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Somatic PIK3R1 mutations in the iSH2 domain are accessible to PI3Kα inhibition 体细胞PIK3R1基因在iSH2结构域的突变可被PI3Kα抑制。 Morin, Gabriel; Garneau, Alexandre P.; Bouzakher, Nabiha; Segot, Louise; Fraissenon, Antoine; Blondel, Amelie; Petit, Florence; Chopinet, Caroline; Mayeux, Franck; Fayoux, Pierre; Dompmartin, Anne; Bodemer, Christine; Balducci, Estelle; Kaltenbach, Sophie; Villarese, Patrick; Asnafi, Vahid; Legendre, Christophe; Broissand, Christine; Fraitag, Sylvie; Quelin, Chloe; Goudin, Nicolas; Guibaud, Laurent; Canaud, Guillaume 分享 收藏
Severe inflammation and lineage skewing are associated with poor engraftment of engineered hematopoietic stem cells in patients with sickle cell disease 严重炎症和谱系偏移与 sickle cell disease 患者中工程化造血干细胞的植入不良相关。 Sobrino, Steicy; Joseph, Laure; Magrin, Elisa; Chalumeau, Anne; Hebert, Nicolas; Corsia, Alice; Denis, Adeline; Roudaut, Cecile; Aussel, Clotilde; Leblanc, Olivia; Brusson, Megane; Felix, Tristan; Diana, Jean-Sebastien; Petrichenko, Angelina; El Etri, Jana; Godard, Auria; Tibi, Eden; Manceau, Sandra; Treluyer, Jean Marc; Mavilio, Fulvio; Bushman, Frederic D.; Marcais, Ambroise; Castelle, Martin; Neven, Benedicte; Hermine, Olivier; Renolleau, Sylvain; Magnani, Alessandra; Asnafi, Vahid; El Nemer, Wassim; Bartolucci, Pablo; Six, Emmanuelle; Semeraro, Michaela; Miccio, Annarita 分享 收藏
Clinical and molecular landscape of paediatric cerebral and spinal cavernous malformations 儿童脑和脊髓海绵状血管畸形临床与分子景观 Benichi, Sandro; Balducci, Estelle; Benzakoun, Joseph; Ghannam, Boulos; Attieh, Christian; Metais, Alice; Bourgeois, Marie; Guida, Lelio; Kaltenbach, Sophie; Tauziede-Espariat, Arnault; Riant, Florence; Villarese, Patrick; Lefevre, Coline; Roux, Charles-Joris; Puget, Stephanie; Naggara, Olivier; Oppenheim, Catherine; Nabbout, Rima; Boddaert, Nathalie; Beccaria, Kevin; Tournier-Lasserve, Elisabeth; Kossorotoff, Manoelle; Varlet, Pascale; Asnafi, Vahid; Canaud, Guillaume; Blauwblomme, Thomas 分享 收藏
How to Administer Pegaspargase during Induction Treatment of Acute Lymphoblastic Leukemia in Children and Adolescents? Results of the Caall-F01, a Multicentre Randomized Clinical Trial from the French Pediatric Cancer Society (SFCE) 如何在儿童和青少年急性淋巴细胞白血病的诱导治疗期间使用Pegaspargase？Caall-F01研究结果，一项来自法国儿科肿瘤学会（SFCE）的多中心随机临床试验。 Strullu, Marion; Petit, Arnaud; Halfon-Domenech, Carine; Ray-Lunven, Anne-France; Saultier, Paul; Abou Chahla, Wadih; Ducassou, Stephane; Pasquet, Marlene; Thomas, Caroline; Pochon, Cecile; Gandemer, Virginie; Paillard, Catherine; Theron, Alexandre; Pluchart, Claire; Schneider, Pascale; Bodet, Damien; Pellier, Isabelle; Rohrlich, Pierre Simon; Jourdain, Anne-France; Simon, Pauline; Millot, Frederic; Carausu, Liana; Alla, Corinne Armari; Leglise, Camille; Kanold, Justyna; Desplantes, Claire; Thouvenin, Sandrine; Piguet, Christophe; Boissel, Nicolas; Cuccuini, Wendy; Asnafi, Vahid; Caye-Eude, Aurelie; Cave, Helene; Leverger, Guy; Benoist, Jean-Francois; Bertrand, Yves; Chevret, Sylvie; Baruchel, Andre 分享 收藏
Determinants of Isolated CNS Relapse in Adults with Philadelphia-Negative Acute Lymphoblastic Leukemia. from Graall-2005 to-2014 Trials 孤立性中枢神经系统复发的危险因素：来自Graall-2005至2014试验的研究。 Boissel, Nicolas; Lemasle, Emilie; Chantepie, Sylvain; Leguay, Thibaut; Orvain, Corentin; Huguet, Francoise; Hicheri, Yosr; Dhedin, Nathalie; Chevallier, Patrice; Balsat, Marie; Maury, Sebastien; Mathilde, Hunault-Berger; Bilger, Karin; Brissot, Eolia; Wittnebel, Sebastian; Guerder, Julie; Bonnet, Sarah; Turlure, Pascal; Huynh, Anne; Bories, Claire; Gregor, Michael; Mauz, Natacha; Aljijakli, Ahmad; Graux, Carlos; Chalandon, Yves; Ifrah, Norbert; Asnafi, Vahid; Clappier, Emmanuelle; Lheritier, Veronique; Dombret, Herve 分享 收藏
Ex Vivo Generation of Human T-Cell Progenitors from Cord Blood CD34+Cells Can Accelerate Immune Reconstitution after Umbilical Cord Blood Transplantation in Adult Patient with Hematologic Malignancies 离体条件下由脐带血CD34+细胞生成人T细胞祖细胞，可加速接受造血恶性肿瘤治疗成人患者进行脐带血移植后的免疫重建 Forcade, Edouard; Huynh, Anne; Magrin, Elisa; Diana, Jean-Sebastien; Schwartz, Eden; Aussel, Clotilde; Gabrion, Aurelie; Maulet, Axelle; Girardot, Alice; Ternaux, Brigitte; Tuchmann-Durand, Caroline; Baek, Jimni; Lhermitte, Ludovic; Touzart, Aurore; Asnafi, Vahid; Bouazza, Naim; Bauquet, Aurelie; Soheili, Shabi; Negre, Olivier; Andre, Isabelle; Treluyer, Jean-Marc; Hermine, Olivier; Cavazzana, Marina 分享 收藏
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Chloride deregulation and GABA depolarization in MTOR-related malformations of cortical development Bakouh, Naziha; Castano-Martin, Reyes; Metais, Alice; Dan, Emanuela Loredana; Balducci, Estelle; Chhuon, Cerina; Lepicka, Joanna; Barcia, Giulia; Losito, Emma; Lourdel, Stephane; Planelles, Gabrielle; Muresan, Raul C.; Moca, Vasile Vlad; Kaminska, Anna; Bourgeois, Marie; Chemaly, Nicole; Rguez, Yasmine; Auvin, Stephane; Huberfeld, Gilles; Varlet, Pascale; Asnafi, Vahid; Guerrera, Ida Chiara; Kabashi, Edor; Nabbout, Rima; Ciura, Sorana; Blauwblomme, Thomas 分享 收藏
Sotorasib for Vascular Malformations Associated with KRAS G12C Mutation Fraissenon, Antoine; Bayard, Charles; Morin, Gabriel; Benichi, Sandro; Hoguin, Clement; Protic, Sanela; Zerbib, Lola; Ladraa, Sophia; Firpion, Marina; Blauwblomme, Thomas; Naggara, Olivier; Duruisseaux, Michael; Delous, Marion; Boitel, Clothilde; Bringuier, Pierre-Paul; Payen, Lea; Legendre, Christophe; Kaltenbach, Sophie; Balducci, Estelle; Villarese, Patrick; Asnafi, Vahid; Bisdorff, Annouk; Guibaud, Laurent; Canaud, Guillaume 分享 收藏
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Dependence on mitochondrial respiration of malignant T cells reveals a new therapeutic target for angioimmunoblastic T-cell lymphoma Krug, Adrien; Mhaidly, Rana; Tosolini, Marie; Mondragon, Laura; Tari, Gamze; Turtos, Adriana Martinez; Paul-Bellon, Rachel; Asnafi, Vahid; Marchetti, Sandrine; Di Mascio, Lea; Travert, Marion; Bost, Frederic; Bachy, Emmanuel; Arguello, Rafael J.; Fournie, Jean-Jacques; Gaulard, Philippe; Lemonnier, Francois; Ricci, Jean-Ehrland; Verhoeyen, Els 分享 收藏
Multimodal integration of clinic, pathology, and genomics for a rare diagnosis of EBV-positive primary mediastinal large B-cell lymphoma Thiebaut, Pierre-Alain; Isnard, Pierre; Couronne, Lucile; Kaltenbach, Sophie; Lepine, Charles; Sibon, David; Balducci, Estelle; Ruminy, Philippe; Badoual, Cecile; Briere, Josette; Hermine, Olivier; Asnafi, Vahid; Gaulard, Phillippe; Bruneau, Julie; Molina, Thierry Jo 分享 收藏
Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers that expand in IL-7R-STAT5B-driven neoplasms Sumaria, Nital; Fiala, Gina J.; Inacio, Daniel; Curado-Avelar, Marta; Cachucho, Ana; Pinheiro, Ruben; Wiesheu, Robert; Kimura, Shunsuke; Courtois, Lucien; Blankenhaus, Birte; Darrigues, Julie; Suske, Tobias; Almeida, Afonso R. M.; Minguet, Susana; Asnafi, Vahid; Lhermitte, Ludovic; Mullighan, Charles G.; Coffelt, Seth B.; Moriggl, Richard; Barata, Joao T.; Pennington, Daniel J.; Silva-Santos, Bruno 分享 收藏
Comprehensive Genetic Profiling Reveals Frequent Alterations of Driver Genes on the X Chromosome in Extranodal NK/T-cell Lymphoma Ito, Yuta; Marouf, Amira; Kogure, Yasunori; Koya, Junji; Lievin, Raphael; Bruneau, Julie; Tabata, Mariko; Saito, Yuki; Shingaki, Sumito; Yuasa, Mitsuhiro; Yamaguchi, Kentaro; Murakami, Koichi; Weil, Robert; Vavasseur, Manon; Andrieu, Guillaume P.; Latiri, Mehdi; Veleanu, Layla; Dussiot, Michael; Andre, Isabelle; Joshi, Akshay; Lagresle-Peyrou, Chantal; Magerus, Aude; Chaubard, Sammara; Lavergne, David; Bachy, Emmanuel; Brunet, Erika; Fataccioli, Virginie; Brouzes, Chantal; Laurent, Camille; de Leval, Laurence; Traverse-Glehen, Alexandra; Bossard, Celine; Parrens, Marie; Meignin, Veronique; Philippe, Laure; Rossignol, Julien; Suarez, Felipe; Michot, Jean-Marie; Tournilhac, Olivier; Damaj, Gandhi; Lemonnier, Francois; Bole-Feysot, Christine; Nitschke, Patrick; Tesson, Bruno; Laurent, Cecile; Molina, Thierry; Asnafi, Vahid; Watatani, Yosaku; Chiba, Kenichi; Okada, Ai; Shiraishi, Yuichi; Tsukita, Sachiko; Izutsu, Koji; Miyoshi, Hiroaki; Ohshima, Koichi; Sakata, Seiji; Dobashi, Akito; Takeuchi, Kengo; Sanada, Masashi; Gaulard, Philippe; Jaccard, Arnaud; Ogawa, Seishi; Hermine, Olivier; Kataoka, Keisuke; Couronne, Lucile 分享 收藏
Hemifacial myohyperplasia is due to somatic muscular PIK3CA gain-of-function mutations and responds to pharmacological inhibition Bayard, Charles; Segna, Eleonora; Taverne, Maxime; Fraissenon, Antoine; Hennocq, Quentin; Periou, Baptiste; Zerbib, Lola; Ladraa, Sophia; Chapelle, Celia; Hoguin, Clement; Kaltenbach, Sophie; Villarese, Patrick; Asnafi, Vahid; Broissand, Christine; Nemazanyy, Ivan; Autret, Gwennhael; Goudin, Nicolas; Legendre, Christophe; Authier, Francois-Jerome; Viel, Thomas; Tavitian, Bertrand; Gitiaux, Cyril; Fraitag, Sylvie; Duong, Jean-Paul; Delcros, Clarisse; Sergent, Bernard; Picard, Arnaud; Dussiot, Michael; Guibaud, Laurent; Khonsari, Roman; Canaud, Guillaume 分享 收藏
KIR3DL2 also represents a novel therapeutic target in non-cutaneous aggressive systemic peripheral T-cell lymphomas Ortonne, Nicolas; Cheminant, Morgane; Bruneau, Julie; Carras, Sylvain; Parinet, Vincent; Pelletier, Laura; Lacroix, Laetitia; Giustiniani, Jerome; Lhermitte, Ludovic; Asnafi, Vahid; Battistella, Maxime; Lemonnier, Francois; De Leval, Laurence; Sicard, Helene; Bonnafous, Cecile; Gauthier, Laurent; Genestier, Laurent; Caruso, Stefano; Gaulard, Philippe; Hermine, Olivier 分享 收藏
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