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F

Florian Klein

University of Cologne

65H指数
383论文数
2.1W被引数
收录论文 136
发表时间
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A case of Bundibugyo virus disease treated with monoclonal antibodies and remdesivir使用单克隆抗体和瑞德西韦治疗的布桑加里病毒病病例
errNature Medicine
IF50
err2026-08-24
err0
errOAAI
errAlexander Uhrig; Frieder Pfäfflin; Pinkus Tober-Lau; Victor M. Corman; Miriam S. Stegemann; Paulina Tarnow; Monika Rottstegge; Katrin Moira Heim; Felix Bremer; Thomas Cronen; Tilman Lingscheid; Han Ngoc Le; Dominik Geus; Mary J. Choi; William A. Fischer; Wesley R. Campbell; Aneesh K. Mehta; Marylyn M. Addo; Placide Mbala-Kingebeni; David Hillus; Christian Gaebler; Stephan Becker; Janine Michel; Andreas Nitsche; Andreas Kurth; Martin Witzenrath; Till D. Best; Stephan Günther; Lisa Oestereich; Manuel Koch; Matthias Zehner; Henning Gruell; Christian Drosten; Florian Klein; Florian Kurth; Leif E. Sander
err分享
err收藏
Post-Exposure Prophylaxis with a monoclonal antibody cocktail Following Bundibugyo Ebolavirus Exposure in Adults and Children在 Bundibugyo 埃博拉病毒暴露后，成人和儿童使用单克隆抗体鸡尾酒进行暴露后预防
errNature Medicine
IF50
err2026-08-24
err0
errOAAI
errChristian Gaebler; Han Ngoc Le; Luise Martin; Paulina Tarnow; Alexander Gratopp; Stefanie Hort; Anke Wendt; Monika Rottstegge; Pinkus Tober Lau; Matthias Zehner; Henning Gruell; Manuel Koch; Victor Corman; Till Dominik Best; Shreeya Amatya; Mary J. Choi; William A. Fischer; Wesley R. Campbell; Aneesh K. Mehta; Marylyn M. Addo; Renate Krüger; Susanne Lau; Philip Bufler; Marcus A. Mall; Christian Drosten; Lisa Oestereich; Tilman Lingscheid; Katrin Moira Heim; Alexander Uhrig; Frieder Pfäfflin; Miriam S. Stegemann; Florian Klein; Florian Kurth; Leif Erik Sander
err分享
err收藏
ERBB2 signaling drives immune cell evasion and resistance against immunotherapy in small cell lung cancerERBB2信号驱动小细胞肺癌中的免疫细胞逃逸以及对免疫治疗的抵抗
errNature Communications
IF15.7
err2025-12-09
err0
errOAAI
errLydia Meder; Charlotte I. Orschel; Cyrielle L. Bouchez; Rahil Gholamipoorfard; Claudia V. Orschel; David Stahl; Christoph Kreer; Mirjam Koker; Marieke Nill; Ilayda G. Kocak; Ka-Won Noh; Xinlei Zhao; Leon Ullrich; Björn Häupl; Josefine Jakob; Marie-Lisa Eich; Alexandra Florin; Holger Grüll; Jürgen Wolf; Filippo Beleggia; Reinhard Büttner; Thomas Oellerich; Florian Klein; Johannes Brägelmann; H. Christian Reinhardt; Nima Abedpour; Roland T. Ullrich
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Sustained HIV-1 remission after heterozygous CCR5Δ32 stem cell transplantationCCR5Δ32杂合干细胞移植后的持续HIV-1缓解
errNature
IF48.5
err2025-12-01
err0
PREAI
errChristian Gaebler; Samad Kor; Kristina Allers; Michela Perotti; David Mwangi; Karolin Meixenberger; Kirsten Hanke; Timo Trenkner; Tom Kraus; Yequin Sha; Carmen Arentowicz; Stanley Odidika; Nikolai Grahn; Rachel Scheck; Naomi Perkins; Marion Pardons; Vanessa Igbokwe; Victor Corman; Thomas Burmeister; Olga Blau; Gülüstan Sürücü; Axel Pruß; Christian G. Schneider; Gerd Klausen; Jürgen Sauter; Florian Klein; Leif E. Sander; Jörg Hofmann; Lam Vuong; Lars Bullinger; Livius Penter; Henning Gruell; Daniel B. Reeves; Philipp Schommers; Angelique Hoelzemer; Martin Obermeier; Igor W. Blau; Thomas Schneider; Olaf Penack
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Profiling of HIV-1 elite neutralizer cohort reveals a CD4bs bnAb for HIV-1 prevention and therapyHIV-1精英中和者队列的表征分析揭示了一种靶向CD4bs的广谱中和抗体，可用于HIV-1的预防和治疗
errNature Immunology
IF27.6
err2025-10-06
err0
errOAAI
errLutz Gieselmann; Andrew T. DeLaitsch; Malena Rohde; Henning Gruell; Christoph Kreer; Meryem Seda Ercanoglu; Harry B. Gristick; Philipp Schommers; Elvin Ahmadov; Caelan Radford; Andrea Mazzolini; Lily Zhang; Anthony P. West; Johanna Worczinski; Anna Momot; Maren L. Reichwein; Jacqueline Knüfer; Ricarda Stumpf; Nonhlanhla N. Mkhize; Haajira Kaldine; Sinethemba Bhebhe; Sharvari Deshpande; Federico Giovannoni; Erin Stefanutti; Fabio Benigni; Colin Havenar-Daughton; Davide Corti; Arne Kroidl; Anurag Adhikari; Aubin J. Nanfack; Georgia E. Ambada; Ralf Duerr; Lucas Maganga; Wiston William; Nyanda E. Ntinginya; Timo Wolf; Christof Geldmacher; Michael Hoelscher; Clara Lehmann; Penny L. Moore; Thierry Mora; Aleksandra M. Walczak; Peter B. Gilbert; Nicole A. Doria-Rose; Yunda Huang; Jesse D. Bloom; Michael S. Seaman; Pamela J. Bjorkman; Florian Klein
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Guiding Antiviral Cell Therapy Approaches with an Online Resource of Clinically Scored Epitopes, T-Cell Receptors, and B-Cell Receptors通过临床评分表位、T细胞受体和B细胞受体的在线资源指导抗病毒细胞疗法研究
errTRANSFUSION MEDICINE AND HEMOTHERAPY
IF1.9
err2025-09-01
err0
errOAAI
errKaeuferle, Theresa; Eiz-Vesper, Britta; Moosmann, Andreas; Behrends, Uta; Decker, Michel; Gutjahr, Lilli; Mautner, Josef; Klein, Florian; Kreer, Christoph; Reger, Mira; Busch, Dirk H.; D'ippolito, Elvira; Kohlmayer, Florian; Menzel, Amrei; Willier, Semjon; Maecker-Kolhoff, Britta; Feuchtinger, Tobias
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err收藏
High rate of RNAemia and impaired immunity in patients with immunodeficiency in the vaccination era
errJOURNAL OF CLINICAL VIROLOGY
IF3.4
err2025-04-01
err0
errOAAI
errThierbach, Anne; Di Cristanziano, Veronica; Eberhardt, Kirsten A.; Pirkl, Martin; Steger, Gertrud; Heger, Eva; Kaiser, Rolf; Koch, Manuel; Klein, Florian; Rauschning, Dominic; Malin, Jakob J.
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err收藏
Human cytomegalovirus gH/gL/gO binding to PDGFRα provides a regulatory signal activating the fusion protein gB that can be blocked by neutralizing antibodies
errJOURNAL OF VIROLOGY
IF3.8
err2025-04-01
err0
errOAAI
errSchultz, Eric P.; Ponsness, Lars; Lanchy, Jean-Marc; Zehner, Matthias; Klein, Florian; Ryckman, Brent J.
err分享
err收藏
A human monoclonal antibody neutralizing SARS-CoV-2 Omicron variants containing the L452R mutation人单克隆抗体中和含有L452R突变的SARS-CoV-2 Omicron变体
errJOURNAL OF VIROLOGY
IF3.8
err2024-12-17
err4
errOAAI
errStein, Saskia C.; Hansen, Guido; Ssebyatika, George; Stroeh, Luisa J.; Ochulor, Okechukwu; Herold, Elisabeth; Schwarzloh, Britta; Mutschall, Doris; Zischke, Jasmin; Cordes, Anne K.; Schneider, Talia; Hinrichs, Imke; Blasczyk, Rainer; Kleine-Weber, Hannah; Hoffmann, Markus; Klein, Florian; Kaiser, Franziska K.; Gonzalez-Hernandez, Mariana; Armando, Federico; Ciurkiewicz, Malgorzata; Beythien, Georg; Poehlmann, Stefan; Baumgaertner, Wolfgang; Osterhaus, Albert; Schulz, Thomas F.; Krey, Thomas
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From Gut to Blood: Redistribution of Zonulin in People Living with HIV
errBIOMEDICINES
IF3.9
err2024-10-11
err0
errOAAI
errAugustin, Max; Horn, Carola; Ercanoglu, Meryem Seda; Bondet, Vincent; de Silva, Ute Sandaradura; Suarez, Isabelle; Chon, Seung-Hun; Nierhoff, Dirk; Zoufaly, Alexander; Wenisch, Christoph; Knops, Elena; Heger, Eva; Klein, Florian; Duffy, Darragh; Muller-Trutwin, Michaela; Lehmann, Clara
err分享
err收藏
Blocking the angiopoietin-2-dependent integrin β-1 signaling axis abrogates small cell lung cancer invasion and metastasis
errJCI INSIGHT
IF6.1
err2024-05-22
err1
errOAAI
errMeder, Lydia; Orschel, Charlotte Isabelle; Otto, Christoph Julius; Koker, Mirjam; Braegelmann, Johannes; Ercanoglu, Meryem S.; Daehling, Sabrina; Compes, Anik; Selenz, Carolin; Nill, Marieke; Dietlein, Felix; Florin, Alexandra; Eich, Marie -Lisa; Borchmann, Sven; Odenthal, Margarete; Blazquez, Raquel; Hilberg, Frank; Klein, Florian; Hallek, Michael; Buettner, Reinhard; Reinhardt, H. Christian; Ullrich, Roland T.
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err收藏
CARs derived from broadly neutralizing, human monoclonal antibodies identified by single B cell sorting target hepatitis B virus-positive cells
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-04-22
err2
errOAAI
errSchreiber, Sophia; Dressler, Lisa S.; Loffredo-Verde, Eva; Asen, Theresa; Faerber, Stephanie; Wang, Wenshi; Groll, Tanja; Chakraborty, Anindita; Kolbe, Fenna; Kreer, Christoph; Kosinska, Anna D.; Simon, Sylvain; Urban, Stephan; Klein, Florian; Riddell, Stanley R.; Protzer, Ulrike
err分享
err收藏
Semen enhances transmitted/founder HIV-1 infection and only marginally reduces antiviral activity of broadly neutralizing antibodies
errJOURNAL OF VIROLOGY
IF3.8
err2024-04-16
err0
errOAAI
errvon Maltitz, Pascal; Wettstein, Lukas; Weil, Tatjana; Schommers, Philipp; Klein, Florian; Muench, Jan
err分享
err收藏
SARS-CoV-2 Test-to-Stay in Daycare
errPEDIATRICS
IF6.4
err2024-04-10
err0
PREAI
errDewald, Felix; Steger, Gertrud; Fish, Irina; Torre-Lage, Ivonne; Hellriegel, Christina; Milz, Esther; Kolb-Bastigkeit, Anja; Heger, Eva; Fries, Mira; Buess, Michael; Marizy, Niklas; Michaelis, Barbara; Suarez, Isabelle; Rubio Quintanares, Gibran Horemheb; Pirkl, Martin; Aigner, Annette; Oberste, Max; Hellmich, Martin; Wong, Anabelle; Orduz, Juan Camilo; Faetkenheuer, Gerd; Doetsch, Joerg; Kossow, Annelene; Moench, Eva-Maria; Quade, Gustav; Neumann, Udo; Kaiser, Rolf; Schranz, Madlen; Klein, Florian
err分享
err收藏
Torque Teno Virus Load Is Associated With Centers for Disease Control and Prevention Stage and CD4+ Cell Count in People Living With Human Immunodeficiency Virus but Seems Unrelated to AIDS-Defining Events and Human Pegivirus Load
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2024-01-17
err5
errOAAI
errEsser, Pia L.; Quintanares, Gibran H. Rubio; Langhans, Bettina; Heger, Eva; Boehm, Michael; Jensen, Bjoern-Erik O. L. E.; Esser, Stefan; Luebke, Nadine; Faetkenheuer, Gerd; Lengauer, Thomas; Klein, Florian; Oette, Mark; Rockstroh, Juergen K.; Boesecke, Christoph; Di Cristanziano, Veronica; Kaiser, Rolf; Pirkl, Martin
err分享
err收藏
Lack of monkeypox virus (MPXV) transmission despite occupational exposure of a large number of health care workers
errJOURNAL OF MEDICAL VIROLOGY
IF4.6
err2024-01-04
err0
PREAI
errWetsch, Wolfgang A.; Heger, Eva; Drinhaus, Hendrik; Boettiger, Bernd W.; Overbeek, Remco; Lehmann, Clara; Faetkenheuer, Gerd; Jung, Norma; Fischer, Julia; Kneifel, Jens; Zweigner, Janine; Klein, Florian; Wieland, Ulrike
err分享
err收藏
LMP1 and EBNA2 constitute a minimal set of EBV genes for transformation of human B cellsLMP1和EBNA2构成了用于转化人b细胞的最小EBV基因集
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-12-19
err8
errOAAI
errZhang, Jingwei; Sommermann, Thomas; Li, Xun; Gieselmann, Lutz; de la Rosa, Kathrin; Stecklum, Maria; Klein, Florian; Kocks, Christine; Rajewsky, Klaus
err分享
err收藏
Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants
errIMMUNITY
IF26.3
err2023-12-01
err8
errOAAI
errKorenkov, Michael; Zehner, Matthias; Cohen-Dvashi, Hadas; Borenstein-Katz, Aliza; Kottege, Lisa; Janicki, Hanna; Vanshylla, Kanika; Weber, Timm; Gruell, Henning; Koch, Manuel; Diskin, Ron; Kreer, Christoph; Klein, Florian
err分享
err收藏
Enhanced SARS-CoV-2 humoral immunity following breakthrough infection builds upon the preexisting memory B cell pool
errSCIENCE IMMUNOLOGY
IF16.3
err2023-11-24
err10
PREAI
errWeber, Timm; Daehling, Sabrina; Rose, Svea; Affeldt, Patrick; Vanshylla, Kanika; Ullrich, Leon; Gieselmann, Lutz; Teipel, Finn; Gruell, Henning; Di Cristanziano, Veronica; Kim, Dae Sung; Georgiou, George; Koch, Manuel; Kreer, Christoph; Klein, Florian
err分享
err收藏
Dynamics and durability of HIV-1 neutralization are determined by viral replication
errNATURE MEDICINE
IF50
err2023-11-13
err2
errOAAI
errSchommers, Philipp; Kim, Dae Sung; Schlotz, Maike; Kreer, Christoph; Eggeling, Ralf; Hake, Anna; Stecher, Melanie; Park, Juyeon; Radford, Caelan E.; Dingens, Adam S.; Ercanoglu, Meryem S.; Gruell, Henning; Odidika, Stanley; Dahlhaus, Marten; Gieselmann, Lutz; Ahmadov, Elvin; Lawong, Rene Y.; Heger, Eva; Knops, Elena; Wyen, Christoph; Kuemmerle, Tim; Roemer, Katja; Scholten, Stefan; Wolf, Timo; Stephan, Christoph; Suarez, Isabelle; Raju, Nagarajan; Adhikari, Anurag; Esser, Stefan; Streeck, Hendrik; Duerr, Ralf; Nanfack, Aubin J.; Zolla-Pazner, Susan; Geldmacher, Christof; Geisenberger, Otto; Kroidl, Arne; William, Wiston; Maganga, Lucas; Ntinginya, Nyanda Elias; Georgiev, Ivelin S.; Vehreschild, Joerg J.; Hoelscher, Michael; Faetkenheuer, Gerd; Lavinder, Jason J.; Bloom, Jesse D.; Seaman, Michael S.; Lehmann, Clara; Pfeifer, Nico; Georgiou, George; Klein, Florian
err分享
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研究方向

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合作学者
合作期刊
M
Michel C. Nussenzweig
H 指数: 183 · 论文数: 618
I
Ian A. Wilson
H 指数: 179 · 论文数: 1.7K
D
Dennis R. Burton
H 指数: 172 · 论文数: 800
M
Michael P. Manns
H 指数: 163 · 论文数: 2.1K
B
Bruce D. Walker
H 指数: 160 · 论文数: 946
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