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J

Joel T. Haas

INSERM
H指数:35
被引数:7,039

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PLCG2 downregulation impairs synaptic function and increases Alzheimer’s disease hallmarks in neuronal cultures

PLCγ2下调损害突触功能并增加神经元培养物中的阿尔茨海默病标志物

Nature Genetics
IF29
2026-08-140
OA
Audrey Coulon; Florian Rabiller; Mari Takalo; Avishek Roy; Alexandre Pelletier; Henna Martiskainen; Dolores Siedlecki-Wullich; Nina Lannette-Weimann; Naďa Majerníková; Arthur Grenon; Vance Gao; Anaël Erhardt; Anne Pernodet; Morgane Lemaire; Floriane Limoge; Pauline Walle; Tiago Mendes; Karine Guyot; Célia Lemeu; Lukas-Iohan Carvalho; Ana Raquel Melo de Farias; Marc Hulsman; Chloé Najdek; Alejandra Freire-Regatillo; Orthis Saha; Philippe Amouyel; Camille Charbonnier; Jean-François Deleuze; Orio Dols-Icardo; Heli Jeskanen; Roosa-Maria Willman; Teemu Kuulasmaa; Mitja Kurki; John Hardy; Sami Heikkinen; Henne Holstege; Petra Mäkinen; Gaël Nicolas; Simon Mead; Michael Wagner; Alfredo Ramirez; Tuomas Rauramaa; Aarno Palotie; Rebecca Sims; Hilkka Soininen; John van Swieten; Julie Williams; Céline Bellenguez; Carla Gelle; Erwan Lambert; Marcos R. Costa; Julia TCW; Enrico Glaab; Anne-Marie Ayral; Florie Demiautte; Benjamin Grenier-Boley; Manon Muntaner; Delphine Eberlé; Séverine Deforges; Joel T. Haas; Devrim Kilinc; Christophe Mulle; Julien Chapuis; Mikko Hiltunen; Julie Dumont; Jean-Charles Lambert
Liver Metabolomic Profiling Reveals Distinct Signatures Between Steatosis and Metabolic Dysfunction-Associated Steatohepatitis

肝脏代谢组学分析揭示了单纯脂肪变性与非酒精性脂肪性肝炎之间代谢特征的差异

Liver International
IF5.2
2026-02-120
OAAI
Saana Palomurto; Emily Flam; Dorota Kaminska; Kirsi A. Virtanen; Vesa Kärjä; Pirjo Käkelä; Päivi Pajukanta; Delphine Eberlé; Joel T. Haas; Violeta Raverdy; Robert Caiazzo; François Pattou; Bart Staels; Jussi Pihlajamäki; Ville Männistö
Integrative metagenomics and metabolomics reveal age-associated gut microbiota and metabolite alterations in a hamster model of COVID-19

整合宏基因组学和代谢组学揭示了COVID-19仓鼠模型中与年龄相关的肠道微生物群和代谢物改变

GUT MICROBES
IF11
2025-04-020
OA
Patrícia Brito Rodrigues; Vinícius de Rezende Rodovalho; Valentin Sencio; Nicolas Benech; Marybeth Creskey; Fabiola Silva Angulo; Lou Delval; Cyril Robil; Philippe Gosset; Arnaud Machelart; Joel Haas; Amandine Descat; Jean François Goosens; Delphine Beury; Florence Maurier; David Hot; Isabelle Wolowczuk; Harry Sokol; Xu Zhang; Marco Aurélio Ramirez Vinolo; François Trottein
Rev-erb-α antagonism in alveolar macrophages protects against pneumococcal infection in elderly mice

肺泡巨噬细胞中Rev-erb-α的拮抗作用可保护老年小鼠免受肺炎链球菌感染

CELL REPORTS
IF6.9
2025-02-011
OAAI
Angulo, Fabiola Silva; Joseph, Claudine Vanessa; Delval, Lou; Deruyter, Lucie; Heumel, Severine; Bicharel, Marie; Rodrigues, Patricia Brito; Sencio, Valentin; Bourguignon, Tom; Machado, Marina Gomes; Fourcot, Marie; Delhaye, Stephane; Salome-Desnoulez, Sophie; Valet, Philippe; Adnot, Serge; Wolowczuk, Isabelle; Sirard, Jean-Claude; Pichavant, Muriel; Staels, Bart; Haas, Joel T.; Gref, Ruxandra; Vandel, Jimmy; Machelart, Arnaud; Duez, Helene; Pourcet, Benoit; Trottein, Francois
Data-driven cluster analysis identifies distinct types of metabolic dysfunction-associated steatotic liver disease

数据驱动的聚类分析确定不同类型的代谢功能障碍相关的脂肪性肝病

NATURE MEDICINE
IF50
2024-12-090
OAAI
Raverdy, Violeta; Tavaglione, Federica; Chatelain, Estelle; Lassailly, Guillaume; De Vincentis, Antonio; Vespasiani-Gentilucci, Umberto; Qadri, Sami F.; Caiazzo, Robert; Verkindt, Helene; Saponaro, Chiara; Kerr-Conte, Julie; Baud, Gregory; Marciniak, Camille; Chetboun, Mikael; Oukhouya-Daoud, Naima; Blanck, Samuel; Vandel, Jimmy; Olsson, Lisa; Chakaroun, Rima; Gnemmi, Viviane; Leteurtre, Emmanuelle; Lefebvre, Philippe; Haas, Joel T.; Yki-Jarvinen, Hannele; Francque, Sven; Staels, Bart; Le Roux, Carel W.; Tremaroli, Valentina; Mathurin, Philippe; Marot, Guillemette; Romeo, Stefano; Pattou, Francois
Adipose tissue macrophage infiltration and hepatocyte stress increase GDF-15 throughout development of obesity to MASH
NATURE COMMUNICATIONS
IF15.7
2024-08-212
OAAI
L'homme, Laurent; Sermikli, Benan Pelin; Haas, Joel T.; Fleury, Sebastien; Quemener, Sandrine; Guinot, Valentine; Barreby, Emelie; Esser, Nathalie; Caiazzo, Robert; Verkindt, Helene; Legendre, Benjamin; Raverdy, Violeta; Cheval, Lydie; Paquot, Nicolas; Piette, Jacques; Legrand-Poels, Sylvie; Aouadi, Myriam; Pattou, Francois; Staels, Bart; Dombrowicz, David
Adipocyte-specific FXR-deficiency protects adipose tissue from oxidative stress and insulin resistance and improves glucose homeostasis (vol 69, pg 1, 2023)
MOLECULAR METABOLISM
IF6.6
2024-07-010
OAAI
Dehondt, Helene; Marino, Arianna; Butruille, Laura; Mogilenko, Denis A.; Loubota, Arielle C. Nzoussi; Chavez-Talavera, Oscar; Dorchies, Emilie; Vallez, Emmanuelle; Haas, Joel; Derudas, Bruno; Bongiovanni, Antonino; Tardivel, Meryem; Kuipers, Folkert; Lefebvre, Philippe; Lestavel, Sophie; Tailleux, Anne; Dombrowicz, David; Caron, Sandrine; Staels, Bart
Shotgun metagenomics and systemic targeted metabolomics highlight indole-3-propionic acid as a protective gut microbial metabolite against influenza infection

Shot弹枪宏基因组学和系统靶向代谢组学强调indole-3-propionic酸是一种保护性肠道微生物代谢产物，可抵抗流感感染

GUT MICROBES
IF11
2024-03-065
OAAI
Heumel, Severine; Rodovalho, Vinicius de Rezende; Urien, Charlotte; Specque, Florian; Rodrigues, Patricia Brito; Robil, Cyril; Delval, Lou; Sencio, Valentin; Descat, Amandine; Deruyter, Lucie; Ferreira, Stephanie; Machado, Marina Gomes; Barthelemy, Adeline; Angulo, Fabiola Silva; Haas, Joel. T.; Goosens, Jean Francois; Wolowczuk, Isabelle; Grangette, Corinne; Rouille, Yves; Grimaud, Ghjuvan; Lenski, Marie; Hennart, Benjamin; Vinolo, Marco Aurelio Ramirez; Trottein, Francois
The ubiquitin-like modifier FAT10 is induced in MASLD and impairs the lipid-regulatory activity of PPARα
METABOLISM-CLINICAL AND EXPERIMENTAL
IF11.9
2024-02-011
OA
Clavreul, Ludivine; Bernard, Lucie; Cotte, Alexia K.; Hennuyer, Nathalie; Bourouh, Cyril; Devos, Claire; Helleboid, Audrey; Haas, Joel T.; Verrijken, An; Gheeraert, Celine; Derudas, Bruno; Guille, Loic; Chevalier, Julie; Eeckhoute, Jerome; Vallez, Emmanuelle; Dorchies, Emilie; Van Gaal, Luc; Lassailly, Guillaume; Francque, Sven; Staels, Bart; Paumelle, Rejane
Time-of-day-dependent variation of the human liver transcriptome and metabolome is disrupted in MASLD
JHEP REPORTS
IF7.5
2024-01-012
OAAI
Johanns, Manuel; Haas, Joel T.; Raverdy, Violetta; Vandel, Jimmy; Chevalier-Dubois, Julie; Guille, Loic; Derudas, Bruno; Legendre, Benjamin; Caiazzo, Robert; Verkindt, Helene; Gnemmi, Viviane; Leteurtre, Emmanuelle; Derhourhi, Mehdi; Bonnefond, Amelie; Froguel, Philippe; Eeckhoute, Jerome; Lassailly, Guillaume; Mathurin, Philippe; Pattou, Francois; Staels, Bart; Lefebvre, Philippe
Roux-en-Y gastric bypass induces hepatic transcriptomic signatures and plasma metabolite changes indicative of improved cholesterol homeostasis
JOURNAL OF HEPATOLOGY
IF33
2023-10-017
PRE
Lalloyer, Fanny; Mogilenko, Denis A.; Verrijken, Ann; Haas, Joel T.; Lamaziere, Antonin; Kouach, Mostafa; Descat, Amandine; Caron, Sandrine; Vallez, Emmanuelle; Derudas, Bruno; Gheeraert, Celine; Bauge, Eric; Despres, Gaetan; Dirinck, Eveline; Tailleux, Anne; Dombrowicz, David; Van Gaal, Luc; Eeckhoute, Jerome; Lefebvre, Philippe; Goossens, Jean-Francois; Francque, Sven; Staels, Bart
Adipocyte-specific FXR-deficiency protects adipose tissue from oxidative stress and insulin resistance and improves glucose homeostasis

脂肪细胞特异性FXR缺乏可保护脂肪组织免受氧化应激和胰岛素抵抗，并改善葡萄糖稳态

MOLECULAR METABOLISM
IF6.6
2023-03-0111
OAAI
Dehondt, Helene; Marino, Arianna; Butruille, Laura; Mogilenko, Denis A.; Loubota, Arielle C. Nzoussi; Chavez-Talavera, Oscar; Dorchies, Emilie; Vallez, Emmanuelle; Haas, Joel; Derudas, Bruno; Bongiovanni, Antonino; Tardivel, Meryem; Kuipers, Folkert; Lefebvre, Philippe; Lestavel, Sophie; Tailleux, Anne; Dombrowicz, David; Caron, Sandrine; Staels, Bart
Functional genomics uncovers the transcription factor BNC2 as required for myofibroblastic activation in fibrosis

功能基因组学揭示了纤维化中肌成纤维细胞激活所需的转录因子BNC2

NATURE COMMUNICATIONS
IF15.7
2022-09-1016
OAAI
Bobowski-Gerard, Marie; Boulet, Clemence; Zummo, Francesco P.; Dubois-Chevalier, Julie; Gheeraert, Celine; Saleh, Mohamed Bou; Strub, Jean-Marc; Farce, Amaury; Ploton, Maheul; Guille, Loic; Vandel, Jimmy; Bongiovanni, Antonino; Very, Ninon; Woitrain, Eloise; Deprince, Audrey; Lalloyer, Fanny; Bauge, Eric; Ferri, Lise; Ntandja-Wandji, Line-Carolle; Cotte, Alexia K.; Grangette, Corinne; Vallez, Emmanuelle; Cianferani, Sarah; Raverdy, Violeta; Caiazzo, Robert; Gnemmi, Viviane; Leteurtre, Emmanuelle; Pourcet, Benoit; Paumelle, Rejane; Ravnskjaer, Kim; Lassailly, Guillaume; Haas, Joel T.; Mathurin, Philippe; Pattou, Francois; Dubuquoy, Laurent; Staels, Bart; Lefebvre, Philippe; Eeckhoute, Jerome
Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride-rich lipoprotein metabolism
HEPATOLOGY
IF15.8
2022-07-156
OAAI
Deprince, Audrey; Hennuyer, Nathalie; Kooijman, Sander; Pronk, Amanda C. M.; Bauge, Eric; Lienard, Viktor; Verrijken, An; Dirinck, Eveline; Vonghia, Luisa; Woitrain, Eloise; Kloosterhuis, Niels J.; Marez, Eleonore; Jacquemain, Pauline; Wolters, Justina C.; Lalloyer, Fanny; Eberle, Delphine; Quemener, Sandrine; Vallez, Emmanuelle; Tailleux, Anne; Kouach, Mostafa; Goossens, Jean-Francois; Raverdy, Violeta; Derudas, Bruno; Kuivenhoven, Jan Albert; Croyal, Mikael; van de Sluis, Bart; Francque, Sven; Pattou, Francois; Rensen, Patrick C. N.; Staels, Bart; Haas, Joel T.
The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression

需要肝细胞胰岛素受体来编程肝脏时钟和节律性基因表达

CELL REPORTS
IF6.9
2022-04-0114
OA
Fougeray, Tiffany; Polizzi, Arnaud; Regnier, Marion; Fougerat, Anne; Ellero-Simatos, Sandrine; Lippi, Yannick; Smati, Sarra; Lasserre, Frederic; Tramunt, Blandine; Huillet, Marine; Dopavogui, Leonie; Salvi, Juliette; Nedelec, Emmanuelle; Gigot, Vincent; Smith, Lorraine; Naylies, Claire; Sommer, Caroline; Haas, Joel T.; Wahli, Walter; Duez, Helene; Gourdy, Pierre; Gamet-Payrastre, Laurence; Benani, Alexandre; Burnol, Anne-Francoise; Loiseau, Nicolas; Postic, Catherine; Montagner, Alexandra; Guillou, Herve

研究方向

暂未获取到该数据
B
Bart Staels
H 指数:167论文数:1,195被引数:11.0万
P
Philippe Lefèbvre
H 指数:56论文数:282被引数:1.6万
S
Sven Francque
H 指数:79论文数:456被引数:3.4万
E
Emmanuelle Vallez
H 指数:22论文数:90被引数:2,133
D
David Dombrowicz
H 指数:54论文数:224被引数:8,641
V
Violeta Raverdy
H 指数:36论文数:131被引数:7,194
R
Robert V. Farese
H 指数:110论文数:314被引数:4.8万
A
Anne Tailleux
H 指数:47论文数:157被引数:8,954
F
François Pattou
H 指数:95论文数:962被引数:4.2万
B
Bruno Derudas
H 指数:25论文数:49被引数:4,375