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Philipp Sievers

Ruprecht-Karls University Heidelberg
H指数:35
被引数:5,043

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Functional proteomic and phosphoproteomic profiling of routine FFPE CNS tumor tissue complements genomic and epigenomic characterization

常规FFPE CNS肿瘤组织的功能蛋白质组学和磷酸化蛋白质组学分析补充了基因组学和表观基因组学的表征

Acta Neuropathologica
IF9.3
2026-09-250
OAAI
Dennis Friedel; Rhaissa Ribeiro da Silva; Ivan Abdulrazak Ahmed; Beatriz Martins Wolff; Anna Neuerburg; Ramona Irsevic; Shiva Ahmadi; Ashok Kumar Jayavelu; Andreas E. Kulozik; Olaf Witt; Stefan M. Pfister; Sandro M. Krieg; Wolfgang Wick; Andreas von Deimling; David E. Reuss; Felix Sahm; Philipp Sievers
Neuronal precursor cell persistence in ganglioglioma is associated with extracellular matrix remodeling and immune cell infiltration

神经前体细胞在神经节胶质瘤中的持续存在与细胞外基质重塑和免疫细胞浸润相关

Neuro-Oncology Advances
IF4.1
2026-08-100
OA
Jan Kueckelhaus⁠; Lucas Hoffmann; Joëlle A Menstell; David Niklas Zimmer; Jasim Kada-Benotmane; Junyi Zhang; Juergen Beck; Oliver Schnell; Roman Sankowski; Philipp Sievers; Felix Sahm; Daniel Delev; Dieter Henrik Heiland⁠; null
Distinct molecular subgroups in pediatric and young-onset meningiomas require age-adapted risk stratification

儿童及年轻起病型脑膜瘤存在不同的分子亚群，需采用年龄适应性的风险分层策略

Nature Communications
IF15.7
2026-07-140
OAAI
Natalie Berghaus; Arnault Tauziède-Espariat; Thomas Hielscher; Dilan Savran; Daniel Schrimpf; Kirsten Göbel; Eric Stutheit-Zhao; Lukas Friedrich; Felix Keller; Fuat Kaan Aras; Filippo Nozzoli; Dominik Sturm; Christine L. White; Simone Schmid; Christian Mawrin; Julia E. Neumann; Till Acker; Rudi Beschorner; Christian Hartmann; Irem Saribiyik; Arda Inan; Ayça Erşen-Danyeli; Mariëtte E. G. Kranendonk; Sybren L. N. Maas; Eelke M. Bos; Eleonora Aronica; Saskia M. Peerdeman; Nikki B. Thuijs; Angelika Mühlebner; Benno Kusters; Wilfred F. A. den Dunnen; Cinzia E. Lavarino; Stéphanie Puget; Jason Chiang; Sonika Dahiya; Melike Pekmezci; Arie Perry; Oluwadamilola Akanji; Miriam Ratliff; Christel Herold-Mende; Sandro M. Krieg; Wolfgang Wick; Stefan M. Pfister; Pieter Wesseling; Andreas von Deimling; Pascale Varlet; Felix Sahm; Philipp Sievers
Hetairos is a histology-based artificial intelligence model for predicting central nervous system tumor methylation subtypes

Hetairos是一种基于组织学的人工智能模型，用于预测中枢神经系统肿瘤甲基化亚型

Nature Cancer
IF28.5
2026-06-100
OAAI
Darui Jin; Artem Shmatko; Areeba Patel; Samuel Rutz; Lukas Friedrich; Rouzbeh Banan; Ramin Rahmanzade; Philipp Sievers; Stefan Hamelmann; Daniel Schrimpf; Kirsten Göbel; Henri Bogumil; Sybren L. N. Maas; Martin Sill; Felix E. Hinz; Abigail K. Suwala; Felix Keller; Antje Habel; Gleb Rukhovich; Ferdinand Zettl; Obada T. Alhalabi; Sebastian Ille; Jannik Sehring; Daniel Amsel; Benedikt Wiestler; Pedro Piovesan Lago; Bogdana Suchorska; Olfat Ahmad; Dominik Sturm; David Reuss; Pieter Wesseling; Adelheid Wöhrer; Frank L. Heppner; Ingmar Blümcke; Claire Delbridge; Martin Jakobs; Christel Herold-Mende; Sandro M. Krieg; Wolfgang Wick; David T. W. Jones; Stefan M. Pfister; Maysa Al-Hussaini; Yanghao Hou; Felipe D’Almeida Costa; Leonille Schweizer; Luca Bertero; Till Acker; Arnault Tauziede-Espariat; Pascale Varlet; Doron Merkler; Kristof Egervari; Hildegard Dohmen; Pablo Zoroquiain; Roger Gejman; Sebastian Brandner; Xiangzhi Bai; Andreas von Deimling; Felix Sahm; Moritz Gerstung
Glioneuronal Tumour With Neurocytic Differentiation (GNTN): a Molecularly Defined Tumour Type Formerly Referred to as Extraventricular Neurocytoma

胶质神经元肿瘤伴神经细胞分化（GNTN）：一种分子界定的肿瘤类型，曾被称为脑室外神经细胞瘤

Neuropathology and Applied Neurobiology
IF3.4
2026-05-210
OAAI
Alice Métais; Myriam Edjlali; Farah Sassi; Guillaume Chotard; Emmanuelle Uro-Coste; Benoit Lhermitte; Romain Appay; Giuseppe Pinto; Christian Thomas; Luca Bertero; Miriam Ratliff; Sandro M. Krieg; Andreas von Deimling; Felix Sahm; Pascale Varlet; Philipp Sievers
A microenvironment-determined risk continuum refines subtyping in meningioma and reveals determinants of machine learning-based tumor classification

微环境确定的风险连续体可改善脑膜瘤的亚型，并揭示基于机器学习的肿瘤分类的决定因素

Nature Genetics
IF29
2026-02-090
OAAI
Sybren L. N. Maas; Yiheng Tang; Eric Stutheit-Zhao; Ramin Rahmanzade; Christina Blume; Thomas Hielscher; Ferdinand Zettl; Salvatore Benfatto; Domenico Calafato; Martin Sill; Jasim Kada Benotmane; Yahaya A. Yabo; Felix Behling; Abigail Suwala; Helin Kardo; Michael Ritter; Matthieu Peyre; Roman Sankowski; Konstantin Okonechnikov; Philipp Sievers; Areeba Patel; David Reuss; Mirco J. Friedrich; Damian Stichel; Daniel Schrimpf; Thierry P. P. Van den Bosch; Katja Beck; Hans-Georg Wirsching; Gerhard Jungwirth; C. Oliver Hanemann; Katrin Lamszus; Nima Etminan; Andreas Unterberg; Christian Mawrin; Marc Remke; Olivier Ayrault; Peter Lichter; Guido Reifenberger; Michael Platten; Tim Kacprowski; Markus List; Josch K. Pauling; Jan Baumbach; Till Milde; Rachel Grossmann; Zvi Ram; Miriam Ratliff; Jan-Philipp Mallm; Marian C. Neidert; Eelke M. Bos; Marco Prinz; Michael Weller; Till Acker; Felix J. Hartmann; Matthias Preusser; Ghazaleh Tabatabai; Christel Herold-Mende; Sandro M. Krieg; David T. W. Jones; Stefan M. Pfister; Wolfgang Wick; Michel Kalamarides; Andreas von Deimling; Dieter Henrik Heiland; Volker Hovestadt; Moritz Gerstung; Matthias Schlesner; Felix Sahm
Advancing CNS tumor diagnostics with expanded DNA methylation-based classification

通过扩展的基于DNA甲基化的分类来推进CNS肿瘤诊断

Cancer Cell
IF44.5
2025-12-040
OAAI
Martin Sill; Daniel Schrimpf; Areeba Patel; Dominik Sturm; Natalie Jäger; Philipp Sievers; Leonille Schweizer; Rouzbeh Banan; David Reuss; Abigail Suwala; Andrey Korshunov; Damian Stichel; Annika K. Wefers; Ann-Christin Hau; Henning Boldt; Patrick N. Harter; Zied Abdullaev; Jamal Benhamida; Daniel Teichmann; Arend Koch
Hetairos enables AI-based histopathological classification of CNS tumours

Hetairos 实现了基于 AI 的 CNS 肿瘤组织病理学分类

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Patel, Areeba; Jin, Darui; Shmatko, Artem; Rahmanzade, Ramin; Friederich, Lukas; Schrimpf, Daniel; Sievers, Philipp; Alhalabi, Obada; Rutz, Samuel; Suwala, Abigail; Sturm, Dominik; Wesseling, Pieter; Woehrer, Adelheid; Hou, Yanghao; Costa, Felipe D'almeida; Ille, Sebastian; Al-Hussaini, Maysa; Bertero, Luca; Schweizer, Leonille; Wiestler, Benedikt; Snuderl, Matija; Pfister, Stefan M.; Jones, David T. W.; Varlet, Pascale; Tauziede-Espariat, Arnault; Acker, Till; Brandner, Sebastian; Krieg, Sandro; Wick, Wolfgang; Bai, Xiangzhi; Von Deimling, Andreas; Gerstung, Moritz; Sahm, Felix
MACHINE LEARNING AND MULTI-OMIC ANALYSIS IDENTIFY A MICROENVIRONMENT-DRIVEN MENINGIOMA RISK CONTINUUM UNDERLYING MOLECULAR CLASSIFICATIONS

机器学习和多组学分析识别出一种由微环境驱动的、与分子分类相关的脑膜瘤风险连续体

NEURO-ONCOLOGY
IF13.4
2025-11-010
PRE
Maas, Sybren; Tang, Yiheng; Stutheit-Zhao, Eric; Rahmanzade, Ramin; Hielscher, Thomas; Zettl, Ferdinand; Benfatto, Salvatore; Calafato, Domenico; Sill, Martin; Benotmane, Jasim Kada; Yabo, Yahaya; Peyre, Matthieu; Sankowski, Roman; Okonechnikov, Konstantin; Sievers, Philip; Patel, Areeba; Reuss, David; Hanemann, Oliver; Lamszus, Katrin; Etminan, Nima; Unterberg, Andreas; Mawrin, Christian; Grossmann, Rachel; Ram, Zvi; Ratliff, Miriam; Neidert, Marian; Bos, Eelke; Prinz, Marco; Weller, Michael; Acker, Till; Hartmann, Felix; Preusser, Matthias; Tabatabai, Ghazaleh; Herold-Mende, Christel; Krieg, Sandro; Jones, David; Pfister, Stefan; Wick, Wolfgang; Kalamarides, Michel; Von Deimling, Andreas; Heiland, Dieter Henrik; Hovestadt, Volker; Gerstung, Moritz; Schlesner, Matthias; Sahm, Felix
Advancing CNS tumor diagnostics with expanded DNA methylation-based classification

Sill M, Schrimpf D, Patel A, Sturm D, Jäger N, Sievers P, et al. 推进中枢神经系统肿瘤诊断，扩展基于DNA甲基化的分类方法。medRxiv. (2025). doi: 10.1093/neuonc/noaf201.1012

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Sill, Martin; Schrimpf, Daniel; Patel, Areeba; Sturm, Dominik; Jager, Natalie; Sievers, Philipp; Wick, Wolfgang; von Deimling, Andreas; Capper, David; Pfister, Stefan M.; Jones, David T. W.; Sahm, Felix
Author Correction: A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas

作者更正：FGFR 突变和共突变的多样化景观表明儿童低级别胶质瘤中存在潜在的治疗策略

Nature Communications
IF15.7
2025-10-090
OA
April A. Apfelbaum; Eric Morin; Dominik Sturm; Georges Ayoub; Jeromy DiGiacomo; Sher Bahadur; Bhavyaa Chandarana; Phoebe C. Power; Margaret M. Cusick; Dana Novikov; Prem Prabhakar; Robert E. Jones; Jayne Vogelzang; Connor C. Bossi; Seth Malinowski; Lewis M. Woodward; Tania A. Jones; John Jeang; Sarah W. Lamson; Jared Collins; Kelly Y. Cai; Jacquelyn S. Jones; Sehee Oh; Hyesung Jeon; Jinhua Wang; Amy Cameron; Patrick Rechter; Angela De Leon; Karthikeyan Murugesan; Meagan Montesion; Lee A. Albacker; Shakti H. Ramkissoon; Cornelis M. van Tilburg; Emily C. Hardin; Philipp Sievers; Felix Sahm; Kee Kiat Yeo; Tom Rosenberg; Susan N. Chi; Karen D. Wright; Steven Hébert; Sydney Peck; Alberto Picca; Valérie Larouche; Samuele Renzi; Sara J. Buhrlage; Tejus A. Bale; Amy A. Smith; Mehdi Touat; Nada Jabado; Eric S. Fischer; Michael J. Eck; Lissa Baird; Olaf Witt; Claudia L. Kleinman; Quang-De Nguyen; Denise Sheer; Sanda Alexandrescu; David T. W. Jones; Keith L. Ligon; Pratiti Bandopadhayay
Tumor-associated macrophages in meningiomas: a novel biomarker for poor survival outperforming the benefits of T cells

脑膜瘤中的肿瘤相关巨噬细胞：一种优于T细胞获益的新型不良生存预后生物标志物

Acta Neuropathologica
IF9.3
2025-10-090
OA
Catharina Lotsch; Rolf Warta; Fang Liu; Gerhard Jungwirth; Carmen Rommel; Mandy Barthel; Katrin Lamszus; Almuth F. Kessler; Niels Grabe; Mario Loehr; Ralf Ketter; Christian Senft; Sybren L. N. Maas; Philipp Sievers; Manfred Westphal; Sandro M. Krieg; Andreas Unterberg; Matthias Simon; Andreas von Deimling; Felix Sahm; David R. Raleigh; Christel Herold-Mende
A INTEGRATIVE MULTIOMICS ANALYSIS IDENTIFIES TUMOR-ASSOCIATED MACROPHAGES AS NOVEL INDEPENDENT BIOMARKER FOR POOR SURVIVAL IN MENINGIOMAS

整合多组学分析确定了肿瘤相关巨噬细胞作为脑膜瘤不良预后的新型独立生物标志物

NEURO-ONCOLOGY
IF13.4
2025-10-010
OAAI
Lotsch, C.; Warta, R.; Liu, F.; Jungwirth, G.; Rommel, C.; Lamszus, K.; Kessler, A.; Lohr, M.; Ketter, R.; Senft, C.; Maas, N.; Sievers, P.; Westphal, M.; Krieg, S. M.; Unterberg, A.; Simon, M.; von Deimling, A.; Sahm, F.; Raleigh, D.; Herold-Mende, C. C.
AI-BASED HISTOPATHOLOGICAL CLASSIFICATION OF CENTRAL NERVOUS SYSTEM TUMOURS

基于人工智能的中央神经系统肿瘤组织病理学分类

NEURO-ONCOLOGY
IF13.4
2025-10-010
OAAI
Jin, D.; Shmatko, A.; Patel, A.; Rahmanzade, R.; Friedrich, L.; Schrimpf, D.; Sievers, P.; Alhalabi, O.; Rutz, S. P.; Suwala, A. K.; Sturm, D.; Wesseling, P.; Woehrer, A.; Hou, Y.; D'almeida Costa, F.; Ille, S.; Al-Hussaini, M.; Bertero, L.; Schweizer, L.; Wiestler, B.; Snuderl, M.; Pfister, S. M.; Jones, D. T. W.; Varlet, P.; Tauziede-Espariat, A.; Acker, T.; Brandner, S.; Krieg, S. M.; Wick, W.; Bai, X.; von Deimling, A.; Gerstung, M.; Sahm, F.
Expansion of the spectrum of tumors diagnosed as myxopapillary ependymomas

对被诊断为粘液乳头型室管膜瘤的肿瘤谱系进行扩展

Acta Neuropathologica
IF9.3
2025-09-300
OA
Fuat Kaan Aras; Dennis Friedel; Felix Keller; Ferdinand Zettl; Rouzbeh Banan; Philipp Sievers; Abigail K. Suwala; Felix Hinz; Lukas Friedrich; Ivan Abdulrazak; Mozhgan Esmaeilibenvidi; Nima Etminan; Christel Herold-Mende; Wolfgang Wick; Sandro Krieg; Stefan M. Pfister; Andrey Korshunov; Isabell Bludau; Felix Sahm; David E. Reuss; Gianluca Sigismondo; Andreas von Deimling
A spatial map of MAPK-activated immunosuppressive myeloid populations in pediatric low-grade glioma

MAPK激活的免疫抑制性髓系细胞群在儿童低级别胶质瘤中的空间分布图

Nature Immunology
IF27.6
2025-09-150
PRE
Augusto Faria Andrade; Romain Sigaud; Evan Puligandla; Bridget Liu; Elham Karimi; Alva Annett; Morteza Rezanejad; Wajih Jawhar; Robert Taylor; Yi Cao; Simone Schmid; Florian Selt; Pablo Hernáiz Driever; Svea Horn; Philipp Sievers; Marco Prinz; Markus Glatzel; Christian Mawrin; Christian Hartmann; Camelia-Maria Monoranu; Liza Konnikova; Felix Sahm; Stefan M. Pfister; Olaf Witt; David T. W. Jones; Arend Koch; Claudia L. Kleinman; David Capper; Logan Walsh; Nada Jabado; Till Milde
PLAG1 fusions define a third subtype of CNS embryonal tumor with PLAG family gene alteration

PLAG1融合定义了具有PLAG家族基因改变的中枢神经系统胚胎性肿瘤的第三种亚型

Acta Neuropathologica
IF9.3
2025-08-020
OAAI
Michaela-Kristina Keck; Maysa Al-Hussaini; Nisreen Amayiri; Akosua Adoma Boakye Yiadom; Gabriel Chamyan; Edmund Cheesman; Cécile Faure-Conter; Miguel Garcia-Ariza; Guillaume Gauchotte; Martin Hasselblatt; Mette Jorgensen; John-Paul Kilday; Gabriela Lamas; Cinzia Lavarino; Marilyn M. Li; Fabiana Lubieniecki; Ossama M. Maher; David Meyronet; Jan Mueller; Mariarita Santi; Ulrich Schüller; Ana Luiza Seidinger; Martin Sill; Sniya Sudhakar; María Tallón García; Arnault Tauziede-Espariat; Pascale Varlet; Alexandre Vasiljevic; Andrea Wittmann; Andreas von Deimling; David A. Solomon; Felix Sahm; Anna Tietze; Katja von Hoff; Philipp Sievers; David T. W. Jones

研究方向

暂未获取到该数据
F
Felix Sahm
H 指数:93论文数:1,069被引数:4.0万
A
Andreas von Deimling
H 指数:175论文数:1,793被引数:17.3万
S
Stefan M. Pfister
H 指数:159论文数:2,105被引数:12.8万
D
David Jones
H 指数:144论文数:1,486被引数:10.4万
D
Daniel Schrimpf
H 指数:52论文数:293被引数:1.4万
W
Wolfgang Wick
H 指数:142论文数:1,641被引数:9.5万
A
Andrey Korshunov
H 指数:127论文数:831被引数:7.3万
D
Damian Stichel
H 指数:47论文数:196被引数:1.0万
C
Christel Herold‐Mende
H 指数:110论文数:992被引数:7.9万
M
Martin Sill
H 指数:58论文数:336被引数:1.8万