logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
H

Heather Gray-Edwards

u mass chan medical school
H指数:25
被引数:2,191

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Long-term comparative analysis of AAV9-mediated gene replacement therapies for spinal muscular atrophy in mice

AAV9介导的脊髓性肌萎缩症基因替代疗法在 mice 中的长期比较分析

Nature Communications
IF15.7
2026-05-230
OAAI
Xiupeng Chen; Qing Xie; Sarah J. Nath; Mojiao Tang; Hong Ma; Yasemin Özgür Günes; Tapan Sharma; Hao Liu; Mengtian Cui; Ailing Du; Mengjia Lu; Sophia Y. Liu; Boonying Wassamon; Mengyao Xu; Joseph Yunxi Wu; Qin Su; Timothy P. Fitzgibbons; Jinghua Liu; Fang Wan; Veena Kumanan; Ran He; Yijie Ma; Jun Yang; Heather L. Gray-Edwards; Thomas L. Gallagher; Phillip W. L. Tai; Guangping Gao; Jun Xie
Five-year analysis of efficacy and safety ofa bidirectional AAV gene therapy in Tay-Sachs sheep

Tay-Sachs绵羊中双向AAV基因疗法的疗效与安全性五年分析

JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2025-12-010
OA
Taghian, Toloo; Gallagher, Jillian; Bertrand, Stephanie; Baker, William C.; Mercado, Kalajan Lopez; Benatti, Hector R.; Hall, Erin; Lopez, Yvette; McElroy, Abigail; McCarthy, John T.; Pulaparthi, Sanjana; Fernau, Deborah; Mather, Samuel; Esteves, Sophia; Diffie, Elise; Gross, Amanda; Lahey, Hannah G.; Jiang, Xuntian; Parsley, Elizabeth; Gately, Rachael; Prestigiacomo, Rachel; Johnson, Siauna; Taylor, Amanda; Bierfeldt, Lindsey; Tuominen, Susan; Koehler, Jennifer; Gao, Guangping; Xie, Jun; Su, Qin; King, Robert; Gounis, Matthew J.; Anagnostakou, Vania; Puri, Ajit; Batista, Ana Rita; Sena-Esteves, Miguel; Martin, Douglas R.; Gray-Edwards, Heather
Treatment of a severe vascular disease using a bespoke CRISPR–Cas9 base editor in mice

使用定制的CRISPR–Cas9碱基编辑器治疗小鼠中的严重血管疾病

Nature Biomedical Engineering
IF26.6
2025-09-110
PRE
Christiano R. R. Alves; Sabyasachi Das; Vijai Krishnan; Leillani L. Ha; Lauren R. Fox; Hannah E. Stutzman; Claire E. Shamber; Pazhanichamy Kalailingam; Siobhan McCarthy; Christian L. Lino Cardenas; Claire E. Fong; Takahiko Imai; Sunayana Mitra; Shuqi Yun; Rachael K. Wood; Friederike M. C. Benning; Kangsan Roh; Joseph Lawton; Nahye Kim; Rachel A. Silverstein; Joana Ferreira da Silva; Demitri de la Cruz; Rashmi Richa; Jun Xie; Heather L. Gray-Edwards; Rajeev Malhotra; David Y. Chung; Luke H. Chao; Shengdar Q. Tsai; Casey A. Maguire; Mark E. Lindsay; Benjamin P. Kleinstiver; Patricia L. Musolino
Cerebrospinal Fluid Flow Enhancement (CFE) Increases the Spatial Distribution of Methotrexate after Intracerebroventricular Administration in a Sheep Model

脑脊液流动增强（CFE）可增加鞘内脑室给药后甲氨蝶呤在绵羊模型中的空间分布。

Molecular Pharmaceutics
IF4.5
2025-06-100
PRE
Hector Ribeiro Benatti; Toloo Taghian; Olivia Mihalek; Sarah Nath; Jillian Gallagher; Abigail McElroy; Erin F. Hall; Rrita Daci; Nathan K. Yingling; William C. Baker; Susan Tuominen; Lindsey Bierfeldt; Xuntian Jiang; Heather L. Gray-Edwards; Rachael W. Sirianni
Natural history progression of MRI brain volumetrics in type II late-infantile and juvenile GM1 gangliosidosis patients (vol 144, 109025, 2025)

II型晚婴期和青少年型GM1神经节苷脂贮积症患者MRI脑容积测量的自然病史进展（卷 144，109025，2025）

MOLECULAR GENETICS AND METABOLISM
IF3.5
2025-05-010
PRE
Kolstad, Josephine; Zoppo, Christopher; Johnston, Jean M.; D'Souza, Precilla; Kuehn, Anna Luisa; Vardar, Zeynep; Peker, Ahmet; Hader, Asma; Celik, Hakki; Lewis, Connor J.; Lindsay, Clifford; Rentiya, Zubir S.; Lebel, Catherine; Vedantham, Srinivasan; Vachha, Behroze; Gray-Edwards, Heather L.; Acosta, Maria T.; Tifft, Cynthia J.; Shazeeb, Mohammed Salman
Natural history progression of MRI brain volumetrics in type II late-infantile and juvenile GM1 gangliosidosis patients
MOLECULAR GENETICS AND METABOLISM
IF3.5
2025-03-010
PRE
Kolstad, Josephine; Zoppo, Christopher; Johnston, Jean M.; D'Souza, Precilla; Kuhn, Anna Luisa; Vardar, Zeynep; Peker, Ahmet; Hader, Asma; Celik, Hakki; Lewis, Connor J.; Lindsay, Clifford; Rentiya, Zubir S.; Lebel, Catherine; Vedantham, Srinivasan; Vachha, Behroze; Gray-Edwards, Heather L.; Acosta, Maria T.; Tifft, Cynthia J.; Shazeeb, Mohammed Salman
A minimally invasive endovascular approach to the cerebellopontine angle cistern enables broad CNS biodistribution of scAAV9-CB-GFP

一种针对小脑脑桥角池的微创经血管途径，可实现scAAV9-CB-GFP在CNS中的广泛生物分布。

MOLECULAR THERAPY
IF12
2024-10-011
OAAI
Benatti, Hector Ribeiro; Anagnostakou, Vania; Taghian, Toloo; Hall, Erin F.; Nath, Sarah; Heilman, Carl B.; Beneduce, Brandon M.; Leporati, Anita; Raskett, Christopher; Epshtein, Mark; King, Robert; Gounis, Matthew J.; Malek, Adel M.; Gray-Edwards, Heather L.
Life-Limiting Peripheral Organ Dysfunction in Feline Sandhoff Disease Emerges after Effective CNS Gene Therapy
ANNALS OF NEUROLOGY
IF7.7
2023-08-163
OA
Johnson, Aime K.; McCurdy, Victoria J.; Gray-Edwards, Heather L.; Maguire, Anne S.; Cochran, J. Nicholas; Gross, Amanda L.; Skinner, Haleigh E.; Randle, Ashley N.; Shirley, Jamie L.; Brunson, Brandon L.; Bradbury, Allison M.; Leroy, Stanley G.; Hwang, Misako; Rockwell, Hannah E.; Cox, Nancy R.; Baker, Henry J.; Seyfried, Thomas N.; Sena-Esteves, Miguel; Martin, Douglas R.
From mouse to sheep: Generating a sheep model and developing a gene therapy for sialidosis
MOLECULAR GENETICS AND METABOLISM
IF3.5
2023-02-010
PRE
Gallagher, Jillian; Gallant, Judith; Xu, Ping; Gately, Rachael; Bertrand, Stephanie; McElroy, Abigail; Hall, Erin; Benatti, Hector; Prestigiacomo, Rachel; Luk, Kevin; Fremuth, Leigh E.; van de Vlekkert, Diantha; Hu, Huimin; Toro, Camilo; d'Azzo, Alessandra; Tifft, Cynthia J.; Wolfe, Scot; Rivera, Jaime; Sena-Esteves, Miguel; Gray-Edwards, Heather
AAV gene therapy for Tay-Sachs disease
NATURE MEDICINE
IF50
2022-02-1067
OA
Flotte, Terence R.; Cataltepe, Oguz; Puri, Ajit; Batista, Ana Rita; Moser, Richard; McKenna-Yasek, Diane; Douthwright, Catherine; Gernoux, Gwladys; Blackwood, Meghan; Mueller, Christian; Tai, Phillip W. L.; Jiang, Xuntian; Bateman, Scot; Spanakis, Spiro G.; Parzych, Julia; Keeler, Allison M.; Abayazeed, Aly; Rohatgi, Saurabh; Gibson, Laura; Finberg, Robert; Barton, Bruce A.; Vardar, Zeynep; Shazeeb, Mohammed Salman; Gounis, Matthew; Tifft, Cynthia J.; Eichler, Florian S.; Brown, Robert H., Jr.; Martin, Douglas R.; Gray-Edwards, Heather L.; Sena-Esteves, Miguel
Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide
NATURE MEDICINE
IF50
2021-12-2399
OA
Tran, Helene; Moazami, Michael P.; Yang, Huiya; McKenna-Yasek, Diane; Douthwright, Catherine L.; Pinto, Courtney; Metterville, Jake; Shin, Minwook; Sanil, Nitasha; Dooley, Craig; Puri, Ajit; Weiss, Alexandra; Wightman, Nicholas; Gray-Edwards, Heather; Marosfoi, Miklos; King, Robert M.; Kenderdine, Thomas; Fabris, Daniele; Bowser, Robert; Watts, Jonathan K.; Brown, Robert H., Jr.

研究方向

暂未获取到该数据
M
Miguel Sena‐Esteves
H 指数:55论文数:222被引数:9,611
D
Douglas R. Martin
H 指数:32论文数:107被引数:2,983
A
Aime K. Johnson
H 指数:17论文数:68被引数:1,066
A
Ashley N. Randle
H 指数:14论文数:34被引数:710
C
Cynthia J. Tifft
H 指数:54论文数:312被引数:1.1万
X
Xuntian Jiang
H 指数:36论文数:129被引数:4,671
A
Amanda L. Gross
H 指数:16论文数:43被引数:900
T
Toloo Taghian
H 指数:10论文数:37被引数:477
V
Victoria J. McCurdy
H 指数:11论文数:21被引数:529
B
Brandon L. Brunson
H 指数:15论文数:26被引数:705