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T

Thomas G. Graeber

university of california
H指数:77
被引数:3.3万

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荣誉奖项

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l-Glutamine in combination with first-line gemcitabine and nab-paclitaxel in advanced pancreatic ductal adenocarcinoma: an open-label, single-arm, phase 1 GlutaPanc trial
Nature Cancer
IF28.5
2026-08-310
OAAI
Jun Gong; Hayato Muranaka; So Yung Choi; Mourad Tighiouart; Shrikant Bhute; Ezinne R. Aja; Jonathan P. Jacobs; Aleksandr Stotland; Jennifer Van Eyk; Omer H. M. Elmadbouh; Mouad Edderkaoui; Sunao Tanaka; Hideki Furuya; Arsen Osipov; Jeremy Lorber; Sandrine Billet; Alexzandra Morris; Johanna ten Hoeve-Scott; Thomas Graeber; Stephen J. Pandol; Andrew Hendifar; Neil A. Bhowmick
The liver regulates ectopic calcification in Abcc6- deficient models of pseudoxanthoma elasticum

肝脏调节假性弹性纤维假黄瘤Abcc6缺陷模型的异位钙化

Journal of Clinical Investigation
IF13.6
2026-05-010
OA
Wang, Yijie; Sun, Baiming; Ma, Feiyang; Tao, Bo; Gu, Yiqian; Zhou, Zhiqiang; Kim, Jason; Zhang, Linlin; Liu, Zhihao; ten Hoeve, Johanna; Stiles, Linsey; del Rio, Lucia Fernandez; Pan, Calvin; Shirihai, Orian; Xu, Shili; Graeber, Thomas G.; Sallam, Tamer; Pellegrini, Matteo; Lusis, Aldons J.; Deb, Arjun
Author Correction: BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR–ABL1 kinase inhibition

作者更正: BCL6使Ph急性淋巴细胞白血病细胞能够BCR-ABL1激酶抑制而存活

Nature
IF48.5
2026-02-180
PRE
Cihangir Duy; Christian Hurtz; Seyedmehdi Shojaee; Leandro Cerchietti; Huimin Geng; Srividya Swaminathan; Lars Klemm; Soo-mi Kweon; Rahul Nahar; Melanie Braig; Eugene Park; Yong-mi Kim; Wolf-Karsten Hofmann; Sebastian Herzog; Hassan Jumaa; H. Phillip Koeffler; J. Jessica Yu; Nora Heisterkamp; Thomas G. Graeber; Hong Wu; B. Hilda Ye; Ari Melnick; Markus Müschen
Discovery and Optimization of Orally Bioavailable Heterobifunctional Degraders of KAT2A/B for the Treatment of Cancer

发现和优化具有口服生物利用度的异双功能KAT2A/B降解剂以用于癌症治疗

Journal of Medicinal Chemistry
IF6.8
2026-02-080
PRE
James Neef; Kimberly S. Straley; Chinmoy Mukherjee; Amol Tipnis; Suleman Riyajsaheb Maujan; Maulasri Bhatta; Sambad Sharma; Sara Sinicropi-Yao; Joe DeBartolo; Andrew J. McRiner; Betty Chan; Henry Wilson; Christina S. Lee; Zied Boudhraa; Mohamed El Ezzy; Mark Bittinger; Laura Jennings Antipov; Thomas G. Graeber; Katharine E. Yen; David S. Millan
Development of a leucine-rich repeat-containing protein 15-targeted radio-immunotheranostic approach to deplete pro-tumorigenic mechanisms and immunotherapy resistance

靶向富含亮氨酸重复蛋白15的放射性免疫治疗诊断方法的开发，以耗竭促肿瘤机制和免疫治疗耐药性

Signal Transduction and Targeted Therapy
IF52.7
2025-09-300
OA
Claire M. Storey; Mohamed Altai; Katharina Lückerath; Wahed Zedan; Henan Zhu; Lara Breuer; Marija Trajkovic-Arsic; Julie Park; Abbie Hasson; Jens Siveke; Diane Abou; Haley Marks; Enna Ulmert; Alexander Ridley; Marcella Safi; Urpo Lamminmäki; Constance Yuen; Susanne Geres; Liqun Mao; Michael Cheng; Sumit K. Subudhi; Bilal A. Siddiqui; Noah Federman; Johannes Czernin; Ken Herrmann; Laurent Bentolila; Xia Yang; Thomas G. Graeber; Robert Damoiseaux; Daniel Thorek; David Ulmert
AUTX-703, A Novel and Potent KAT2A and KAT2B Proteint Degrader, Induces Profound and Persistent Cell State Differentiation and Inhibits Growth in SCLC Model Systems

AUTX-703，一种新型且高效的KAT2A和KAT2B蛋白质降解剂，可诱导SCLC模型系统中显著的且持久的细胞状态分化并抑制生长。

Journal of Thoracic Oncology
IF20.8
2025-08-290
PRE
Sambad Sharma; James Neef; Maulasri Bhatta; Sara Sinicropi-Yao; Joe DeBartolo; Henry Wilson; Zied Boudhraa; Mohamed El Ezzy; Betty Chan; Andrew McRiner; Mark Bittinger; Thomas G. Graeber; Laura Antipov; Katharine E. Yen; David S. Millan; Kimberly S. Straley
PGC-1α drives small cell neuroendocrine cancer progression toward an ASCL1-expressing subtype with increased mitochondrial capacity
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-11-260
OAAI
Varuzhanyan, Grigor; Chen, Chia-Chun; Freeland, Jack; He, Tian; Tran, Wendy; Song, Kai; Wang, Liang; Cheng, Donghui; Xu, Shili; Dibernardo, Gabriella A.; Esedebe, Favour N.; Bhatia, Vipul; Han, Mingqi; Abt, Evan R.; Park, Jung Wook; Memarzadeh, Sanaz; Shackelford, David B.; Lee, John K.; Graeber, Thomas G.; Shirihai, Orian S.; Witte, Owen N.
Integrated molecular and functional characterization of the intrinsic apoptotic machinery identifies therapeutic vulnerabilities in glioma

内在凋亡机制的综合分子和功能表征可确定神经胶质瘤的治疗脆弱性

NATURE COMMUNICATIONS
IF15.7
2024-11-210
OAAI
Fernandez, Elizabeth G.; Mai, Wilson X.; Song, Kai; Bayley, Nicholas A.; Kim, Jiyoon; Zhu, Henan; Pioso, Marissa; Young, Pauline; Andrasz, Cassidy L.; Cadet, Dimitri; Liau, Linda M.; Li, Gang; Yong, William H.; Rodriguez, Fausto J.; Dixon, Scott J.; Souers, Andrew J.; Li, Jingyi Jessica; Graeber, Thomas G.; Cloughesy, Timothy F.; Nathanson, David A.
A humanized monoclonal antibody targeting an ectonucleotidase rescues cardiac metabolism and heart function after myocardial infarction
CELL REPORTS
IF6.9
2024-11-010
OAAI
Li, Shen; Tao, Bo; Wan, Jijun; Montecino-Rodriguez, Enca; Wang, Ping; Ma, Feiyang; Sun, Baiming; Gu, Yiqian; Ramadoss, Sivakumar; Su, Lianjiu; Sun, Qihao; Ten Hoeve, Johanna; Stiles, Linsey; Collins, Jeffrey; Dam, R. Michael van; Tamboline, Mikayla; Taschereau, Richard; Shirihai, Orian; Kitchen, Douglas B.; Pellegrini, Matteo; Graeber, Thomas; Dorshkind, Kenneth; Xu, Shili; Deb, Arjun
MITF regulates IDH1, NNT, and a transcriptional program protecting melanoma from reactive oxygen species
SCIENTIFIC REPORTS
IF3.9
2024-09-143
OAAI
Roider, Elisabeth; Lakatos, Alexandra I. T.; McConnell, Alicia M.; Wang, Poguang; Mueller, Alina; Kawakami, Akinori; Tsoi, Jennifer; Szabolcs, Botond L.; Ascsillan, Anna A.; Suita, Yusuke; Igras, Vivien; Lo, Jennifer A.; Hsiao, Jennifer J.; Lapides, Rebecca; Pal, Dorottya M. P.; Lengyel, Anna S.; Navarini, Alexander; Okazaki, Arimichi; Iliopoulos, Othon; Nemeth, Istvan; Graeber, Thomas G.; Zon, Leonard; Giese, Roger W.; Kemeny, Lajos V.; Fisher, David E.

研究方向

暂未获取到该数据
A
Antoni Ribas
H 指数:158论文数:1,717被引数:16.2万
D
Daniel Braas
H 指数:38论文数:148被引数:1.0万
J
Jennifer Tsoi
H 指数:20论文数:106被引数:6,536
E
Evangelia Komisopoulou
H 指数:18论文数:41被引数:3,887
J
Johanna ten Hoeve
H 指数:23论文数:80被引数:3,687
L
Lídia Robert
H 指数:24论文数:106被引数:1.3万
B
Bjoern Titz
H 指数:37论文数:137被引数:5,648
H
Heather R. Christofk
H 指数:47论文数:205被引数:1.4万
N
Nicholas A. Graham
H 指数:25论文数:103被引数:3,110
R
Roger S. Lo
H 指数:61论文数:307被引数:3.3万