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Mechanostimulatory Platform for Improved CAR T Cell Immunotherapy 力学刺激平台用于改善CAR T细胞免疫疗法 Yassin, AA; Martin, CU; Le Saux, G; Pandey, A; Tzadka, S; Toledo, E; Pandit, JJ; Sherf, T; Nusbaum, I; Bhattachrya, B; Banerji, R; Greenshpan, Y; Abu Abu Ahmad, M; Radinsky, O; Sklartz, M; Gazit, R; Elkabets, M; Ghassemi, S; Cohen, O; Schvartzman, M; Porgador, A 分享 收藏
SlideCNA: spatial copy number alteration detection from Slide-seq-like spatial transcriptomics data SlideCNA: 从slide-seq-like空间转录组学数据中检测空间拷贝数改变 Zhang, Diane; Segerstolpe, Asa; Slyper, Michal; Waldman, Julia; Murray, Evan; Strasser, Robert; Watter, Jan; Cohen, Ofir; Ashenberg, Orr; Abravanel, Daniel; Jane-Valbuena, Judit; Mages, Simon; Lako, Ana; Helvie, Karla; Rozenblatt-Rosen, Orit; Rodig, Scott; Chen, Fei; Wagle, Nikhil; Regev, Aviv; Klughammer, Johanna 分享 收藏
A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features 跨临床病理特征的转移性乳腺癌活检的多模态单细胞和空间表达图 Klughammer, Johanna; Abravanel, Daniel L.; Segerstolpe, Asa; Blosser, Timothy R.; Goltsev, Yury; Cui, Yi; Goodwin, Daniel R.; Sinha, Anubhav; Ashenberg, Orr; Slyper, Michal; Vigneau, Sebastien; Jane-Valbuena, Judit; Alon, Shahar; Caraccio, Chiara; Chen, Judy; Cohen, Ofir; Cullen, Nicole; DelloStritto, Laura K.; Dionne, Danielle; Files, Janet; Frangieh, Allison; Helvie, Karla; Hughes, Melissa E.; Inga, Stephanie; Kanodia, Abhay; Lako, Ana; MacKichan, Colin; Mages, Simon; Moriel, Noa; Murray, Evan; Napolitano, Sara; Nguyen, Kyleen; Nitzan, Mor; Ortiz, Rebecca; Patel, Miraj; Pfaff, Kathleen L.; Porter, Caroline B. M.; Rotem, Asaf; Strauss, Sarah; Strasser, Robert; Thorner, Aaron R.; Turner, Madison; Wakiro, Isaac; Waldman, Julia; Wu, Jingyi; Zanudo, Jorge Gomez Tejeda; Zhang, Diane; Lin, Nancy U.; Tolaney, Sara M.; Winer, Eric P.; Boyden, Edward S.; Chen, Fei; Nolan, Garry P.; Rodig, Scott J.; Zhuang, Xiaowei; Rozenblatt-Rosen, Orit; Johnson, Bruce E.; Regev, Aviv; Wagle, Nikhil 分享 收藏
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Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments(vol 21, pg 879, 2019) Janiszewska, Michalina; Tabassum, Doris P.; Castano, Zafira; Cristea, Simona; Yamamoto, Kimiyo N.; Kingston, Natalie L.; Murphy, Katherine C.; Shu, Shaokun; Harper, Nicholas W.; Del Alcazar, Carlos Gil; Aleckovic, Masa; Ekram, Muhammad B.; Cohen, Ofir; Kwak, Minsuk; Qin, Yuanbo; Laszewski, Tyler; Luoma, Adrienne; Marusyk, Andriy; Wucherpfennig, Kai W.; Wagle, Nikhil; Fan, Rong; Michor, Franziska; Mcallister, Sandra S.; Polyak, Kornelia 分享 收藏
High FOXA1 levels induce ER transcriptional reprogramming, a pro-metastatic secretome, and metastasis in endocrine-resistant breast cancer Fu, Xiaoyong; Pereira, Resel; Liu, Chia -Chia; De Angelis, Carmine; Shea, Martin J.; Nanda, Sarmistha; Qin, Lanfang; Mitchell, Tamika; Cataldo, Maria L.; Veeraraghavan, Jamunarani; Sethunath, Vidyalakshmi; Giuliano, Mario; Gutierrez, Carolina; Gyorffy, Balazs; Trivedi, Meghana, V; Cohen, Ofir; Wagle, Nikhil; Nardone, Agostina; Jeselsohn, Rinath; Rimawi, Mothaffar F.; Osborne, C. Kent; Schiff, Rachel 分享 收藏
Functional binding of PD1 ligands predicts response to anti-PD1 treatment in patients with cancer Kaufman, Bar; Abramov, Orli; Ievko, Anna; Apple, Daria; Shlapobersky, Mark; Allon, Irit; Greenshpan, Yariv; Bhattachrya, Baisali; Cohen, Ofir; Charkovsky, Tatiana; Gayster, Alexandra; Shaco-Levy, Ruthy; Rouvinov, Keren; Livoff, Alejandro; Elkabets, Moshe; Porgador, Angel 分享 收藏
Super-enhancer-oriented integrative bioinformatics identifies aberrant KLF4 signaling in endocrine-resistant breast cancer (BC) Liu, Chia Chia; Qin, Lanfang; Sathe, Shanunak; Nanda, Sarmistha; Veeraraghavan, Jamunarani; Cohen, Ofir; Wagle, Nikhil; Rimawi, Mothaffar; Osborne, C. Kent; Fu, Xiaoyong; Schiff, Rachel 分享 收藏
Mutated HRAS Activates YAP1-AXL Signaling to Drive Metastasis of Head and Neck Cancer Jagadeeshan, Sankar; Prasad, Manu; Badarni, Mai; Ben-Lulu, Talal; Liju, Vijayasteltar Belsamma; Mathukkada, Sooraj; Saunders, Claire; Shnerb, Avital Beeri; Zorea, Jonathan; Yegodayev, Ksenia M.; Wainer, Monica; Vtorov, Liza; Allon, Irit; Cohen, Ofir; Gausdal, Gro; Friedmann-Morvinski, Dinorah; Cheong, Sok Ching; Ho, Alan L.; Rosenberg, Ari J.; Kessler, Linda; Burrows, Francis; Kong, Dexin; Grandis, Jennifer R.; Gutkind, J. Silvio; Elkabets, Moshe 分享 收藏
ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation Li, Zheqi; McGinn, Olivia; Wu, Yang; Bahreini, Amir; Priedigkeit, Nolan M.; Ding, Kai; Onkar, Sayali; Lampenfeld, Caleb; Sartorius, Carol A.; Miller, Lori; Rosenzweig, Margaret; Cohen, Ofir; Wagle, Nikhil; Richer, Jennifer K.; Muller, William J.; Buluwela, Laki; Ali, Simak; Bruno, Tullia C.; Vignali, Dario A. A.; Fang, Yusi; Zhu, Li; Tseng, George C.; Gertz, Jason; Atkinson, Jennifer M.; Lee, Adrian, V; Oesterreich, Steffi 分享 收藏
Targeting the FRA1-dependent transcriptional nexus in high FOXA1-driven endocrine-resistant and metastatic breast cancer Liu, Chia Chia; Qin, Lanfang; De Angelis, Carmine; Nanda, Sarmistha; Pereira, Resel; Shea, Martin J.; Nardone, Agostina; Jeselsohn, Rinath; Cohen, Ofir; Wagle, Nikhil; Liu, Zhijie; Rimawi, Mothaffar F.; Osborne, C. Kent; Schiff, Rachel; Fu, Xiaoyong 分享 收藏
Spatio-molecular dissection of the breast cancer metastatic microenvironment Abravanel, Daniel L.; Klughammer, Johanna; Blosser, Timothy; Goltsev, Yury; Jiang, Sizun; Bai, Yunjao; Murray, Evan; Alon, Shahar; Cui, Yi; Goodwin, Daniel R.; Sinha, Anubhav; Cohen, Ofir; Slyper, Michal; Ashenberg, Orr; Dionne, Danielle; Jane-Valbuena, Judit; Porter, Caroline BM.; Segerstolpe, Asa; Waldman, Julia; Vigneau, Sebastien; Helvie, Karla; Frangieh, Allison; DelloStritto, Laura; Patel, Miraj; We, Jingyi; Pfaff, Kathleen; Cullen, Nicole; Lako, Ana; Turner, Madison; Wakiro, Isaac; Napolitano, Sara; Kanodia, Abhay; Ortiz, Rebecca; MacKichan, Colin; Inga, Stephanie; Chen, Judy; Thorner, Aaron R.; Rotem, Asaf; Rodig, Scott; Chen, Fei; Boyden, Edward S.; Nolan, Garry P.; Zhuang, Xiaowei; Rozenblatt-Rosen, Orit; Johnson, Bruce E.; Regev, Aviv; Wagle, Nikhil 分享 收藏
Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma Jerby-Arnon, Livnat; Neftel, Cyril; Shore, Marni E.; Weisman, Hannah R.; Mathewson, Nathan D.; McBride, Matthew J.; Haas, Brian; Izar, Benjamin; Volorio, Angela; Boulay, Gaylor; Cironi, Luisa; Richman, Alyssa R.; Broye, Liliane C.; Gurski, Joseph M.; Luo, Christina C.; Mylvaganam, Ravindra; Nguyen, Lan; Mei, Shaolin; Melms, Johannes C.; Georgescu, Christophe; Cohen, Ofir; Buendia-Buendia, Jorge E.; Segerstolpe, Asa; Sud, Malika; Cuoco, Michael S.; Labes, Danny; Gritsch, Simon; Zollinger, Daniel R.; Ortogero, Nicole; Beechem, Joseph M.; Petur Nielsen, G.; Chebib, Ivan; Nguyen-Ngoc, Tu; Montemurro, Michael; Cote, Gregory M.; Choy, Edwin; Letovanec, Igor; Cherix, Stephane; Wagle, Nikhil; Sorger, Peter K.; Haynes, Alex B.; Mullen, John T.; Stamenkovic, Ivan; Rivera, Miguel N.; Kadoch, Cigall; Wucherpfennig, Kai W.; Rozenblatt-Rosen, Orit; Suva, Mario L.; Riggi, Nicolo; Regev, Aviv 分享 收藏
Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer Mao, Pingping; Cohen, Ofir; Kowalski, Kailey J.; Kusiel, Justin G.; Buendia-Buendia, Jorge E.; Cuoco, Michael S.; Exman, Pedro; Wander, Seth A.; Waks, Adrienne G.; Nayar, Utthara; Chung, Jon; Freeman, Samuel; Rozenblatt-Rosen, Orit; Miller, Vincent A.; Piccioni, Federica; Root, David E.; Regev, Aviv; Winer, Eric P.; Lin, Nancy U.; Wagle, Nikhil 分享 收藏
The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor-Positive Metastatic Breast Cancer 激素受体阳性转移性乳腺癌患者对细胞周期蛋白依赖性激酶4/6抑制剂的内在和获得性耐药的基因组景观 Wander, Seth A.; Cohent, Ofir; Gong, Xueqian; Johnson, Gabriela N.; Buendia-Buendia, Jorge E.; Lloyd, Maxwell R.; Kim, Dewey; Luo, Flora; Mao, Pingping; Helvie, Karla; Kowalski, Kalley J.; Nayar, Utthara; Waks, Adrienne G.; Parsons, Stephen H.; Martinez, Ricardo; Litchfield, Lacey M.; Ye, Xiang S.; Yu, Chunping; Jansen, Valerie M.; Stille, John R.; Smith, Patricia S.; Oakley, Gerard J.; Chu, Quincy S.; Batist, Gerald; Hughes, Melissa E.; Kremer, Jill D.; Garraway, Levi A.; Winer, Erik P.; Tolaney, Sara M.; Lin, Nancy U.; Buchanan, Sean G.; Wagle, Nikhil 分享 收藏
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors (vol 26, pg 792, 2020) Slyper, Michal; Porter, Caroline B. M.; Ashenberg, Orr; Waldman, Julia; Drokhlyansky, Eugene; Wakiro, Isaac; Smillie, Christopher; Smith-Rosario, Gabriela; Wu, Jingyi; Dionne, Danielle; Vigneau, Sebastien; Jane-Valbuena, Judit; Tickle, Timothy L.; Napolitano, Sara; Su, Mei-Ju; Patel, Anand G.; Karlstrom, Asa; Gritsch, Simon; Nomura, Masashi; Waghray, Avinash; Gohil, Satyen H.; Tsankov, Alexander M.; Jerby-Arnon, Livnat; Cohen, Ofir; Klughammer, Johanna; Rosen, Yanay; Gould, Joshua; Nguyen Lan; Hofree, Matan; Tramontozzi, Peter J.; Li, Bo; Wu, Catherine J.; Izar, Benjamin; Haq, Rizwan; Hodi, F. Stephen; Yoon, Charles H.; Hata, Aaron N.; Baker, Suzanne J.; Suva, Mario L.; Bueno, Raphael; Stover, Elizabeth H.; Clay, Michael R.; Dyer, Michael A.; Collins, Natalie B.; Matulonis, Ursula A.; Wagle, Nikhil; Johnson, Bruce E.; Rotem, Asaf; Rozenblatt-Rosen, Orit; Regev, Aviv 分享 收藏
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors Slyper, Michal; Porter, Caroline B. M.; Ashenberg, Orr; Waldman, Julia; Drokhlyansky, Eugene; Wakiro, Isaac; Smillie, Christopher; Smith-Rosario, Gabriela; Wu, Jingyi; Dionne, Danielle; Vigneau, Sebastien; Jane-Valbuena, Judit; Tickle, Timothy L.; Napolitano, Sara; Su, Mei-Ju; Patel, Anand G.; Karlstrom, Asa; Gritsch, Simon; Nomura, Masashi; Waghray, Avinash; Gohil, Satyen H.; Tsankov, Alexander M.; Jerby-Arnon, Livnat; Cohen, Ofir; Klughammer, Johanna; Rosen, Yanay; Gould, Joshua; Lan Nguyen; Hofree, Matan; Tramontozzi, Peter J.; Li, Bo; Wu, Catherine J.; Izar, Benjamin; Haq, Rizwan; Hodi, F. Stephen; Yoon, Charles H.; Hata, Aaron N.; Baker, Suzanne J.; Suva, Mario L.; Bueno, Raphael; Stover, Elizabeth H.; Clay, Michael R.; Dyer, Michael A.; Collins, Natalie B.; Matulonis, Ursula A.; Wagle, Nikhil; Johnson, Bruce E.; Rotem, Asaf; Rozenblatt-Rosen, Orit; Regev, Aviv 分享 收藏
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