Jack F. Shern - Publications, H-index & Citations

Jack F. Shern

hopital universitaire saint-louis - aphp

41H指数

512论文数

9.6K被引数

收录论文 71

发表时间

FANCM is required for the PAX3::FOXO1-driven oncogenic program in rhabdomyosarcoma FANCM在横纹肌肉瘤中对于PAX3::FOXO1驱动的癌基因程序是必需的

Cell Reports

IF6.9

2026-09-01

PREAI

Delaney, Christopher D.; Lu, Min; Zimmerman, Seth P.; Meng, Yingying; Vaganay, Camille; Cerda-Smith, Christian G.; Liu, Annie; Hoj, Jacob P.; Killarney, Shane T.; Dillon, Kerry; Stewart, Amy E.; Huang, Kevin; Caci, Julia D.; White, Olivia; Puissant, Alexandre; Root, David E.; Shern, Jack F.; Eyler, Christine E.; Chen, Chun-Wei David; Counter, Christopher M.; Linardic, Corinne M.; Zou, Lee; Wood, Kris C.

Fusion-positive rhabdomyosarcoma oncofusions share a common interactome 融合阳性横纹肌肉瘤癌融合蛋白共享共同的相互作用组

Nature Communications

IF15.7

2026-05-28

OAAI

S. P. Zimmerman; C. D. Delaney; B. K. Lau; L. B. DeGraw; G. H. Rupprecht; M. J. A. Groot Koerkamp; T. de Souza; J. Drost; R. A. Schoot; M. T. Meister; J. F. Shern; L. M. Wagner; G. G. Wang; K. C. Wood; C. M. Linardic; C. M. Counter

The prostate is a common site of disease in patients with MEN2B and medullary thyroid carcinoma MEN2B和髓样甲状腺癌患者中前列腺是常见的疾病部位

Endocrine-Related Cancer

IF4.6

2026-01-01

PREAI

Kraft, Ira L.; Akshintala, Srivandana; Gross, Andrea; Dombi, Eva; Turkbey, Baris; Bednarova, Sandra; Ward, John F.; Yedururi, Sireesha; Merino, Maria; Pinto, Peter A.; Widemann, Brigitte C.; Shern, Jack F.; Waguespack, Steven G.; Glod, John

Daytime SHP2 inhibitor dosing, when immune cell numbers are elevated, shrinks neurofibromas 日间给予SHP2抑制剂（在免疫细胞数量升高时）可缩小神经纤维瘤

LIFE SCIENCE ALLIANCE

IF2.9

2025-09-24

PREAI

Ahmari, Niousha; Choi, Kwangmin; Wu, Jianqiang; Rizvi, Tilat A.; Jackson, Mark; Kershner, Leah J.; Kim, Mi-Ok; Zhang, Xiyuan; Dombi, Eva; Shern, Jack; Hildeman, David A.; Ratner, Nancy

Prioritization of novel agents for further investigation in pediatric non-rhabdomyosarcoma soft tissue sarcomas: A report from the Children’s Oncology Group 新型药物在儿童非横纹肌肉瘤软组织肉瘤中的优先级排序及进一步研究的报告：来自儿童肿瘤组的报告

European Journal of Cancer

IF7.1

2025-07-06

PREAI

Jacquelyn N. Crane; David P. Douglass; Sapna Oberoi; Natalie B. Collins; Ajay Gupta; Jonathan L. Metts; Viswatej Avutu; Filemon S. Dela Cruz; Jessica L. Davis; Noah C. Federman; Susan M. Hiniker; Theodore W. Laetsch; Corinne M. Linardic; Fariba Navid; Raya Saab; David S. Shulman; Jack F. Shern; Alice Soragni; Elizabeth A. Stewart; Stephanie Terezakis; Brenda J. Weigel; Aaron R. Weiss

The impact of genetic ancestry on survival outcomes in pediatric rhabdomyosarcoma: A report from the Children’s Oncology Group 遗传祖先对儿童横纹肌肉瘤生存结局的影响：美国儿童肿瘤学会报告

Human Genetics and Genomics Advances

IF3.6

2025-06-09

OAAI

Ekene A. Onwuka; Christina L. Magyar; Bailey A. Martin-Giacalone; Michael E. Scheurer; Deborah A. Marquez-Do; Mark Zobeck; Elizabeth G. Atkinson; Erin R. Rudzinski; Michael A. Arnold; Donald A. Barkauskas; David Hall; Javed Khan; Jack F. Shern; Paul Scheet; Brian Crompton; Corinne M. Linardic; Douglas S. Hawkins; Rajkumar Venkatramani; Lisa Mirabello; Chad D. Huff; Philip J. Lupo

MYCN and KAT2A form a feedforward loop to drive an oncogenic transcriptional program in neuroblastoma MYCN和KAT2A形成一个前馈回路，驱动神经母细胞瘤中的癌基因转录程序。

ONCOGENESIS

IF6.4

2025-04-24

OAAI

Zhihui Liu; Jason J. Hong; Xiyuan Zhang; Carly M. Sayers; Wendy Fang; Man Xu; Sydney Loria; Sakereh Maskal; Haiyan Lei; Haitao Wu; Rolf Swenson; Jordan L. Meier; Jack F. Shern; Carol J. Thiele

ASAP1 and ARF1 Regulate Myogenic Differentiation in Rhabdomyosarcoma by Modulating TAZ Activity

MOLECULAR CANCER RESEARCH

IF4.7

2024-11-04

OAAI

Hebron, Katie E.; Perkins, Olivia L.; Kim, Angela; Jian, Xiaoying; Girald-Berlingeri, Sofia A.; Lei, Haiyan; Shern, Jack F.; Conner, Elizabeth A.; Randazzo, Paul A.; Yohe, Marielle E.

Targeting SWI/SNF ATPases reduces neuroblastoma cell plasticity 靶向SWI/SNF atp酶降低神经母细胞瘤细胞可塑性

EMBO JOURNAL

IF8.3

2024-08-22

PREAI

Xu, Man; Hong, Jason J.; Zhang, Xiyuan; Sun, Ming; Liu, Xingyu; Kang, Jeeyoun; Stack, Hannah; Fang, Wendy; Lei, Haiyan; Lacoste, Xavier; Okada, Reona; Jung, Raina; Nguyen, Rosa; Shern, Jack F.; Thiele, Carol J.; Liu, Zhihui

ATR inhibitors synergize with DHFR inhibitors in rhabdomyosarcoma cells by disrupting DNA damage checkpoint

CANCER RESEARCH

IF16.6

2024-04-05

PREAI

Jo, Ukhyun; Annor, George K.; Shern, Jack F.

Targeting CDK8: A translatable therapeutic approach for fusion-positive aRMS

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Zhang, Susu; Malone, Clare; Guedes, Brian; Engel, Kathleen; Just, Marissa; Ross, Kenneth; Fahs, Assil; Digiovanni, Giulia; Granum, Diyana; Bentley, Rex; Barbar, Leen; Cerda-Smith, Christian; Mendes, Elizabeth; Erdogan, Ozgun; Kovach, Alexander; Oristian, Kristianne; Zimmerman, Seth; Shern, Jack F.; Wood, Kris; Counter, Chris; Linardic, Corinne M.; Stegmaier, Kimberly

KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma

NATURE COMMUNICATIONS

IF15.7

2024-02-24

OAAI

Kim, Yong Yean; Gryder, Berkley E.; Sinniah, Ranuka; Peach, Megan L.; Shern, Jack F.; Abdelmaksoud, Abdalla; Pomella, Silvia; Woldemichael, Girma M.; Stanton, Benjamin Z.; Milewski, David; Barchi Jr, Joseph J.; Schneekloth Jr, John S.; Chari, Raj; Kowalczyk, Joshua T.; Shenoy, Shilpa R.; Evans, Jason R.; Song, Young K.; Wang, Chaoyu; Wen, Xinyu; Chou, Hsien-Chao; Gangalapudi, Vineela; Esposito, Dominic; Jones, Jane; Procter, Lauren; O'Neill, Maura; Jenkins, Lisa M.; Tarasova, Nadya I.; Wei, Jun S.; McMahon, James B.; O'Keefe, Barry R.; Hawley, Robert G.; Khan, Javed

Estimated Prevalence, Tumor Spectrum, and Neurofibromatosis Type 1-Like Phenotype of CDKN2A-Related Melanoma-Astrocytoma Syndrome

JAMA DERMATOLOGY

IF11

2023-10-01

OAAI

Sargen, Michael R.; Kim, Jung; Potjer, Thomas P.; Velthuizen, Mary E.; Martir-Negron, Arelis E.; Odia, Yazmin; Helgadottir, Hildur; Hatton, Jessica N.; Haley, Jeremy S.; Thone, Gretchen; Widemann, Brigitte C.; Gross, Andrea M.; Yohe, Marielle E.; Kaplan, Rosandra N.; Shern, Jack F.; Sundby, R. Taylor; Astiazaran-Symonds, Esteban; Yang, Xiaohong R.; Carey, David J.; Tucker, Margaret A.; Stewart, Douglas R.; Goldstein, Alisa M.

Urine cell-free DNA multi-omics to detect molecular residual disease and predict survival in bladder cancer patients

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Chauhan, Pradeep Singh; Shiang, Alexander L.; Alahi, Irfan; Sundby, R. Taylor; Feng, Wenjia; Gungoren, Bilge; Nawaf, Cayce; Chen, Kevin; Babbra, Ramandeep K.; Harris, Peter K.; Qaium, Faridi; Hatscher, Casey; Antiporda, Anna; Brunt, Lindsey; Mayer, Lindsey R.; Shern, Jack F.; Baumann, Brian C.; Kim, Eric H.; Reimers, Melissa A.; Smith, Zachary L.; Chaudhuri, Aadel A.

SWI/SNF-associated DPF1 is a unique transcriptional regulator of malignant peripheral nerve sheath tumors

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Murray, Bega; Zhang, Xiyuan; Abbas, Shahroze; Lei, Haiyan; Jafarah, Hilda; Shern, Jack F.

SNAI2 enhances oncogenesis in malignant peripheral nerve sheath tumors

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Jafarah, Hilda; Murray, Bega; Shern, Jack; Zhang, Xiyuan

Cell-free DNA fragmentomics distinguish between benign, pre-malignant and malignant peripheral nerve sheath tumors in neurofibromatosis type 1

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Pan, Alex C.; Sundby, Russell Taylor; Szymanski, Jeffrey J.; Jones, Paul A.; Harris, Peter K.; Chaudhuri, Aadel A.; Hirbe, Angela C.; Shern, Jack F.

Urine cell-free DNA multi-omics to detect MRD and predict survival in bladder cancer patients

NPJ PRECISION ONCOLOGY

IF8

2023-01-19

OAAI

Chauhan, Pradeep S.; Shiang, Alexander; Alahi, Irfan; Sundby, R. Taylor; Feng, Wenjia; Gungoren, Bilge; Nawaf, Cayce; Chen, Kevin; Babbra, Ramandeep K.; Harris, Peter K.; Qaium, Faridi; Hatscher, Casey; Antiporda, Anna; Brunt, Lindsey; Mayer, Lindsey R.; Shern, Jack F.; Baumann, Brian C.; Kim, Eric H.; Reimers, Melissa A.; Smith, Zachary L.; Chaudhuri, Aadel A.

HAND2 Assists MYCN Enhancer Invasion to Regulate a Noradrenergic Neuroblastoma Phenotype

CANCER RESEARCH

IF16.6

2023-01-04

OAAI

Xu, Man; Sun, Ming; Zhang, Xiyuan; Nguyen, Rosa; Lei, Haiyan; Shern, Jack F.; Thiele, Carol J.; Liu, Zhihui

Loss of CASZ1 tumor suppressor linked to oncogenic subversion of neuroblastoma core regulatory circuitry

CELL DEATH & DISEASE

IF9.6

2022-10-15

OAAI

Liu, Zhihui; Zhang, Xiyuan; Xu, Man; Lei, Haiyan; Shern, Jack F.; Thiele, Carol J.

研究方向