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J

John P. Murad

USC
H指数:15
被引数:1,693

个人简介

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工作经历

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Solid tumour CAR-T cells engineered with fusion proteins targeting PD-L1 for localized IL-12 delivery

靶向PD-L1的融合蛋白工程化改造的实体瘤CAR-T细胞，用于局部IL-12递送

Nature Biomedical Engineering
IF26.6
2025-10-010
OAAI
John P. Murad; Lea Christian; Reginaldo Rosa; Yuwei Ren; Alyssa J. Buckley; Eric Hee Jun Lee; Lupita S. Lopez; Anthony K. Park; Jason Yang; Yukiko Yamaguchi; Candi Trac; Lauren N. Adkins; Wen-Chung Chang; Catalina Martinez; Carl H. June; Stephen J. Forman; Jun Ishihara; John K. Lee; Lawrence A. Stern; Saul J. Priceman
PSCA-CAR T cell therapy in metastatic castration-resistant prostate cancer: a phase 1 trial
NATURE MEDICINE
IF50
2024-06-1215
OAAI
Dorff, Tanya B.; Blanchard, M. Suzette; Adkins, Lauren N.; Luebbert, Laura; Leggett, Neena; Shishido, Stephanie N.; Macias, Alan; Del Real, Marissa M.; Dhapola, Gaurav; Egelston, Colt; Murad, John P.; Rosa, Reginaldo; Paul, Jinny; Chaudhry, Ammar; Martirosyan, Hripsime; Gerdts, Ethan; Wagner, Jamie R.; Stiller, Tracey; Tilakawardane, Dileshni; Pal, Sumanta; Martinez, Catalina; Reiter, Robert E.; Budde, Lihua E.; D'Apuzzo, Massimo; Kuhn, Peter; Pachter, Lior; Forman, Stephen J.; Priceman, Saul J.
Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting

CAR T细胞中的抗原依赖性IL-12信号传导促进区域至全身性疾病靶向

NATURE COMMUNICATIONS
IF15.7
2023-08-0723
OAAI
Lee, Eric Hee Jun; Murad, John P.; Christian, Lea; Gibson, Jackson; Yamaguchi, Yukiko; Cullen, Cody; Gumber, Diana; Park, Anthony K.; Young, Cari; Monroy, Isabel; Yang, Jason; Stern, Lawrence A.; Adkins, Lauren N.; Dhapola, Gaurav; Gittins, Brenna; Chang, Wen-Chung; Martinez, Catalina; Woo, Yanghee; Cristea, Mihaela; Rodriguez-Rodriguez, Lorna; Ishihara, Jun; Lee, John K.; Forman, Stephen J.; Wang, Leo D.; Priceman, Saul J.
Pre-conditioning modifies the TME to enhance solid tumor CAR T cell efficacy and endogenous protective immunity

预处理修饰TME以增强实体瘤CAR T细胞功效和内源性保护性免疫

MOLECULAR THERAPY
IF12
2021-07-0162
OAAI
Murad, John P.; Tilakawardane, Dileshni; Park, Anthony K.; Lopez, Lupita S.; Young, Cari A.; Gibson, Jackson; Yamaguchi, Yukiko; Lee, Hee Jun; Kennewick, Kelly T.; Gittins, Brenna J.; Chang, Wen-Chung; Tran, Chau P.; Martinez, Catalina; Wu, Anna M.; Reiter, Robert E.; Dorff, Tanya B.; Forman, Stephen J.; Priceman, Saul J.
Regional Delivery of Chimeric Antigen Receptor-Engineered T Cells Effectively Targets HER2 thorn Breast Cancer Metastasis to the Brain

嵌合抗原受体工程化T细胞的区域递送有效靶向HER2刺乳腺癌转移至大脑

CLINICAL CANCER RESEARCH
IF10.2
2018-01-02250
OAAI
Priceman, Saul J.; Tilakawardane, Dileshni; Jeang, Brook; Aguilar, Brenda; Murad, John P.; Park, Anthony K.; Chang, Wen-Chung; Ostberg, Julie R.; Neman, Josh; Jandial, Rahul; Portnow, Jana; Forman, Stephen J.; Brown, Christine E.
Co-stimulatory signaling determines tumor antigen sensitivity and persistence of CAR T cells targeting PSCA plus metastatic prostate cancer

共刺激信号决定肿瘤抗原敏感性和靶向PSCA加转移性前列腺癌的CAR T细胞的持久性

ONCOIMMUNOLOGY
IF6.3
2017-10-16129
OAAI
Priceman, Saul J.; Gerdts, Ethan A.; Tilakawardane, Dileshni; Kennewick, Kelly T.; Murad, John P.; Park, Anthony K.; Jeang, Brook; Yamaguchi, Yukiko; Yang, Xin; Urak, Ryan; Weng, Lihong; Chang, Wen-Chung; Wright, Sarah; Pal, Sumanta; Reiter, Robert E.; Wu, Anna M.; Brown, Christine E.; Forman, Stephen J.

研究方向

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S
Saul J. Priceman
H 指数:34论文数:204被引数:8,791
S
Stephen J. Forman
H 指数:127论文数:1,786被引数:5.9万
W
Wen-Chung Chang
H 指数:23论文数:72被引数:2,961
A
Anthony K. Park
H 指数:14论文数:46被引数:1,291
Y
Yukiko Yamaguchi
H 指数:15论文数:57被引数:1,534
D
Dileshni Tilakawardane
H 指数:7论文数:33被引数:753
J
Jason Yang
H 指数:29论文数:139被引数:3,726
L
Lea Christian
H 指数:4论文数:11被引数:135
L
Lupita S. Lopez
H 指数:4论文数:13被引数:251
C
Catalina Martínez
H 指数:12论文数:33被引数:1,180