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收藏分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Brain-wide microglia replacement using a nonconditioning strategy ameliorates pathology in mouse models of neurological disorders采用非条件性策略的全脑小胶质细胞替换可改善神经疾病小鼠模型的病理学表现
Chen, Dadian; Wang, Chen; Chen, Xi; Li, Jiayu; Chen, Shuai; Li, Yanzhong; Ma, Fangling; Li, Tingting; Zou, Mengling; Li, Xin; Huang, Xiaohua; Zhang, Yun-wu; Zhao, Yingjun; Zheng, Honghua; Chen, Xiao-Fen; Zhong, Li 分享 收藏 Mdga2 deficiency leads to an aberrant activation of BDNF/TrkB signaling that underlies autism-relevant synaptic and behavioral changes in miceMdga2缺陷会导致BDNF/TrkB信号通路的异常激活，这构成了小鼠自闭症相关的突触和行为的改变的基础。Zhao, Dongdong; Huo, Yuanhui; Zheng, Naizhen; Zhu, Xiang; Yang, Dingting; Zhou, Yunqiang; Wang, Shengya; Jiang, Yiru; Wu, Yili; Zhang, Yun-wu 分享 收藏 Electrophysiology-based screening identifies neuronal HtrA serine peptidase 2 (HTRA2) as a synaptic plasticity regulator participating in tauopathyZheng, Naizhen; Li, Kun; Cao, Jing; Wang, Zijie; Zhang, Liang; Zhao, Zihao; He, Jiawei; Wang, Yong; Zhu, Xiang; Chen, Yiqing; Meng, Jian; Zhao, Dongdong; Niu, Mengxi; Luo, Hong; Zhang, Xian; Sun, Hao; Zhang, Yun-wu 分享 收藏 Microglial CD2AP deficiency exerts protection in an Alzheimer's disease model of amyloidosis小胶质细胞CD2AP缺陷在淀粉样变性的阿尔茨海默病模型中发挥保护作用Zhang, Lingliang; Huang, Lingling; Zhou, Yuhang; Meng, Jian; Zhang, Liang; Zhou, Yunqiang; Zheng, Naizhen; Guo, Tiantian; Zhao, Shanshan; Wang, Zijie; Huo, Yuanhui; Zhao, Yingjun; Chen, Xiao-fen; Zheng, Honghua; Holtzman, David M.; Zhang, Yun-wu 分享 收藏 Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis (vol 87, pg 963, 2015)Zhao, Yingjun; Tseng, I. -Chu; Heyser, Charles J.; Rockenstein, Edward; Mante, Michael; Adame, Anthony; Zheng, Qiuyang; Huang, Timothy; Wang, Xin; Arslan, Pharhad E.; Chakrabarty, Paramita; Wu, Chengbiao; Bu, Guojun; Mobley, William C.; Zhang, Yun-wu; St George-Hyslop, Peter; Masliah, Eliezer; Fraser, Paul; Xu, Huaxi 分享 收藏 Evaluation of Soluble Colony Stimulating Factor 1 Receptor (CSF1R) in Peripheral Blood as a Diagnostic Marker of CSF1R-Related Disorder (CSF1R-RD) in a Murine Model and CSF1R-RD PatientsHu, Banglian; Zhou, Yuhang; Wu, Chujun; Xiao, Naian; Li, Jianpeng; Li, Xin; Li, Yanfang; Zhang, Xian; Huang, Xiaohua; Song, Yabin; Wang, Zhanxiang; Zhang, Yun-Wu; Zhang, Zaiqiang; Zheng, Honghua 分享 收藏 CD2AP promotes the progression of glioblastoma multiforme via TRIM5-mediated NF-kB signalingCD2AP通过TRIM5-mediated nf-kb信号促进多形性胶质母细胞瘤的进展Zhang, Liang; He, Jiawei; Zhao, Wentao; Zhou, Yuhang; Li, Jin; Li, Shaobo; Zhao, Wenpeng; Zhang, Lingliang; Tang, Ziqian; Tan, Guowei; Chen, Sifang; Zhang, Bingchang; Zhang, Yun-wu; Wang, Zhanxiang 分享 收藏 分享 收藏 P-tau217 correlates with neurodegeneration in Alzheimer's disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathyZhang, Denghong; Zhang, Wei; Ming, Chen; Gao, Xuheng; Yuan, Huilong; Lin, Xiaojie; Mao, Xinru; Wang, Chunping; Guo, Xiaoyi; Du, Ying; Shao, Lin; Yang, Renzhi; Lin, Zhihao; Wu, Xilin; Huang, Timothy Y.; Wang, Zhanxiang; Zhang, Yun-wu; Xu, Huaxi; Zhao, Yingjun 分享 收藏 分享 收藏 分享 收藏 Tau reduction attenuates autism-like features in Fmr1 knockout miceZhao, Shanshan; Jiang, Xiangyu; Han, Linkun; Jiang, Yiru; Wang, Yong; Meng, Jian; Zhu, Xiang; Zhang, Xian; Luo, Hong; Zhang, Yun-wu 分享 收藏 Microglial repopulation reverses cognitive and synaptic deficits in an Alzheimer's disease model by restoring BDNF signalingWang, Wanbing; Li, Yanzhong; Ma, Fangling; Sheng, Xuan; Chen, Kai; Zhuo, Rengong; Wang, Chen; Zheng, Honghua; Zhang, Yun-wu; Bu, Guojun; Chen, Xiao-Fen; Zhong, Li 分享 收藏 TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegenerationZhong, Li; Sheng, Xuan; Wang, Wanbing; Li, Yanzhong; Zhuo, Rengong; Wang, Kai; Zhang, Lianshuai; Hu, Dan-Dan; Hong, Yujuan; Chen, Linting; Rao, Hengjun; Li, Tingting; Chen, Muyang; Lin, Zhihao; Zhang, Yun-wu; Wang, Xin; Yan, Xiao-Xin; Chen, Xiaochun; Bu, Guojun; Chen, Xiao-Fen 分享 收藏 
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