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E

Elena Sotillo

Stanford Cancer Institute
H指数:39
被引数:8,121

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Quantitative surfaceome profiling of high-risk medulloblastoma prioritizes the oncofetal antigen GPC2 for potent CAR-T cell therapy

高风险髓母细胞瘤的定量表面组分析优先考虑癌胚抗原GPC2用于有效的CAR-T细胞疗法

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Usta, Diren; Gwynne, William; Suk, Yujin; Chen, Yiyun; Radosevic, Molly T.; Chernova, Daria; Delaidelli, Alberto; Feng, Yushen; Nasajpour, Emon; Trissal, Maria C.; Poetschke, Rebecca D.; Dunham, Christopher; Labanie, Louai; Van Der Lugt, Jasper; Nierkens, Stefan; Filbin, Mariella G.; Petritsch, Claudia K.; Sorensen, Poul; Ryan, Katherine J.; Venugopal, Chitra; Sotillo, Elena; Mackall, Crystal L.; Singh, Sheila K.; Heitzeneder, Sabine
HUMANIZED ANTI-CAR ANTIBODIES AFFECT DURABLE RESPONSE TO GD2-CAR T-CELLS IN DIFFUSE MIDLINE GLIOMA

人源化抗CAR抗体影响弥漫性中线胶质瘤中GD2-CAR T细胞的持久应答

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Chen, Yiyun; Song, Kun-Wei; Huang, Ying-Wen; Iswari, Nadya; Desai, Moksha; Ehlinger, Zachary; Daghagh, Hossein; Reynolds, Kevin; Mahdi, Jasia; Majzner, Robbie; Richards, Becky; Kamens, Jennifer; Barsan, Valentin; Campen, Cynthia; Partap, Sonia; Madhav, Divya; Moon, Jennifer; Baggott, Christina; Fujimoto, Michelle; Li, Amy; Jariwala, Sneha; Mavroukakis, Sharon; Egeler, Emily; Jacobs, Ashley; Erickson, Courtney; Kaur, Aanchal Preet; Soundaranayagi, Smriti; Rietberg, Skyler; Schultz, Liora; Davis, Kara; Feldman, Steven; Heitzeneder, Sabine; Yamada-Hunter, Sean; Sotillo, Elena; Good, Zinaida; Sahaf, Bita; Monje, Michelle; Ramakrishna, Sneha; Mackall, Crystal
SINGLE-CELL LANDSCAPE OF B7H3-CAR T THERAPY IN GLIOMA: MECHANISMS OF RESISTANCE AND SIGNATURES OF LONG-TERM RESPONSE

单细胞景观揭示B7H3-CAR T疗法在胶质瘤中的抗药机制及长期应答特征

NEURO-ONCOLOGY
IF13.4
2025-11-010
PRE
Chen, Yiyun; Song, Kun-Wei; Desai, Moksha; Ehlinger, Zach; Daghagh, Hossein; Rietberg, Skyler; Feeney, Anne-Marie; Tanner, Kelly; Dyson, Kyle; Stockdale, Brian; Dhapola, Gaurav; Lohman, Claire; Patil, Sunita; Kuo, Adam; Good, Zinaida; Prabhu, Snehit; Kong, Katherine; Egeler, Emily; Beebe, Barbara; Carr, Casey; Mahdi, Jasia; Bertrand, Sophie; Iv, Michael; Threlkeld, Zachary; Charu, Vivek; Tunuguntla, Ramya; Therkelsen, Kate; Nagpal, Seema; Monje, Michelle; Scott, Brian; Li, Gordon; Lim, Michael; Sotillo, Elena; Sahaf, Bita; Ramakrishna, Sneha; Thomas, Reena; Mackall, Crystal
GLUT1 overexpression in CAR-T cells induces metabolic reprogramming and enhances potency

Car-t细胞中GLUT1过表达诱导代谢重编程并增强效力

NATURE COMMUNICATIONS
IF15.7
2024-10-061
OAAI
Guerrero, Justin A.; Klysz, Dorota D.; Chen, Yiyun; Malipatlolla, Meena; Lone, Jameel; Fowler, Carley; Stuani, Lucille; May, Audre; Bashti, Malek; Xu, Peng; Huang, Jing; Michael, Basil; Contrepois, Kevin; Dhingra, Shaurya; Fisher, Chris; Svensson, Katrin J.; Davis, Kara L.; Kasowski, Maya; Feldman, Steven A.; Sotillo, Elena; Mackall, Crystal L.
IKAROS mediates antigen escape following CD19-or CD22-targeted immunotherapies in r/r B-ALL
CANCER RESEARCH
IF16.6
2024-09-050
PRE
Domizi, Pablo; Sarno, Jolanda; Jager, Astraea; Merchant, Milton; Pacheco, Kaithlen; Yamada-Hunter, Sean; Rotiroti, Maria Caterina; Liu, Yuxuan; Baskar, Reema; Reynolds, Warren; Sworder, Brian; Sahaf, Bita; Bendall, Sean; Mullighan, Charles; Alizadeh, Ash; Leahy, Allison; Myers, Regina; Grupp, Stephan; Majzner, Robbie; Barrett, David; Sotillo, Elena; Davis, Kara
The cytokine Meteorin-like inhibits anti-tumor CD8+T cell responses by disrupting mitochondrial function

细胞因子类镍纹蛋白通过破坏线粒体功能抑制抗肿瘤CD8 T细胞反应

IMMUNITY
IF26.3
2024-08-011
PRE
Jackson, Christopher M.; Pant, Ayush; Dinalankara, Wikum; Choi, John; Jain, Aanchal; Nitta, Ryan; Yazigi, Eli; Saleh, Laura; Zhao, Liang; Nirschl, Thomas R.; Kochel, Christina M.; Bergsneider, Brandon Hwa-Lin; Routkevitch, Denis; Patel, Kisha; Cho, Kwang Bog; Tzeng, Stephany; Neshat, Sarah Y.; Kim, Young-Hoon; Smith, Barbara J.; Ramello, Maria Cecilia; Sotillo, Elena; Wang, Xinnan; Green, Jordan J.; Bettegowda, Chetan; Li, Gordon; Brem, Henry; Mackall, Crystal L.; Pardoll, Drew M.; Drake, Charles G.; Marchionni, Luigi; Lim, Michael
Enhancing pediatric access to cell and gene therapies

提高儿科获得细胞和基因疗法的机会

NATURE MEDICINE
IF50
2024-06-172
PRE
Mackall, Crystal L.; Bollard, Catherine M.; Goodman, Nancy; Carr, Casey; Gardner, Rebecca; Rouce, Rayne; Sotillo, Elena; Stoner, Rich; Urnov, Fyodor D.; Wayne, Alan S.; Park, Julie; Kohn, Donald B.
Engineered CD47 protects T cells for enhanced antitumour immunity

工程CD47保护T细胞增强抗肿瘤免疫

Nature
IF48.5
2024-05-150
OAAI
Sean A. Yamada-Hunter; Johanna Theruvath; Brianna J. McIntosh; Katherine A. Freitas; Frank Lin; Molly T. Radosevich; Amaury Leruste; Shaurya Dhingra; Naiara Martinez-Velez; Peng Xu; Jing Huang; Alberto Delaidelli; Moksha H. Desai; Zinaida Good; Roel Polak; Audre May; Louai Labanieh; Jeremy Bjelajac; Tara Murty; Zach Ehlinger; Christopher W. Mount; Yiyun Chen; Sabine Heitzeneder; Kristopher D. Marjon; Allison Banuelos; Omair Khan; Savannah L. Wasserman; Jay Y. Spiegel; Sebastian Fernandez-Pol; Calvin J. Kuo; Poul H. Sorensen; Michelle Monje; Robbie G. Majzner; Irving L. Weissman; Bita Sahaf; Elena Sotillo; Jennifer R. Cochran; Crystal L. Mackall
Publisher Correction: FOXO1 is a master regulator of memory programming in CAR T cells

出版更正：FOXO1是CAR T细胞记忆编程的主调控因子

Nature
IF48.5
2024-04-230
OAAI
Alexander E. Doan; Katherine P. Mueller; Andy Y. Chen; Geoffrey T. Rouin; Yingshi Chen; Bence Daniel; John Lattin; Martina Markovska; Brett Mozarsky; Jose Arias-Umana; Robert Hapke; In-Young Jung; Alice Wang; Peng Xu; Dorota Klysz; Gabrielle Zuern; Malek Bashti; Patrick J. Quinn; Zhuang Miao; Katalin Sandor; Wenxi Zhang; Gregory M. Chen; Faith Ryu; Meghan Logun; Junior Hall; Kai Tan; Stephan A. Grupp; Susan E. McClory; Caleb A. Lareau; Joseph A. Fraietta; Elena Sotillo; Ansuman T. Satpathy; Crystal L. Mackall; Evan W. Weber
FOXO1 is a master regulator of memory programming in CAR T cells
Nature
IF48.5
2024-04-100
OAAI
Alexander E. Doan; Katherine P. Mueller; Andy Y. Chen; Geoffrey T. Rouin; Yingshi Chen; Bence Daniel; John Lattin; Martina Markovska; Brett Mozarsky; Jose Arias-Umana; Robert Hapke; In-Young Jung; Alice Wang; Peng Xu; Dorota Klysz; Gabrielle Zuern; Malek Bashti; Patrick J. Quinn; Zhuang Miao; Katalin Sandor; Wenxi Zhang; Gregory M. Chen; Faith Ryu; Meghan Logun; Junior Hall; Kai Tan; Stephan A. Grupp; Susan E. McClory; Caleb A. Lareau; Joseph A. Fraietta; Elena Sotillo; Ansuman T. Satpathy; Crystal L. Mackall; Evan W. Weber
Lineage tracing defines responding CAR T cells in patients with B cell malignancies
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Good, Zinaida; Hamilton, Mark P.; Spiegel, Jay Y.; Desai, Moksha H.; Ehlinger, Zachary J.; Quinn, Patrick J.; Chen, Yiyun; Prabhu, Snehit; Chiou, Shin-Heng; Kurra, Sreevidya; Yang, Eric; Ozawa, Michael G.; Frank, Matthew J.; Muffly, Lori; Claire, Gursharan K.; Bharadwaj, Sushma; Dahiya, Saurabh; Kong, Katherine A.; Davis, Mark M.; Plevritis, Sylvia K.; Sotillo, Elena; Sahaf, Bita; Miklos, David B.; Mackall, Crystal L.
Inosine endows CAR T cells with features of increased stemness and anti-tumor potency
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Klysz, Dorota; Freitas, Katie; Malipatlolla, Meena; Maier, Stefanie; Fowler, Carley; Labanieh, Louai; Stuani, Lucille; Daniel, Bence; Sandor, Katalin; Xu, Peng; Huang, Jing; Leruste, Amaury; Keerthi, Vimal; Gkitsas, Nikolaos; Patel, Shabnum; Arredondo-Guerrero, Justin; Fisher, Chris; Asano, Kyle; Patel, Sunny; Satpathy, Ansuman; Davis, Kara; Sotillo, Elena; Feldman, Steven; Mackall, Crystal
Immune determinants of CAR-T expansion in solid tumor patients receiving GD2 CAR-T cell therapy
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Murty, Tara; Kaczanowska, Sabina; Alimadadi, Ahmad; Contreras, Cristina; Duault, Caroline; Balasubrahmanyan, Priyanka; Reynolds, Warren; Gutierrez, Norma; Baskar, Reema; Wu, Catherine; Michor, Franziska; Altreuter, Jennifer; Liu, Yang; Jhaveri, Aashna; Duong, Vandon; Anbunathan, Hima; Moravec, Radim; Hong, Joyce; Biswas, Roshni; Van Nostrand, Stephen; Lindsay, James; Pichavant, Mina; Sotillo, Elena; Sahaf, Bita; Bendall, Sean; Maecker, Holden; Highfill, Steven; Stroncek, David; Merchant, Melinda; Glod, John; Hedrick, Catherine; Mackall, Crystal; Ramakrishna, Sneha; Kaplan, Rosandra
Co-opting signalling molecules enables logic-gated control of CAR T cells
Nature
IF48.5
2023-03-080
PRE
Aidan M. Tousley; Maria Caterina Rotiroti; Louai Labanieh; Lea Wenting Rysavy; Won-Ju Kim; Caleb Lareau; Elena Sotillo; Evan W. Weber; Skyler P. Rietberg; Guillermo Nicolas Dalton; Yajie Yin; Dorota Klysz; Peng Xu; Eva L. de la Serna; Alexander R. Dunn; Ansuman T. Satpathy; Crystal L. Mackall; Robbie G. Majzner

研究方向

暂未获取到该数据
C
Crystal L. Mackall
H 指数:74论文数:341被引数:2.5万
C
Crystal L. Mackall
H 指数:71论文数:489被引数:2.5万
R
Robbie G. Majzner
H 指数:38论文数:240被引数:1.2万
A
Ansuman T. Satpathy
H 指数:75论文数:322被引数:2.8万
S
Sabine Heitzeneder
H 指数:13论文数:47被引数:3,449
A
Andrei Thomas‐Tikhonenko
H 指数:0论文数:3被引数:17
X
Xavier Graña
H 指数:35论文数:143被引数:5,112
D
Dorota D. Klysz
H 指数:17论文数:78被引数:3,205
B
Bita Sahaf
H 指数:38论文数:217被引数:6,995
A
Andrei Thomas‐Tikhonenko
H 指数:43论文数:216被引数:1.0万