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Mucosal vaccines with STING-agonist liposomal formulations inhibit RSV (respiratory syncytial virus) replication in cotton rats 含有STING激动剂脂质体制剂的黏膜疫苗可抑制仓鼠呼吸道合胞病毒（RSV）的复制 Sefat, K. M. Samiur Rahman; Kulkarni, Rohan; Trinh, Jason; Leekha, Ankita; Kumar, Monish; Wu, Haoran; McBride, Trevor; Aideyan, Letisha; Avadhanula, Vasanthi; Piedra, Pedro A.; Louie, Stacey M.; Varadarajan, Navin 分享 收藏
Multi-antigen intranasal vaccine protects against challenge with sarbecoviruses and prevents transmission in hamsters Leekha, Ankita; Saeedi, Arash; Sefat, K. M. Samiur Rahman; Kumar, Monish; Martinez-Paniagua, Melisa; Damian, Adrian; Kulkarni, Rohan; Reichel, Kate; Rezvan, Ali; Masoumi, Shalaleh; Liu, Xinli; Cooper, Laurence J. N.; Sebastian, Manu; Sands, Courtney M.; Das, Vallabh E.; Patel, Nimesh B.; Hurst, Brett; Varadarajan, Navin 分享 收藏
CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ζ/ZAP70 Signaling Axis Acharya, Sunil; Basar, Rafet; Daher, May; Rafei, Hind; Li, Ping; Uprety, Nadima; Ensley, Emily; Shanley, Mayra; Kumar, Bijender; Banerjee, Pinaki P.; Melo Garcia, Luciana; Lin, Paul; Mohanty, Vakul; Kim, Kun H.; Jiang, Xianli; Pan, Yuchen; Li, Ye; Liu, Bin; Cortes, Ana K. Nunez; Zhang, Chenyu; Fathi, Mohsen; Rezvan, Ali; Montalvo, Melisa J.; Cha, Sophia L.; Reyes-Silva, Francia; Shrestha, Rejeena; Guo, Xingliang; Kundu, Kiran; Biederstadt, Alexander; Muniz-Feliciano, Luis; Deyter, Gary M.; Kaplan, Mecit; Jiang, Xin R.; Liu, Enli; Jain, Antrix; Roszik, Janos; Fowlkes, Natalie W.; Solis Soto, Luisa M.; Raso, Maria G.; Khoury, Joseph D.; Lin, Pei; Vega, Francisco; Varadarajan, Navin; Chen, Ken; Marin, David; Shpall, Elizabeth J.; Rezvani, Katayoun 分享 收藏
An intranasal nanoparticle STING agonist protects against respiratory viruses in animal models Leekha, Ankita; Saeedi, Arash; Kumar, Monish; Sefat, K. M. Samiur Rahman; Martinez-Paniagua, Melisa; Meng, Hui; Fathi, Mohsen; Kulkarni, Rohan; Reichel, Kate; Biswas, Sujit; Tsitoura, Daphne; Liu, Xinli; Cooper, Laurence J. N.; Sands, Courtney M.; Das, Vallabh E.; Sebastian, Manu; Hurst, Brett L.; Varadarajan, Navin 分享 收藏
Identification of a clinically efficacious CAR T cell subset in diffuse large B cell lymphoma by dynamic multidimensional single-cell profiling (May, 10.1038/s43018-024-00768-3, 2024) Rezvan, Ali; Romain, Gabrielle; Fathi, Mohsen; Heeke, Darren; Martinez-Paniagua, Melisa; An, Xingyue; Bandey, Irfan N.; Montalvo, Melisa J.; Adolacion, Jay R. T.; Saeedi, Arash; Sadeghi, Fatemeh; Fousek, Kristen; Puebla-Osorio, Nahum; Cooper, Laurence J. N.; Bernatchez, Chantale; Singh, Harjeet; Ahmed, Nabil; Mattie, Mike; Bot, Adrian; Neelapu, Sattva; Varadarajan, Navin 分享 收藏
Identification of a clinically efficacious CAR T cell subset in diffuse large B cell lymphoma by dynamic multidimensional single-cell profiling 通过动态多维单细胞分析鉴定弥漫性大b细胞淋巴瘤中临床有效的CAR T细胞亚群 Rezvan, Ali; Romain, Gabrielle; Fathi, Mohsen; Heeke, Darren; Martinez-Paniagua, Melisa; An, Xingyue; Bandey, Irfan N.; Montalvo, Melisa J.; Adolacion, Jay R. T.; Saeedi, Arash; Sadeghi, Fatemeh; Fousek, Kristen; Puebla-Osorio, Nahum; Cooper, Laurence J. N.; Bernatchez, Chantale; Singh, Harjeet; Ahmed, Nabil; Mattie, Mike; Bot, Adrian; Neelapu, Sattva; Varadarajan, Navin 分享 收藏
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Decoding the mechanisms of chimeric antigen receptor (CAR) T cell-mediated killing of tumors: insights from granzyme and Fas inhibition Montalvo, Melisa J.; Bandey, Irfan N.; Rezvan, Ali; Wu, Kwan-Ling; Saeedi, Arash; Kulkarni, Rohan; Li, Yongshuai; An, Xingyue; Sefat, K. M. Samiur Rahman; Varadarajan, Navin 分享 收藏
KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape (vol 28, pg 2133, 2022) Li, Ye; Basar, Rafet; Wang, Guohui; Liu, Enli; Moyes, Judy S.; Li, Li; Kerbauy, Lucila N.; Uprety, Nadima; Fathi, Mohsen; Rezvan, Ali; Banerjee, Pinaki P.; Muniz-Feliciano, Luis; Laskowski, Tamara J.; Ensley, Emily; Daher, May; Shanley, Mayra; Mendt, Mayela; Acharya, Sunil; Liu, Bin; Biederstaedt, Alexander; Rafei, Hind; Guo, Xingliang; Melo Garcia, Luciana; Lin, Paul; Ang, Sonny; Marin, David; Chen, Ken; Bover, Laura; Champlin, Richard E.; Varadarajan, Navin; Shpall, Elizabeth J.; Rezvani, Katayoun 分享 收藏
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KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape Li, Ye; Basar, Rafet; Wang, Guohui; Liu, Enli; Moyes, Judy S.; Li, Li; Kerbauy, Lucila N.; Uprety, Nadima; Fathi, Mohsen; Rezvan, Ali; Banerjee, Pinaki P.; Muniz-Feliciano, Luis; Laskowski, Tamara J.; Ensley, Emily; Daher, May; Shanley, Mayra; Mendt, Mayela; Acharya, Sunil; Liu, Bin; Biederstadt, Alexander; Rafei, Hind; Guo, Xingliang; Melo Garcia, Luciana; Lin, Paul; Ang, Sonny; Marin, David; Chen, Ken; Bover, Laura; Champlin, Richard E.; Varadarajan, Navin; Shpall, Elizabeth J.; Rezvani, Katayoun 分享 收藏
Multidimensional single-cell analysis identifies a role for CD2-CD58 interactions in clinical antitumor T cell responses 多维单细胞分析确定了CD2-CD58相互作用在临床抗肿瘤T细胞反应中的作用 Romain, Gabrielle; Strati, Paolo; Rezvan, Ali; Fathi, Mohsen; Bandey, Irfan N.; Adolacion, Jay R. T.; Heeke, Darren; Liadi, Ivan; Marques-Piubelli, Mario L.; Solis, Luisa M.; Mahendra, Ankit; Vega, Francisco; Cooper, Laurence J. N.; Singh, Harjeet; Mattie, Mike; Bot, Adrian; Neelapu, Sattva S.; Varadarajan, Navin 分享 收藏
Multiomic dynamic single-cell profiling of CAR T cell populations associated with efficacy Rezvan, Ali; Romain, Gabrielle; Fathi, Mohsen; Heeke, Darren; Martinez-Paniagua, Melisa; An, Xingyue; Bandey, Irfan N.; Liadi, Ivan; Cooper, Laurence J. N.; Singh, Harjeet; Bot, Adrian; Neelapu, Sattva; Varadarajan, Navin 分享 收藏
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THE PANORAMA OF TUMOR INTRINSIC IMMUNE REGULATORS EXHIBITED BY GENOME-WIDE CRPISR IMMUNE SCREEN INTEGRATED WITH COMPREHENSIVE CLINICAL DATASET ANALYSIS Hou, Jiakai; Wang, Yunfei; Shi, Leilei; Chen, Yuan; Xu, Chunyu; Saeedi, Arash; Pan, Ke; Bohat, Ritu; Egan, Nicholas; McKenzie, Jodi; Mbofung, Rina; Williams, Leila; Yang, Zhenhuang; Sun, Ming; Liang, Xiaofang; Ahnert, Jordi Rodon; Varadarajan, Navin; Yee, Cassian; Chen, Yiwen; Hwu, Patrick; Peng, Weiyi 分享 收藏
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CD8+ T cells inhibit metastasis and CXCL4 regulates its function CD8 T细胞抑制转移和CXCL4调节其功能 Joseph, Robiya; Soundararajan, Rama; Vasaikar, Suhas; Yang, Fei; Allton, Kendra L.; Tian, Lin; den Hollander, Petra; Isgandarova, Sevinj; Haemmerle, Monika; Mino, Barbara; Zhou, Tieling; Shin, Crystal; Martinez-Paniagua, Melisa; Sahin, Aysegul A.; Rodriguez-Canales, Jaime; Gelovani, Juri; Chang, Jeffrey T.; Acharya, Ghanashyam; Sood, Anil K.; Wistuba, Ignacio I.; Gibbons, Don L.; Solis, Luisa M.; Barton, Michelle C.; Varadarajan, Navin; Rosen, Jeffrey M.; Zhang, Xiang H.; Mani, Sendurai A. 分享 收藏
Designed improvement to T-cell immunotherapy by multidimensional single cell profiling Bandey, Irfan N.; Adolacion, Jay R. T.; Romain, Gabrielle; Paniagua, Melisa Martinez; An, Xingyue; Saeedi, Arash; Liadi, Ivan; You, Zheng; Rajanayake, Rasindu B.; Hwu, Patrick; Singh, Harjeet; Cooper, Laurence J. N.; Varadarajan, Navin 分享 收藏
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