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J

Jeffrey N. Savas

northwestern university

42H指数
165论文数
1.1W被引数
收录论文 73
发表时间
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Conditional Modeling of GNAO1 Disorder Dissociates Circuit Specific Contributions to Pathology and Rationalizes Ameliorative StrategiesGNAO1紊乱的条件性建模分离了病理学中回路特异性的贡献，并阐明了改善策略的合理性。
errMovement Disorders
IF7.6
err2026-03-28
err0
errOAAI
errGloria Brunori PhD; Stefano Zucca PhD; Colten K. Lankford PhD; Yi-Zhi Wang PhD; Marianna Franco BSc; Nina A. Alekseeva BSc; Sevinj Ahmedova BSc; Han My Van PhD; Jeffrey N. Savas PhD; Kirill A. Martemyanov PhD
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Response dynamics of discrete subiculum→retrosplenial cortex projections underlying trace fear conditioning离散下丘→扣带回后部皮层投射在痕迹恐惧条件反射中的响应动力学
erriScience
IF4.1
err2026-03-13
err0
errOAAI
errThomas E. Bassett; Yi-Zhi Wang; Elizabeth M. Wood; Hui Zhang; Zorica Petrovic; Vivien Prifti; Vladimir Jovasevic; Naoki Yamawaki; Lynn Ren; Natalia Khalatyan; Viktoriya Grayson; Jeffrey N. Savas; Jelena Radulovic; Ana Cicvaric
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Levetiracetam prevents Aβ production through SV2a-dependent modulation of APP processing in Alzheimer’s disease models左乙拉西坦通过SV2a依赖性调节阿尔茨海默病模型中APP加工来预防Aβ的产生
errScience Translational Medicine
IF14.6
err2026-02-11
err0
PREAI
errNalini R. Rao; Ivan Santiago-Marrero; Olivia DeGulis; Toshihiro Nomura; Kritika Goyal; SeungEun Lee; Timothy J. Hark; Justin C. Dynes; Emily X. Dexter; Maciej Dulewicz; Junyue Ge; Arun Upadhyay; Eugenio F. Fornasiero; Robert Vassar; Jörg Hanrieder; Anis Contractor; Jeffrey N. Savas
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Reduction of RAD23A extends lifespan and mitigates pathology in a mouse model of TDP-43 proteinopathyRAD23A的减少延长了寿命并减轻了TDP-43蛋白病小鼠模型中的病理学表现。
errNature Communications
IF15.7
err2026-01-16
err0
errOAAI
errXueshui Guo; Ravindra Singh Prajapati; Jiyeon Chun; Insuk Byun; Kamil K. Gebis; Yi-Zhi Wang; Karen Ling; Casey Dalton; Jeff A. Blair; Anahid Hamidianjahromi; Gemma Bachmann; Frank Rigo; Paymaan Jafar-nejad; Jeffrey N. Savas; Min Jae Lee; Jemeen Sreedharan; Robert G. Kalb
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Considerations for Spatial Omics, Metabolite Analyses, and Tissue-Harvesting Artifacts空间组学、代谢物分析和组织采集人工制品的考量
errJournal of Neurochemistry
IF4
err2025-12-05
err0
errOAAI
errJörg Hanrieder; Ramon Sun; Shane R. Ellis; Jens Pahnke; Jeffrey N. Savas
err分享
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Genetic and proteomic analysis identifies BAG3 as an amyloid-responsive regulator of neuronal proteostasis遗传和蛋白质组学分析确定BAG3是神经元蛋白质稳态的淀粉样蛋白应答调节因子
errActa Neuropathologica
IF9.3
err2025-10-14
err0
errOAAI
errZachary M. Augur; Garrett M. Fogo; Mason R. Arbery; Yi-Chen Hsieh; Nalini R. Rao; Kritika Goyal; Emily Dexter; David A. Bennett; Jeffrey N. Savas; Andrew M. Stern; Tracy L. Young-Pearse
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Isotope-encoded spatial biology identifies plaque-age-dependent maturation and synaptic loss in an Alzheimer’s disease mouse model同位素编码空间生物学识别阿尔茨海默病小鼠模型中斑块年龄依赖性的成熟和突触丢失
errNature Communications
IF15.7
err2025-09-01
err0
errOAAI
errJack I. Wood; Maciej Dulewicz; Alicja Szadziewska; Sophia Weiner; Junyue Ge; Katie Stringer; Sneha Desai; Lydia Fenson; Diana Piotrowska; Gunnar Brinkmalm; Srinivas Koutarapu; Haady B. Hajar; Kaj Blennow; Henrik Zetterberg; Damian M. Cummings; Jeffrey N. Savas; Frances A. Edwards; Jörg Hanrieder
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Influenza A virus infection during pregnancy increases transfer of maternal bloodborne molecules to fetal tissues妊娠期流感A病毒感染会增加母体血液分子向胎儿组织的转移
errbrain behavior and immunity
IF0
err2025-08-06
err0
errOAAI
errRafael J. Gonzalez-Ricon; Ashley M. Otero; Izan Chalen; Jeffrey N. Savas; Shakirat Adetunji; Adrienne M. Antonson
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DELTA: a method for brain-wide measurement of synaptic protein turnover reveals localized plasticity during learningDELTA：一种用于全脑测量突触蛋白质周转的方法，揭示了学习期间的区域性可塑性
errNATURE NEUROSCIENCE
IF20
err2025-03-31
err1
errOAAI
errMohar, Boaz; Michel, Gabriela; Wang, Yi-Zhi; Hernandez, Veronica; Grimm, Jonathan B.; Park, Jin-Yong; Patel, Ronak; Clarke, Morgan; Brown, Timothy A.; Bergmann, Cornelius; Gebis, Kamil K.; Wilen, Anika P.; Liu, Bian; Johnson, Richard; Graves, Austin; Tchumatchenko, Tatjana; Savas, Jeffrey N.; Fornasiero, Eugenio F.; Huganir, Richard L.; Tillberg, Paul W.; Lavis, Luke D.; Svoboda, Karel; Spruston, Nelson
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A novel, rapidly progressive ataxia due to a spontaneous Myo5a mutation in mice impairs transport proteins and alters mitochondria
errFASEB JOURNAL
IF4.2
err2025-03-15
err0
errOAAI
errTelenson, Alexander M.; Hsieh, Ryan R.; Cowen, Gabrielle J.; Sode, Eoin P.; Kwon, Jason M.; Vo, Andy H.; Hadhazy, Michele; Page, Patrick G.; Rao, Nalini R.; Pesce, Lorenzo; Demonbreun, Alexis R.; Puckelwartz, Megan J.; Savas, Jeffrey N.; Mcnally, Elizabeth M.
err分享
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Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan
errELIFE
IF0
err2024-10-31
err4
errOAAI
errBomba-Warczak, Ewa K.; Velez, Karen M.; Zhou, Luhan T.; Guillermier, Christelle; Edassery, Seby; Steinhauser, Matthew L.; Savas, Jeffrey N.; Duncan, Francesca E.
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Do Perineuronal Nets Stabilize the Engram of a Synaptic Circuit?神经末梢网是否能稳定突触回路的Engram？
errCELLS
IF5.2
err2024-09-29
err0
errOAAI
errLev-Ram, Varda; Lemieux, Sakina Palida; Deerinck, Thomas J.; Bushong, Eric A.; Perez, Alex J.; Pritchard, Denise R.; Toyama, Brandon H.; Park, Sung Kyu R.; McClatchy, Daniel B.; Savas, Jeffrey N.; Whitney, Michael; Adams, Stephen R.; Ellisman, Mark H.; Yates III, John; Tsien, Roger Y.
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A novel gene family underlying cancer cell resilience一种支持癌细胞韧性的新型基因家族
errANNALS OF ONCOLOGY
IF65.4
err2024-09-01
err0
PREAI
errAmici, D. R.; Alhayek, S.; Cingoz, H.; Wilen, A.; Wang, Y-Z.; Savas, J.; Mendillo, M.
err分享
err收藏
Leveraging biotin-based proximity labeling to identify cellular factors governing early alphaherpesvirus infection
errMBIO
IF4.7
err2024-08-14
err2
errOAAI
errQuan, Jenai; Fan, Qing; Simons, Lacy M.; Smukowski, Samuel N.; Pegg, Caitlin; Longnecker, Richard; Savas, Jeffrey N.; Hultquist, Judd F.; Smith, Gregory A.
err分享
err收藏
The Outer Mitochondrial Membrane Protein Mtch2 Regulates Cardiac Metabolic Homeostasis and Body Mass
errCIRCULATION RESEARCH
IF16.2
err2024-08-02
err0
PREAI
errStachowski, Marisa; Monroe, Tanner; Hadhazy, Michele; Bomba-Warczak, Ewa; Savas, Jeffrey; Puckelwartz, Megan; McNally, Elizabeth
err分享
err收藏
Neuron type-specific proteomics reveals distinct Shank3 proteoforms in iSPNs and dSPNs lead to striatal synaptopathy in Shank3B -/- mice (Mar, 10.1038/s41380-024-02493-w, 2024)
errMOLECULAR PSYCHIATRY
IF10.1
err2024-03-28
err0
errOAAI
errWang, Yi-Zhi; Perez-Rosello, Tamara; Smukowski, Samuel N.; Surmeier, D. James; Savas, Jeffrey N.
err分享
err收藏
Neuron type-specific proteomics reveals distinct Shank3 proteoforms in iPSNs and dSPNs lead to striatal synaptopathy in Shank3B-/- mice
errMOLECULAR PSYCHIATRY
IF10.1
err2024-03-14
err3
errOAAI
errWang, Yi-Zhi; Perez-Rosello, Tamara; Smukowski, Samuel N.; Surmeier, D. James; Savas, Jeffrey N.
err分享
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Tight regulation of a nuclear HAPSTR1-HUWE1 pathway essential for mammalian life
errLIFE SCIENCE ALLIANCE
IF2.9
err2024-03-07
err0
errOAAI
errAmici, David R.; Alhayek, Sammy; Klein, Austin T.; Wang, Yi-Zhi; Wilen, Anika P.; Song, Weimin; Zhu, Pei; Thakkar, Abhishek; King, McKenzi A.; Steffeck, Adam W. T.; Alasady, Milad J.; Peek, Clara; Savas, Jeffrey N.; Mendillo, Marc L.
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Notch receptor-ligand binding facilitates extracellular vesicle-mediated neuron-to-neuron communication
errCELL REPORTS
IF6.9
err2024-02-01
err0
errOAAI
errWang, Yi-Zhi; Castillon, Charlotte C. M.; Gebis, Kamil K.; Bartom, Elizabeth T.; d'Azzo, Alessandra; Contractor, Anis; Savas, Jeffrey N.
err分享
err收藏
Derailed protein turnover in the aging mammalian brain
errMOLECULAR SYSTEMS BIOLOGY
IF7.7
err2024-01-05
err6
errOAAI
errRao, Nalini R.; Upadhyay, Arun; Savas, Jeffrey N.
err分享
err收藏

研究方向

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合作学者
合作期刊
F
Fred H. Gage
H 指数: 219 · 论文数: 1.1K
K
Kaj Blennow
H 指数: 214 · 论文数: 3.6K
D
David A. Bennett
H 指数: 197 · 论文数: 2.3K
H
Henrik Zetterberg
H 指数: 190 · 论文数: 3.7K
J
John R. Yates
H 指数: 188 · 论文数: 1.5K
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