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F

Frank J. Lowery

national institutes of health
H指数:26
被引数:4,586

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Identification of HLA class II-restricted T cell receptors against shared PIK3CA mutations in patients with epithelial cancers

鉴定在患有上皮癌的患者中针对共享PIK3CA突变的HLA-II类限制性T细胞受体

Cancer Immunology, Immunotherapy
IF0
2025-12-180
OAAI
S. M. Rafiqul Islam; Samantha Seitter; Maria Parkhurst; Frank J. Lowery; Miaki Fukuhara; Sanghyun P. Kim; Noam Levin; Jared J. Gartner; Satyajit Ray; Todd Prickett; Victoria Hill; Paul F. Robbins; Stephanie L. Goff; Steven A. Rosenberg; Nikolaos Zacharakis
A platform for multisite immune profiling of premetastatic pancreatic cancer at single-cell resolution

一个用于多站点免疫图谱绘制的平台，可在单细胞分辨率下分析癌前胰腺癌的转移前状态

cancer immunology immunotherapy
IF0
2025-08-230
OAAI
Elishama N. Kanu; Ashley A. Fletcher; Jiayin Bao; Ethan S. Agritelley; Julia Button; Austin M. Eckhoff; Karrie Comatas; Tao Wang; Bin-Jin Hwang; Michael E. Lidsky; Sabino Zani; Dan G. Blazer; Peter J. Allen; Zhicheng Ji; Frank J. Lowery; Sri Krishna; Nicholas D. Klemen; Daniel P. Nussbaum; Erika J. Crosby
Neoantigen-specific tumor-infiltrating lymphocytes in gastrointestinal cancers: a phase 2 trial (Apr, 10.1038/s41591-025-03627-5, 2025)

胃肠癌中新抗原特异性肿瘤浸润淋巴细胞: 一项2期试验 (4月，10.1038/s41591-025-03627-5，2025)

NATURE MEDICINE
IF50
2025-04-150
PRE
Lowery, Frank J.; Goff, Stephanie L.; Gasmi, Billel; Parkhurst, Maria R.; Ratnam, Nivedita M.; Halas, Hyunmi K.; Shelton, Thomas E.; Langhan, Michelle M.; Bhasin, Aarushi; Dinerman, Aaron J.; Dulemba, Victoria; Goldlust, Ian S.; Gustafson, Alexandra M.; Hakim, Abraham A.; Hitscherich, Kyle J.; Kenney, Lisa M.; Levy, Lior; Rault-Wang, Juliette G.; Bera, Alakesh; Ray, Satyajit; Seavey, Courtney D.; Hoang, Chuong D.; Hernandez, Jonathan M.; Gartner, Jared J.; Sindiri, Sivasish; Prickett, Todd D.; McIntyre, Lori S.; Krishna, Sri; Robbins, Paul F.; Klemen, Nicholas D.; Kwong, Mei Li M.; Yang, James C.
Neoantigen-specific tumor-infiltrating lymphocytes in gastrointestinal cancers: a phase 2 trial

胃肠道癌症中的新抗原特异性肿瘤浸润淋巴细胞：一项2期临床试验

NATURE MEDICINE
IF50
2025-04-011
PRE
Lowery, Frank J.; Goff, Stephanie L.; Gasmi, Billel; Parkhurst, Maria R.; Ratnam, Nivedita M.; Halas, Hyunmi K.; Shelton, Thomas E.; Langhan, Michelle M.; Bhasin, Aarushi; Dinerman, Aaron J.; Dulemba, Victoria; Goldlust, Ian S.; Gustafson, Alexandra M.; Hakim, Abraham A.; Hitscherich, Kyle J.; Kenney, Lisa M.; Levy, Lior; Rault-Wang, Juliette G.; Bera, Alakesh; Ray, Satyajit; Seavey, Courtney D.; Hoang, Chuong D.; Hernandez, Jonathan M.; Gartner, Jared J.; Sindiri, Sivasish; Prickett, Todd D.; Mcintyre, Lori S.; Krishna, Sri; Robbins, Paul F.; Klemen, Nicholas D.; Kwong, Mei Li M.; Yang, James C.
Astrocyte-induced Cdk5 expedites breast cancer brain metastasis by suppressing MHC-I expression to evade immune recognition

星形胶质细胞诱导的Cdk5通过抑制mhc-i表达逃避免疫识别促进乳腺癌脑转移

NATURE CELL BIOLOGY
IF19.1
2024-09-201
PRE
Yuzhalin, Arseniy E.; Lowery, Frank J.; Saito, Yohei; Yuan, Xiangliang; Yao, Jun; Duan, Yimin; Ding, Jingzhen; Acharya, Sunil; Zhang, Chenyu; Fajardo, Abigail; Chen, Hao-Nien; Wei, Yongkun; Sun, Yutong; Zhang, Lin; Xiao, Yi; Li, Ping; Lorenzi, Philip L.; Huse, Jason T.; Fan, Huihui; Zhao, Zhongming; Hung, Mien-Chie; Yu, Dihua
Single-cell and spatial analysis of the immune landscape unveils a subset of potentially tumor-reactive T cells in patients with localized PDAC
CANCER RESEARCH
IF16.6
2024-09-150
PRE
Kanu, Elishama N.; Fletcher, Ashley A.; Krishna, Sri; Lowery, Frank J.; Zhuang, Haotian; Agritelley, Ethan S.; Bao, Jiayin; Eckhoff, Austin M.; Comatas, Karrie; Wang, Tao; Hwang, Bin-Jin; Lidsky, Michael E.; Zani, Sabino; Blazer, Dan G., III; Allen, Peter J.; Klemen, Nicholas D.; Ji, Zhicheng; Nussbaum, Daniel P.; Crosby, Erika J.
Adoptive transfer of personalized neoantigen-reactive TCR-transduced T cells in metastatic colorectal cancer: phase 2 trial interim results

转移性结直肠癌中个性化新抗原反应性TCR转导T细胞的过继转移: 2期试验中期结果

NATURE MEDICINE
IF50
2024-07-114
OA
Parkhurst, Maria; Goff, Stephanie L.; Lowery, Frank J.; Beyer, Rachel K.; Halas, Hyunmi; Robbins, Paul F.; Prickett, Todd D.; Gartner, Jared J.; Sindiri, Sivasish; Krishna, Sri; Zacharakis, Nikolaos; Ngo, Lien; Ray, Satyajit; Bera, Alakesh; Shepherd, Ryan; Levin, Noam; Kim, Sanghyun P.; Copeland, Amy; Nah, Shirley; Levi, Shoshana; Parikh, Neilesh; Kwong, Mei Li M.; Klemen, Nicholas D.; Yang, James C.; Rosenberg, Steven A.
Neoantigen-specific stimulation of tumor-infiltrating lymphocytes enables effective TCR isolation and expansion while preserving stem-like memory phenotypes

肿瘤浸润淋巴细胞的新抗原特异性刺激可实现有效的TCR隔离和扩增，同时保留干细胞样记忆表型

JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2024-05-302
OAAI
Levin, Noam; Kim, Sanghyun P.; Marquardt, Charles A.; Vale, Nolan R.; Yu, Zhiya; Sindiri, Sivasish; Gartner, Jared J.; Parkhurst, Maria; Krishna, Sri; Lowery, Frank J.; Zacharakis, Nikolaos; Levy, Lior; Prickett, Todd D.; Benzine, Tiffany; Ray, Satyajit; Masi, Robert, V; Gasmi, Billel; Li, Yong; Islam, Rafiqul; Bera, Alakesh; Goff, Stephanie L.; Robbins, Paul F.; Rosenberg, Steven A.
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade
MED
IF11.8
2022-10-0125
OA
Palmer, Douglas C.; Webber, Beau R.; Patel, Yogin; Johnson, Matthew J.; Kariya, Christine M.; Lahr, Walker S.; Parkhurst, Maria R.; Gartner, Jared J.; Prickett, Todd D.; Lowery, Frank J.; Kishton, Rigel J.; Gurusamy, Devikala; Franco, Zulmarie; Vodnala, Suman K.; Diers, Miechaleen D.; Wolf, Natalie K.; Slipek, Nicholas J.; McKenna, David H.; Sumstad, Darin; Viney, Lydia; Henley, Tom; Burckstummer, Tilmann; Baker, Oliver; Hu, Ying; Yan, Chunhua; Meerzaman, Daoud; Padhan, Kartik; Lo, Winnie; Malekzadeh, Parisa; Jia, Li; Deniger, Drew C.; Patel, Shashank J.; Robbins, Paul F.; McIvor, R. Scott; Choudhry, Modassir; Rosenberg, Steven A.; Moriarity, Branden S.; Restifo, Nicholas P.
Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers

来自转移性人类癌症的抗肿瘤新抗原反应性T细胞的分子特征

Science
IF45.8
2022-01-010
OA
Frank J. Lowery; Sri Krishna; Rami Yossef; Neilesh B. Parikh; Praveen D. Chatani; Nikolaos Zacharakis; Maria R. Parkhurst; Noam Levin; Sivasish Sindiri; Abraham Sachs; Kyle Joseph Hitscherich; Zhiya Yu; Nolan R. Vale; Yong‐Chen Lu; Zhili Zheng; Li Jia; Jared J. Gartner; Victoria K. Hill; Amy R. Copeland; Shirley Nah; Robert V. Masi; Billel Gasmi; Scott Kivitz; Biman C. Paria; Maria Florentin; Sanghyun Peter Kim; Ken‐ichi Hanada; Yong F. Li; Lien T. Ngo; Satyajit Ray; Mackenzie L. Shindorf; Shoshana T. Levi; Ryan Shepherd; Chris Toy; Anup Y. Parikh; Todd D. Prickett; Michael C. Kelly; Rachel K. Beyer; Stephanie L. Goff; James Chih-Hsin Yang; Paul F. Robbins; Steven A. Rosenberg
mRNA vaccine-induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2020-10-05289
OA
Cafri, Gal; Gartner, Jared J.; Zaks, Tal; Hopson, Kristen; Levin, Noam; Paria, Biman C.; Parkhurst, Maria R.; Yossef, Rami; Lowery, Frank J.; Jafferji, Mohammad S.; Prickett, Todd D.; Goff, Stephanie L.; McGowan, Christine T.; Seitter, Samantha; Shindorf, Mackenzie L.; Parikh, Anup; Chatani, Praveen D.; Robbins, Paul F.; Rosenberg, Steven A.
Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer

干细胞样CD8 T细胞介导过继细胞免疫治疗对人类癌症的反应

Science
IF45.8
2020-01-010
OAAI
Sri Krishna; Frank J. Lowery; Amy R. Copeland; Erol Bahadiroglu; Ratnadeep Mukherjee; Li Jia; James Anibal; Abraham Sachs; Serifat O. Adebola; Devikala Gurusamy; Zhiya Yu; Victoria K. Hill; Jared J. Gartner; Yong F. Li; Maria R. Parkhurst; Biman C. Paria; Pia Kvistborg; Michael C. Kelly; Stephanie L. Goff; Grégoire Y Altan-Bonnet; Paul F. Robbins; Steven A. Rosenberg
Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers
CANCER DISCOVERY
IF33.3
2019-08-01207
OAAI
Parkhurst, Maria R.; Robbins, Paul F.; Tran, Eric; Prickett, Todd D.; Gartner, Jared J.; Jia, Li; Ivey, Gabriel; Li, Yong F.; El-Gamil, Mona; Lalani, Almin; Crystal, Jessica S.; Sachs, Abraham; Groh, Eric; Ray, Satyajit; Ngo, Lien T.; Kivitz, Scott; Pasetto, Anna; Yossef, Rami; Lowery, Frank J.; Goff, Stephanie L.; Lo, Winifred; Cafri, Gal; Deniger, Drew C.; Malekzadeh, Parisa; Ahmadzadeh, Mojgan; Wunderlich, John R.; Somerville, Robert P. T.; Rosenberg, Steven A.

研究方向

暂未获取到该数据
Dihua Yu 封面图
Dihua Yu
H 指数:85论文数:553被引数:2.9万
S
Steven A. Rosenberg
H 指数:219论文数:1,556被引数:19.6万
P
Paul F. Robbins
H 指数:91论文数:314被引数:4.3万
J
Jared J. Gartner
H 指数:42论文数:230被引数:1.2万
M
Maria R. Parkhurst
H 指数:44论文数:166被引数:1.3万
S
Sri Krishna
H 指数:23论文数:109被引数:2,997
S
Stephanie L. Goff
H 指数:32论文数:201被引数:6,622
S
Satyajit Ray
H 指数:29论文数:139被引数:5,138
T
Todd D. Prickett
H 指数:40论文数:199被引数:9,548
N
Noam Levin
H 指数:11论文数:41被引数:1,293