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K

Karl Herrup

university of pittsburgh

75H指数
324论文数
3.2W被引数
收录论文 76
发表时间
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Effects of damaged astrocytes on DNA damage and repair in human neurons: Implications for Alzheimer's disease受损星形胶质细胞对人神经元DNA损伤和修复的影响：对阿尔茨海默病的启示
errJOURNAL OF ALZHEIMERS DISEASE
IF3.1
err2026-08-11
err0
PREAI
errStarr Welty; Michael Bagnell; Fulin Ma; Karl Herrup; Arthur Samuel Levine
err分享
err收藏
Behavior of neural networks in culture suggest that sporadic and genetic forms of Alzheimer's disease may not be equivalent神经网络的培养行为表明，阿尔茨海默病的散发性和遗传性形式可能并不等同
erralzheimer's & dementia
IF0
err2026-05-26
err0
errOAAI
errFulin Ma; Himanshu Akolkar; Ryad Benosman; Karl Herrup
err分享
err收藏
CDK3 induces neuronal death and brain atrophy in Alzheimer’s diseaseCDK3在阿尔茨海默病中诱导神经元死亡和脑萎缩
errNature Aging
IF19.4
err2025-12-19
err0
PREAI
errKai Zhuang; Liu Zi; Xiao Su; Chen Hu; Xinrui Li; Shuzhong Wang; Yujun Xia; Bo Wu; Yuemin Su; Shaokun Chen; Haojie Li; Siqi Wang; Mengdan Wang; Jieyin Li; Wenting Xie; Yanbing Chen; Lige Leng; Huifang Li; Li Zhong; Jiechao Zhou; Yan Liu; Qingsong Liu; Karl Herrup; Jie Zhang
err分享
err收藏
Perimenopausal state oestradiol to progesterone imbalance drives Alzheimer’s risk via ERRα dysregulation and energy dyshomeostasis围绝经状态下的雌二醇与孕酮失衡通过ERRα失调和能量稳态失调驱动阿尔茨海默病风险
errNature Communications
IF15.7
err2025-11-22
err0
errOAAI
errJacquelyne Ka-Li Sun; Amy Zexuan Peng; Ronald P. Hart; Karl Herrup; Deng WU; Genper Chi-Ngai Wong; Kim Hei-Man Chow
err分享
err收藏
Alpha-ketoglutarate mitigates insulin resistance and metabolic inflexibility in a mouse model of Ataxia-Telangiectasiaα-酮戊二酸缓解共济失调毛细血管扩张症小鼠模型中的胰岛素抵抗和代谢僵化
errNature Communications
IF15.7
err2025-10-21
err0
errOAAI
errJacquelyne Ka-Li Sun; Ronald P. Hart; Karl Herrup; Amy Zexuan Peng; Genper Chi-Ngai Wong; Deng Wu; Kin-Ming Kwan; Kim Hei-Man Chow
err分享
err收藏
ATM deficiency drives phenotypic diversity and Purkinje cell degeneration in a macaque model of ataxia-telangiectasiaATM缺陷驱动共济失调-毛细血管扩张症灵长类模型中的表型多样性和浦肯野细胞退化
errCell Reports Medicine
IF10.6
err2025-09-16
err0
errOAAI
errKaiyu Xu; Ying Zhang; Yongxuan Chen; Xiaojia Zhu; Yu Li; Longbao Lv; Xiechao He; Zhengfei Hu; Yifan Li; Maosen Ye; Dewei Jiang; Zhanlong He; Weihua Jin; Yanyan Li; Xiaomei Yu; Deng-Feng Zhang; Karl Herrup; Ping Zheng; Yong-Gang Yao; Dong-Dong Wu; Jiali Li
err分享
err收藏
Eye movement patterns drive stress reduction during Japanese garden viewing注视日式庭园时的眼动模式可驱动压力减轻
errFRONTIERS IN NEUROSCIENCE
IF3.2
err2025-05-15
err0
errOAAI
errGoto, Seiko; Takase, Hiroki; Yamaguchi, Keita; Kato, Tomoki; Sun, Minkai; Koga, Aoi; Liang, Tiankai; Poy, Isamu A.; Herrup, Karl
err分享
err收藏
The mitochondrial long non-coding RNA lncMtloop regulates mitochondrial transcription and suppresses Alzheimer's disease线粒体长链非编码RNA lncMtloop调节线粒体转录并抑制阿尔茨海默氏病
errEMBO JOURNAL
IF8.3
err2024-10-18
err0
errOAAI
errXiong, Wandi; Xu, Kaiyu; Sun, Jacquelyne Ka-Li; Liu, Siling; Zhao, Baizhen; Shi, Jie; Herrup, Karl; Chow, Hei-Man; Lu, Lin; Li, Jiali
err分享
err收藏
White matter hyperintensity genetic risk factor TRIM47 regulates autophagy in brain endothelial cells
errFASEB JOURNAL
IF4.2
err2024-09-27
err0
errOAAI
errYeung, Sunny Hoi-Sang; Lee, Ralph Hon-Sun; Cheng, Gerald Wai-Yeung; Ma, Iris Wai-Ting; Kofler, Julia; Kent, Candice; Ma, Fulin; Herrup, Karl; Fornage, Myriam; Arai, Ken; Tse, Kai-Hei
err分享
err收藏
Donanemab, another anti-Alzheimer ' s drug with risk and uncertain benefitDonanemab，另一种具有风险和不确定益处的抗阿尔茨海默氏症药物
errAGEING RESEARCH REVIEWS
IF12.4
err2024-08-01
err4
PREAI
errHoilund-Carlsen, Poul F.; Alavi, Abass; Barrio, Jorge R.; Castellani, Rudolph J.; Costa, Tommaso; Herrup, Karl; Kepp, Kasper P.; Neve, Rachael L.; Perry, George; Revheim, Mona-Elisabeth; Robakis, Nikolaos K.; Sensi, Stefano L.; Vissel, Bryce
err分享
err收藏
DNA Damage and Senescence in the Aging and Alzheimer's Disease Cortex Are Not Uniformly Distributed
errBIOMEDICINES
IF3.9
err2024-06-14
err0
errOAAI
errGutta, Gnanesh; Mehta, Jay; Kingston, Rody; Xie, Jiaan; Brenner, Eliana; Ma, Fulin; Herrup, Karl
err分享
err收藏
Recalibrating the Risk-Benefit Profiles of Lecanemab and Donanemab: Scales, Immunoreactivity, and Changes in Amyloid-β42
errJOURNAL OF ALZHEIMERS DISEASE
IF3.1
err2024-05-02
err5
PREAI
errEspay, Alberto J.; Herrup, Karl; Imbimbo, Bruno P.; Kepp, Kasper P.; Daly, Timothy
err分享
err收藏
Revision of Alzheimer's diagnostic criteria or relocation of the Potemkin village修订阿尔茨海默氏症的诊断标准或搬迁Potemkin村
errAGEING RESEARCH REVIEWS
IF12.4
err2024-01-01
err4
errOAAI
errHoilund-Carlsen, Poul F.; Alavi, Abass; Barrio, Jorge R.; Castellani, Rudolph J.; Costa, Tommaso; Herrup, Karl; Kepp, Kasper P.; Neve, Rachael L.; Perry, George; Robakis, Nikolaos K.; Revheim, Mona -Elisabeth; Sensi, Stefano L.; Vissel, Bryce
err分享
err收藏
The proteinopenia hypothesis: Loss of Aβ42 and the onset of Alzheimer's Disease
errAGEING RESEARCH REVIEWS
IF12.4
err2023-12-01
err9
errOAAI
errEspay, Alberto J.; Herrup, Karl; Kepp, Kasper P.; Daly, Timothy
err分享
err收藏
The Anti-Amyloid Monoclonal Antibody Lecanemab: 16 Cautionary Notes抗淀粉样蛋白单克隆抗体Lecanemab: 16个注意事项
errJOURNAL OF ALZHEIMERS DISEASE
IF3.1
err2023-07-18
err29
errOAAI
errKepp, Kasper P.; Sensi, Stefano L.; Johnsen, Kasper B.; Barrio, Jorge R.; Hoilund-Carlsen, Poul F.; Neve, Rachael L.; Alavi, Abass; Herrup, Karl; Perry, George; Robakis, Nikolaos K.; Vissel, Bryce; Espay, Alberto J.
err分享
err收藏
A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis
errNATURE CELL BIOLOGY
IF19.1
err2023-02-27
err11
errOAAI
errZou, Han; Poore, Bradley; Brown, Emily E.; Qian, Jieqi; Xie, Bin; Asimakidou, Evridiki; Razskazovskiy, Vladislav; Ayrapetian, Deanna; Sharma, Vaibhav; Xia, Shunjin; Liu, Fei; Chen, Apeng; Guan, Yongchang; Li, Zhengwei; Wanggou, Siyi; Saulnier, Olivier; Ly, Michelle; Fellows-Mayle, Wendy; Xi, Guifa; Tomita, Tadanori; Resnick, Adam C.; Mack, Stephen C.; Raabe, Eric H.; Eberhart, Charles G.; Sun, Dandan; Stronach, Beth E.; Agnihotri, Sameer; Kohanbash, Gary; Lu, Songjian; Herrup, Karl; Rich, Jeremy N.; Gittes, George K.; Broniscer, Alberto; Hu, Zhongliang; Li, Xuejun; Pollack, Ian F.; Friedlander, Robert M.; Hainer, Sarah J.; Taylor, Michael D.; Hu, Baoli
err分享
err收藏
Apolipoprotein E ε4 Mediates Myelin Breakdown by Targeting Oligodendrocytes in Sporadic Alzheimer Disease
errJOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
IF3
err2022-07-01
err16
errOAAI
errCheng, Gerald Wai-Yeung; Mok, Kingston King-Shi; Yeung, Sunny Hoi-Sang; Kofler, Julia; Herrup, Karl; Tse, Kai-Hei
err分享
err收藏
Small-World Networks and Their Relationship With Hippocampal Glutamine/Glutamate Concentration in Healthy Adults With Varying Genetic Risk for Alzheimer's Disease
errJOURNAL OF MAGNETIC RESONANCE IMAGING
IF3.5
err2021-05-03
err5
errOAAI
errZhang, Hui; Chiu, Pui W.; Ip, Isaac; Liu, Tianyin; Wong, Gloria H. Y.; Song, You-Qiang; Wong, Savio W. H.; Herrup, Karl; Mak, Henry K. F.
err分享
err收藏
Selective loss of 5hmC promotes neurodegeneration in the mouse model of Alzheimer's disease
errFASEB JOURNAL
IF4.2
err2020-10-15
err35
PREAI
errZhang, Ying; Zhang, Zhongyu; Li, Lianwei; Xu, Kaiyu; Ma, Zhanshan; Chow, Hei-Man; Herrup, Karl; Li, Jiali
err分享
err收藏
ATM loss disrupts the autophagy-lysosomal pathway
errAUTOPHAGY
IF14.3
err2020-08-14
err37
errOAAI
errCheng, Aifang; Tse, Kai-Hei; Chow, Hei-Man; Gan, Yunqiao; Song, Xuan; Ma, Fulin; Qian, Yi Xuan Yvonne; She, Weiyi; Herrup, Karl
err分享
err收藏

研究方向

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合作学者
合作期刊
D
David S. Knopman
H 指数: 188 · 论文数: 2.1K
K
Kristine Yaffe
H 指数: 156 · 论文数: 1.4K
G
George Perry
H 指数: 152 · 论文数: 1.5K
R
Reisa A. Sperling
H 指数: 151 · 论文数: 1.2K
E
Eric M. Reiman
H 指数: 150 · 论文数: 1.2K
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