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P

Philippe Lefèbvre

INSERM
H指数:56
被引数:1.6万

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Derepression of the epithelial transcription factor GRHL2 promotes direct hepatocyte-to-cholangiocyte transdifferentiation

上皮转录因子GRHL2的去抑制促进了直接的肝细胞到胆管细胞的转分化

PLOS BIOLOGY
IF7.2
2025-12-120
PRE
Vasseur, Ludivine; Gheeraert, Celine; Dubois-Chevalier, Julie; Very, Ninon; Guille, Loic; Bou Saleh, Mohamed; Boulet, Clemence; Sobolewski, Cyril; Loyer, Pascal; Berthier, Alexandre; Legrand, Noemie; Corlu, Anne; Gnemmi, Viviane; Lasailly, Guillaume; Leteurtre, Emmanuelle; Galinousky, Dmitry; Bongiovanni, Antonino; Taront, Solenne; Toft, Nicolaj I.; Grontved, Lars; Tulasne, David; Furlan, Alessandro; Ntandja-Wandji, Line Carolle; Staels, Bart; Lefebvre, Philippe; Dubuquoy, Laurent; Eeckhoute, Jerome
Intrahepatic levels of microbiome-derived hippurate associates with improved metabolic dysfunction-associated steatotic liver disease

微生物组衍生的马尿酸盐的肝内水平与改善的代谢功能障碍相关的脂肪性肝病相关

MOLECULAR METABOLISM
IF6.6
2025-02-010
OAAI
Deslande, Maxime; Puig-Castellvi, Francesc; Castro-Dionicio, Ines; Pacheco-Tapia, Romina; Raverdy, Violeta; Caiazzo, Robert; Lassailly, Guillaume; Leloire, Audrey; Andrikopoulos, Petros; Kahoul, Yasmina; Zaibi, Nawel; Toussaint, Benedicte; Oger, Frederik; Gambardella, Nicolas; Lefebvre, Philippe; Derhourhi, Mehdi; Amanzougarene, Souhila; Staels, Bart; Pattou, Francois; Froguel, Philippe; Bonnefond, Amelie; Dumas, Marc-Emmanuel
Data-driven cluster analysis identifies distinct types of metabolic dysfunction-associated steatotic liver disease

数据驱动的聚类分析确定不同类型的代谢功能障碍相关的脂肪性肝病

NATURE MEDICINE
IF50
2024-12-090
OAAI
Raverdy, Violeta; Tavaglione, Federica; Chatelain, Estelle; Lassailly, Guillaume; De Vincentis, Antonio; Vespasiani-Gentilucci, Umberto; Qadri, Sami F.; Caiazzo, Robert; Verkindt, Helene; Saponaro, Chiara; Kerr-Conte, Julie; Baud, Gregory; Marciniak, Camille; Chetboun, Mikael; Oukhouya-Daoud, Naima; Blanck, Samuel; Vandel, Jimmy; Olsson, Lisa; Chakaroun, Rima; Gnemmi, Viviane; Leteurtre, Emmanuelle; Lefebvre, Philippe; Haas, Joel T.; Yki-Jarvinen, Hannele; Francque, Sven; Staels, Bart; Le Roux, Carel W.; Tremaroli, Valentina; Mathurin, Philippe; Marot, Guillemette; Romeo, Stefano; Pattou, Francois
Adipocyte-specific FXR-deficiency protects adipose tissue from oxidative stress and insulin resistance and improves glucose homeostasis (vol 69, pg 1, 2023)
MOLECULAR METABOLISM
IF6.6
2024-07-010
OAAI
Dehondt, Helene; Marino, Arianna; Butruille, Laura; Mogilenko, Denis A.; Loubota, Arielle C. Nzoussi; Chavez-Talavera, Oscar; Dorchies, Emilie; Vallez, Emmanuelle; Haas, Joel; Derudas, Bruno; Bongiovanni, Antonino; Tardivel, Meryem; Kuipers, Folkert; Lefebvre, Philippe; Lestavel, Sophie; Tailleux, Anne; Dombrowicz, David; Caron, Sandrine; Staels, Bart
O-GlcNAcylation controls pro-fibrotic transcriptional regulatory signaling in myofibroblasts

O-glcnacylation控制肌成纤维细胞中的促纤维化转录调节信号传导

CELL DEATH & DISEASE
IF9.6
2024-06-033
OAAI
Very, Ninon; Boulet, Clemence; Gheeraert, Celine; Berthier, Alexandre; Johanns, Manuel; Bou Saleh, Mohamed; Guille, Loic; Bray, Fabrice; Strub, Jean-Marc; Bobowski-Gerard, Marie; Zummo, Francesco P.; Vallez, Emmanuelle; Molendi-Coste, Olivier; Woitrain, Eloise; Cianferani, Sarah; Montaigne, David; Ntandja-Wandji, Line Carolle; Dubuquoy, Laurent; Dubois-Chevalier, Julie; Staels, Bart; Lefebvre, Philippe; Eeckhoute, Jerome
Genetic Evidence of Causal Relation Between Intestinal Glucose Absorption and Early Postprandial Glucose Response: A Mendelian Randomization Study
DIABETES
IF7.5
2024-03-180
OAAI
Peschard, Simon; Raverdy, Violeta; Bauvin, Pierre; Goutchtat, Rebecca; Touche, Veronique; Derudas, Bruno; Gheeraert, Celine; Dubois-Chevalier, Julie; Caiazzo, Robert; Baud, Gregory; Marciniak, Camille; Verkindt, Helene; Daoud, Naima Oukhouya; Le Roux, Carel W.; Lefebvre, Philippe; Staels, Bart; Lestavel, Sophie; Pattou, Francois
Time-of-day-dependent variation of the human liver transcriptome and metabolome is disrupted in MASLD
JHEP REPORTS
IF7.5
2024-01-012
OAAI
Johanns, Manuel; Haas, Joel T.; Raverdy, Violetta; Vandel, Jimmy; Chevalier-Dubois, Julie; Guille, Loic; Derudas, Bruno; Legendre, Benjamin; Caiazzo, Robert; Verkindt, Helene; Gnemmi, Viviane; Leteurtre, Emmanuelle; Derhourhi, Mehdi; Bonnefond, Amelie; Froguel, Philippe; Eeckhoute, Jerome; Lassailly, Guillaume; Mathurin, Philippe; Pattou, Francois; Staels, Bart; Lefebvre, Philippe
Combining diabetes, sex, and menopause as meaningful clinical features associated with NASH and liver fibrosis in individuals with class II and III obesity: A retrospective cohort study
OBESITY
IF4.7
2023-11-216
OAAI
Raverdy, Violeta; Chatelain, Estelle; Lasailly, Guillaume; Caiazzo, Robert; Vandel, Jimmy; Verkindt, Helene; Marciniak, Camille; Legendre, Benjamin; Bauvin, Pierre; Oukhouya-Daoud, Naima; Baud, Gregory; Chetboun, Mikael; Vantyghem, Marie-Christine; Gnemmi, Viviane; Leteurtre, Emmanuelle; Staels, Bart; Lefebvre, Philippe; Mathurin, Philippe; Marot, Guillemette; Pattou, Francois
Roux-en-Y gastric bypass induces hepatic transcriptomic signatures and plasma metabolite changes indicative of improved cholesterol homeostasis
JOURNAL OF HEPATOLOGY
IF33
2023-10-017
PRE
Lalloyer, Fanny; Mogilenko, Denis A.; Verrijken, Ann; Haas, Joel T.; Lamaziere, Antonin; Kouach, Mostafa; Descat, Amandine; Caron, Sandrine; Vallez, Emmanuelle; Derudas, Bruno; Gheeraert, Celine; Bauge, Eric; Despres, Gaetan; Dirinck, Eveline; Tailleux, Anne; Dombrowicz, David; Van Gaal, Luc; Eeckhoute, Jerome; Lefebvre, Philippe; Goossens, Jean-Francois; Francque, Sven; Staels, Bart
Adipocyte-specific FXR-deficiency protects adipose tissue from oxidative stress and insulin resistance and improves glucose homeostasis

脂肪细胞特异性FXR缺乏可保护脂肪组织免受氧化应激和胰岛素抵抗，并改善葡萄糖稳态

MOLECULAR METABOLISM
IF6.6
2023-03-0111
OAAI
Dehondt, Helene; Marino, Arianna; Butruille, Laura; Mogilenko, Denis A.; Loubota, Arielle C. Nzoussi; Chavez-Talavera, Oscar; Dorchies, Emilie; Vallez, Emmanuelle; Haas, Joel; Derudas, Bruno; Bongiovanni, Antonino; Tardivel, Meryem; Kuipers, Folkert; Lefebvre, Philippe; Lestavel, Sophie; Tailleux, Anne; Dombrowicz, David; Caron, Sandrine; Staels, Bart
DPP9 as a Potential Novel Mediator in Gastrointestinal Virus Infection

DPP9作为胃肠道病毒感染的潜在新型介质

ANTIOXIDANTS
IF6.6
2022-11-034
OAAI
del Castillo-Izquierdo, Angela; Maria Moreno-Navarrete, Jose; Latorre, Jessica; Arnoriaga-Rodriguez, Maria; Ballanti, Marta; Monteleone, Giovanni; Paoluzi, Omero Alessandro; Mingrone, Geltrude; Puig, Josep; Ramos, Rafael; Garre-Olmo, Josep; Jove, Mariona; Pamplona, Reinald; Portero-Otin, Manuel; Sol, Joaquim; Lefebvre, Philippe; Staels, Bart; Federici, Massimo; Manuel Fernandez-Real, Jose; Mayneris-Perxachs, Jordi

研究方向

暂未获取到该数据
B
Bart Staels
H 指数:167论文数:1,195被引数:11.0万
J
Jérôme Eeckhoute
H 指数:43论文数:111被引数:2.9万
C
Céline Gheeraert
H 指数:24论文数:50被引数:2,039
J
Julie Dubois‐Chevalier
H 指数:15论文数:39被引数:793
F
François Pattou
H 指数:95论文数:962被引数:4.2万
J
Joel T. Haas
H 指数:35论文数:93被引数:7,037
H
Hélène Dehondt
H 指数:21论文数:33被引数:2,180
A
Alexandre Berthier
H 指数:12论文数:39被引数:1,034
B
Bruno Derudas
H 指数:25论文数:49被引数:4,375
B
Bruno Lefebvre
H 指数:27论文数:61被引数:2,776