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D

David O'Connor

Great Ormond Street Hospital
H指数:23
被引数:2,234

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荣誉奖项

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Single cell transcriptional evolution of myeloid leukemia of Down syndrome

唐氏综合征髓系白血病的单细胞转录演化

Nature Communications
IF15.7
2026-04-230
OAAI
Mi K. Trinh; Konstantin Schuschel; Hasan Issa; Rebecca Thomas; Conor Parks; Agnes Oszlanczi; Toochi Ogbonnah; Di Zhou; Lira Mamanova; Elena Prigmore; Emilia R. Robertson; Angus Hodder; Anna Wenger; Nathaniel D. Anderson; Holly J. Whitfield; Taryn D. Treger; José Gonçalves-Dias; Karin Straathof; David O’Connor; Matthew D. Young; Laura Jardine; Stuart Adams; Jan-Henning Klusmann; Jack Bartram; Sam Behjati
EARLY RESPONSE AND GENETICS DEFINE RELAPSE RISK AFTER FRONTLINE BLINATUMOMAB IN CHILDHOOD B-ALL: A COHORT STUDY

早期反应和遗传学定义儿童B-ALL一线治疗布利塔尼单抗后的复发风险：一项队列研究

Blood Advances
IF7.1
2026-01-010
OA
Miguel Vieira Martins; Amir Enshaei; Yang Yang Wang; Jude Gibson; Jeremy P. Hancock; Stuart Paul Adams; Angus Hodder; Alison Spence; Andrea Malone; Andrew King; Anna Z. Castleton; Bethany Rose Mitchell; Christopher Dalley; Clare J. Rowntree; Danielle Ingham; David Devenney; Denise K. Bonney; Emma Nicholson; Galina Jigoulina; Ismail Elbeshlawi; Jayashree Motwani; Kaljit S. Bhuller; Katharine Patrick; Katherine Clesham; Katharine A. Hodby; Katherine Lindsay; Lindsay George; Majid Madni; Michael Gattens; Philip Connor; Sanjay Tewari; Subramaniam Ramanathan; Susan Baird; David O’Connor; Rachael Emma Hough; John P. Moppett; Ajay J Vora; Anthony V. Moorman; Sujith Samarasinghe
A non-canonical lymphoblast in refractory childhood T-cell leukaemia

难治性儿童T细胞白血病中的非典型淋巴母细胞

Nature Communications
IF15.7
2025-11-120
OAAI
Bram S. J. Lim; Holly J. Whitfield; Mi K. Trinh; Gianna Bloye; Rebecca Thomas; Nathaniel D. Anderson; Anna Wenger; Angus Hodder; Taryn D. Treger; Henry Lee-Six; Tim H. H. Coorens; Conor Parks; Toochi Ogbonnah; Petri Pölönen; Charles G. Mullighan; David T. Teachey; Jason Xu; Kai Tan; Melanie Hagleitner; Lennart Kester; Frank N. van Leeuwen; Gordon Beattie; Marc R. Mansour; Owen Williams; Jack Bartram; Stuart Adams; Laura Jardine; Sam Behjati; David O’Connor
British Society for Haematology updated guidelines for the diagnosis and management of tumour lysis syndrome in adults and children with haematological malignancies: A focus on patient safety

英国血液学学会更新了血液系统恶性肿瘤成人及儿童患者肿瘤溶解综合征的诊断与管理指南：聚焦患者安全

British Journal of Haematology
IF3.8
2025-09-030
OAAI
Y. L. Tracey Chan; Dima El-Sharkawi; Paras Shah; Dimitrios Chanouzas; David O'Connor; Stephen D. Marks; Gail Jones; the BSH Committee
Underlying biology, challenges and emergent concepts in the treatment of relapsed and refractory pediatric T-cell acute lymphoblastic leukemia

复发和难治性儿童T细胞急性淋巴细胞白血病的生物学基础、治疗挑战及新兴概念

Leukemia
IF13.4
2025-08-140
PRE
Patrícia Amaral; Rhona Christie; Daisy O. F. Gresham; Emma J. M. Lucas; Luyao Kevin Xu; Lena Behrmann; Jonathan Bond; Sofie Degerman; Frederik W. van Delft; Steven Goossens; Melanie Hagleitner; Chris Halsey; Nicholas Jones; Tim Lammens; Frank N. van Leeuwen; Marc R. Mansour; Panagiotis Ntziachristos; David O’Connor; João T. Barata
CREBBP inactivation sensitizes B cell acute lymphoblastic leukemia to ferroptotic cell death upon BCL2 inhibition

CREBBP失活会增强B细胞急性淋巴细胞白血病在BCL2抑制下的铁死亡敏感性。

NATURE COMMUNICATIONS
IF15.7
2025-05-200
OA
Garcia-Gimenez, Alicia; Ditcham, Jonathan E.; Azazi, Dhoyazan M. A.; Giotopoulos, George; Asby, Ryan; Meduri, Eshwar; Bagri, Jaana; Sakakini, Nathalie; Lopez, Cecile K.; Narayan, Nisha; Beinortas, Tumas; Agrawal-Singh, Shuchi; Fung, Kent; O'Connor, David; Mansour, Marc R.; Alabed, Husam B. R.; Jenkins, Benjamin; Koulman, Albert; Murphy, Michael P.; Horton, Sarah J.; Huntly, Brian J. P.
Preclinical development of anti-CD21 chimeric antigen receptor T cells to treat T cell acute lymphoblastic leukemia

抗CD21嵌合抗原受体T细胞治疗T细胞急性淋巴细胞白血病的临床前开发

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2025-04-160
PRE
Maciocia, Nicola; Hoekx, Malika; Acuna, Ciaran; Wade, Brandon; Burley, Amy; Ramanayake, Saumya; Nannini, Francesco; Wawrzyniecka, Patrycja A.; Karpanasamy, Thaneswari; Schuldt, Maria; Ng, Stephanie; Ferrari, Mathieu; Marafioti, Teresa; Gritti, Giuseppe; Onuoha, Shimobi; O'Connor, David; Lee, Lydia; Mansour, Marc; Khwaja, Asim; Pule, Martin; Maciocia, Paul
A Non-Canonical Lymphoblast in Refractory Childhood T-Cell Acute Lymphoblastic Leukemia

难治性儿童T细胞急性淋巴细胞白血病中的非经典淋巴细胞 blasts

BLOOD
IF23.1
2024-11-050
PRE
Lim, Bram S. J.; Whitfield, Holly J.; Trinh, Mi K.; Bloye, Gianna; Thomas, Rebecca; Anderson, Nathaniel D.; Wenger, Anna; Hodder, Angus; Treger, Taryn D.; Lee-Six, Henry; Coorens, Tim H. H.; Parks, Conor; Ogbonnah, Toochi; Polonen, Petri; Mullighan, Charles G.; Teachey, David T.; Hagleitner, Melanie M.; Kester, Lennart A.; van Leeuwen, Frank N.; Beattie, Gordon; Mansour, Marc R.; Williams, Owen; Bartram, Jack; Adams, Stuart; Jardine, Laura; Behjati, Sam; O'Connor, David
Whole genome sequencing provides practice-changing benefits when performed on consecutive, unselected children with suspected cancer
CANCER RESEARCH
IF16.6
2024-09-050
PRE
Hodder, Angus; Leiter, Sarah M.; Kennedy, Jonathan; Addy, Dilys; Ahmed, Munaza; Ajithkumar, Thankamma; Allinson, Kieren; Ancliff, Phil; Bailey, Shivani; Barnard, Gemma; Burke, G. A. Amos; Burns, Charlotte; Cano-Flanagan, Julian; Chalker, Jane; Coleman, Nicholas; Cheng, Danny; Clinch, Yasmin; Dryden, Caryl; Ghorashian, Sara; Griffin, Blanche; Horan, Gail; Hubank, Michael; May, Phillippa; McDerra, Joanna; Nagrecha, Rajvi; Nicholson, James; O'Connor, David; Pavasovic, Vesna; Quaegebeur, Annelies; Rao, Anupama; Roberts, Thomas; Samarasinghe, Sujith; Stasevich, Iryna; Tadross, John A.; Trayers, Claire; Trotman, Jamie; Vora, Ajay; Watkins, James; Chitty, Lyn S.; Bowdin, Sarah; Armstrong, Ruth; Murray, Matthew J.; Hook, Catherine E.; Tarpey, Patrick; Vedi, Aditi; Bartram, Jack; Behjati, Sam
Benefits for children with suspected cancer from routine whole-genome sequencing
NATURE MEDICINE
IF50
2024-07-025
OAAI
Hodder, Angus; Leiter, Sarah M.; Kennedy, Jonathan; Addy, Dilys; Ahmed, Munaza; Ajithkumar, Thankamma; Allinson, Kieren; Ancliff, Phil; Bailey, Shivani; Barnard, Gemma; Burke, G. A. Amos; Burns, Charlotte; Cano-Flanagan, Julian; Chalker, Jane; Coleman, Nicholas; Cheng, Danny; Clinch, Yasmin; Dryden, Caryl; Ghorashian, Sara; Griffin, Blanche; Horan, Gail; Hubank, Michael; May, Phillippa; McDerra, Joanna; Nagrecha, Rajvi; Nicholson, James; O'Connor, David; Pavasovic, Vesna; Quaegebeur, Annelies; Rao, Anupama; Roberts, Thomas; Samarasinghe, Sujith; Stasevich, Iryna; Tadross, John A.; Trayers, Claire; Trotman, Jamie; Vora, Ajay; Watkins, James; Chitty, Lyn S.; Bowdin, Sarah; Armstrong, Ruth; Murray, Matthew J.; Hook, Catherine E.; Tarpey, Patrick; Vedi, Aditi; Bartram, Jack; Behjati, Sam
Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2012-10-08128
OAAI
Roy, Anindita; Cowan, Gillian; Mead, Adam J.; Filippi, Sarah; Bohn, Georg; Chaidos, Aristeidis; Tunstall, Oliver; Chan, Jerry K. Y.; Choolani, Mahesh; Bennett, Phillip; Kumar, Sailesh; Atkinson, Deborah; Wyatt-Ashmead, Josephine; Hu, Ming; Stumpf, Michael P. H.; Goudevenou, Katerina; O'Connor, David; Chou, Stella T.; Weiss, Mitchell J.; Karadimitris, Anastasios; Jacobsen, Sten Eirik; Vyas, Paresh; Roberts, Irene

研究方向

暂未获取到该数据
J
Jack Bartram
H 指数:26论文数:141被引数:3,002
A
Angus Hodder
H 指数:5论文数:35被引数:145
S
Sam Behjati
H 指数:70论文数:277被引数:4.2万
M
Marc R. Mansour
H 指数:37论文数:217被引数:7,041
A
Ajay Vora
H 指数:66论文数:374被引数:1.7万
S
Stuart Adams
H 指数:35论文数:119被引数:7,663
L
Laura Jardine
H 指数:27论文数:85被引数:8,695
N
Nathaniel D. Anderson
H 指数:16论文数:97被引数:1,096
F
Frank N. van Leeuwen
H 指数:51论文数:210被引数:1.0万
M
Mi K. Trinh
H 指数:4论文数:30被引数:396