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Loss of the DNA Repair Gene RNase H2 Identifies a Unique Subset of DDR-Deficient Leiomyosarcomas Nakazawa, Michael S.; Silverman, Ian M.; Rimkunas, Victoria; Veloso, Artur; Glodzik, Dominik; Johnson, Adrienne; Ohsumi, Toshiro K.; Patel, Shreyaskumar R.; Conley, Anthony P.; Roland, Christina L.; Soliman, Pamela T.; Beird, Hannah C.; Wu, Chia-Chin; Ingram, Davis R.; Lazcano, Rossana; Song, Dawon; Wani, Khalida M.; Lazar, Alexander J.; Yap, Timothy A.; Wang, Wei-Lien; Livingston, J. Andrew 分享 收藏
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Subclonal Somatic Copy-Number Alterations Emerge and Dominate in Recurrent Osteosarcoma Kinnaman, Michael D.; Zaccaria, Simone; Makohon-Moore, Alvin; Arnold, Brian; Levine, Max F.; Gundem, Gunes; Arango Ossa, Juan E.; Glodzik, Dominik; Rodriguez-Sanchez, M. Irene; Bouvier, Nancy; Li, Shanita; Stockfisch, Emily; Dunigan, Marisa; Cobbs, Cassidy; Bhanot, Umesh K.; You, Daoqi; Mullen, Katelyn; Melchor, Jerry P.; Ortiz, Michael V.; O'Donohue, Tara J.; Slotkin, Emily K.; Wexler, Leonard H.; Dela Cruz, Filemon S.; Hameed, Meera R.; Glade Bender, Julia L.; Tap, William D.; Meyers, Paul A.; Papaemmanuil, Elli; Kung, Andrew L.; Iacobuzio-Donahue, Christine A. 分享 收藏
Detection of Biallelic Loss of DNA Repair Genes in Formalin-Fixed, Paraffin-Embedded Tumor Samples Using a Novel Tumor-Only Sequencing Panel Glodzik, Dominik; Selenica, Pier; Rogge, Ryan A.; Silverman, Ian M.; Mandelker, Diana; Harris, Sam; Zhao, Jianhua; Zinda, Michael; Veloso, Artur; Malani, Nirav; Riaz, Nadeem; Koehler, Maria; Daber, Robert D.; Johnson, Verity; Rimkunas, Victoria; Reis-Filho, Jorge S. 分享 收藏
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Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers Shukla, N.; Levine, M. F.; Gundem, G.; Domenico, D.; Spitzer, B.; Bouvier, N.; Arango-Ossa, J. E.; Glodzik, D.; Medina-Martinez, J. S.; Bhanot, U.; Gutierrez-Abril, J.; Zhou, Y.; Fiala, E.; Stockfisch, E.; Li, S.; Rodriguez-Sanchez, M., I; O'Donohue, T.; Cobbs, C.; Roehrl, M. H. A.; Benhamida, J.; Cardenas, F. Iglesias; Ortiz, M.; Kinnaman, M.; Roberts, S.; Ladanyi, M.; Modak, S.; Farouk-Sait, S.; Slotkin, E.; Karajannis, M. A.; Dela Cruz, F.; Bender, J. Glade; Zehir, A.; Viale, A.; Walsh, M. F.; Kung, A. L.; Papaemmanuil, E. 分享 收藏
Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR x LGR5 bispecific antibody with efficacy in epithelial tumors Herpers, Bram; Eppink, Berina; James, Mark, I; Cortina, Carme; Canellas-Socias, Adria; Boj, Sylvia F.; Hernando-Momblona, Xavier; Glodzik, Dominik; Roovers, Rob C.; van de Wetering, Marc; Bartelink-Clements, Carina; Zondag-van der Zande, Vanessa; Mateos, Jara Garcia; Yan, Kuan; Salinaro, Lucia; Basmeleh, Abdul; Fatrai, Szabolcs; Maussang, David; van Bueren, Jeroen J. Lammerts; Chicote, Irene; Serna, Garazi; Cabellos, Laia; Ramirez, Lorena; Nuciforo, Paolo; Salazar, Ramon; Santos, Cristina; Villanueva, Alberto; Attolini, Camille Stephan-Otto; Sancho, Elena; Palmer, Hector G.; Tabernero, Josep; Stratton, Michael R.; de Kruif, John; Logtenberg, Ton; Clevers, Hans; Price, Leo S.; Vries, Robert G. J.; Batlle, Eduard; Throsby, Mark 分享 收藏
Revealing the Impact of Structural Variants in Multiple Myeloma 揭示结构变异对多发性骨髓瘤的影响 Rustad, Even H.; Yellapantula, Venkata D.; Glodzik, Dominik; Maclachlan, Kylee H.; Diamond, Benjamin; Boyle, Eileen M.; Ashby, Cody; Blaney, Patrick; Gundem, Gunes; Hultcrantz, Malin; Leongamornlert, Daniel; Angelopoulos, Nicos; Agnelli, Luca; Auclair, Daniel; Zhang, Yanming; Dogan, Ahmet; Bolli, Niccolo; Papaemmanuil, Elli; Anderson, Kenneth C.; Moreau, Philippe; Avet-Loiseau, Herve; Munshi, Nikhil C.; Keats, Jonathan J.; Campbell, Peter J.; Morgan, Gareth J.; Landgren, Ola; Maura, Francesco 分享 收藏
Cancer therapy shapes the fitness landscape of clonal hematopoiesis 癌症治疗塑造了克隆造血的健康景观 Bolton, Kelly L.; Ptashkin, Ryan N.; Gao, Teng; Braunstein, Lior; Devlin, Sean M.; Kelly, Daniel; Patel, Minal; Berthon, Antonin; Syed, Aijazuddin; Yabe, Mariko; Coombs, Catherine C.; Caltabellotta, Nicole M.; Walsh, Mike; Offit, Kenneth; Stadler, Zsofia; Mandelker, Diana; Schulman, Jessica; Patel, Akshar; Philip, John; Bernard, Elsa; Gundem, Gunes; Ossa, Juan E. Arango; Levine, Max; Martinez, Juan S. Medina; Farnoud, Noushin; Glodzik, Dominik; Li, Sonya; Robson, Mark E.; Lee, Choonsik; Pharoah, Paul D. P.; Stopsack, Konrad H.; Spitzer, Barbara; Mantha, Simon; Fagin, James; Boucai, Laura; Gibson, Christopher J.; Ebert, Benjamin L.; Young, Andrew L.; Druley, Todd; Takahashi, Koichi; Gillis, Nancy; Ball, Markus; Padron, Eric; Hyman, David M.; Baselga, Jose; Norton, Larry; Gardos, Stuart; Klimek, Virginia M.; Scher, Howard; Bajorin, Dean; Paraiso, Eder; Benayed, Ryma; Arcila, Maria E.; Ladanyi, Marc; Solit, David B.; Berger, Michael F.; Tallman, Martin; Garcia-Closas, Montserrat; Chatterjee, Nilanjan; Diaz, Luis A., Jr.; Levine, Ross L.; Morton, Lindsay M.; Zehir, Ahmet; Papaemmanuil, Elli 分享 收藏
Comprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers Glodzik, Dominik; Bosch, Ana; Hartman, Johan; Aine, Mattias; Vallon-Christersson, Johan; Reutersward, Christel; Karlsson, Anna; Mitra, Shamik; Nimeus, Emma; Holm, Karolina; Hakkinen, Jari; Hegardt, Cecilia; Saal, Lao H.; Larsson, Christer; Malmberg, Martin; Ryden, Lisa; Ehinger, Anna; Loman, Niklas; Kvist, Anders; Ehrencrona, Hans; Nik-Zainal, Serena; Borg, Ake; Staaf, Johan 分享 收藏
A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies (vol 1, pg 249, 2020) Degasperi, Andrea; Amarante, Tauanne Dias; Czarnecki, Jan; Shooter, Scott; Zou, Xueqing; Glodzik, Dominik; Morganella, Sandro; Nanda, Arjun S.; Badja, Cherif; Koh, Gene; Momen, Sophie E.; Georgakopoulos-Soares, Ilias; Dias, Joao M. L.; Young, Jamie; Memari, Yasin; Davies, Helen; Nik-Zainal, Serena 分享 收藏
11p15.5 epimutations in children with Wilms tumor and hepatoblastoma detected in peripheral blood Fiala, Elise M.; Ortiz, Michael V.; Kennedy, Jennifer A.; Glodzik, Dominik; Fleischut, Megan Harlan; Duffy, Kelly A.; Hathaway, Evan R.; Heaton, Todd; Gerstle, Justin T.; Steinherz, Peter; Shukla, Neerav; McNeer, Nicole; Tkachuk, Kaitlyn; Bouvier, Nancy; Cadoo, Karen; Carlo, Maria I.; Latham, Alicia; Gault, Marianne Dubard; Joseph, Vijai; Kemel, Yelena; Kentsis, Alex; Stadler, Zsofia; La Quaglia, Michael; Papaemmanuil, Elli; Friedman, Danielle; Ganguly, Arupa; Kung, Andrew; Offit, Kenneth; Kalish, Jennifer M.; Walsh, Michael F. 分享 收藏
A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies Degasperi, Andrea; Amarante, Tauanne Dias; Czarnecki, Jan; Shooter, Scott; Zou, Xueqing; Glodzik, Dominik; Morganella, Sandro; Nanda, Arjun S.; Badja, Cherif; Koh, Gene; Momen, Sophie E.; Georgakopoulos-Soares, Ilias; Dias, Joao M. L.; Young, Jamie; Memari, Yasin; Davies, Helen; Nik-Zainal, Serena 分享 收藏
Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study 基于人群的临床研究中三阴性乳腺癌的全基因组测序 Staaf, Johan; Glodzik, Dominik; Bosch, Ana; Vallon-Christersson, Johan; Reutersward, Christel; Hakkinen, Jari; Degasperi, Andrea; Amarante, Tauanne Dias; Saal, Lao H.; Hegardt, Cecilia; Stobart, Hilary; Ehinger, Anna; Larsson, Christer; Ryden, Lisa; Loman, Niklas; Malmberg, Martin; Kvist, Anders; Ehrencrona, Hans; Davies, Helen R.; Borg, Ake; Nik-Zainal, Serena 分享 收藏
Genomic landscape and chronological reconstruction of driver events in multiple myeloma Maura, Francesco; Bolli, Niccolo; Angelopoulos, Nicos; Dawson, Kevin J.; Leongamornlert, Daniel; Martincorena, Inigo; Mitchell, Thomas J.; Fullam, Anthony; Gonzalez, Santiago; Szalat, Raphael; Abascal, Federico; Rodriguez-Martin, Bernardo; Samur, Mehmet Kemal; Glodzik, Dominik; Roncador, Marco; Fulciniti, Mariateresa; Tai, Yu Tzu; Minvielle, Stephane; Magrangeas, Florence; Moreau, Philippe; Corradini, Paolo; Anderson, Kenneth C.; Tubio, Jose M. C.; Wedge, David C.; Gerstung, Moritz; Avet-Loiseau, Herve; Munshi, Nikhil; Campbell, Peter J. 分享 收藏
A plug-and-play infrastructure for scalable bioinformatics operations Medina-Martinez, Juan S.; Arango-Ossa, Juan E.; Gundem, Gunes; Levine, Max F.; Patel, Minal; Farnoud, Noushin R.; Yellapantula, Venkata D.; Teng, Gao; Mccarter, Joseph G.; Bernard, Elsa; Rapaport, Franck; Glodzik, Dominik; Levine, Ross L.; Kung, Andrew; Papaemmanuil, Elli 分享 收藏
Oncologic therapy for solid tumors alters the risk of clonal hematopoiesis Bolton, Kelly; Ptashkin, Ryan; Braunstein, Lior; Gao, Teng; Devlin, Sean M.; Kelly, Daniel; Coombs, Catherine; Patel, Minal; Moarii, Matahi; Bernard, Elsa; Berthon, Antonin; Boucai, Laura; Glodzik, Dominik; Martin, Axel; Stadler, Zsofia; Walsh, Michael; Mandelker, Diana; Patel, Akshar; Schulman, Jessica; Gundem, Gunes; Syed, Aijazuddin; Arcila, Maria; Solit, David B.; Robson, Mark E.; Ladanyi, Marc; Lee, Choonsik; Philip, John; Bajorin, Dean; Garcia-Closas, Montserrat; Gardos, Stuart; Hyman, David; Tallman, Martin; Yabe, Mariko; Offit, Kenneth; Scher, Howard; Klimek, Virginia; Diaz, Luis; Chatterjee, Nilanjan; Berger, Michael F.; Morton, Lindsay; Levine, Ross; Zehir, Ahmet; Papaemmanuil, Elli 分享 收藏
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