Bi‐Sen Ding - Publications, H-index & Citations

丁楅森 (Bi‐Sen Ding)

sichuan university

45H指数

127论文数

9.4K被引数

收录论文 55

发表时间

Mechanistic basis of LolDF-mediated lipoprotein transport in Acinetobacter

Nature Communications

IF15.7

2026-08-15

OAAI

Jie Pang; Yawen Chen; Wen Qiao; Zijing Ju; Xiayu Zhu; Shenghai Chang; Lijue Wang; Zhibo Zhang; Zhaxi Zerang; Shuxian Xu; Yujiao Chen; Changshu Li; Binwu Ying; Bi-Sen Ding; Hao Chen; Shouyue Zhang; Xiawei Wei; Xiaodi Tang; Haohao Dong

Conformational hijacking of lipoprotein transporter LolDF enables precision antimicrobial activity against Acinetobacter baumannii 脂蛋白转运蛋白LolDF的构象劫持使其能够对鲍曼不动杆菌进行精准抗菌活性

Nature Communications

IF15.7

2026-07-11

OAAI

Jie Pang; Yawen Chen; Dengcheng Zhou; Lijue Wang; Yuling Xiao; Zhibo Zhang; Zhaxi Zerang; Maolin Duan; Lele Zhang; Xiang Gu; Min Xiao; Jingyu Wang; Hui Cui; Aijia Wen; Shouyue Zhang; Yiwen Zhang; Binwu Ying; Liang Ouyang; Xiawei Wei; Bi-Sen Ding; Xiaodi Tang; Haohao Dong

Single-cell multiomics uncovers an endothelial mechanosensitive PIEZO1-IL-33 axis driving pulmonary fibrosis 单细胞多组学揭示了驱动肺纤维化的内皮机械敏感性PIEZO1-IL-33轴。

Nature Communications

IF15.7

2026-03-20

OAAI

Lanlan Zhang; Xuezhen Gui; Ruijie Hou; Liping Jia; Shu Xia; Xin Zhang; Yingyun Fu; Qian-Fang Meng; Qun Luo; Xing Shi; Bingxin Guo; Ruifang Liang; Ludan Yue; Xue Chen; Haizhao Xu; Pengbo Wang; Xia Tong; Lujie Liu; Lingwei Wang; Baicun Li; Zi Chen; Linfu Zhou; Linshu Zhang; Rongchang Chen; Changbin Sun; Wei Xu; Lang Rao; Haibo Zhou; Bi-Sen Ding; Shanze Chen

Deciphering the molecular mechanism of the bacterial division motor TolQRA 解析细菌分裂马达TolQRA的分子机制

Cell Discovery

IF12.5

2025-11-04

OAAI

Chongrong Shen; Teng Xie; Yongbo Luo; Fangyuan Zhao; Xin Wang; Zhibo Zhang; Jie Pang; Jierou Zhang; Xintan Dong; Shenghai Chang; Bi-Sen Ding; Binwu Ying; Wei Chi; Zhaoming Su; Ruhong Zhou; Xiaodi Tang; Haohao Dong

Inhibition of KDM6B prevents osteoarthritis by blocking growth plate-like H3K27me3 loss in bivalent genes KDM6B的抑制通过阻断双价基因中类生长板样H3K27me3的丢失来预防骨关节炎

SCIENCE CHINA-LIFE SCIENCES

IF9.5

2025-02-17

PREAI

Du, Hao; Zhang, Yao; Yu, Xi; You, Xuanhe; Wu, Diwei; Du, Ze; Cai, Yongrui; Luo, Zhenyu; Lu, Hanpeng; Liao, Zhixin; Ding, Bi-Sen; Zhao, Ya; Wang, Yan; Xiao, Ke; Yang, Fan; Gan, Fangji; Ning, Ning; Zeng, Jiancheng; Shi, Peiliang; Zhou, Zongke

Angiocrine signaling in sinusoidal homeostasis and liver diseases 窦内稳态和肝脏疾病中的血管分泌信号

JOURNAL OF HEPATOLOGY

IF33

2024-09-01

PREAI

Gao, Jinhang; Lan, Tian; Kostallari, Enis; Guo, Yangkun; Lai, Enjiang; Guillot, Adrien; Ding, Bisen; Tacke, Frank; Tang, Chengwei; Shah, Vijay H.

Inhibiting endothelial Rhoj blocks profibrotic vascular intussusception and angiocrine factors to sustain lung regeneration

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2024-08-28

PREAI

Ma, Jie; Zhang, Liyin; Zhang, Xu; Zhang, Lanlan; Zhang, Hua; Zhu, Yulei; Huang, Xingming; Zhang, Ting; Tang, Xiangdong; Wang, Yuan; Chen, Lu; Pu, Qiang; Yang, Liming; Cao, Zhongwei; Ding, Bi-Sen

Structural insights into the activation of the divisome complex FtsWIQLB

CELL DISCOVERY

IF12.5

2024-01-03

OAAI

Yang, Lili; Chen, Yujiao; Chang, Shenghai; Shen, Chongrong; Wang, Xin; Zhang, Changbin; Zhang, Zhibo; Ding, Bi-Sen; Su, Zhaoming; Dong, Haohao; Tang, Xiaodi

The Aging Biomarker Consortium represents a new era for aging research in China

NATURE MEDICINE

IF50

2023-07-19

PREAI

Ren, Jie; Song, Moshi; Zhang, Weiqi; Cai, Jian-Ping; Cao, Feng; Cao, Zhongwei; Chan, Piu; Chen, Chang; Chen, Guobing; Chen, Hou-Zao; Chen, Jun; Chen, Xiao-Chun; Ci, Weimin; Ding, Bi-Sen; Ding, Qiurong; Gao, Feng; Gao, Shaorong; Han, Jing-Dong J.; He, Qi-Yang; Huang, Kai; Ju, Zhenyu; Kong, Qing-Peng; Li, Ji; Li, Jian; Li, Jingyi; Li, Xin; Liu, Baohua; Liu, Feng; Liu, Jun-Ping; Liu, Lin; Liu, Qiang; Liu, Qiang; Liu, Xingguo; Liu, Yong; Luo, Xianghang; Ma, Shuai; Ma, Xinran; Mao, Zhiyong; Nie, Jing; Peng, Yaojin; Qu, Jing; Ren, Ruibao; Song, Weihong; Songyang, Zhou; Sun, Liang; Sun, Yi Eve; Sun, Yu; Tian, Mei; Tian, Xiao-Li; Tian, Ye; Wang, Jianwei; Wang, Shusen; Wang, Si; Wang, Wengong; Wang, Xia; Wang, Xiaoning; Wang, Yan-Jiang; Wang, Yunfang; Wong, Catherine C. L.; Xiang, Andy Peng; Xiao, Yichuan; Xiao, Zhi-Xiong; Xie, Zhengwei; Xiong, Wei; Xu, Daichao; Yang, Ze; Ye, Jing; Yu, Wei; Yue, Rui; Zhang, Cuntai; Zhang, Hongbo; Zhang, Liang; Zhang, Xinchao; Zhang, Yong; Zhang, Yun-Wu; Zhang, Zhuohua; Zhao, Tongbiao; Zhao, Yuzheng; Zhou, Zhongjun; Zhu, Dahai; Zou, Weiguo; Pei, Gang; Liu, Guang-Hui

Integrated analyses of single-cell transcriptomics identify metastasis-associated myeloid subpopulations in breast cancer lung metastasis

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-07-07

OAAI

Huang, Zhen; Bu, Dawei; Yang, Nan; Huang, Wenwen; Zhang, Liyin; Li, Xiaoxue; Ding, Bi-Sen

Deficiency of endothelial FGFR1 signaling via upregulation of ROCK2 activity aggravated ALI/ARDS 通过上调ROCK2活性而导致的内皮FGFR1信号通路缺陷加重了ALI/ARDS

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-03-10

OAAI

Deng, Yue; Huang, Xingming; Hu, Yan; Zhong, Weiting; Zhang, Hua; Mo, Chunheng; Wang, Hongjun; Ding, Bi-Sen; Wang, Chen

Aging breaks liver vascular 'zone defense'

NATURE AGING

IF19.4

2023-02-20

PREAI

Cao, Zhongwei; Ding, Bi-Sen

Regenerative failure of intrahepatic biliary cells in Alagille syndrome rescued by elevated Jagged/Notch/Sox9 signaling

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-12-05

OAAI

Zhao, Chengjian; Matalonga, Jonathan; Lancman, Joseph J.; Liu, Lu; Xiao, Chaoxin; Kumar, Shiv; Gates, Keith P.; He, Jiaye; Graves, Alyssa; Huisken, Jan; Azuma, Mizuki; Lu, Zhenghao; Chen, Chong; Ding, Bi-Sen; Dong, P. Duc Si

Comprehensive Review of the Vascular Niche in Regulating Organ Regeneration and Fibrosis

STEM CELLS TRANSLATIONAL MEDICINE

IF4.9

2022-09-28

OAAI

Chen, Yutian; Ding, Bi-Sen

Trimethylamine-N-oxide (TMAO) mediates the crosstalk between the gut microbiota and hepatic vascular niche to alleviate liver fibrosis in nonalcoholic steatohepatitis

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-08-22

OAAI

Zhou, Dengcheng; Zhang, Jing; Xiao, Chengju; Mo, Chunheng; Ding, Bi-Sen

Targeting fibrosis: mechanisms and clinical trials 靶向纤维化: 机制和临床试验

Signal Transduction and Targeted Therapy

IF52.7

2022-06-30

OAAI

Manyu Zhao; Liqun Wang; Mengzhu Wang; Shijie Zhou; Ying Lu; Huijie Cui; Alexandra C. Racanelli; Ling Zhang; Tinghong Ye; Bisen Ding; Ben Zhang; Jinliang Yang; Yuqin Yao

Integrative network analysis of early-stage lung adenocarcinoma identifies aurora kinase inhibition as interceptor of invasion and progression

NATURE COMMUNICATIONS

IF15.7

2022-03-24

OAAI

Yoo, Seungyeul; Sinha, Abhilasha; Yang, Dawei; Altorki, Nasser K.; Tandon, Radhika; Wang, Wenhui; Chavez, Deebly; Lee, Eunjee; Patel, Ayushi S.; Sato, Takashi; Kong, Ranran; Ding, Bisen; Schadt, Eric E.; Watanabe, Hideo; Massion, Pierre P.; Borczuk, Alain C.; Zhu, Jun; Powell, Charles A.

Dopamine receptor D2 antagonism normalizes profibrotic macrophage-endothelial crosstalk in non-alcoholic steatohepatitis

JOURNAL OF HEPATOLOGY

IF33

2022-02-01

PREAI

Qing, Jie; Ren, Yafeng; Zhang, Yuwei; Yan, Mengli; Zhang, Hua; Wu, Dongbo; Ma, Yongyuan; Chen, Yutian; Huang, Xiaojuan; Wu, Qinkai; Mazhar, Maryam; Wang, Li; Liu, Jian; Ding, Bi-Sen; Cao, Zhongwei

Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability

NATURE CELL BIOLOGY

IF19.1

2021-12-27

OAAI

Guo, Peipei; Liu, Ying; Geng, Fuqiang; Daman, Andrew W.; Liu, Xiaoyu; Zhong, Liangwen; Ravishankar, Arjun; Lis, Raphael; Duran, Jose Gabriel Barcia; Itkin, Tomer; Tang, Fanying; Zhang, Tuo; Xiang, Jenny; Shido, Koji; Ding, Bi-sen; Wen, Duancheng; Josefowicz, Steven Z.; Rafii, Shahin

Reversal of emphysema by restoration of pulmonary endothelial cells

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2021-07-21

OAAI

Hisata, Shu; Racanelli, Alexandra C.; Kermani, Pouneh; Schreiner, Ryan; Houghton, Sean; Palikuqi, Brisa; Kunar, Balvir; Zhou, Aiyuan; McConn, Keith; Capili, Allyson; Redmond, David; Nolan, Daniel J.; Ginsberg, Michael; Ding, Bi-Sen; Martinez, Fernando J.; Scandura, Joseph M.; Cloonan, Suzanne M.; Rafii, Shahin; Choi, Augustine M. K.

研究方向

肺和肝等器官的再生和纤维化（结疤）反应血管旁分泌(Angiocrine)功能对器官修复的调控靶向血管Angiocrine功能器官再生纤维化防止生物化学，细胞生物学，生物技术等【代表性论著】肺毛细血管靶向肺泡修复纤维化改善9(415):ec31药物发现doi: 10.1038/nrd.2016.25血管内皮细胞血管分泌功能内皮TPI1多巴胺化铁死亡血管分泌信号肺再生内皮Rhoj抑制促纤维化血管套叠表观遗传血管生态位肝纤维化非酒精性脂肪性肝炎AgingHematopoietic-Vascular NicheRegenerationFibrosis衰老鞘氨醇-1-磷酸ApoM器官修复22再生疗法肺纤维化血小板衍生SDF-1驱动肺泡再生血管微环境信号肝脏再生与纤维化平衡7(307):ec76(224):ec33.肿瘤干细胞化疗耐药性分子检查点31(1):110-126.Angiocrine signals from tumor vascular nicheB-cell lymphoma invasiveness and chemoresistance25, 261–263Nature Reviews Cancer 2014doi:10.1038/nrc3730Science Signaling 20147: p. ec85内皮源性血管分泌信号肺肺泡再生Highlighted in Cell 2011147(3):485-7血管生成信号肝再生

合作学者

合作期刊

Scott W. Lowe

H 指数: 156 · 论文数: 978

Fernando J. Martínez

H 指数: 156 · 论文数: 1.3K

Ronald G. Crystal

H 指数: 154 · 论文数: 1.1K