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Xiang Zhou 封面图

Xiang Zhou

Yale University教授邮箱:xiang.zhou.xz735@yale.edu
H指数:61
被引数:1.9万

个人简介

Research focuses on developing statistical and computational methods for genetic and genomic studies. These studies often involve large-scale and high-dimensional data; examples include genome-wide association studies and various functional genomic sequencing studies such as bulk and single cell RNAseq, bisulfite sequencing, as well as spatially resolved transcriptomics studies. By developing novel analytic methods, the scholar seeks to extract important information from these data and to advance the understanding of the genetic basis of phenotypic variation for various human diseases and disease related quantitative traits.

教育背景

  • 2010.12

    Duke University PhD

  • 2009.12

    Duke University MS

  • 2004.12

    Peking University BS

工作经历

暂无内容

荣誉奖项

暂无内容

Ancient DNA reveals pervasive directional selection across West Eurasia

古代DNA揭示西欧亚地区普遍的方向性选择

Nature
IF48.5
2026-04-150
PRE
Ali Akbari; Annabel Perry; Alison R. Barton; Mohammadreza Kariminejad; Steven Gazal; Zheng Li; Yating Zeng; Alissa Mittnik; Nick Patterson; Matthew Mah; Xiang Zhou; Alkes L. Price; Eric S. Lander; Ron Pinhasi; Nadin Rohland; Swapan Mallick; David Reich
Polygenic risk score for type 2 diabetes shows context-dependent effects across populations

2型糖尿病的多基因风险评分在人群中显示出依赖情境的影响

Nature Communications
IF15.7
2025-10-010
OAAI
Boya Guo; Yanwei Cai; Daeeun Kim; Roelof A. J. Smit; Zhe Wang; Kruthika R. Iyer; Austin T. Hilliard; Jeffrey Haessler; Ran Tao; K. Alaine Broadaway; Yujie Wang; Nikita Pozdeyev; Frederik F. Stæger; Chaojie Yang; Brett Vanderwerff; Amit D. Patki; Lauren Stalbow; Meng Lin; Nicholas Rafaels; Jonathan Shortt; Laura Wiley; Maggie Stanislawski; Jack Pattee; Lea Davis; Peter S. Straub; Megan M. Shuey; Nancy J. Cox; Nanette R. Lee; Marit E. Jørgensen; Peter Bjerregaard; Christina Larsen; Torben Hansen; Ida Moltke; James B. Meigs; Daniel O. Stram; Xianyong Yin; Xiang Zhou; Kyong-Mi Chang; Shoa L. Clarke; Rodrigo Guarischi-Sousa; Joanna Lankester; Philip S. Tsao; Steven Buyske; Mariaelisa Graff; Laura M. Raffield; Quan Sun; Lynne R. Wilkens; Christopher S. Carlson; Charles B. Easton; Simin Liu; JoAnn E. Manson; Loïc L. Marchand; Christopher A. Haiman; Karen L. Mohlke; Penny Gordon-Larsen; Anders Albrechtsen; Michael Boehnke; Stephen S. Rich; Ani Manichaikul; Jerome I. Rotter; Noha A. Yousri; Ryan M. Irvin; Chris Gignoux; Kari E. North; Ruth J. F. Loos; Themistocles L. Assimes; Ulrike Peters; Charles Kooperberg; Sridharan Raghavan; Heather M. Highland; Burcu F. Darst
Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancer

NSD3在DNA复制应激中的异构体特异性功能赋予了前列腺癌对PARP抑制剂的抗性

Molecular Cell
IF16.6
2025-06-260
PRE
Shouhai Zhu; Huanyao Gao; Dan Jiang; Guijie Guo; Jing Hou; Yiqun Han; Chao Zhang; Xiaoping Hu; Shreya Indulkar; Jake A. Kloeber; Qi Hu; Yanxia Jiang; Xiangyu Zeng; Yaobin Ouyang; Jing Lu; Ping Yin; Kuntian Luo; Jinzhou Huang; Zheming Wu; Bin Chen; Huaping Xiao; Sonja Dragojevic; Hongran Qin; Xiang Zhou; Jian Jin; Xinyi Tu; Liewei Wang; Zhenkun Lou
Depressive symptoms partially mediate the relationship between psychosocial factors and epigenetic age acceleration in a multi-racial/ ethnic sample of older adults

抑郁症状部分中介了心理社会因素与表观遗传年龄加速之间的关系，在一个多种族/族裔的老年人群样本中。

brain behavior and immunity
IF3.5
2025-05-010
OAAI
Opsasnick, Lauren A.; Zhao, Wei; Schmitz, Lauren L.; Ratliff, Scott M.; Faul, Jessica D.; Zhou, Xiang; Needham, Belinda L.; Smith, Jennifer A.

研究方向

Bayesian methodsmixed effects modelsspatial statisticsgraphical modelsintegrative modelingnon-parametric modelsstatistical computingmachine learningdeep learninghealth data scienceanalysis of high dimensional genetic and genomic datagenome-wide association studiesmethylation studiessingle cell RNA sequencing studiesspatial transcriptomics
J
Jennifer A. Smith
H 指数:104论文数:801被引数:6.6万
P
Ping Zeng
H 指数:38论文数:265被引数:9,056
Y
Ying Ma
H 指数:21论文数:78被引数:2,144
Z
Zhongshang Yuan
H 指数:28论文数:150被引数:2,408
L
Lulu Shang
H 指数:13论文数:46被引数:831
S
Shiquan Sun
H 指数:18论文数:79被引数:2,476
W
Wei Zhao
H 指数:62论文数:366被引数:2.6万
L
Lars G. Fritsche
H 指数:66论文数:364被引数:4.2万
F
Fuzhong Xue
H 指数:43论文数:348被引数:6,698
S
Snehal Patil
H 指数:20论文数:55被引数:3,319