Xiang Zhou - Publications, H-index & Citations

Xiang Zhou

orthopaedic hospital of guangdong province

61H指数

306论文数

1.9W被引数

收录论文 115

发表时间

scGPA: an LLM-assisted workflow for directional virtual gene perturbation analysis from single-cell transcriptomes scGPA：一种基于大型语言模型辅助的用于从单细胞转录组进行定向虚拟基因扰动分析的工作流程

BMC Genomics

IF3.7

2026-08-25

OAAI

Haijun Tang; Hening Li; Qinghao Zhao; Xiang Zhou; Lei Peng; Yangjie Cai; Rongzhen Lin; Yufeng Li; Yiyi Yuan; Wenyu Feng; Yun Liu; Zezheng Liu; Qingchu Li

Multivariate genetic analysis reveals three distinct pathological dimensions in musculoskeletal disorders 多变量遗传分析揭示肌肉骨骼疾病中的三种不同病理维度

Nature Communications

IF15.7

2026-04-21

OAAI

Weiming Gong; Yantong Guo; Xiubin Sun; Shukang Wang; Fuzhong Xue; Wei Zhao; Xiang Zhou; Lu Liu; Zhongshang Yuan

Ancient DNA reveals pervasive directional selection across West Eurasia 古代DNA揭示西欧亚地区普遍的方向性选择

Nature

IF48.5

2026-04-15

PREAI

Ali Akbari; Annabel Perry; Alison R. Barton; Mohammadreza Kariminejad; Steven Gazal; Zheng Li; Yating Zeng; Alissa Mittnik; Nick Patterson; Matthew Mah; Xiang Zhou; Alkes L. Price; Eric S. Lander; Ron Pinhasi; Nadin Rohland; Swapan Mallick; David Reich

FastCCC: a permutation-free framework for scalable, robust, and reference-based cell-cell communication analysis in single cell transcriptomics studies FastCCC: 一种无排列框架，用于单细胞转录组学研究中可扩展、鲁棒且基于参考的细胞间通信分析

Nature Communications

IF15.7

2025-12-13

OAAI

Siyu Hou; Wenjing Ma; Xiang Zhou

Full-length transcriptome analysis reveals molecular basis of sexual dimorphism in the palm pest Tirathaba rufivena Walker 全长转录组分析揭示了棕榈害虫Tirathaba rufivena Walker性别二型的分子基础

JOURNAL OF ASIA-PACIFIC ENTOMOLOGY

IF1.3

2025-11-01

PREAI

Guo, Jixing; Wang, Keying; Zhang, Xufeng; Yuan, Hongchao; Zhou, Xiang

Logica: A likelihood framework for cross-ancestry local genetic correlation estimation using summary statistics Logica: 基于汇总统计的跨族裔局部遗传相关估计的似然框架

The American Journal of Human Genetics

IF0

2025-10-23

PREAI

Boran Gao; Zheng Li; Xiang Zhou

Statistical construction of calibrated prediction intervals for polygenic score-based phenotype prediction 基于多基因分数的表型预测的校准预测区间统计构建

Nature Genetics

IF29

2025-10-13

OAAI

Chang Xu; Santhi K. Ganesh; Xiang Zhou

Polygenic risk score for type 2 diabetes shows context-dependent effects across populations 2型糖尿病的多基因风险评分在人群中显示出依赖情境的影响

Nature Communications

IF15.7

2025-10-01

OAAI

Boya Guo; Yanwei Cai; Daeeun Kim; Roelof A. J. Smit; Zhe Wang; Kruthika R. Iyer; Austin T. Hilliard; Jeffrey Haessler; Ran Tao; K. Alaine Broadaway; Yujie Wang; Nikita Pozdeyev; Frederik F. Stæger; Chaojie Yang; Brett Vanderwerff; Amit D. Patki; Lauren Stalbow; Meng Lin; Nicholas Rafaels; Jonathan Shortt; Laura Wiley; Maggie Stanislawski; Jack Pattee; Lea Davis; Peter S. Straub; Megan M. Shuey; Nancy J. Cox; Nanette R. Lee; Marit E. Jørgensen; Peter Bjerregaard; Christina Larsen; Torben Hansen; Ida Moltke; James B. Meigs; Daniel O. Stram; Xianyong Yin; Xiang Zhou; Kyong-Mi Chang; Shoa L. Clarke; Rodrigo Guarischi-Sousa; Joanna Lankester; Philip S. Tsao; Steven Buyske; Mariaelisa Graff; Laura M. Raffield; Quan Sun; Lynne R. Wilkens; Christopher S. Carlson; Charles B. Easton; Simin Liu; JoAnn E. Manson; Loïc L. Marchand; Christopher A. Haiman; Karen L. Mohlke; Penny Gordon-Larsen; Anders Albrechtsen; Michael Boehnke; Stephen S. Rich; Ani Manichaikul; Jerome I. Rotter; Noha A. Yousri; Ryan M. Irvin; Chris Gignoux; Kari E. North; Ruth J. F. Loos; Themistocles L. Assimes; Ulrike Peters; Charles Kooperberg; Sridharan Raghavan; Heather M. Highland; Burcu F. Darst

Towards improved fine-mapping of candidate causal variants 改进候选因果变量的精细映射

Nature Reviews Genetics

IF52

2025-07-28

PREAI

Zheng Li; Xiang Zhou

NG2 glia promote injured spinal cord repair through neuronal transdifferentiation and keratins expression in juvenile mice NG2胶质细胞通过神经元转分化及角蛋白表达促进幼年小鼠脊髓损伤修复

spine journal

IF0

2025-07-16

PREAI

Qing Zhao; Pianpian Fan; Qie Gu; Haoran Yang; Yongxu Xie; Shuaishuai Xia; Mingyu Lv; Xuemei Tan; Xiang Zhou; Qingchu Li

Efficient Mendelian randomization analysis with self-adaptive determination of sample structure and multiple pleiotropic effects 高效孟德尔随机化分析，包含自适应性确定样本结构和多重多效性效应。

american journal of human genetics

IF0

2025-07-10

PREAI

Liye Zhang; Lu Liu; Jiadong Ji; Ran Yan; Ping Guo; Weiming Gong; Fuzhong Xue; Xiang Zhou; Zhongshang Yuan

Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancer NSD3在DNA复制应激中的异构体特异性功能赋予了前列腺癌对PARP抑制剂的抗性

Molecular Cell

IF16.6

2025-06-26

PREAI

Shouhai Zhu; Huanyao Gao; Dan Jiang; Guijie Guo; Jing Hou; Yiqun Han; Chao Zhang; Xiaoping Hu; Shreya Indulkar; Jake A. Kloeber; Qi Hu; Yanxia Jiang; Xiangyu Zeng; Yaobin Ouyang; Jing Lu; Ping Yin; Kuntian Luo; Jinzhou Huang; Zheming Wu; Bin Chen; Huaping Xiao; Sonja Dragojevic; Hongran Qin; Xiang Zhou; Jian Jin; Xinyi Tu; Liewei Wang; Zhenkun Lou

Expanding biobank pharmacogenomics through machine learning calls of structural variation 通过机器学习识别结构变异以拓展生物样本库的药物基因组学

GENETICS

IF5.1

2025-05-09

PREAI

Vanderwerff, Brett; Pasternak, Amy L.; Fritsche, Lars G.; Bertucci-Richter, Emily; Patil, Snehal; Boehnke, Michael; Zhou, Xiang; Zollner, Sebastian; Hertz, Daniel L.; Zawistowski, Matthew

Depressive symptoms partially mediate the relationship between psychosocial factors and epigenetic age acceleration in a multi-racial/ ethnic sample of older adults 抑郁症状部分中介了心理社会因素与表观遗传年龄加速之间的关系，在一个多种族/族裔的老年人群样本中。

brain behavior and immunity

IF3.5

2025-05-01

OAAI

Opsasnick, Lauren A.; Zhao, Wei; Schmitz, Lauren L.; Ratliff, Scott M.; Faul, Jessica D.; Zhou, Xiang; Needham, Belinda L.; Smith, Jennifer A.

Exploring and mitigating shortcomings in single-cell differential expression analysis with a new statistical paradigm 探索并缓解单细胞差异表达分析中的不足，提出一种新的统计范式

GENOME BIOLOGY

IF9.4

2025-03-17

OAAI

Wu, Chih-Hsuan; Zhou, Xiang

Identification of key genes and variants associated with boar sperm freezability using whole genome resequencing 利用全基因组重测序鉴定与公猪精子冷冻保存能力相关的关键基因和变异位点

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2025-03-01

PREAI

Wang, Wenjun; Bai, Yifan; Wang, Xiaokang; Zhang, Jiajun; Li, Bushe; Zhang, Hejun; Zhou, Xiang; Liu, Bang

Neighborhood environment associations with cognitive function and structural brain measures in older African Americans

BMC MEDICINE

IF8.3

2025-01-13

OAAI

Chaar, Dima L.; Tu, Le; Moore, Kari; Du, Jiacong; Opsasnick, Lauren A.; Ratliff, Scott M.; Mosley, Thomas H.; Kardia, Sharon L. R.; Zhao, Wei; Zhou, Xiang; Roux, Ana V. Diez; Faruque, Fazlay S.; Butler, Kenneth R.; Smith, Jennifer A.

Stereo-seq of the prefrontal cortex in aging and Alzheimer's disease 前额叶皮层在衰老和阿尔茨海默病中的立体测序

NATURE COMMUNICATIONS

IF15.7

2025-01-08

OAAI

Gong, Yun; Haeri, Mohammad; Zhang, Xiao; Li, Yisu; Liu, Anqi; Wu, Di; Zhang, Qilei; Jazwinski, S. Michal; Zhou, Xiang; Wang, Xiaoying; Zhang, Kai; Jiang, Lindong; Chen, Yi-Ping; Yan, Xiaoxin; Swerdlow, Russell H.; Shen, Hui; Deng, Hong-Wen

Proteome-wide association studies for blood lipids and comparison with transcriptome-wide association studies 血脂的蛋白质组全关联研究及其与转录组全关联研究的比较

HUMAN GENETICS AND GENOMICS ADVANCES

IF3.6

2025-01-01

OAAI

Zhang, Daiwei; Gao, Boran; Feng, Qidi; Manichaikul, Ani; Peloso, Gina M.; Tracy, Russell P.; Durda, Peter; Taylor, Kent D.; Liu, Yongmei; Johnson, W. Craig; Gabriel, Stacey; Gupta, Namrata; Smith, Joshua D.; Aguet, Francois; Ardlie, Kristin G.; Blackwell, Thomas W.; Gerszten, Robert E.; Rich, Stephen S.; Rotter, Jerome I.; Scott, Laura J.; Zhou, Xiang; Lee, Seunggeun

Epigenome-wide mediation analysis of the relationship between psychosocial stress and cardiometabolic risk factors in the Health and Retirement Study (HRS)

CLINICAL EPIGENETICS

IF4.4

2024-12-18

OAAI

Opsasnick, Lauren A.; Zhao, Wei; Ratliff, Scott M.; Du, Jiacong; Faul, Jessica D.; Schmitz, Lauren L.; Zhou, Xiang; Needham, Belinda L.; Smith, Jennifer A.

研究方向