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The pivotal role of von Willebrand factor binding to platelet αIIbβ3 in stabilizing the formation of a platelet plug at sites of injury von Willebrand因子与血小板αIIbβ3结合在稳定损伤部位血小板栓子形成中的关键作用 Shi, Qizhen; Mattson, Jeremy G.; Morateck, Patricia A.; Christopherson, Pamela A.; Schroeder, Jocelyn A.; Fahs, Scot A.; Rapten, Jessica; Schulte, Marie L.; Weiler, Hartmut; Zhu, Jieqing; Haberichter, Sandra L.; Flood, Veronica H.; Montgomery, Robert R. 分享 收藏
Coagulation proteases modulate nucleic acid uptake and cGAS-STING-IFN induction in the tumor microenvironment 凝血蛋白酶调控肿瘤微环境中的核酸摄取和cGAS-STING-IFN诱导 Wilgenbus, Petra; Pott, Jennifer; Pagel, Sven; Witzler, Claudius; Royce, Jennifer; Marini, Federico; Reyda, Sabine; Madhusudhan, Thati; Kindler, Thomas; Hausen, Anne; Gaida, Matthias M.; Weiler, Hartmut; Ruf, Wolfram; Graf, Claudine 分享 收藏
Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma Bansal, Shivani; Li, Yaoxiang; Bansal, Sunil; Klotzbier, William; Singh, Baldev; Jayatilake, Meth; Sridharan, Vijayalakshmi; Fernandez, Jose A.; Griffin, John H.; Weiler, Hartmut; Boerma, Marjan; Cheema, Amrita K. 分享 收藏
TF-FVIIa PAR2-β-Arrestin Signaling Sustains Organ Dysfunction in Coxsackievirus B3 Infection of Mice Kespohl, Meike; Goetzke, Carl Christoph; Althof, Nadine; Bredow, Clara; Kelm, Nicolas; Pinkert, Sandra; Bukur, Thomas; Bukur, Valesca; Grunz, Kristin; Kaur, Dilraj; Heuser, Arnd; Muelleder, Michael; Sauter, Martina; Klingel, Karin; Weiler, Hartmut; Berndt, Nikolaus; Gaida, Matthias M.; Ruf, Wolfram; Beling, Antje 分享 收藏
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Protease- and cell type-specific activation of protease-activated receptor 2 in cutaneous inflammation Fleischer, Maria Isabel; Roehrig, Nadine; Raker, Verena K.; Springer, Juliane; Becker, Detlef; Ritz, Sandra; Bros, Matthias; Stege, Henner; Haist, Maximilian; Grabbe, Stephan; Haub, Jessica; Becker, Christian; Reyda, Sabine; Disse, Jennifer; Schmidt, Talkea; Mahnke, Karsten; Weiler, Hartmut; Ruf, Wolfram; Steinbrink, Kerstin 分享 收藏
A novel mouse model of type 2N VWD was developed by CRISPR/Cas9 gene editing and recapitulates human type 2N VWD Shi, Qizhen; Fahs, Scot A.; Mattson, Jeremy G.; Yu, Hongyin; Perry, Crystal L.; Morateck, Patricia A.; Schroeder, Jocelyn A.; Rapten, Jessica; Weiler, Hartmut; Montgomery, Robert R. 分享 收藏
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A thrombin-PAR1/2 feedback loop amplifies thromboinflammatory endothelial responses to the viral RNA analogue poly(I:C) Subramaniam, Saravanan; Ogoti, Yamini; Hernandez, Irene; Zogg, Mark; Botros, Fady; Burns, Robert; DeRousse, Jacob T.; Dockendorff, Chris; Mackman, Nigel; Antoniak, Silvio; Fletcher, Craig; Weiler, Hartmut 分享 收藏
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Macrophage protease-activated receptor 2 regulates fetal liver erythropoiesis in mice Saffarzadeh, Mona; Grunz, Kristin; Nguyen, T. Son; Lee, Young K.; Kitano, Maki; Danckwardt, Sven; Rodrigues, Carina D. S.; Weiler, Hartmut; Reyda, Sabine; Ruf, Wolfram 分享 收藏
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Role of thrombomodulin expression on hematopoietic stem cells Basu, Sreemanti; Liang, Hai Po Helena; Hernandez, Irene; Zogg, Mark; Fields, British; May, Jennifer; Ogoti, Yamini; Wyseure, Tine; Mosnier, Laurent O.; Burns, Robert T.; Carlson, Karen; Weiler, Hartmut 分享 收藏
Synthesis and initial pharmacology of dual-targeting ligands for putative complexes of integrin αVβ3 and PAR2 Majewski, Mark W.; Gandhi, Disha M.; Holyst, Trudy; Wang, Zhengli; Hernandez, Irene; Rosas, Ricardo, Jr.; Zhu, Jieqing; Weiler, Hartmut; Dockendorff, Chris 分享 收藏
A rat model of severe VWD by elimination of the VWF gene using CRISPR/Cas9 Garcia, Jessica; Flood, Veronica H.; Haberichter, Sandra L.; Fahs, Scot A.; Mattson, Jeremy G.; Geurts, Aron M.; Zogg, Mark; Weiler, Hartmut; Shi, Qizhen; Montgomery, Robert R. 分享 收藏