logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
D

David Spetzler

caris life sciences
H指数:26
被引数:9,503

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Corrigendum to “Whole-exome sequencing provides assessment of homologous recombination deficiency for identification of PARPi-responsive ovarian tumors” [Gynecol. Oncol. 197 (2025) 139–145]

勘误：“全外显子组测序为评估同源重组缺陷以识别对PARPi敏感的卵巢肿瘤” [Gynecol. Oncol. 197 (2025) 139–145]

Gynecologic Oncology
IF4.1
2026-10-210
PRE
Elizabeth Evans; Jhalak Dholakia; Jim Abraham; Andrew Hinton; Jian Zhang; Joanne Xiu; Todd Maney; Matt Oberley; Premal Thaker; Thomas Herzog; David Spetzler; Rebecca C. Arend
The conformation-selective PI3Kδ inhibitor roginolisib in patients with advanced or metastatic cancer, including metastatic uveal melanoma: first-in-human clinical trial

在晚期或转移性癌症患者中具有构象选择性的PI3Kδ抑制剂roginolisib的临床试验：首次人体试验，包括转移性葡萄膜黑色素瘤

Nature Communications
IF15.7
2026-10-090
OAAI
Anna Maria Di Giacomo; Matteo Simonelli; Agnese Losurdo; Pavlina Spiliopoulou; Vincenzo D’Alonzo; Giovanni Amato; Monica Valente; Hugo Barcenilla; Anette Johnsson; Laura Gonzalez; Ziyang Tan; Lakshmikanth Tadepally; Petter Brodin; Michael Lahn; Giusy Di Conza; Rebeca Zorrilla; Lars van der Veen; Alessio Bevilacqua; Paramjit Kaur; Tracey Hammett; Marco Durini; Andrea Corsi; Nikhil Sindhwani; Mariaelena Occhipinti; Robert Snijder; Ayad Abdul-Ahad; Aniko Meijer; Umberto Postiglione; Gregory Price; Gillian Hopton; Emily Wood; Vincent Vuaroqueaux; Anne-Lise Peille; Jill Graham; Ming Poi; David Spetzler; Carmelo Carlo-Stella; Armando Santoro; Thomas R. Jeffry Evans; Michele Maio
Broader gene representation by whole-exome sequencing improves accuracy of tumor mutational burden assessment for selection of pembrolizumab immunotherapy

全外显子组测序获得更广泛的基因表达可提高肿瘤突变负荷评估的准确性，以选择帕博利珠单抗免疫疗法

cancer immunology, immunotherapy
IF0
2026-05-110
OAAI
Milan Radovich; James Wacker; Jeffrey Solzak; Hongseok Tae; Jennifer R. Ribeiro; Todd Maney; Bradley Hancock; James Hamrick; George W. Sledge; Manmeet S. Ahluwalia; Stephen V. Liu; Emil Lou; Vivek Subbiah; Balazs Halmos; Daniel Magee; David B. Spetzler
Genomic and Immune Correlates of EZH2 Expression and Activity in Olfactory Neuroblastoma

EZH2表达和活性的基因组与免疫相关性在嗅神经母细胞瘤中的研究

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
IF2.2
2025-11-010
OAAI
Xue, Elisabetta; Adeyelu, Tolulope; Krause, Harris; Elliott, Andrew; Mehra, Ranee; Soares, Heloisa; Lou, Emil; Vanderwalde, Ari; Spetzler, David; Bracken-clarke, Dara; London, Nyall R.; Gulley, James L.; Floudas, Charalampos S.
Author Correction: Synergistic H&E and IHC image analysis by AI predicts cancer biomarkers and survival outcomes in colorectal and breast cancer

作者更正：AI协同H&E和IHC图像分析预测结直肠癌和乳腺癌的癌症生物标志物和生存结局

Communications Medicine
IF6.3
2025-10-240
OA
Yating Cheng; Norsang Lama; Ming Chen; Eghbal Amidi; Mohammadreza Ramzanpour; Md Ashequr Rahman; Joanne Xiu; Anthony Helmstetter; Lauren Dickman; Jennifer R. Ribeiro; Hassan Ghani; Matthew Oberley; David Spetzler; George W. Sledge
Synergistic H&E and IHC image analysis by AI predicts cancer biomarkers and survival outcomes in colorectal and breast cancer

人工智能协同分析H&E与IHC图像，预测结直肠癌和乳腺癌的癌生物标志物及生存结局

Communications Medicine
IF6.3
2025-08-010
OAAI
Yating Cheng; Norsang Lama; Ming Chen; Egbhal Amidi; Mohammadreza Ramzanpour; Md Ashequr Rahman; Joanne Xiu; Anthony Helmstetter; Lauren Dickman; Jennifer R. Ribeiro; Hassan Ghani; Matthew Oberley; David Spetzler; George W. Sledge
REFINE: a database of linked clinical data and genomic biomarkers in renal cell carcinoma patients receiving immunotherapy-based treatment regimens

REFINE：接受基于免疫疗法治疗方案的肾细胞癌患者中，包含关联临床数据和基因组生物标志物的数据库

ONCOLOGIST
IF4.2
2025-06-010
OAAI
Zhong, Jeffrey; Jang, Albert; Abuqayas, Bashar; Basu, Arnab; Benjamin, David J.; Bhatlapenumarthi, Vineel; Bilen, Mehmet Asim; Buch, Dhvani; Chang, Mark; Chin, Erica; Darabi, Sourat; Dhanikonda, Nagendra; Ghatalia, Pooja; Grigg, Claud M.; Grier, Abby L.; Jindal, Tanya; Jung, Joannah; Kilari, Deepak; Kumar, Hamsa L. S.; Lee, Suzanna; Neelands, Brittany; Pandya, Chinmayi; Pawalek, Jeff; Staggers, Jaimee; Yildirim, Ahmet; Zakharia, Yousef; Zarrabi, Kevin K.; Zimmerman, Michael; Sledge, George; Spetzler, David; Elliott, Andrew; McKay, Rana R.; Barata, Pedro C.
Mutation burden and anti-PD-1 outcomes are not universally associated with immune cell infiltration or lymphoid activation

突变负担和抗PD-1疗效与免疫细胞浸润或淋巴样细胞激活之间并非普遍相关。

CANCER CELL
IF44.5
2024-12-010
PRE
Hsiehchen, David; Elliott, Andrew; Xiu, Joanne; Seeber, Andreas; El-Deiry, Wafik; Antonarakis, Emmanuel S.; Graff, Stephanie L.; Hall, Michael J.; Borghaei, Hossein; Hoon, Dave S. B.; V. Liu, Stephen; Ma, Patrick C.; Mckay, Rana R.; Wise-Draper, Trisha; Marshall, John; Sledge, George W.; Spetzler, David; Zhu, Hao
Temporal stability and chemotherapy responsiveness of classical and basal transcriptional subtypes of pancreatic cancer
CANCER RESEARCH
IF16.6
2024-09-150
PRE
Singh, Harshabad; Xiu, Joanne; Kapner, Kevin; Yuan, Chen; Narayan, Raja R.; Oberley, Matthew; Farrell, Alex; Surana, Rishi; Huffmann, Brandon M.; Perez, Kimberly J.; Cleary, James M.; Jordan, Alexander C.; Costa, Andressa Dias; Williams, Hannah L.; Raghavan, Srivatsan; Weinberg, Benjamin; Pishvaian, Michael J.; Shroff, Rachna T.; Goel, Sanjay; Dougan, Stephanie K.; Nowak, Jonathan; Spetzler, David; Sledge, George; Wolpin, Brian M.; Aguirre, Andrew J.
Tissue-specific thresholds of mutation burden associated with anti-PD-1/L1 therapy benefit and prognosis in microsatellite-stable cancers
NATURE CANCER
IF28.5
2024-03-252
PRE
Muquith, Maishara; Espinoza, Magdalena; Elliott, Andrew; Xiu, Joanne; Seeber, Andreas; El-Deiry, Wafik; Antonarakis, Emmanuel S.; Graff, Stephanie L.; Hall, Michael J.; Borghaei, Hossein; Hoon, Dave S. B.; Liu, Stephen V.; Ma, Patrick C.; McKay, Rana R.; Wise-Draper, Trisha; Marshall, John; Sledge, George W.; Spetzler, David; Zhu, Hao; Hsiehchen, David
Tissue- specific thresholds and microenvironment correlates of tumor mutation burden associated with immunotherapy benefit and prognosis in microsatellite stable cancers
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Muquith, Maishara; Espinoza, Magdalena; Elliott, Andrew; Xiu, Joanne; Seeber, Andreas; El-Deiry, Wafik; Antonarakis, Emmanuel S.; Graff, Stephanie; Hall, Michael J.; Borghaei, Hossein; Hoon, Dave S.; Liu, Stephen V.; Ma, Patrick C.; McKay, Rana R.; Wise-Draper, Trisha; Marshall, John; Sledge, George W.; Spetzler, David; Zhu, Hao; Hsieh, David

研究方向

暂未获取到该数据
J
Joanne Xiu
H 指数:37论文数:866被引数:6,638
M
Mark Miglarese
H 指数:15论文数:113被引数:1,254
G
George W. Sledge
H 指数:92论文数:1,019被引数:4.5万
A
Amy B. Heimberger
H 指数:88论文数:680被引数:3.0万
J
John L. Marshall
H 指数:83论文数:833被引数:2.6万
M
Matthew J. Oberley
H 指数:30论文数:344被引数:8,443
Z
Zoran Gatalica
H 指数:66论文数:704被引数:1.5万
A
Andrew Elliott
H 指数:18论文数:521被引数:1,223
J
Jim Abraham
H 指数:13论文数:101被引数:597
W
W. Michael Korn
H 指数:45论文数:629被引数:9,247