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Biomarker-directed targeted therapy plus durvalumab in advanced non-small-cell lung cancer: a phase 2 umbrella trial 生物标志物定向靶向治疗联合durvalumab治疗晚期非小细胞肺癌: 2期伞形试验 Besse, Benjamin; Pons-Tostivint, Elvire; Park, Keunchil; Hartl, Sylvia; Forde, Patrick M.; Hochmair, Maximilian J.; Awad, Mark M.; Thomas, Michael; Goss, Glenwood; Wheatley-Price, Paul; Shepherd, Frances A.; Florescu, Marie; Cheema, Parneet; Chu, Quincy S. C.; Kim, Sang-We; Morgensztern, Daniel; Johnson, Melissa L.; Cousin, Sophie; Kim, Dong-Wan; Moskovitz, Mor T.; Vicente, David; Aronson, Boaz; Hobson, Rosalind; Ambrose, Helen J.; Khosla, Sajan; Reddy, Avinash; Russell, Deanna L.; Keddar, Mohamed Reda; Conway, James P.; Barrett, J. Carl; Dean, Emma; Kumar, Rakesh; Dressman, Marlene; Jewsbury, Philip J.; Iyer, Sonia; Barry, Simon T.; Cosaert, Jan; Heymach, John V. 分享 收藏
Xevinapant plus avelumab in patients (pts) with advanced or metastatic non-small cell lung cancer (NSCLC): Phase 1b dose-expansion results and exploratory biomarker analyses Chu, Quincy; Ciuleanu, Tudor; Ramlau, Rodryg; Renouf, Daniel; Juergens, Rosalyn; Kalinka, Ewa; Sawrycki, Piotr; Bramson, Jonathan; Nelson, Brad; Crabbe, Rafael; Sahlender, Daniela A.; Crompton, Philippa; Rouits, Elisabeth; Spaggiari, Dany; Brichory, Franck; Piggott, Luke; Schenker, Mike; Goss, Glenwood 分享 收藏
Novel Nanoparticle-Based Cancer Treatment, Effectively Inhibits Lung Metastases and Improves Survival in a Murine Breast Cancer Model Kraus, Sarah; Khandadash, Raz; Hof, Raphael; Nyska, Abraham; Sigalov, Ekaterina; Eltanani, Moshe; Rukenstein, Pazit; Rabinovitz, Ricarina; Kassem, Rana; Antebi, Adam; Shalev, Ofer; Cohen-Erner, Moshe; Goss, Glenwood; Cyjon, Arnoldo 分享 收藏
Afatinib versus erlotinib as second-line treatment of patients with advanced squamous cell carcinoma of the lung: Final analysis of the randomised phase 3 LUX-Lung 8 trial Goss, Glenwood D.; Cobo, Manuel; Lu, Shun; Syrigos, Konstantinos; Lee, Ki Hyeong; Goker, Erdem; Georgoulias, Vassilis; Isla, Dolores; Morabito, Alessandro; Min, Young J.; Ardizzoni, Andrea; Bender, Shaun; Cseh, Agnieszka; Felip, Enriqueta 分享 收藏
CodeBreak 200: A phase III multicenter study of sotorasib (AMG 510), a KRAS(G12C) inhibitor, versus docetaxel in patients with previously treated advanced non-small cell lung cancer (NSCLC) harboring KRAS p.G12C mutation CodeBreak 200: 一项针对KRAS(G12C) 抑制剂sotorasib (AMG 510) 与多西他赛在先前治疗过的携带KRAS p.G12C突变的晚期非小细胞肺癌 (NSCLC) 患者中的III期多中心研究 Reck, M.; Spira, A.; Besse, B.; Wolf, J.; Skoulidis, F.; Borghaei, H.; Goto, K.; Park, K.; Griesinger, F.; Felip, E.; Boyer, M.; Barrios, C. H.; Goss, G.; Yang, H.; Obiozor, C.; Ramalingam, S. S. 分享 收藏
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Osimertinib in Patients With T790M Mutation-Positive, Advanced Non-Small Cell Lung Cancer: Long-Term Follow-Up From a Pooled Analysis of 2 Phase 2 Studies Ahn, Myung-Ju; Tsai, Chun-Ming; Shepherd, Frances A.; Bazhenova, Lyudmila; Sequist, Lecia, V; Hida, Toyoaki; Yang, James C. H.; Ramalingam, Suresh S.; Mitsudomi, Tetsuya; Janne, Pasi A.; Mann, Helen; Cantarini, Mireille; Goss, Glenwood 分享 收藏
Canadian Cancer Trials Group (CCTG) IND215: A phase Ib study of Selumetinib in patients with untreated advanced or metastatic NSCLC who are receiving standard chemotherapy regimens Goffin, J. R.; Nicholas, G.; Mates, M.; Tu, D.; Chen, E.; Laurie, S. A.; Juergens, R.; Robinson, A.; Goss, G.; Reaume, M.; Sun, S.; Christink, K.; Maize, C.; MacFarlan, S.; Sun, X.; Ritter, H.; Seymour, L.; Bradbury, P. A. 分享 收藏
Update on International Cooperative Groups Studies in Thoracic Malignancies: The Emergence of Immunotherapy Shukla, Navika D.; Salahudeen, Ameen A.; Taylor, Gregory A.; Ramalingam, Suresh S.; Vokes, Everett E.; Goss, Glenwood D.; Decker, Roy H.; Kelly, Karen; Scagliotti, Giorgio V.; Mok, Tony S.; Wakelee, Heather A. 分享 收藏
Efficacy and Safety Results of Depatuxizumab Mafodotin (ABT-414) in Patients With Advanced Solid Tumors Likely to Overexpress Epidermal Growth Factor Receptor Goss, Glenwood D.; Vokes, Everett E.; Gordon, Michael S.; Gandhi, Leena; Papadopoulos, Kyriakos P.; Rasco, Drew W.; Fischer, JuDee S.; Chu, Katharine L.; Ames, William W.; Mittapalli, Rajendar K.; Lee, Ho-Jin; Zeng, Jiewei; Roberts-Rapp, Lisa A.; Loberg, Lise I.; Ansell, Peter J.; Reilly, Edward B.; Ocampo, Christopher J.; Holen, Kyle D.; Tolcher, Anthony W. 分享 收藏
CNS response to osimertinib in patients with T790M-positive advanced NSCLC: pooled data from two phase II trials T790M-positive晚期NSCLC患者对奥希替尼的中枢神经系统反应: 来自两项II期试验的汇总数据 Goss, G.; Tsai, C-M; Shepherd, F. A.; Ahn, M-J; Bazhenova, L.; Crino, L.; de Marinis, F.; Felip, E.; Morabito, A.; Hodge, R.; Cantarini, M.; Johnson, M.; Mitsudomi, T.; Janne, P. A.; Yang, J. C-H 分享 收藏
Symptom and Quality of Life Improvement in LUX-Lung 8, an Open-Label Phase III Study of Second-Line Afatinib Versus Erlotinib in Patients With Advanced Squamous Cell Carcinoma of the Lung After First-Line Platinum-Based Chemotherapy Felip, Enriqueta; Hirsh, Vera; Popat, Sanjay; Cobo, Manuel; Fulop, Andrea; Dayen, Charles; Trigo, Jose M.; Gregg, Richard; Waller, Cornelius F.; Soria, Jean-Charles; Goss, Glenwood D.; Gordon, James; Wang, Bushi; Palmer, Michael; Ehrnrooth, Eva; Gadgeel, Shirish M. 分享 收藏
Overview of Thoracic Oncology Trials in Cooperative Groups Around the Globe Salahudeen, Ameen Abdulla; Patel, Manali I.; Baas, Paul; Curran, Walter J.; Bradley, Jeffrey D.; Gandara, David R.; Goss, Glenwood D.; Mok, Tony S.; Ramalingam, Suresh S.; Vokes, Everett E.; Malik, Shakun M.; Wakelee, Heather A. 分享 收藏
A fatinib (A) vs erlotinib (E) as second-line treatment of patients (pts) with advanced squamous cell carcinoma (SCC) of the lung: LUX-Lung 8 (LL8), a phase III trial Gadgeel, Shirish; Soria, Jean-Charles; Felip, Enriqueta; Cobo, Manuel; Lu, Shun; Syrigos, Konstantinos; Lee, Ki Hyeong; Goker, Erdem; Georgoulias, Vassileios; Li, Wei; Isla, Dolores; Guclu, Salih Zeki; Morabito, Alessandro; Min, Young Joo; Ardizzoni, Andreas; Wang, Bushi; Chand, Vikram; Goss, Glenwood 分享 收藏
LUX-Lung 8: A Global Phase III Trial of Afatinib (A) vs Erlotinib (E) as Second-Line Treatment in Patients (Pts) With Advanced Squamous Cell Carcinoma (SCC) of the Lung Following First-Line Platinum-Based Chemotherapy Hirsh, Vera; Gadgeel, Shirish; Soria, Jean-Charles; Felip, Enriqueta; Cobo, Manuel; Lu, Shun; Syrigos, Konstantinos; Lee, Ki Hyeong; Goeker, Erdem; Georgoulias, Vassilis; Li, Wei; Isla, Dolores; Guclu, Salih Zeki; Morabito, Alessandro; Min, Young Joo; Ardizzoni, Andrea; Cromer, Jamie; Wang, Bushi; Chand, Vikram; Goss, Glenwood 分享 收藏
AZD9291 activity in patients with EGFR-mutant advanced non-small cell lung cancer (NSCLC) and brain metastases: Data from Phase II studies Ahn, M. J.; Tsai, C. M.; Yang, J. C. H.; Shepherd, F. A.; Satouchi, M.; Kim, D. W.; Bazhenova, L.; Hirashima, T.; Rukazenkov, Y.; Cantarini, M.; Mann, H.; Ramalingam, S. S.; Mitsudomi, T.; Jaenne, P. A.; Goss, G. D. 分享 收藏
Phase III trial of afatinib vs erlotinib in patients with squamous cell carcinoma (SCC) of the lung (LUX-Lung 8): EGFR molecular aberrations and survival outcomes Goss, G. D.; Felip, E.; Cobo, M.; Lu, S.; Syrigos, K.; Li, K. W.; Zhou, C.; Park, K.; Solca, F.; Kraemer, N.; Chand, V. K.; Soria, J. C. 分享 收藏
AZD9291 in pre-treated patients with T790M positive advanced non-small cell lung cancer (NSCLC): Pooled analysis from two Phase II studies Goss, G. D.; Yang, J. C. H.; Ahn, M. J.; Tsai, C. M.; Bazhenova, L.; Sequist, L. V.; Ramalingam, S. S.; Shepherd, F. A.; Ghiorghiu, S.; Cantarini, M.; Mann, H.; Mitsudomi, T.; Jaenne, P. A. 分享 收藏
A randomized phase II study of ganetespib, a heat shock protein 90 inhibitor, in combination with docetaxel in second-line therapy of advanced non-small cell lung cancer (GALAXY-1) Ramalingam, S.; Goss, G.; Rosell, R.; Schmid-Bindert, G.; Zaric, B.; Andric, Z.; Bondarenko, I.; Komov, D.; Ceric, T.; Khuri, F.; Samarzija, M.; Felip, E.; Ciuleanu, T.; Hirsh, V.; Wehler, T.; Spicer, J.; Salgia, R.; Shapiro, G.; Sheldon, E.; Teofilovici, F.; Vukovic, V.; Fennell, D. 分享 收藏
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