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M

Michael Gotthardt

german centre for cardiovascular research

46H指数
149论文数
1.1W被引数
收录论文 93
发表时间
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Multi-omics insight into cardiac myofibril remodeling in post-prandial Burmese pythons多组学对缅甸蟒餐后心肌肌原纤维重塑的见解
errCommunications Biology
IF5.1
err2026-09-30
err0
errOAAI
errThomas G. Martin; Lorena Suarez-Artiles; Kathleen C. Woulfe; Elise G. Melhedegaard; Yuxiao Tan; Dakota R. Hunt; Bruce E. Kirkpatrick; Lia Nguyen; Joseph Lee; Isabella Laskey; Kristi S. Anseth; Julien Ochala; Michael Gotthardt; Philipp Mertins; Leslie A. Leinwand
err分享
err收藏
The role of circulating polyunsaturated fatty acids in atrial fibrillation and atrial cardiomyopathy a machine learning-informed structural modelling approach循环多不饱和脂肪酸在心房颤动和心房心肌病中的作用：一种基于机器学习的结构建模方法
errEuropean Journal of Heart Failure
IF10.8
err2026-07-28
err0
PREAI
errJakob Versnjak; Giuseppe Trimarchi; Anna Foryst-Ludwig; Benjamin Wild; Kilian Kuehne; Gabriele G Schiattarella; Michael Gotthardt; Roland Eils; Titus Kuehne; Ulrich Kintscher; Marcus Kelm⁠
err分享
err收藏
Targeting intracellular cholesterol imbalance rescues sarcomere–ER contact site signaling and ER remodeling in dilated cardiomyopathy靶向细胞内胆固醇失衡可挽救扩张型心肌病的肌节-ER接触部位信号和ER重塑
errSignal Transduction and Targeted Therapy
IF52.7
err2026-06-17
err0
errOAAI
errNadezda Ignatyeva; Cleophas Cheruiyot; Hafiza Nosheen Saleem; Ruheen Wali; Daria Plota; Wenjing Zhang; Sophie Schön; Soeren Brandenburg; Zhengyi Yang; Anna Steyer; Henning Urlaub; Torsten Rasmussen; Jens Mogensen; Julius Ryan D. Pronto; Yannic Döring; Michael H. Radke; Halyna Shcherbata; Stephan E. Lehnart; Andreas Janshoff; Samuel Sossalla; Torben Ruhwedel; Wiebke Moebius; Karl Toischer; Britta Brügger; Volker Haucke; Michael Gotthardt; Niels Voigt; Antje Ebert
err分享
err收藏
RBM20 isoform regulation by independent transcription start sites adapts alternative splicing in development and diseaseRBM20异构体通过独立转录起始位点调控适应发育和疾病中的选择性剪接
errNature Communications
IF15.7
err2026-05-23
err0
errOAAI
errMichael H. Radke; Victor Badillo Lisakowski; Stefan Meinke; Thiago Britto-Borges; Valentin Schneider-Lunitz; Oliver Hummel; Sebastiaan van Heesch; Jorge Ruiz Orera; Norbert Hubner; Henk Granzier; Christoph Dieterich; Michael Gotthardt
err分享
err收藏
Alternative splicing dynamics during human cardiac development in vivo and in vitro体内和体外人类心脏发育过程中的选择性剪接动态
errStem Cell Reports
IF5.1
err2026-01-02
err0
errOAAI
errBeatriz Gomes-Silva; Marta Furtado; Marta Ribeiro; Sandra Martins; Teresa Carvalho; André Ventura-Gomes; Henrike Maatz; Pragati Parakkat; Claudia Crocini; Michael Gotthardt; Rosina Savisaar; Maria Carmo-Fonseca
err分享
err收藏
Prime Editing Corrects The Dilated Cardiomyopathy Causing RBM20-P633L-Mutation in Human CardiomyocytesPrime Editing 纠正了导致人类心肌细胞中 RBM20-P633L-突变的心肌扩张症
errMolecular Therapy Nucleic Acids
IF6.1
err2025-10-06
err0
errOAAI
errAlexandra Roman; Anja Zimmer; Michael Gotthardt; Lars M. Steinmetz; Ralf Kühn; Tu Dang
err分享
err收藏
Rbm20 antisense oligonucleotides alleviate diastolic dysfunction in a mouse model of cardiometabolic heart failure (HFpEF)Rbm20 反义寡核苷酸缓解代谢性心力衰竭（HFpEF）小鼠模型中的舒张功能障碍
errCARDIOVASCULAR RESEARCH
IF13.3
err2025-10-01
err0
PREAI
errMethawasin, Mei; Meinke, Stefan; Radke, Michael H.; Farman, Gerrie P.; Hourani, Zaynab; Smith III, John E.; Guo, Wei; Granzier, Henk; Gotthardt, Michael
err分享
err收藏
Deep phenotyping of heart failure with preserved ejection fraction through multi-omics integration通过多组学整合对射血分数保留的心力衰竭进行深度表型分析
errEuropean Journal of Heart Failure
IF10.8
err2025-09-22
err0
errOAAI
errJakob Versnjak; Titus Kuehne; Pauline Fahjen; Nina Jovanovic; Ulrike Löber; Gabriele G. Schiattarella; Nicola Wilck; Holger Gerhardt; Dominik N. Müller; Frank Edelmann; Philipp Mertins; Roland Eils; Michael Gotthardt; Sofia K. Forslund; Benjamin Wild; Marcus Kelm
err分享
err收藏
Visualizing sarcomere and cellular dynamics in skeletal muscle to improve cell therapies
errELIFE
IF0
err2024-12-17
err0
errOAAI
errHuettemeister, Judith; Rudolph, Franziska; Radke, Michael H.; Fink, Claudia; Friedrich, Dhana; Preibisch, Stephan; Falcke, Martin; Wagner, Eva; Lehnart, Stephan E.; Gotthardt, Michael
err分享
err收藏
Titin's cardiac-specific N2B element is critical to mechanotransduction during volume overload of the heart
errJOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
IF4.7
err2024-06-01
err3
errOAAI
errStrom, Joshua; Bull, Mathew; Gohlke, Jochen; Saripalli, Chandra; Methawasin, Mei; Gotthardt, Michael; Granzier, Henk
err分享
err收藏
SERCA2a microdomain cAMP changes in heart failure with preserved ejection fraction
errCARDIOVASCULAR RESEARCH
IF13.3
err2024-02-09
err1
errOAAI
errGotthardt, Michael; Lehnart, Stephan E.
err分享
err收藏
Loss of Cardiac Splicing Regulator RBM20 Is Associated With Early-Onset Atrial Fibrillation心脏剪接调节因子RBM20的缺失与早发心房颤动相关
errJACC-BASIC TO TRANSLATIONAL SCIENCE
IF7.2
err2024-02-01
err7
errOAAI
errVad, Oliver B.; Angeli, Elisavet; Liss, Martin; Ahlberg, Gustav; Andreasen, Laura; Christophersen, Ingrid E.; Hansen, Camilla C.; Moller, Sophie; Hellsten, Ylva; Haunsoe, Stig; Tveit, Arnljot; Svendsen, Jesper H.; Gotthardt, Michael; Lundegaard, Pia R.; Olesen, Morten S.
err分享
err收藏
Mislocalization of pathogenic RBM20 variants in dilated cardiomyopathy is caused by loss-of-interaction with Transportin-3
errNATURE COMMUNICATIONS
IF15.7
err2023-07-18
err9
errOAAI
errKornienko, Julia; Rodriguez-Martinez, Marta; Fenzl, Kai; Hinze, Florian; Schraivogel, Daniel; Grosch, Markus; Tunaj, Brigit; Lindenhofer, Dominik; Schraft, Laura; Kueblbeck, Moritz; Smith, Eric; Mao, Chad; Brown, Emily; Owens, Anjali; Saguner, Ardan M. M.; Meder, Benjamin; Parikh, Victoria; Gotthardt, Michael; Steinmetz, Lars M. M.
err分享
err收藏
Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy
errNATURE COMMUNICATIONS
IF15.7
err2023-06-22
err16
errOAAI
errGrosch, Markus; Schraft, Laura; Chan, Adrian; Kuechenhoff, Leonie; Rapti, Kleopatra; Ferreira, Anne-Maud; Kornienko, Julia; Li, Shengdi; Radke, Michael H.; Kraemer, Chiara; Clauder-Muenster, Sandra; Perlas, Emerald; Backs, Johannes; Gotthardt, Michael; Dieterich, Christoph; van den Hoogenhof, Maarten M. G.; Grimm, Dirk; Steinmetz, Lars M.
err分享
err收藏
CAR links hypoxia signaling to improved survival after myocardial infarction
errEXPERIMENTAL AND MOLECULAR MEDICINE
IF12.9
err2023-03-20
err1
errOAAI
errFreiberg, Fabian; Thakkar, Meghna; Hamann, Wiebke; Lopez Carballo, Jacobo; Juettner, Rene; Voss, Felizia K.; Becher, Peter M.; Westermann, Dirk; Tschoepe, Carsten; Heuser, Arnd; Rocks, Oliver; Fischer, Robert; Gotthardt, Michael
err分享
err收藏
Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames
errMOLECULAR CELL
IF16.6
err2023-03-01
err46
errOAAI
errSandmann, Clara-L.; Schulz, Jana F.; Ruiz-Orera, Jorge; Kirchner, Marieluise; Ziehm, Matthias; Adami, Eleonora; Marczenke, Maike; Christ, Annabel; Liebe, Nina; Greiner, Johannes; Schoenenberger, Aaron; Muecke, Michael B.; Liang, Ning; Moritz, Robert L.; Sun, Zhi; Deutsch, Eric W.; Gotthardt, Michael; Mudge, Jonathan M.; Prensner, John R.; Willnow, Thomas E.; Mertins, Philipp; van Heesch, Sebastiaan; Hubner, Norbert
err分享
err收藏
Disease- and sex-specific differences in patients with heart valve disease: a proteome study
errLIFE SCIENCE ALLIANCE
IF2.9
err2023-01-10
err3
errOAAI
errNordmeyer, Sarah; Kraus, Milena; Ziehm, Matthias; Kirchner, Marieluise; Schafstedde, Marie; Kelm, Marcus; Niquet, Sylvia; Stephen, Mariet Mathew; Baczko, Istvan; Knosalla, Christoph; Schapranow, Matthieu-P; Dittmar, Gunnar; Gotthardt, Michael; Falcke, Martin; Regitz-Zagrosek, Vera; Kuehne, Titus; Mertins, Philipp
err分享
err收藏
A single-cell RNA labeling strategy for measuring stress response upon tissue dissociation
errMOLECULAR SYSTEMS BIOLOGY
IF7.7
err2022-12-27
err9
errOAAI
errNeuschulz, Anika; Bakina, Olga; Badillo-Lisakowski, Victor; Olivares-Chauvet, Pedro; Conrad, Thomas; Gotthardt, Michael; Kettenmann, Helmut; Junker, Jan Philipp
err分享
err收藏
The IgCAM CAR Regulates Gap Junction-Mediated Coupling on Embryonic Cardiomyocytes and Affects Their Beating Frequency
errLIFE-BASEL
IF3.4
err2022-12-21
err2
errOAAI
errMatthaeus, Claudia; Juettner, Rene; Gotthardt, Michael; Rathjen, Fritz G.
err分享
err收藏
Epithelial coxsackievirus adenovirus receptor promotes house dust mite-induced lung inflammation
errNATURE COMMUNICATIONS
IF15.7
err2022-10-27
err8
errOAAI
errOrtiz-Zapater, Elena; Bagley, Dustin C.; Hernandez, Virginia Llopis; Roberts, Luke B.; Maguire, Thomas J. A.; Voss, Felizia; Mertins, Philipp; Kirchner, Marieluise; Peset-Martin, Isabel; Woszczek, Grzegorz; Rosenblatt, Jody; Gotthardt, Michael; Santis, George; Parsons, Maddy
err分享
err收藏

研究方向

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