus, J.; Zhang, J.; Villa, G.; Neidert, N.; Prinz, M.; Beck, J.; Ahmed, A.; Schnell, O.; Sahm, F.; Venkataramani, V.; Ricklefs, F. L.; Sankowski, R.; Heiland, D.
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err收藏
MODELING GLIOBLASTOMA TREATMENT RESPONSES: INSIGHTS INTO TUMOR PLASTICITY AND THE ROLE OF THE TUMOR MICROENVIRONMENT胶质母细胞瘤治疗反应的建模：肿瘤可塑性和肿瘤微环境作用的洞见
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errSanz, M. de Lucas; Allahverdi, H.; Nosirov, B.; Sanchez, P. Moreno; Milan, M. Baroni; Lipsa, A.; Rezaeipour, M.; Dording, C.; Brown, D.; Langlands, J. M.; Grzyb, K.; Yabo, Y. A.; Zhang, J.; Heiland, D. H.; Michelucci, A.; Nazarov, P., V; Golebiewska, A.
err分享
err收藏
GLIOSARCOMA SPATIAL ARCHITECTURE IS DEFINED BY UNIQUE ECM AND IMMUNE REMODELING TRANSCRIPTIONAL PROFILES胶质肉瘤的空间结构由独特的ECM和免疫重塑转录谱定义。
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errMuhlbauer, M.; Neidert, N.; Beck, J.; Schnell, O.; Sahm, F.; Heiland, D.
err分享
err收藏
P01.24.B CORE2EDGE: A HUMAN GLIOBLASTOMA ORGANOID AND BRAIN SLICE CO-CULTURE MODEL CAPTURING TUMOR INFILTRATION AND TRANSCRIPTIONAL HETEROGENEITY FROM CORE TO SINGLE-CELL DISPERSIONP01.24.B CORE2EDGE：一种人类胶质母细胞瘤类器官和脑片共培养模型，捕获从肿瘤核心到单细胞分散的肿瘤浸润和转录异质性
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errSchneider, M.; Potthoff, A.; Melhem, A.; Pregler, B. E.; Rodriguez-Gatica, J. E.; Thomas, J.; Friker, L. L.; Westhoff, M.; Ravi, V. M.; Heiland, D. H.; Schlitzer, A.; Pietsch, T.; Holzel, M.; Waha, A.; Vatter, H.; Schwarz, M. K.; Kubitscheck, U.; Herrlinger, U.
err分享
err收藏
BRAF/MAPK ACTIVATION AND NEURONAL LINEAGE PRIMING DEFINE A HYPOXIA-DRIVEN EVOLUTIONARY PROGRAM IN GLIOBLASTOMABRAF/MAPK激活和神经元谱系预置定义了胶质母细胞瘤中缺氧驱动的进化程序
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errVilla, G.; Conrad, N.; Kastner, G.; Kuckelhaus, J.; Benotmane, J.; Yabo, Y.; Zhang, J.; Sankowski, R.; Schnell, O.; Delev, D.; Neidert, N.; Heiland, D.
err分享
err收藏
IMMUNOLOGICAL CHANGES AFTER IDH-INHIBITION IN LOW-GRADE GLIOMA PATIENTSIDH抑制后低级别胶质瘤患者的免疫学变化
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errHeinrichs, P. G.; Neidert, N. N.; Kastner, G.; Muehlbauer, M. J.; Kong, Y.; Zhang, J.; Straehle, J.; Elrahal, A.; Grabis, E. L.; Mercan, Z.; Roelz, R.; Prinz, M.; Beck, J.; Heiland, D.; Benotmane, J. K.
err分享
err收藏
NEUROSURGERY IN GLIOBLASTOMA INDUCES CELL PLASTICITY, THERAPY RESISTANCE AND IMMUNOSUPPRESSION BY ISCHEMIC HYPOXIA神经外科手术在胶质母细胞瘤中通过缺血性缺氧诱导细胞可塑性、治疗抵抗和免疫抑制。
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errBallestin, A.; Reveilles, J.; Ribecco, V; Pichol-Thievend, C.; Thomas, A.; Anezo, O.; Bourmeau, G.; Borst, G. R.; Delobel, T.; Chemkhi, A.; Alanio, C.; Ballesta, A.; Isambert, H.; Cavalli, F. M.; Heiland, D.; Golebiewska, A.; Daubon, T.; Binder, Z. A.; van Rheenen, J.; Roncaroli, F.; Joseph, K.; Ravi, V. M.; Seano, G.
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RAPID AND OPTIMIZED INTRAOPERATIVE CLASSIFICATION OF CNS TUMORS BY NANOPORE SEQUENCING AND EPIGENETIC PROFILING利用纳米孔测序和表观遗传谱分析对CNS肿瘤进行快速且优化的术中分类
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errMerdan, A.; Peng, T.; Villa, G.; Masalha, W.; Delev, D.; Schnell, O.; Barany, L.; Heiland, D.
err分享
err收藏
MOLECULAR BARCODING OF GLIOBLASTOMA IN HUMAN ORGANOTYPIC CORTICAL SLICE CULTURE人脑胶质母细胞瘤在人脑器官型皮层切片培养中的分子条形码技术
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errKastner, G.; Muhlbauer, M.; Jung, J.; Langer, S.; Mueller, L.; Baginska, A.; Berger, P.; Dobersalske, C.; Ertmer, S.; Gerach, F. M.; Neidert, N.; Herrmann, K.; Rauschenbach, L.; van Hijfte, L.; Sure, U.; Kokkaliaris, K. D.; Gruner, B. M.; Heiland, D. H.; Scheffler, B.
err分享
err收藏
FLUID-SUPPRESSED APTW IMAGING BEFORE AND AFTER SURGERY IN GLIOBLASTOMA: A PROOF-OF-CONCEPT FOR DETECTING INFILTRATIVE AND RESIDUAL TUMOR BEYOND CONTRAST ENHANCEMENT胶质母细胞瘤术前和术后的流体抑制APTW成像：一种用于检测对比增强区域以外的浸润性和残留肿瘤的概念验证研究
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errSinger, L.; Heiland, P.; Karschnia, P.; Schure, J.; Delev, D.; Heiland, D. H.; Schnell, O.; Dorfler, A.; Zaiss, M.; Schmidt, M. A.
err分享
err收藏
GLIOBLASTOMA IN THE CONNECTOME: NEURAL PHENOTYPES PREDICT TUMOR INTEGRATION AND CONNECTIVITY连接组中的胶质母细胞瘤：神经表型预测肿瘤整合与连通性
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errMenzl, L.; Villa, G.; Yabo, Y.; Venkataramani, V.; Ricklefs, F. L.; Heiland, D.
err分享
err收藏
HIGH PERITUMORAL NETWORK CONNECTEDNESS IN GLIOBLASTOMA REVEALS A DISTINCT EPIGENETIC SIGNATURE AND IS ASSOCIATED WITH DECREASED OVERALL SURVIVAL.胶质母细胞瘤中高瘤周网络连接性揭示了一种独特的表观遗传学特征，并与总生存期缩短相关。
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errKerstin, J.; Ort, J.; Clusmann, H.; Drexler, R.; Heiland, D.; Ricklefs, F. L.; Delev, D.
err分享
err收藏
UNLOCKING 3D INSIGHTS: ENHANCED SURVIVAL AND IMAGING METHODS FOR HUMAN CORTICAL SLICE CULTURES解锁3D洞察：人类皮质切片培养物的增强生存和成像方法
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errWaldmann, J.; Menzl, L.; Villa, G.; Peng, T.; Hoffmann, L.; Heiland, D. H.; van Hijfte, L.
err分享
err收藏
IMMATURE NEURONAL NICHES AND ECM REMODELING CONTRIBUTE TO EPILEPTOGENICITY IN GANGLIOGLIOMAS: INSIGHTS FROM SPATIAL TRANSCRIPTOMICS不成熟的神经元微环境及细胞外基质重塑对神经节细胞瘤的致痫性有贡献：空间转录组学的见解
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
PREAI
errKueckelhaus, J.; Hoffmann, L.; Menstell, J.; Blumcke, I; Schnell, O.; Delev, D.; Heiland, D.
err分享
err收藏
SURGICAL RESECTION OF GLIOBLASTOMA INDUCES IMMUNOSUPPRESSION胶质母细胞瘤的外科切除术诱导免疫抑制
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errReveilles, J.; Ballestin, A.; Pichol-Thievend, C.; Thomas, A.; Ribecco, V; Anezo, O.; Bourmeau, G.; Blanchard, B.; Cavalli, F. M.; Borst, G. R.; Alanio, C.; Heiland, D.; Golebiewska, A.; Binder, Z. A.; van Rheenen, J.; Roncaroli, F.; Joseph, K.; Ravi, V. M.; Seano, G.
err分享
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