未登录 Volumetric (3D) compared with traditional bidirectional (2D) assessment in patients with Grade 2, isocitrate dehydrogenase 1/2 mutant (mIDH1/2) glioma receiving vorasidenib or placebo in the Phase 3 INDIGO trial 与接受vorasidenib或安慰剂治疗的Grade 2，异柠檬酸脱氢酶1/2突变（mIDH1/2）胶质瘤患者中，体素（3D）评估相较于传统双向（2D）评估在INDIGO III期试验中的比较 Ellingson, Benjamin M.; Mellinghoff, Ingo; Van Den Bent, Martin J.; Blumenthal, Deborah T.; Touat, Mehdi; Peters, Katherine B.; Clarke, Jennifer L.; Mendez, Joe; Yust-Katz, Shlomit; Welsh, Liam; Mason, Warren P.; Ducray, Francois; Umemura, Yoshie; Nabors, Burt; Holdhoff, Matthias; Hottinger, Andreas F.; Arakawa, Yoshiki; Sepulveda, Juan M.; Wick, Wolfgang; Soffietti, Riccardo; Perry, James; Giglio, Pierre; De La Fuente, Macarena, I; Maher, Elizabeth; Zhao, Dan; Pandya, Shuchi S.; Steelman, Lori; Hassan, Islam; Wen, Patrick Y.; Cloughesy, Timothy F. 分享 收藏
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Volumetric tumor growth rate (TGR) modeling predicts clinical outcomes in patients with Grade 2, isocitrate dehydrogenase 1/2 mutant (mIDH1/2) glioma receiving vorasidenib or placebo in the Phase 3 INDIGO trial 体积肿瘤生长率（TGR）建模预测了在INDIGO三期试验中，接受vorasidenib或安慰剂治疗的Grade 2、异柠檬酸脱氢酶1/2突变（mIDH1/2）胶质瘤患者的临床结局。 Ellingson, Benjamin M.; Mellinghoff, Ingo; Van Den Bent, Martin J.; Blumenthal, Deborah T.; Touat, Mehdi; Peters, Katherine B.; Clarke, Jennifer L.; Mendez, Joe; Yust-Katz, Shlomit; Welsh, Liam; Mason, Warren P.; Ducray, Francois; Umemura, Yoshie; Nabors, Burt; Holdhoff, Matthias; Hottinger, Andreas F.; Arakawa, Yoshiki; Sepulveda, Juan M.; Wick, Wolfgang; Soffietti, Riccardo; Perry, James; Giglio, Pierre; De La Fuente, Macarena, I; Maher, Elizabeth; Zhao, Dan; Pandya, Shuchi S.; Steelman, Lori; Hassan, Islam; Wen, Patrick Y.; Cloughesy, Timothy F. 分享 收藏
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EARLY TUMOR VOLUME CHANGES PREDICT CLINICAL OUTCOMES IN MIDH1/2 GLIOMA: POST-HOC RESULTS FROM THE PHASE 3 INDIGO TRIAL 早期肿瘤体积变化预测Midh1/2胶质瘤的临床结局：INDIGO III期试验的事后分析结果 Ellingson, B. M.; Mellinghoff, I. K.; van den Bent, M. J.; Blumenthal, D. T.; Touat, M.; Peters, K. B.; Clarke, J. L.; Mendez, J.; Yust-Katz, S.; Welsh, L.; Mason, W. P.; Ducray, F.; Umemura, Y.; Nabors, B.; Holdhoff, M.; Hottinger, A. F.; Arakawa, Y.; Sepulveda, J. M.; Wick, W.; Soffietti, R.; Perry, J.; Giglio, P.; de la Fuente, M.; Maher, E.; Zhao, D.; Pandya, S. S.; Steelman, L.; Hassan, I; Wen, P. Y.; Cloughesy, T. F. 分享 收藏
EXPLORATORY ANALYSES FROM PHASE 3 INDIGO STUDY SUGGEST POTENTIAL MECHANISM OF SEIZURE CONTROL THROUGH TUMOR VOLUME REDUCTION UNDER TREATMENT WITH VORASIDENIB 来自INDIGO研究第3阶段的探索性分析表明，在VORASIDENIB治疗下，通过肿瘤体积减小可能存在控制癫痫发作的潜在机制。 Wick, W.; Mellinghoff, I. K.; van den Bent, M. J.; Blumenthal, D. T.; Touat, M.; Peters, K. B.; Clarke, J. L.; Mendez, J.; Welsh, L.; Mason, W. P.; Hottinger, A. F.; Sepulveda, J. M.; Soffietti, R.; Zhao, D.; Yi, D.; Weidl, D.; Steelman, L.; Hassan, I; Wen, P. Y.; Cloughesy, T. F. 分享 收藏
A GLOBAL, RANDOMIZED, DOUBLE-BLINDED, PHASE 3 STUDY OF VORASIDENIB VERSUS PLACEBO IN PATIENTS WITH ADULT-TYPE DIFFUSE GLIOMA WITH AN IDH1/2 MUTATION (INDIGO): UPDATED EFFICACY RESULTS Mellinghoff, Ingo K.; van den Bent, Martin J.; Touat, Mehdi; Blumenthal, Deborah T.; Peters, Katherine B.; Ellingson, Benjamin M.; Clarke, Jennifer L.; Mendez, Joe; Yust-Katz, Shlomit; Mason, Warren P.; Ducray, Francois; Umemura, Yoshie; Nabors, Burt; Hottinger, Andreas F.; Arakawa, Yoshiki; Sepulveda, Juan M.; Wick, Wolfgang; Soffietti, Riccardo; Perry, James R.; Giglio, Pierre; de la Fuente, Macarena; Maher, Elizabeth A.; Tron, Adriana E.; Zhao, Dan; Pandya, Shuchi S.; Steelman, Lori; Hassan, Islam; Wen, Patrick Y.; Cloughesy, Timothy F. 分享 收藏
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A real-world observation of patients with glioblastoma treated with a personalized peptide vaccine Latzer, Pauline; Zelba, Henning; Battke, Florian; Reinhardt, Annekathrin; Shao, Borong; Bartsch, Oliver; Rabsteyn, Armin; Harter, Johannes; Schulze, Martin; Okech, Thomas; Golf, Alexander; Kyzirakos-Feger, Christina; Kayser, Simone; Pieper, Natalia; Feldhahn, Magdalena; Wuensche, Julian; Seitz, Christian; Hadaschik, Dirk; Garbe, Claus; Hauser, Till-Karsten; la Fougere, Christian; Biskup, Dirk; Brooke, Dawn; Parker, David; Martens, Uwe M.; Illerhaus, Gerald; Blumenthal, Deborah T.; Merrell, Ryan; Lorenzo, Luisa Sanchez; Hidvegi, Mate; de Robles, Paula; Kebir, Sied; Li, William W.; Li, Vincent W.; Williams, Matthew; Miller, Alexandra M.; Kesari, Santosh; Castro, Michael; Desjardins, Annick; Ashley, David M.; Friedman, Henry S.; Wen, Patrick Y.; Neil, Elisabeth C.; Iwamoto, Fabio M.; Sipos, Bence; Geletneky, Karsten; Zender, Lars; Glas, Martin; Reardon, David A.; Biskup, Saskia 分享 收藏
Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti-PD-1 Monotherapy: A Report from the International RRD Consortium 联合免疫疗法可改善Anti-PD-1单一疗法失败的复制修复缺陷 (RRD) 高级别神经胶质瘤的结果: 来自国际RRD联盟的报告 Das, Anirban; Fernandez, Nicholas R.; Levine, Adrian; Bianchi, Vanessa; Stengs, Lucie K.; Chung, Jiil; Negm, Logine; Dimayacyac, Jose Rafael; Chang, Yuan; Nobre, Liana; Ercan, Ayse B.; Sanchez-Ramirez, Santiago; Sudhaman, Sumedha; Edwards, Melissa; Larouche, Valerie; Samuel, David; Van Damme, An; Gass, David; Ziegler, David S.; Bielack, Stefan S.; Koschmann, Carl; Zelcer, Shayna; Yalon-Oren, Michal; Campino, Gadi Abede; Sarosiek, Tomasz; Nichols, Kim E.; De Mola, Rebecca Loret; Bielamowicz, Kevin; Sabel, Magnus; Frojd, Charlotta A.; Wood, Matthew D.; Glover, Jason M.; Lee, Yi-Yen; Vanan, Magimairajan; Adamski, Jenny K.; Perreault, Sebastien; Chamdine, Omar; Hjort, Magnus Aasved; Zapotocky, Michal; Carceller, Fernando; Wright, Erin; Fedorakova, Ivana; Lossos, Alexander; Tanaka, Ryuma; Osborn, Michael; Blumenthal, Deborah T.; Aronson, Melyssa; Bartels, Ute; Huang, Annie; Ramaswamy, Vijay; Malkin, David; Shlien, Adam; Villani, Anita; Dirks, Peter B.; Pugh, Trevor J.; Getz, Gad; Maruvka, Yosef E.; Tsang, Derek S.; Ertl-Wagner, Birgit; Hawkins, Cynthia; Bouffet, Eric; Morgenstern, Daniel A.; Tabori, Uri 分享 收藏
INDIGO: A randomized, double-blinded, phase III study of vorasidenib versus placebo in IDH1 or IDH2 low-grade glioma Blumenthal, D.; Mellinghoff, I. K.; van den Bent, M. J.; Touat, M.; Peters, K.; Clarke, J.; Mendez, J.; Welsh, L.; Mason, W.; Hottinger, A. F.; Sepulveda Sanchez, J. M.; Wick, W.; Soffietti, R.; Tron, A.; Zhao, D.; Pandya, S.; Steelman, L.; Hassan, I.; Wen, P.; Cloughesy, T. 分享 收藏
INDIGO: A GLOBAL, RANDOMIZED, DOUBLE-BLINDED, PHASE III STUDY OF VORASIDENIB VERSUS PLACEBO IN PATIENTS WITH RESIDUAL OR RECURRENT GRADE 2 GLIOMA WITH AN IDH1/2 MUTATION Mellinghoff, I. K.; van den Bent, M. J.; Blumenthal, D. T.; Touat, M.; Peters, K. B.; Clarke, J.; Mendez, J.; Welsh, L.; Mason, W. P.; Hottinger, A. F.; Sepulveda, J. M.; Wick, W.; Soffietti, R.; Schoenfeld, S.; Zhao, D.; Pandya, S.; Steelman, L.; Hassan, I.; Wen, P. Y.; Cloughesy, T. F. 分享 收藏
Vorasidenib in IDH1-or IDH2-Mutant Low-Grade Glioma Mellinghoff, Ingo K.; van den Bent, Martin J.; Blumenthal, Deborah T.; Touat, Mehdi; Peters, Katherine B.; Clarke, Jennifer; Mendez, Joe; Yust-Katz, Shlomit; Welsh, Liam; Mason, Warren P.; Ducray, Francois; Umemura, Yoshie; Nabors, Burt; Holdhoff, Matthias; Hottinger, Andreas F.; Arakawa, Yoshiki; Sepulveda, Juan M.; Wick, Wolfgang; Soffietti, Riccardo; Perry, James R.; Giglio, Pierre; de la Fuente, Macarena; Maher, Elizabeth A.; Schoenfeld, Steven; Zhao, Dan; Pandya, Shuchi S.; Steelman, Lori; Hassan, Islam; Wen, Patrick Y.; Cloughesy, Timothy F. 分享 收藏
Collaborative privacy-preserving analysis of oncological data using multiparty homomorphic encryption Geva, Ravit; Gusev, Alexander; Polyakov, Yuriy; Liram, Lior; Rosolio, Oded; Alexandru, Andreea; Genise, Nicholas; Blatt, Marcelo; Duchin, Zohar; Waissengrin, Barliz; Mirelman, Dan; Bukstein, Felix; Blumenthal, Deborah T.; Wolf, Ido; Pelles-Avraham, Sharon; Schaffer, Tali; Lavi, Lee A.; Micciancio, Daniele; Vaikuntanathan, Vinod; Al Badawi, Ahmad; Goldwasser, Shafi 分享 收藏
Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival following Immunotherapy in Murine GBM. Ziv, Michal Nisnboym; Vincze, Sarah R.; Raphael, Itay; Xiong, Zujian; Sneiderman, Chaim T.; Raphael, Rebecca A.; Li, Bo; Jaswal, Ambika P.; Sever, ReidAnn; Day, Kathryn E.; LaToche, Joseph D.; Foley, Lesley M.; Hitchens, T. Kevin; Agnihotri, Sameer; Hu, Baoli; Rajasundaram, Dhivyaa; Anderson, Carolyn J.; Blumenthal, Deborah T.; Pearce, Thomas M.; Uttam, Shikhar; Nedrow, Jessie R.; Panigrahy, Ashok; Pollack, Ian F.; Lieberman, Frank S.; Drappatz, Jan; Edwards, Wilson B.; Kohanbash, Gary 分享 收藏
A Prospective, Cohort Study of SITOIGANAP to Treat Glioblastoma When Given in Combination With Granulocyte-Macrophage Colony-Stimulating Factor/Cyclophosphamide/Bevacizumab/Nivolumab or Granulocyte-Macrophage Colony-Stimulating Factor/Cyclophosphamide/Bevacizumab/Pembrolizumab in Patients Who Failed Prior Treatment With Surgical Resection, Radiation, and Temozolomide Bota, Daniela A.; Taylor, Thomas H.; Lomeli, Naomi; Kong, Xiao-Tang; Fu, Beverly D.; Schonthal, Axel H.; Singer, Samuel; Blumenthal, Deborah T.; Senecal, Frank M.; Linardou, Helena; Rokas, Evangelos; Antoniou, Dimitris G.; Schijns, Virgil E. J. C.; Chen, Thomas C.; Elliot, Joseph; Stathopoulos, Apostolos 分享 收藏
Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency 生殖系DNA复制修复缺陷儿童对PD-1抑制反应的基因组预测因子 Das, Anirban; Sudhaman, Sumedha; Morgenstern, Daniel; Coblentz, Ailish; Chung, Jiil; Stone, Simone C.; Alsafwani, Noor; Liu, Zhihui Amy; Abu Al Karsaneh, Ola; Soleimani, Shirin; Ladany, Hagay; Chen, David; Zatzman, Matthew; Cabric, Vanja; Nobre, Liana; Bianchi, Vanessa; Edwards, Melissa; Nahum, Lauren C. Sambira; Ercan, Ayse B.; Nabbi, Arash; Constantini, Shlomi; Dvir, Rina; Yalon-Oren, Michal; Campino, Gadi Abebe; Caspi, Shani; Larouche, Valerie; Reddy, Alyssa; Osborn, Michael; Mason, Gary; Lindhorst, Scott; Bronsema, Annika; Magimairajan, Vanan; Opocher, Enrico; De Mola, Rebecca Loret; Sabel, Magnus; Frojd, Charlotta; Sumerauer, David; Samuel, David; Cole, Kristina; Chiaravalli, Stefano; Massimino, Maura; Tomboc, Patrick; Ziegler, David S.; George, Ben; Van Damme, An; Hijiya, Nobuko; Gass, David; McGee, Rose B.; Mordechai, Oz; Bowers, Daniel C.; Laetsch, Theodore W.; Lossos, Alexander; Blumenthal, Deborah T.; Sarosiek, Tomasz; Yen, Lee Yi; Knipstein, Jeffrey; Bendel, Anne; Hoffman, Lindsey M.; Luna-Fineman, Sandra; Zimmermann, Stefanie; Scheers, Isabelle; Nichols, Kim E.; Zapotocky, Michal; Hansford, Jordan R.; Maris, John M.; Dirks, Peter; Taylor, Michael D.; Kulkarni, Abhaya, V; Shroff, Manohar; Tsang, Derek S.; Villani, Anita; Xu, Wei; Aronson, Melyssa; Durno, Carol; Shlien, Adam; Malkin, David; Getz, Gad; Maruvka, Yosef E.; Ohashi, Pamela S.; Hawkins, Cynthia; Pugh, Trevor J.; Bouffet, Eric; Tabori, Uri 分享 收藏
Independently validated sex-specific nomograms for predicting survival in patients with newly diagnosed glioblastoma: NRG Oncology RTOG 0525 and 0825 Patil, Nirav; Somasundaram, Eashwar; Waite, Kristin A.; Lathia, Justin D.; Machtay, Mitchell; Gilbert, Mark R.; Connor, James R.; Rubin, Joshua B.; Berens, Michael E.; Buerki, Robin A.; Choi, Serah; Sloan, Andrew E.; Penas-Prado, Marta; Ashby, Lynn S.; Blumenthal, Deborah T.; Werner-Wasik, Maria; Hunter, Grant K.; Flickinger, John C.; Wendland, Merideth M.; Panet-Raymond, Valerie; Robins, H. Ian; Pugh, Stephanie L.; Mehta, Minesh P.; Barnholtz-Sloan, Jill S. 分享 收藏
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Global post-marketing safety surveillance of Tumor Treating Fields (TTFields) in patients with high-grade glioma in clinical practice (vol 148, pg 489, 2020) Shi, Wenyin; Blumenthal, Deborah T.; Bush, Nancy Ann Oberheim; Kebir, Sied; Lukas, Rimas V.; Muragaki, Yoshihiro; Zhu, Jay-Jiguang; Glas, Martin 分享 收藏
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