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J

Jack Bartram

Great Ormond Street Hospital
H指数:26
被引数:3,002

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Rapid Whole Genome Sequencing Enhances Pediatric Cancer Diagnosis

快速全基因组测序增强儿科癌症诊断

Nature Communications
IF15.7
2026-10-060
OAAI
Aditi Vedi; Jamie Trotman; Joao M. L. Dias; Martina Mijuskovic; Sera Choi; Laura Kingham; Rachel A. Moore; Sarah M. Leiter; Rowena Guermech; Amanda Semerene; Aviva Grisby; Sophie Wool; Victoria Joslin; Arunthethy Mahendrayogam; Jonathan Abrams; Michael Gattens; Esther Blanco; Emmy L. Dickens; Charlotte Burns; Matthew J. Murray; John A. Tadross; Claire Trayers; Catherine E. Hook; Jennifer Becq; Taksina Newington; Ivana Armogida; Zoya Kingsbury; Pascal Grobecker; Ines Vitoriano; Mitchell A. Bekritsky; Jacqueline Weir; Louise J. Fraser; Mark Ross; David Bentley; Matthew Cullen; Sam Behjati; Jack Bartram; Sean J. Humphray; Patrick Tarpey; David Rowitch
A phase 1 feasibility trial of BE-CAR33, an “off-the-shelf” base-edited CAR33 T cell therapy for acute myeloid leukemia

BE-CAR33的“现成”碱基编辑CAR33 T细胞疗法治疗急性髓性白血病的1期可行性试验

Science Translational Medicine
IF14.6
2026-08-190
PRE
Christos Georgiadis; Robert Chiesa; Hebatalla Rashed; Bethany K. Hughes; Roland Preece; Oliver Gough; Danielle Pinner; Stuart Adams; Rebecca Thomas; Annie Etuk; Avijeet Mishra; Hong Zhan; Toni Braybrook; Kimberly Gilmour; Victoria Potter; Jack Bartram; Phillip Ancliff; Martin Sauer; Waseem Qasim;
Single cell transcriptional evolution of myeloid leukemia of Down syndrome

唐氏综合征髓系白血病的单细胞转录演化

Nature Communications
IF15.7
2026-04-230
OAAI
Mi K. Trinh; Konstantin Schuschel; Hasan Issa; Rebecca Thomas; Conor Parks; Agnes Oszlanczi; Toochi Ogbonnah; Di Zhou; Lira Mamanova; Elena Prigmore; Emilia R. Robertson; Angus Hodder; Anna Wenger; Nathaniel D. Anderson; Holly J. Whitfield; Taryn D. Treger; José Gonçalves-Dias; Karin Straathof; David O’Connor; Matthew D. Young; Laura Jardine; Stuart Adams; Jan-Henning Klusmann; Jack Bartram; Sam Behjati
A non-canonical lymphoblast in refractory childhood T-cell leukaemia

难治性儿童T细胞白血病中的非典型淋巴母细胞

Nature Communications
IF15.7
2025-11-120
OAAI
Bram S. J. Lim; Holly J. Whitfield; Mi K. Trinh; Gianna Bloye; Rebecca Thomas; Nathaniel D. Anderson; Anna Wenger; Angus Hodder; Taryn D. Treger; Henry Lee-Six; Tim H. H. Coorens; Conor Parks; Toochi Ogbonnah; Petri Pölönen; Charles G. Mullighan; David T. Teachey; Jason Xu; Kai Tan; Melanie Hagleitner; Lennart Kester; Frank N. van Leeuwen; Gordon Beattie; Marc R. Mansour; Owen Williams; Jack Bartram; Stuart Adams; Laura Jardine; Sam Behjati; David O’Connor
Off-the-shelf dual CAR-iNKT cell immunotherapy eradicates medullary and leptomeningeal high-risk KMT2A-rearranged leukemia

现成的双CAR-iNKT细胞免疫疗法可清除髓内和软脑膜高风险KMT2A重排白血病

Blood
IF23.1
2025-09-040
OAAI
Hongwei Ren; Natalina Elliott; Bryan Lye; Mohammad Umer Sharif Shohan; Joe W. Cross; Lucy Field; Kanagaraju Ponnusamy; Siobhan Rice; Thomas Jackson; Ilia Leontari; Nouhad El Ouazzani; Rebecca Thomas; Sarah Inglott; Jack Bartram; Owen Smith; Jonathan Bond; Irene A. G. Roberts; Christina Halsey; Rachael Bashford-Rogers; Thomas A. Milne; Anindita Roy; Anastasios Karadimitris
PROM1/CD133 MARKS A PROLIFERATIVE STEM CELL LIKE POPULATION OF BLASTS IN KMT2A REARRANGED INFANT ALL

PROM1/CD133标记了KMT2A重排婴儿急性淋巴细胞白血病中的一种增殖性类干细胞blast群体。

Blood Advances
IF7.1
2025-07-050
OAAI
Joe Wilson Cross; Lucy Field; Alastair Smith; Emily Neil; Lucy Hamer; Thomas Jackson; Natalina Elliott; Siobhan Rice; Nicholas Crump; Joe Harman; Rebecca E. Ling; Qingqing Wu; Nouhad El Ouazzani; Rebecca Thomas; Sarah Inglott; Jack Bartram; Owen Smith; Jonathan Bond; Irene Roberts; Thomas A. Milne; Anindita Roy
Blinatumomab with De-Escalated Chemotherapy for Infant KMT2A-Rearranged B-Cell Acute Lymphoblastic Leukemia

Blinatumomab联合降阶梯化疗治疗婴儿KMT2A重排B细胞急性淋巴细胞白血病

BLOOD
IF23.1
2024-11-052
PRE
Hodder, Angus; Mishra, Avijeet Kumar; Connor, Philip; Cummins, Michelle; Cheng, Danny; Gattens, Michael; Gibson, Brenda; Ingham, Danielle; Lindsay, Katherine; Malone, Andrea; Madni, Majid; Moppett, John; Motwani, Jayashree; Patel, Pritesh; Ramanathan, Subramaniam; Roy, Anindita; James, Beki; Ancliff, Phil; Vora, Ajay; Bartram, Jack
A Non-Canonical Lymphoblast in Refractory Childhood T-Cell Acute Lymphoblastic Leukemia

难治性儿童T细胞急性淋巴细胞白血病中的非经典淋巴细胞 blasts

BLOOD
IF23.1
2024-11-050
PRE
Lim, Bram S. J.; Whitfield, Holly J.; Trinh, Mi K.; Bloye, Gianna; Thomas, Rebecca; Anderson, Nathaniel D.; Wenger, Anna; Hodder, Angus; Treger, Taryn D.; Lee-Six, Henry; Coorens, Tim H. H.; Parks, Conor; Ogbonnah, Toochi; Polonen, Petri; Mullighan, Charles G.; Teachey, David T.; Hagleitner, Melanie M.; Kester, Lennart A.; van Leeuwen, Frank N.; Beattie, Gordon; Mansour, Marc R.; Williams, Owen; Bartram, Jack; Adams, Stuart; Jardine, Laura; Behjati, Sam; O'Connor, David
Single Cell Multimodal Framework Identifies CD84 As a Leukaemic Stem Cell Target in Paediatric AML

单细胞多模态框架将CD84鉴定为儿童AML中的白血病干细胞靶点

BLOOD
IF23.1
2024-11-050
PRE
Espuelas, Macarena Oporto; Kanannejad, Sina; Michelozzi, Ilaria Marina; Castaneda, Eduardo Gomez; Xenakis, Theodoros; Kirtsios, Efstratios; Macpherson, Hannah; Bartram, Jack; Thomas, Rebecca; Giacopuzzi, Edoardo; Chatterjee, Soumick; Martignano, Filippo; Castellano, Sergi; Amrolia, Persis Jal; Giustacchini, Alice
Somatic genetic development of Wilms tumor via normal kidneys in predisposed children

易感儿童通过正常肾脏进行Wilms肿瘤的体细胞遗传发育

CANCER RESEARCH
IF16.6
2024-09-050
PRE
Treger, Taryn D.; Wegert, Jenny; Wenger, Anna; Coorens, Tim H. H.; Al-Saadi, Reem; Kemps, Paul; Kennedy, Jonathan; Parks, Conor; Anderson, Nathaniel D.; Hodder, Angus; Letunovska, Aleksandra; Jung, Hyunchul; Ogbonnah, Toochi; Mi Trinh; Lee-Six, Henry; Morcrette, Guillaume; van den Heuvel-Eibrink, Marry M.; Drost, Jarno; van Boxtel, Ruben; Bertrums, Eline; Goemans, Bianca; Jongmans, Marjolein; Kuiper, Roland; Antoniou, Evangelia; Reinhardt, Dirk; Bartram, Jack; Hutchinson, Ciaran; Vujanic, Gordan; Vokuhl, Christian; Chowdhury, Tanzina; Furtwangler, Rhoikos; Graf, Norbert; Gessler, Manfred; Behjati, Sam
Whole genome sequencing can reproduce all standard-of-care diagnostics for childhood cancer: Results from two national systems
CANCER RESEARCH
IF16.6
2024-09-050
PRE
Kennedy, Jonathan; Leiter, Sarah M.; Hodder, Angus; Kan, Sheng-Yuan; Bartram, Jack; Barone, Giuseppe; Gattens, Michael; Murray, Matthew J.; Behjati, Sam; Tarpey, Patrick; Cullen, Matthew; Ceraulo, Antony; Langenberg, Karin; Molenaar, Jan; Wessman, Sandra; Abel, Frida; Ljungman, Gustaf; Giraud, Geraldine; Blomstrand, Hakon Anderson; Rohan, Zdenek; Staffas, Anna; Orsmark-Pietras, Christina; Pandzic, Tatjana; Golovleva, Irina; Fogelstrand, Linda; Abrahamsson, Jonas; Noren-Nystrom, Ulrika; Palle, Josefine; Fioretos, Thoas; Franco, Lucia Cavelier; Barbany, Gisela; Corradini, Nadege; Schleirmacher, Gudrun; Rosenquist, Richard; Gisselsson, David; Vedi, Aditi
Whole genome sequencing provides practice-changing benefits when performed on consecutive, unselected children with suspected cancer
CANCER RESEARCH
IF16.6
2024-09-050
PRE
Hodder, Angus; Leiter, Sarah M.; Kennedy, Jonathan; Addy, Dilys; Ahmed, Munaza; Ajithkumar, Thankamma; Allinson, Kieren; Ancliff, Phil; Bailey, Shivani; Barnard, Gemma; Burke, G. A. Amos; Burns, Charlotte; Cano-Flanagan, Julian; Chalker, Jane; Coleman, Nicholas; Cheng, Danny; Clinch, Yasmin; Dryden, Caryl; Ghorashian, Sara; Griffin, Blanche; Horan, Gail; Hubank, Michael; May, Phillippa; McDerra, Joanna; Nagrecha, Rajvi; Nicholson, James; O'Connor, David; Pavasovic, Vesna; Quaegebeur, Annelies; Rao, Anupama; Roberts, Thomas; Samarasinghe, Sujith; Stasevich, Iryna; Tadross, John A.; Trayers, Claire; Trotman, Jamie; Vora, Ajay; Watkins, James; Chitty, Lyn S.; Bowdin, Sarah; Armstrong, Ruth; Murray, Matthew J.; Hook, Catherine E.; Tarpey, Patrick; Vedi, Aditi; Bartram, Jack; Behjati, Sam
Benefits for children with suspected cancer from routine whole-genome sequencing
NATURE MEDICINE
IF50
2024-07-025
OAAI
Hodder, Angus; Leiter, Sarah M.; Kennedy, Jonathan; Addy, Dilys; Ahmed, Munaza; Ajithkumar, Thankamma; Allinson, Kieren; Ancliff, Phil; Bailey, Shivani; Barnard, Gemma; Burke, G. A. Amos; Burns, Charlotte; Cano-Flanagan, Julian; Chalker, Jane; Coleman, Nicholas; Cheng, Danny; Clinch, Yasmin; Dryden, Caryl; Ghorashian, Sara; Griffin, Blanche; Horan, Gail; Hubank, Michael; May, Phillippa; McDerra, Joanna; Nagrecha, Rajvi; Nicholson, James; O'Connor, David; Pavasovic, Vesna; Quaegebeur, Annelies; Rao, Anupama; Roberts, Thomas; Samarasinghe, Sujith; Stasevich, Iryna; Tadross, John A.; Trayers, Claire; Trotman, Jamie; Vora, Ajay; Watkins, James; Chitty, Lyn S.; Bowdin, Sarah; Armstrong, Ruth; Murray, Matthew J.; Hook, Catherine E.; Tarpey, Patrick; Vedi, Aditi; Bartram, Jack; Behjati, Sam
Maintenance therapy for early loss of B-cell aplasia after anti-CD19 CAR T-cell therapy
BLOOD ADVANCES
IF7.1
2024-04-155
OAAI
Gabelli, Maria; Oporto-Espuelas, Macarena; Burridge, Saskia; Chu, Jan; Farish, Susan; Hedges, Emma; Ware, Kirsty; Williams, Lindsey; Young, Lindsey; Alajangi, Rajesh; Ancliff, Philip; Bartram, Jack; Bonney, Denise; Chenchara, Lenka; Chiesa, Robert; Cugno, Chiara; Hodby, Katharine; Jalowiec, Katarzyna A.; Lazareva, Arina; Lucchini, Giovanna; Mirci-Danicar, Oana C.; Mullanfiroze, Khushnuma; Pavasovic, Vesna; Rao, Anupama; Rao, Kanchan; Riley, Lynne; Samarasinghe, Sujith; Shenton, Geoff; Silva, Juliana; Vora, Ajay; Hough, Rachael; Amrolia, Persis J.; Ghorashian, Sara
Intention-to-treat outcomes utilising a stringent event definition in children and young people treated with tisagenlecleucel for r/r ALL through a national access scheme
BLOOD CANCER JOURNAL
IF11.6
2024-04-150
OAAI
Espuelas, Macarena Oporto; Burridge, Saskia; Kirkwood, Amy A.; Bonney, Denise; Watts, Kelly; Shenton, Geoff; Jalowiec, Katarzyna A.; O'Reilly, Maeve A.; Roddie, Claire; Castleton, Anna; Clesham, Katherine; Nicholson, Emma; Alajangi, Rajesh; Prabhu, Shilpa; George, Lindsay; Uttenthal, Ben; Gabelli, Maria; Neill, Lorna; Besley, Caroline; Chaganti, Sridhar; Wynn, Robert F.; Bartram, Jack; Chiesa, Robert; Lucchini, Giovanna; Pavasovic, Vesna; Rao, Anupama; Rao, Kanchan; Silva, Juliana; Samarasinghe, Sujith; Vora, Ajay; Clark, Peter; Cummins, Michelle; Marks, David I.; Amrolia, Persis; Hough, Rachael; Ghorashian, Sara

研究方向

暂未获取到该数据
S
Sam Behjati
H 指数:70论文数:277被引数:4.2万
A
Angus Hodder
H 指数:5论文数:35被引数:145
S
Stuart Adams
H 指数:35论文数:119被引数:7,664
S
Sarah Inglott
H 指数:19论文数:48被引数:2,997
S
Sujith Samarasinghe
H 指数:36论文数:133被引数:6,166
A
Ajay Vora
H 指数:66论文数:374被引数:1.7万
O
Owen Williams
H 指数:34论文数:164被引数:4,176
R
Rebecca Thomas
H 指数:11论文数:46被引数:719
D
David O’Connor
H 指数:23论文数:123被引数:2,234
M
Mi K. Trinh
H 指数:4论文数:30被引数:396