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G

Gillian L. Hirst

University of California, San Francisco
H指数:29
被引数:5,591

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Biomarker-guided responses in patient-derived organoids predict effective therapies in breast cancer

患者来源类器官中的生物标志物指导反应可预测乳腺癌的有效疗法

Cell Reports Medicine
IF10.6
2026-08-060
OAAI
Tam Binh V. Bui; Denise M. Wolf; Michael C. Bruck; Kaitlin Moore; Jessica Lien; Sarah D.W. Choi; Shruti Warhadpande; Amirabbas Parizadeh; Deborah Dillon; Beth Overmoyer; Filipa Lynce; Lamorna Brown-Swigart; Gillian L. Hirst; Christina Yau; Isaac J. Nijman; Boudewijn M.T. Burgering; Isaac S. Harris; Laura J. Esserman; Laura J. van ‘t Veer; Jennifer M. Rosenbluth
Peripheral blood transcriptional profiling predicts tumor subtype and neoadjuvant chemoimmunotherapy outcomes in human breast cancer

外周血转录组分析预测人乳腺癌的肿瘤亚型及新辅助化免治疗效果

Science Translational Medicine
IF14.6
2026-04-220
PRE
Xiaopeng Sun; Andres A. Ocampo; Ann Hanna; Brandie C. Taylor; Jacey L. Marshall; Julia A. Steele; Margaret L. Axelrod; Elizabeth C. Wescott; Susan R. Opalenik; Angela DeMichele; Laura J. Esserman; Minetta C. Liu; Rita Nanda; Denise M. Wolf; Lamorna Brown Swigart; Gillian L. Hirst; Laura J. van ‘t Veer; Yaomin Xu; Justin M. Balko
Circulating tumor DNA refines risk stratification of neoadjuvant therapy-resistant breast tumors

循环肿瘤DNA细化新辅助治疗耐药乳腺肿瘤的危险分层

Nature Communications
IF15.7
2025-12-090
OAAI
Mark Jesus M. Magbanua; Nayelis A. Manon; Denise M. Wolf; Samuel Rivero-Hinojosa; Ziad Ahmed; Rosalyn W. Sayaman; Antony Tin; Derrick Renner; Ekaterina Kalashnikova; Lamorna Brown-Swigart; Gillian L. Hirst; Christina Yau; Wen Li; Claudine Isaacs; Rebecca A. Shatsky; Amy S. Clark; Alexandra Zimmer; Amy L. Delson; Angel Rodriguez; Minetta C. Liu; Paula R. Pohlmann; Laura J. Esserman; Hope S. Rugo; Angela DeMichele; Laura van ‘t Veer
Pathologic complete response (pCR) rates for patients with HRD/HER2L high-risk, early-stage breast cancer (EBC) by clinical and molecular features in the phase II I-SPY2 clinical trial

在I-SPY2临床试验中，根据临床和分子特征，HRD/HER2L高风险早期乳腺癌（EBC）患者的病理完全缓解（pCR）率。

ANNALS OF ONCOLOGY
IF65.4
2025-02-012
PRE
Huppert, L. A.; Wolf, D.; Yau, C.; Brown-Swigart, L.; Hirst, G. L.; Isaacs, C.; Pusztai, L.; Pohlmann, P. R.; Demichele, A.; Shatsky, R.; Yee, D.; Thomas, A.; Nanda, R.; Perlmutter, J.; Heditsian, D.; Hylton, N.; Symmans, F.; van't Veer, L. J.; Esserman, L.; Rugo, H. S.
Intratumoral Injection of mRNA-2752 and Pembrolizumab for High-Risk Ductal Carcinoma In Situ A Phase 1 Nonrandomized Clinical Trial

mRNA-2752和Pembrolizumab瘤内注射治疗高危导管原位癌：一项1期非随机临床试验

JAMA ONCOLOGY
IF20.1
2025-01-161
PRE
Ramalingam, Kirithiga; Woody, Rachel; Glencer, Alexa; Schwartz, Christopher J.; Mori, Hidetoshi; Wong, Jasmine; Hirst, Gillian; Rosenbluth, Jennifer; Onishi, Natsuko; Gibbs, Jessica; Hylton, Nola; Borowsky, Alexander D.; Campbell, Michael; Esserman, Laura J.
Multi-platform biomarkers of response to an immune checkpoint inhibitor in the neoadjuvant I-SPY 2 trial for early-stage breast cancer
CELL REPORTS MEDICINE
IF10.6
2024-11-010
OAAI
Campbell, Michael J.; Wolf, Denise M.; Yau, Christina; Brown-Swigart, Lamorna; Wulfkuhle, Julie; Gallagher, Isela R.; Zhu, Zelos; Bolen, Jennifer; Vandenberg, Scott; Hoyt, Clifford; Mori, Hidetoshi; Borowsky, Alexander; Sit, Laura; Perlmutter, Jane; Asare, Smita M.; Nanda, Rita; Liu, Minetta C.; Yee, Douglas; Demichele, Angela M.; Hylton, Nola M.; Pusztai, Lajos; Berry, Donald A.; Hirst, Gillian L.; Petricoin, Emanuel F.; van't Veer, Laura; Esserman, Laura
Regional lymph node changes on breast MRI in patients with early-stage breast cancer receiving neoadjuvant chemo-immunotherapy

接受新辅助化免疫治疗的早期乳腺癌患者乳腺MRI上区域淋巴结的改变

BREAST CANCER RESEARCH AND TREATMENT
IF3
2024-09-210
OAAI
Jacob, Saya; Christofferson, Anika; Fisch, Samantha; Norwood, Peter; Castillo, Paolo; Yu, Hongmei; Hirst, Gillian; Soliman, Hatem; Nanda, Rita; Mukhtar, Rita A.; Ewing, Cheryl; Majure, Melanie; Melisko, Michelle; Rugo, Hope S.; Esserman, Laura; Price, Elissa; Chien, A. Jo
Datopotamab-deruxtecan in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial

Datopotamab-deruxtecan治疗早期乳腺癌: 序贯多重分配随机I-SPY2.2 2期试验

NATURE MEDICINE
IF50
2024-09-141
PRE
Khoury, Katia; Meisel, Jane L.; Yau, Christina; Rugo, Hope S.; Nanda, Rita; Davidian, Marie; Tsiatis, Butch; Chien, A. Jo; Wallace, Anne M.; Arora, Mili; Rozenblit, Mariya; Hershman, Dawn L.; Zimmer, Alexandra; Clark, Amy S.; Beckwith, Heather; Elias, Anthony D.; Stringer-Reasor, Erica; Boughey, Judy C.; Nangia, Chaitali; Vaklavas, Christos; Omene, Coral; Albain, Kathy S.; Kalinsky, Kevin M.; Isaacs, Claudine; Tseng, Jennifer; Torres, Evanthia T. Roussos; Thomas, Brittani; Thomas, Alexandra; Sanford, Amy; Balassanian, Ronald; Ewing, Cheryl; Yeung, Kay; Sauder, Candice; Sanft, Tara; Pusztai, Lajos; Trivedi, Meghna S.; Outhaythip, Ashton; Li, Wen; Onishi, Natsuko; Asare, Adam L.; Beineke, Philip; Norwood, Peter; Brown-Swigart, Lamorna; Hirst, Gillian L.; Matthews, Jeffrey B.; Moore, Brian; Symmans, W. Fraser; Price, Elissa; Beedle, Carolyn; Perlmutter, Jane; Pohlmann, Paula; Shatsky, Rebecca A.; Demichele, Angela; Yee, Douglas; van't Veer, Laura J.; Hylton, Nola M.; Esserman, Laura J.
Datopotamab-deruxtecan plus durvalumab in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial

Datopotamab-deruxtecan联合durvalumab治疗早期乳腺癌: 序贯多重分配随机I-SPY2.2 2期试验

NATURE MEDICINE
IF50
2024-09-144
PRE
Shatsky, Rebecca A.; Trivedi, Meghna S.; Yau, Christina; Nanda, Rita; Rugo, Hope S.; Davidian, Marie; Tsiatis, Butch; Wallace, Anne M.; Chien, A. Jo; Stringer-Reasor, Erica; Boughey, Judy C.; Omene, Coral; Rozenblit, Mariya; Kalinsky, Kevin; Elias, Anthony D.; Vaklavas, Christos; Beckwith, Heather; Williams, Nicole; Arora, Mili; Nangia, Chaitali; Torres, Evanthia T. Roussos; Thomas, Brittani; Albain, Kathy S.; Clark, Amy S.; Falkson, Carla; Hershman, Dawn L.; Isaacs, Claudine; Thomas, Alexandra; Tseng, Jennifer; Sanford, Amy; Yeung, Kay; Boles, Sarah; Chen, Yunni Yi; Huppert, Laura; Jahan, Nusrat; Parker, Catherine; Giridhar, Karthik; Howard, Frederick M.; Blackwood, M. Michele; Sanft, Tara; Li, Wen; Onishi, Natsuko; Asare, Adam L.; Beineke, Philip; Norwood, Peter; Brown-Swigart, Lamorna; Hirst, Gillian L.; Matthews, Jeffrey B.; Moore, Brian; Symmans, W. Fraser; Price, Elissa; Heditsian, Diane; Lestage, Barbara; Perlmutter, Jane; Pohlmann, Paula; Demichele, Angela; Yee, Douglas; van 't Veer, Laura J.; Hylton, Nola M.; Esserman, Laura J.
The impact of changes in tumor mutational landscape during neoadjuvant therapy on tumor-informed ctDNA testing in breast cancer patients

新辅助治疗期间肿瘤突变谱变化对肿瘤信息ctDNA检测在乳腺癌患者中的影响

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Magbanua, M.; Rivero-Hinojosa, S.; Sayaman, R.; Tin, T.; Kalashnikova, E.; Wolf, D.; Brown-Swigart, L.; Hirst, G.; Yau, C.; Isaacs, C.; Shatsky, R. A.; Delson, A.; Palsuledesai, C. C.; Rodriguez, A. A.; Liu, M. C.; Pohlmann, P. R.; Esserman, L.; Rugo, H. S.; DeMichele, A.; Van't Veer, L. J.
Immune subtyping identifies a subset of HR+HER2-early-stage breast cancer patients with a very high likelihood of response to neoadjuvant immunotherapy (IO): Results from 5 IO arms of the I-SPY2 TRIAL
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Wolf, Denise M.; Yau, Christina; Pusztai, Lajos; Nanda, Rita; Chien, Jo; Stringer-Reasor, Erica; Shatsky, Rebecca; Isaacs, Claudine; Liu, MInetta; Han, Hyo; Soliman, Hatem; Campbell, Michael; Glas, Annuska; Barcaru, Andrei; Mittempergher, Lorenza; Kuilman, Midas; Swigart, Lamorna Brown; Hirst, Gillian; Yu, Hongmei; Beineke, Philip; Basu, Amrita; Yee, Douglas; Symmans, W. Fraser; DeMichele, Angela; Perlmutter, Jane; Delson, Amy; Huppert, Laura; Rugo, Hope; Clark, Amy; Hylton, Nola; Pohlmann, Paula; Esserman, Laura; van 't Veer, Laura
Cell-free DNA Concentration as a Biomarker of Response and Recurrence in HER2-Negative Breast Cancer Receiving Neoadjuvant Chemotherapy
CLINICAL CANCER RESEARCH
IF10.2
2024-03-120
PRE
Magbanua, Mark Jesus M.; Ahmed, Ziad; Sayaman, Rosalyn W.; Swigart, Lamorna Brown; Hirst, Gillian L.; Yau, Christina; Wolf, Denise M.; Li, Wen; Delson, Amy L.; Perlmutter, Jane; Pohlmann, Paula; Symmans, W. Fraser; Yee, Douglas; Hylton, Nola M.; Esserman, Laura J.; Demichele, Angela M.; Rugo, Hope S.; van't Veer, Laura J.
Heterogeneous cell populations in organoid models derived from breast preinvasive and invasive carcinomas after endocrine therapy
CANCER RESEARCH
IF16.6
2024-02-010
PRE
Goldhammer, Nadine; Warhadpande, Shruti; Beld, Liana; Rodas, Cristian K. Maldonado; Lam, Allison; Bui, Tam Binh; Abe, Shoko Emily; Alvarado, Michael; Ewing, Cheryl; Goodwin, Karen; Mukhtar, Rita; Wong, Jasmine; Swigart, Lamorna Brown; Hirst, Gillian; Schwartz, Christopher; van't Veer, Laura; Esserman, Laura; Chien, Jo; Rosenbluth, Jennifer M.

研究方向

暂未获取到该数据
C
Christina Yau
H 指数:92论文数:571被引数:7.9万
L
Laura J. Esserman
H 指数:89论文数:990被引数:3.3万
L
Lamorna Brown Swigart
H 指数:36论文数:290被引数:8,416
D
Denise M. Wolf
H 指数:44论文数:269被引数:2.6万
A
Angela DeMichele
H 指数:89论文数:736被引数:2.8万
D
Douglas Yee
H 指数:83论文数:583被引数:2.5万
L
Laura van ‘t Veer
H 指数:71论文数:513被引数:4.8万
N
Nola M. Hylton
H 指数:62论文数:375被引数:1.4万
R
Rita Nanda
H 指数:56论文数:548被引数:1.6万
C
Claudine Isaacs
H 指数:97论文数:751被引数:3.7万