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A

Arnd Kleyer

Charite University Medical Center Berlin
H指数:47
被引数:9,446

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CD19 CAR T cell therapy for treatment-refractory seropositive rheumatoid arthritis: a phase 1 trial

CD19 CAR T细胞疗法治疗难治性血清阳性类风湿关节炎：一项1期临床试验

Nature Medicine
IF50
2026-08-270
PRE
Fredrik N. Albach; Marie C. Rehm; Marie Luise Hütter-Krönke; Thanh Hang Le; Julia M. Giezen; Murat Torgutalp; Arne Sattler; Ioanna Minopoulou; Robert Biesen; Edgar Wiebe; Vincent Casteleyn; Thorben Witte; Christian Furth; Jan Zernicke; Melanie Nuesch Germano; Johan Verhagen; Artur Wilhelm; Maria Dzamukova; Klaus Engel; Simon Schallenberg; Aimo Kannt; Nicole Ziegler; Michaela Fehringer; Udo Schneider; Nadine Unterwalder; Mark Beling; Alexander Pfeil; Elpida Phithak; Martin Krusche; Olaf Penack; Tobias Alexander; Werner Stenzel; Manfred Wuhrer; Kamran Movassaghi; Thomas Dörner; Eicke Latz; Thomas Vogl; Antonia Busse; Georg Schett; Hans Ulrich Scherer; Rene E. M. Toes; Arnd Kleyer; Ulrich Keller; Lars Bullinger; David Simon; Gerhard Krönke
Effect of apremilast on entheseal bone damage in psoriasis patients at risk of developing psoriatic arthritis - data from the prospective, interventional EPOS study

阿普米拉斯特对处于银屑病关节炎发展风险中的银屑病患者附着点骨骼损伤的影响——来自前瞻性、干预性EPOS研究的数据

ARTHRITIS RESEARCH & THERAPY
IF4.6
2026-08-080
OAAI
David Simon; Ioanna Minopoulou; Sara Bayat; Louis Schuster; Koray Tascilar; Frank Roemer; Melek Yalcin Mutlu; Jürgen Rech; Dagmar Werner; Gerhard Krönke; Filippo Fagni; Michael Sticherling; Georg Schett; Arnd Kleyer
mRNA-based CAR T cell engineering: Unmodified mRNA enables high CAR expression without innate immune activation in T cells

mRNA介导的CAR T细胞工程：未经修饰的mRNA能够在不激活T细胞固有免疫的情况下实现高CAR表达

Molecular Therapy Nucleic Acids
IF6.1
2026-01-050
OAAI
Nourhan Kahwaji; Niklas Kotzian; Jasmin Melissa Prinz; Yaolin Pu; Jonas Kath; Samira Picht; Anna Luisa Hiller; Antonia Klaas; Charlotte Maeve Dunne; Michael Launspach; Andriko Palmowski; Arnd Kleyer; David Nils Simon; Dimitrios Laurin Wagner; Chantal Pichon; Gerhard Krönke; Michael Schmueck-Henneresse; Hans-Dieter Volk; Manfred Gossen; Norman Michael Drzeniek
Disease-associated brain activation predicts clinical response to TNF inhibition in rheumatoid arthritis (PreCePra): a randomised, multicentre, double-blind, placebo-controlled phase 3 study

疾病相关脑激活预测类风湿关节炎中TNF抑制的临床反应（PreCePra）：一项随机、多中心、双盲、安慰剂对照的III期研究

lancet rheumatology
IF0
2025-06-230
OAAI
Andreas Hess; Koray Tascilar; Hanna M Schenker; Laura Konerth; Verena Schönau; Marina Sergeeva; Silke Kreitz; Jutta Prade; Sandra Strobelt; Mageshwar Selvakumar; Arnd Kleyer; Matthias Englbrecht; Axel J Hueber; Mario M Zaiss; Eugen Feist; Gerd R Burmester; Reinhard E Voll; Stephanie Finzel; Christoph Baerwald; Julie Rösch; Frank Behrens; Michaela Koehm; Jose Antonio P da Silva; Nemanja Damjanov; Arnd Dörfler; Georg Schett; Jürgen Rech
EULAR/American College of Rheumatology Risk Stratification Criteria for Development of Rheumatoid Arthritis in the Risk Stage of Arthralgia

EULAR/美国风湿病学会针对关节痛风险阶段发展为类风湿关节炎的风险分层标准

ARTHRITIS & RHEUMATOLOGY
IF10.9
2025-05-080
PRE
van Steenbergen, Hanna W.; Doornkamp, Frank; Alivernini, Stefano; Backlund, John; Codreanu, Catalin; Cohen, Stanley B.; Combe, Bernard; Cope, Andrew P.; Deane, Kevin D.; England, Bryant R.; Falahee, Marie; de Jong, Pascal H. P.; Kleyer, Arnd; Lacaille, Diane; Maat, Bertha; Mankia, Kulveer; van Mulligen, Elise; Nagy, Gyoergy; O'Neil, Liam J.; Rodamaker, Linda; Sahbudin, Ilfita; van Schaardenburg, Dirkjan; Sepriano, Alexandre; da Silva, Jose A. P.; De Smet, Lukas; Sparks, Jeffrey A.; Steyerberg, Ewout W.; Studenic, Paul; Wethington, Elisabeth; Landewe, Robert L.; Raza, Karim; van der Helm-van Mil, Annette H. M.
Serum extracellular matrix biomarkers in rheumatoid arthritis, psoriatic arthritis and psoriasis and their association with hand function

类风湿关节炎、银屑病关节炎和银屑病患者血清细胞外基质生物标志物及其与手功能的关系

SCIENTIFIC REPORTS
IF3.9
2025-04-210
OA
Port, Helena; Coppers, Birte; Tragl, Sonja; Manger, Eva; Niemiec, Lisa M.; Bayat, Sara; Simon, David; Fagni, Filippo; Corte, Giulia; Bay-Jensen, Anne-Christine; Tascilar, Koray; Hueber, Axel J.; Schmidt, Katja G.; Schoenau, Verena; Sticherling, Michael; Heinrich, Simon; Leyendecker, Sigrid; Bohr, Daniela; Schett, Georg; Kleyer, Arnd; Holm Nielsen, Signe; Liphardt, Anna-Maria
Advancement and independent validation of a deep learning-based tool for automated scoring of nail psoriasis severity using the modified nail psoriasis severity index

基于改良型甲银屑病严重程度指数，对一种用于甲银屑病严重程度自动评分的深度学习工具进行改进与独立验证。

FRONTIERS IN MEDICINE
IF3
2025-04-020
OA
Kemenes, Stephan; Chang, Liu; Schlereth, Maja; de Sousa, Rita Noversa; Minopoulou, Ioanna; Fenzl, Pauline; Corte, Giulia; Mutlu, Melek Yalcin; Hoener, Michael Wolfgang; Sagonas, Ioannis; Coppers, Birte; Liphart, Anna-Maria; Simon, David; Kleyer, Arnd; Folle, Lukas; Sticherling, Michael; Schett, Georg; Maier, Andreas; Fagni, Filippo
Anti-CD19 CAR T cell therapy induces antibody seroconversion and complete B cell depletion in the bone marrow of a therapy- refractory patient with ANCA associated vasculitis-

抗CD19 CAR T细胞疗法诱导一例对疗法耐药的ANCA相关血管炎患者的骨髓中抗体血清转化及B细胞完全耗竭。

ANNALS OF THE RHEUMATIC DISEASES
IF20.6
2025-03-011
PRE
Minopoulou, Ioanna; Wilhelm, Artur; Albach, Fredrik; Kleyer, Arnd; Wiebe, Edgar; Schallenberg, Simon; Fleischmann, Anja; Frick, Mareike; Damm, Frederik; Gogolok, Julia; Serve, Sebastian; Locher, Benjamin Nick; Borie, Dominic; Casteleyn, Vincent; Biesen, Robert; Doerner, Thomas; Alexander, Tobias; Zernicke, Jan; Movassaghi, Kamran; Huetter-Kroenke, Marie Luise; Schrezenmeier, Eva; Schreiber, Adrian; Schneider, Udo; Bullinger, Lars; Kroenke, Gerhard; Penack, Olaf; Simon, David
Unveiling Metabolic Similarities of Entheses in Patients with Psoriasis and Psoriatic Arthritis Using Noninvasive In Vivo Molecular Imaging: Results From a Cross-sectional Exploratory Study

使用无创体内分子成像揭示银屑病和银屑病关节炎患者的代谢相似性: 横断面探索性研究的结果

ARTHRITIS & RHEUMATOLOGY
IF10.9
2024-07-081
OAAI
Fagni, Filippo; Tascilar, Koray; Noversa de Sousa, Rita; Bayat, Sara; Sollfrank, Lukas; Kleyer, Arnd; Sticherling, Michael; Regensburger, Adrian P.; Knieling, Ferdinand; Neurath, Markus F.; Schett, Georg; Waldner, Maximilian; Simon, David
ASSESSMENT OF S95011 (OSE-127, LUSVERTIKIMAB), AN ANTI-INTERLEUKIN 7 RECEPTOR MONOCLONAL ANTIBODY, IN PATIENTS WITH PRIMARY SJÖGREN'S SYNDROME: AN INTERNATIONAL MULTICENTRE, RANDOMIZED, DOUBLE-BLIND, PLACEBO- CONTROLLED, PHASE 2A STUDY

评估S95011（OSE-127，LUSVERTIKIMAB），一种抗白介素7受体单克隆抗体，在原发性舍格伦综合征患者中的研究：一项国际多中心、随机、双盲、安慰剂对照、2A期研究

ANNALS OF THE RHEUMATIC DISEASES
IF20.6
2024-06-010
PRE
Fisher, B.; Szanto, A.; Rischmueller, M.; Varga, T.; Kleyer, A.; Finzel, S.; Meijide, J. A. Garcia; Sanchez-Burson, J.; Galtier, S.; Sandre, C.; Mariette, X.
METABOLIC REWIRING PROMOTES ANTIINFLAMMATORY EFFECTS OF GLUCOCORTICOIDS

代谢重编程促进糖皮质激素的抗炎作用

ANNALS OF THE RHEUMATIC DISEASES
IF20.6
2024-06-010
PRE
Auger, J. P.; Zimmermann, M.; Faas, M.; Stifel, U.; Chambers, D.; Krishnacoumar, B.; Taudte, R. V.; Grund, C.; Scholtysek, C.; Uderhardt, S.; Mate, M. Pascual; Stoll, C.; Boettcher, M.; Palumbo-Zerr, K.; Mangan, M.; Dzamukova, M.; Kieler, M.; Hofmann, M.; Blueml, S.; Schabbauer, G.; Mougiakakos, D.; Sonnewald, U.; Hartmann, F.; Simon, D.; Kleyer, A.; Grueneboom, A.; Finotto, S.; Latz, E.; Hofmann, J.; Schett, G.; Tuckermann, J.; Kroenke, G.

研究方向

暂未获取到该数据
G
Georg Schett
H 指数:154论文数:1,725被引数:9.7万
D
David Simón
H 指数:48论文数:464被引数:1.1万
A
Axel J. Hueber
H 指数:50论文数:295被引数:9,236
J
Jürgen Rech
H 指数:54论文数:339被引数:1.1万
J
Judith Haschka
H 指数:23论文数:128被引数:2,017
M
Matthias Englbrecht
H 指数:44论文数:176被引数:5,416
G
Gerhard Krönke
H 指数:59论文数:260被引数:1.4万
K
Koray Taşçılar
H 指数:33论文数:160被引数:3,899
J
Johannes Knitza
H 指数:34论文数:294被引数:5,288
M
Michael Sticherling
H 指数:58论文数:471被引数:1.1万