Joseph Therriault

mcgill university

H指数:46

被引数:9,747

个人简介

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教育背景

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工作经历

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荣誉奖项

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Tau-PET correlates of mild behavioral impairment in preclinical and prodromal Alzheimer's disease: A head-to-head comparison of Flortaucipir and MK6240

帕金森行为障碍在临床前和前驱期阿尔茨海默病中的Tau-PET相关性：Flortaucipir与MK6240的头对头比较

Alzheimers & Dementia

IF11.1

2026-09-290

OAAI

Isabella Bizzi; Arthur C. Macedo; Lydia Trudel; Joseph Therriault; Nesrine Rahmouni; Firoza Z. Lussier; Cécile Tissot; Gleb Bezgin; Étienne Aumont; Tevy Chan; Seyyed Ali Hosseini; Delphine Oliva-Lopez; Marina Pereira Gonçalves; Guilherme Povala; Pamela C. L. Ferreira; Bruna Bellaver; Livia Amaral; Emma Ruppert; Marina Scop Medeiros; Rayan Mroué; Andréia Rocha; Kok Pin Ng; Eduardo R. Zimmer; Joseph Masdeu; Belen Pascual; Val J. Lowe; Hwamee Oh; David N. Soleimani-Meigooni; Juan Fortea; Zahinoor Ismail; Suzanne Baker; Tharick A Pascoal; Pedro Rosa-Neto; for the HEAD Study

A centiloid-scaled crossover of amyloid and tau influences on plasma p-Tau217 along the Alzheimer’s disease continuum

阿尔茨海默病连续谱中，以百分之一洛德为单位计的淀粉样蛋白和tau蛋白影响对血浆p-Tau217的交叉影响

Alzheimers Research & Therapy

IF7.6

2026-09-290

OAAI

Astrocyte reactivity identifies p-tau217-positive individuals at elevated risk of cognitive decline across the Alzheimer’s disease continuum

星形胶质细胞反应性识别阿尔茨海默病连续谱中p-tau217阳性个体认知下降的高风险

Molecular Neurodegeneration

IF17.5

2026-09-210

OAAI

Bruna Bellaver; Guilherme Povala; Pamela C. L. Ferreira; Douglas T. Leffa; Guilherme Bauer-Negrini; João Pedro Ferrari-Souza; Firoza Z. Lussier; Livia Amaral; Raphael L. Tuma; Alvaro de Oliveira Franco; Helmet T. Karim; Chang Hyung Hong; Hyun Woong Roh; Nesrine Rahmouni; Arthur Macedo; Joseph Therriault; Stijn Servaes; Jenna Stevenson; Lydia Trudel; Cecile Tissot; Andréa L. Benedet; Nicholas J. Ashton; Henrik Zetterberg; Oscar L. Lopez; Julia Koefler; Riddhi Patira; Thomas K. Karikari; Sid O’bryant; Eduardo R. Zimmer; Joseph Masdeu; Juan Fortea; Dana L. Tudorascu; David N. Soleimani-Meigooni; Val J. Lowe; Hwamee Oh; Belen Pascual; Brian A. Gordon; Sang Joon Son; Suzanne Baker; Pedro Rosa-Neto; Tharick A. Pascoal

Differential associations of tau extent and load with brain metabolic and cognitive dysfunction in Alzheimer's disease

阿尔茨海默病中tau蛋白分布范围和负荷与脑代谢及认知功能障碍的差异性关联

EBioMedicine

IF10.8

2026-08-010

PRE

Macedo, Arthur C.; Trudel, Lydia; Hosseini, Seyyed Ali; Bezgin, Gleb; Quispialaya-Socualaya, Kely; Therriault, Joseph; Rahmouni, Nesrine; Tissot, Cecile; Woo, Marcel S.; Limberger, Christian; Machado, Luiza S.; Souza, Debora G.; Oliva-Lopez, Delphine; Mitchell, Stuart; Chan, Tevy; Hall, Brandon; Aumont, Etienne; Servaes, Stijn; Goncalves, Marina Pereira; Bernardes Real, Ana Paula; Klostranec, Jesse; Vitali, Paolo; Provost, Karine; Pascoal, Tharick A.; Zimmer, Eduardo R.; Soucy, Jean-Paul; Rosa-Neto, Pedro

对淀粉样蛋白和tau病理学反应的炎症相关蛋白质组变化

Alzheimers & Dementia

IF11.1

2026-01-080

Comparison of brain-derived versus conventional pTau biomarkers in CSF and plasma for detecting Alzheimer’s disease

脑源性tau蛋白与常规pTau生物标志物在脑脊液和血浆中检测阿尔茨海默病的比较

Brain Communications

IF4.5

2026-01-010

OAAI

Microglia as a key player in Aβ‐related astrocyte reactivity

小胶质细胞作为Aβ相关星形胶质细胞反应性的关键参与者

Alzheimers & Dementia

IF11.1

2025-12-250

OAAI

João Pedro Ferrari‐Souza; Guilherme Povala; Nesrine Rahmouni; Bruna Bellaver; Pamela C.L. Ferreira; Douglas Teixeira Leffa; Firoza Z Lussier; Cristiano Aguzzoli; Wagner Scheeren Brum; Marco Antônio De Bastiani; Giovanna Carello‐Collar; Wyllians Vendramini Borelli; Joseph Therriault; Arthur C. Macedo; Stijn Servaes; Jenna Stevenson; Ilaria Pola; Serge Gauthier; Diogo O. Souza; Lucas Porcello Schilling; Mychael V. Lourenco; Gallen Triana‐Baltzer; Hartmuth C. Kolb; Andrea L. Benedet; Nicholas J. Ashton; Dana L Tudorascu; Henrik Zetterberg; Kaj Blennow; Tharick A Pascoal; Pedro Rosa‐Neto; Eduardo R. Zimmer

In vivo-measured Lewy body pathology is associated with neuropsychiatric symptoms across the Alzheimer’s disease continuum

体内测量的路易体病理与阿尔茨海默病连续谱系中的神经精神症状相关

Molecular Psychiatry

IF10.1

2025-12-140

PRE

APOE ε4 potentiates tau related reactive astrogliosis assessed by cerebrospinal fluid YKL40 in Alzheimer’s disease

APOE ε4 增强阿尔茨海默病中与tau蛋白相关的反应性星形胶质细胞增生，该增生通过脑脊液YKL40进行评估。

Communications Medicine

IF6.3

2025-11-200

Lydia Trudel; Joseph Therriault; Arthur C. Macedo; Marcel S. Woo; Nesrine Rahmouni; Étienne Aumont; Stijn Servaes; Seyyed Ali Hosseini; João Pedro Ferrari-Souza; Bruna Bellaver; Pamela L. Ferreira; Tevy Chan; Yi-Ting Wang; Jaime Fernandez-Arias; Yansheng Zheng; Brandon Hall; Jenna Stevenson; Robert Hopewell; Chris Hung-Hsin Hsiao; Maxime Montembeault; Jesse Klostranec; Yasser Iturria-Medina; Paolo Vitali; Thomas K. Karikari; Andrea L. Benedet; Nicholas J. Ashton; Eduardo Zimmer; Serge Gauthier; Tharick A. Pascoal; Henrik Zetterberg; Kaj Blennow; Pedro Rosa-Neto

Microglia modulate Aβ-dependent astrocyte reactivity in Alzheimer’s disease

小胶质细胞调节阿尔茨海默病中Aβ依赖性的星形胶质细胞反应性

Nature Neuroscience

IF20

2025-11-060

OAAI

João Pedro Ferrari-Souza; Guilherme Povala; Nesrine Rahmouni; Bruna Bellaver; Pamela C. L. Ferreira; Marco Antônio De Bastiani; Douglas T. Leffa; Firoza Z. Lussier; Cristiano S. Aguzzoli; Wagner S. Brum; Giovanna Carello-Collar; Wyllians V. Borelli; Joseph Therriault; Arthur C. Macedo; Stijn Servaes; Jenna Stevenson; Ilaria Pola; Serge Gauthier; Diogo O. Souza; Lucas Porcello Schilling; Mychael V. Lourenco; Gallen Triana-Baltzer; Hartmuth C. Kolb; Andréa L. Benedet; Nicholas J. Ashton; Dana L. Tudorascu; Henrik Zetterberg; Kaj Blennow; Sterling C. Johnson; Tharick A. Pascoal; Pedro Rosa-Neto; Eduardo R. Zimmer

Optimized atlas for early tau-PET staging via native space segmentations.

通过原始空间分割优化的tau-PET早期分期图谱。

Neurobiology of Aging

IF3.5

2025-11-060

PRE

Reference proteins to improve Core 1 and Core 2 Alzheimer’s disease CSF and plasma biomarkers

参考蛋白质以改善核心1型和核心2型阿尔茨海默病脑脊液和血浆生物标志物

Brain

IF11.7

2025-10-060

OAAI

Linda Karlsson; Shorena Janelidze; Nicolas R Barthélemy; Kanta Horie; Joseph Therriault; Lorenzo Gaetani; Giovanni Bellomo; Suzanne E Schindler; Jacob Vogel; Ida Arvidsson; Kalle Åström; Brian A Gordon; Cyrus A Raji; Tammie L S Benzinger; John C Morris; Johanna Nilsson; Ann Brinkmalm; Sebastian Palmqvist; Erik Stomrud; Gemma Salvadó; Alexa Pichet Binette; Massimiliano Di Filippo; Lucilla Parnetti; Pedro Rosa-Neto; Kaj Blennow; Randall J Bateman; Niklas Mattsson-Carlgren; Oskar Hansson

Connectivity as a universal predictor of tau progression in atypical Alzheimer's disease

连接性作为非典型阿尔茨海默病中tau进展的通用预测因子。

BRAIN

IF11.7

2025-10-012

PRE

de Bruin, Hannah; Groot, Colin; Barthel, Henryk; Bischof, Gerard N.; Blazhenets, Ganna; Boellaard, Ronald; Boon, Baayla D. C.; Brendel, Matthias; Cash, David M.; Coath, William; Day, Gregory S.; Dickerson, Bradford C.; Doering, Elena; Drzezga, Alexander; van Dyck, Christopher H.; van Eimeren, Thilo; van der Flier, Wiesje M.; Fredericks, Carolyn A.; Fryer, Tim D.; van de Giessen, Elsmarieke; Gordon, Brian A.; Graff-Radford, Jonathan; Grinberg, Lea T.; Hansson, Oskar; Hobbs, Diana A.; Hoenig, Merle C.; Hoglinger, Gunter; Irwin, David J.; Jones, P. Simon; Josephs, Keith A.; Katsumi, Yuta; La Joie, Renaud; Lee, Edward B.; Levin, Johannes; Malpetti, Maura; Mcginnis, Scott M.; Mecca, Adam P.; Mohanty, Rosaleena; Nasrallah, Ilya M.; O'Brien, John T.; O'Dell, Ryan S.; Palleis, Carla; Perneczky, Robert; Phillips, Jeffrey S.; Putcha, Deepti; Rabinovici, Gil D.; Rahmouni, Nesrine; Rosa-Neto, Pedro; Rowe, James B.; Rullmann, Michael; Sabri, Osama; Saur, Dorothee; Schildan, Andreas; Schott, Jonathan M.; Schroeter, Matthias L.; Seeley, William W.; Servaes, Stijn; Sintini, Irene; Smith, Ruben; Spina, Salvatore; Stevenson, Jenna; Stomrud, Erik; Strandberg, Olof; Therriault, Joseph; Tideman, Pontus; Touroutoglou, Alexandra; Trainer, Anne E.; Visser, Denise; Wekselman, Fattin; Weston, Philip S. J.; Whitwell, Jennifer L.; Wolk, David A.; Yong, Keir; Pijnenburg, Yolande A. L.; Franzmeier, Nicolai; Ossenkoppele, Rik

Amyloid beta and tau are associated with the dual effect of neuroinflammation on neurodegeneration

A Amyloid beta和tau与神经炎症对神经退行性病变的双效作用相关。Alzheimers. Dement. 21:e70746

ALZHEIMERS & DEMENTIA

IF11.1

2025-09-292

OAAI

Povala, Guilherme; Bellaver, Bruna; Bastiani, Marco Antonio De; Ferrari-Souza, Joao Pedro; Aguzzoli, Cristiano S.; Leffa, Douglas T.; Ferreira, Pamela C. L.; Lussier, Firoza Z.; Rocha, Andreia; Zalzale, Hussein; Soares, Carolina; Bauer-Negrini, Guilherme; Therriault, Joseph; Rahmouni, Nesrine; Stevenson, Jenna; Servaes, Stijn; Tissot, Cecile; Zatt, Bruno; Karikari, Thomas K.; Ikonomovic, Milos D.; Villemagne, Victor L.; Gauthier, Serge; Zimmer, Eduardo R.; Tudorascu, Dana L.; Benedet, Andrea L.; Rosa-Neto, Pedro; Pascoal, Tharick A.

Rates of clinical progression according to biological Alzheimer's disease stages

根据生物性阿尔茨海默病分期的临床进展速率

Alzheimer's & Dementia

IF11.1

2025-09-150

OAAI

Plasma tau biomarkers for biological staging of Alzheimer’s disease

血浆tau生物标志物在阿尔茨海默病生物学分期中的应用

Nature Aging

IF19.4

2025-08-220

OAAI