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Thomas G. Graeber

University of California

77H指数
457论文数
3.4W被引数
收录论文 141
发表时间
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l-Glutamine in combination with first-line gemcitabine and nab-paclitaxel in advanced pancreatic ductal adenocarcinoma: an open-label, single-arm, phase 1 GlutaPanc trial
errNature Cancer
IF28.5
err2026-08-31
err0
errOAAI
errJun Gong; Hayato Muranaka; So Yung Choi; Mourad Tighiouart; Shrikant Bhute; Ezinne R. Aja; Jonathan P. Jacobs; Aleksandr Stotland; Jennifer Van Eyk; Omer H. M. Elmadbouh; Mouad Edderkaoui; Sunao Tanaka; Hideki Furuya; Arsen Osipov; Jeremy Lorber; Sandrine Billet; Alexzandra Morris; Johanna ten Hoeve-Scott; Thomas Graeber; Stephen J. Pandol; Andrew Hendifar; Neil A. Bhowmick
err分享
err收藏
The liver regulates ectopic calcification in Abcc6- deficient models of pseudoxanthoma elasticum肝脏调节假性弹性纤维假黄瘤Abcc6缺陷模型的异位钙化
errJournal of Clinical Investigation
IF13.6
err2026-05-01
err0
PREAI
errWang, Yijie; Sun, Baiming; Ma, Feiyang; Tao, Bo; Gu, Yiqian; Zhou, Zhiqiang; Kim, Jason; Zhang, Linlin; Liu, Zhihao; ten Hoeve, Johanna; Stiles, Linsey; del Rio, Lucia Fernandez; Pan, Calvin; Shirihai, Orian; Xu, Shili; Graeber, Thomas G.; Sallam, Tamer; Pellegrini, Matteo; Lusis, Aldons J.; Deb, Arjun
err分享
err收藏
Author Correction: BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR–ABL1 kinase inhibition作者更正: BCL6使Ph急性淋巴细胞白血病细胞能够BCR-ABL1激酶抑制而存活
errNature
IF48.5
err2026-02-18
err0
PREAI
errCihangir Duy; Christian Hurtz; Seyedmehdi Shojaee; Leandro Cerchietti; Huimin Geng; Srividya Swaminathan; Lars Klemm; Soo-mi Kweon; Rahul Nahar; Melanie Braig; Eugene Park; Yong-mi Kim; Wolf-Karsten Hofmann; Sebastian Herzog; Hassan Jumaa; H. Phillip Koeffler; J. Jessica Yu; Nora Heisterkamp; Thomas G. Graeber; Hong Wu; B. Hilda Ye; Ari Melnick; Markus Müschen
err分享
err收藏
Discovery and Optimization of Orally Bioavailable Heterobifunctional Degraders of KAT2A/B for the Treatment of Cancer发现和优化具有口服生物利用度的异双功能KAT2A/B降解剂以用于癌症治疗
errJournal of Medicinal Chemistry
IF6.8
err2026-02-08
err0
PREAI
errJames Neef; Kimberly S. Straley; Chinmoy Mukherjee; Amol Tipnis; Suleman Riyajsaheb Maujan; Maulasri Bhatta; Sambad Sharma; Sara Sinicropi-Yao; Joe DeBartolo; Andrew J. McRiner; Betty Chan; Henry Wilson; Christina S. Lee; Zied Boudhraa; Mohamed El Ezzy; Mark Bittinger; Laura Jennings Antipov; Thomas G. Graeber; Katharine E. Yen; David S. Millan
err分享
err收藏
Bidirectional glutamine transport enables B-cell activation and transformation
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errSun, Ruifeng; Deb, Gauri; Kume, Kohei; Feng, Yanzhi; Scott, Johanna; Graeber, Thomas; Maschen, Markus
err分享
err收藏
GliomaPDOX - A direct brain-to-brain glioma xenograft library for drug discovery and developmentGliomaPDOX - 一个用于药物发现和开发的脑间胶质瘤异种移植库
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errFernandez, Elizabeth; Tse, Christopher; Salinas, Jennifer; Bayley, Nicholas; Ta, Lisa; Gosa, Laura; Zhu, Henan; Andrasz, Cassidy; Vigman, Michael; Sanvito, Francesco; Ellingson, Benjamin; Liau, Linda; Cloughesy, Timothy; Graeber, Thomas; Nathanson, David
err分享
err收藏
GBM NEURODEVELOPMENTAL LINEAGE PLASTICITY DRIVES RAPID ADAPTATION TO ONCOGENE TARGETED THERAPY胶质母细胞瘤神经发育谱系可塑性驱动对致癌基因靶向疗法的快速适应
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errCadet, Dimitri; Harris, Toby; Fazzari, Elisa; Andrasz, Cassidy; Bayley, Nicholas; Graeber, Thomas; Cloughesy, Timothy; Bhaduri, Aparna; Nathanson, David
err分享
err收藏
LIPID METABOLIC HETEROGENEITY ACROSS GLIOMA CELLULAR STATES REVEALS ENVIRONMENTAL DEPENDENCIES脂质代谢异质性跨越胶质瘤细胞状态揭示了环境依赖性
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errBayley, Nicholas; Minami, Jenna; Andrasz, Cassidy; Tse, Christopher; Salinas, Jennifer; Cadet, Dimitri; Bhaduri, Aparna; Cloughesy, Timothy; Graeber, Thomas; Nathanson, David
err分享
err收藏
Development of a leucine-rich repeat-containing protein 15-targeted radio-immunotheranostic approach to deplete pro-tumorigenic mechanisms and immunotherapy resistance靶向富含亮氨酸重复蛋白15的放射性免疫治疗诊断方法的开发，以耗竭促肿瘤机制和免疫治疗耐药性
errSignal Transduction and Targeted Therapy
IF52.7
err2025-09-30
err0
errOAAI
errClaire M. Storey; Mohamed Altai; Katharina Lückerath; Wahed Zedan; Henan Zhu; Lara Breuer; Marija Trajkovic-Arsic; Julie Park; Abbie Hasson; Jens Siveke; Diane Abou; Haley Marks; Enna Ulmert; Alexander Ridley; Marcella Safi; Urpo Lamminmäki; Constance Yuen; Susanne Geres; Liqun Mao; Michael Cheng; Sumit K. Subudhi; Bilal A. Siddiqui; Noah Federman; Johannes Czernin; Ken Herrmann; Laurent Bentolila; Xia Yang; Thomas G. Graeber; Robert Damoiseaux; Daniel Thorek; David Ulmert
err分享
err收藏
AUTX-703, A Novel and Potent KAT2A and KAT2B Proteint Degrader, Induces Profound and Persistent Cell State Differentiation and Inhibits Growth in SCLC Model SystemsAUTX-703，一种新型且高效的KAT2A和KAT2B蛋白质降解剂，可诱导SCLC模型系统中显著的且持久的细胞状态分化并抑制生长。
errJournal of Thoracic Oncology
IF20.8
err2025-08-29
err0
PREAI
errSambad Sharma; James Neef; Maulasri Bhatta; Sara Sinicropi-Yao; Joe DeBartolo; Henry Wilson; Zied Boudhraa; Mohamed El Ezzy; Betty Chan; Andrew McRiner; Mark Bittinger; Thomas G. Graeber; Laura Antipov; Katharine E. Yen; David S. Millan; Kimberly S. Straley
err分享
err收藏
Combined inhibition of de novo glutathione and nucleotide biosynthesis is synthetically lethal in glioblastoma联合抑制从头谷胱甘肽和核苷酸生物合成在胶质母细胞瘤中是合成致死的
errCELL REPORTS
IF6.9
err2025-05-01
err0
PREAI
errUdutha, Suresh; Taglang, Celine; Batsios, Georgios; Gillespie, Anne Marie; Tran, Meryssa; ten Hoeve, Johanna; Graeber, Thomas G.; Viswanath, Pavithra
err分享
err收藏
Complexity and Time
errJOURNAL OF THE EUROPEAN ECONOMIC ASSOCIATION
IF3.3
err2025-02-22
err0
PREAI
errEnke, Benjamin; Graeber, Thomas; Oprea, Ryan
err分享
err收藏
PGC-1α drives small cell neuroendocrine cancer progression toward an ASCL1-expressing subtype with increased mitochondrial capacity
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-11-26
err0
errOAAI
errVaruzhanyan, Grigor; Chen, Chia-Chun; Freeland, Jack; He, Tian; Tran, Wendy; Song, Kai; Wang, Liang; Cheng, Donghui; Xu, Shili; Dibernardo, Gabriella A.; Esedebe, Favour N.; Bhatia, Vipul; Han, Mingqi; Abt, Evan R.; Park, Jung Wook; Memarzadeh, Sanaz; Shackelford, David B.; Lee, John K.; Graeber, Thomas G.; Shirihai, Orian S.; Witte, Owen N.
err分享
err收藏
Integrated molecular and functional characterization of the intrinsic apoptotic machinery identifies therapeutic vulnerabilities in glioma内在凋亡机制的综合分子和功能表征可确定神经胶质瘤的治疗脆弱性
errNATURE COMMUNICATIONS
IF15.7
err2024-11-21
err0
errOAAI
errFernandez, Elizabeth G.; Mai, Wilson X.; Song, Kai; Bayley, Nicholas A.; Kim, Jiyoon; Zhu, Henan; Pioso, Marissa; Young, Pauline; Andrasz, Cassidy L.; Cadet, Dimitri; Liau, Linda M.; Li, Gang; Yong, William H.; Rodriguez, Fausto J.; Dixon, Scott J.; Souers, Andrew J.; Li, Jingyi Jessica; Graeber, Thomas G.; Cloughesy, Timothy F.; Nathanson, David A.
err分享
err收藏
LIPID METABOLIC HETEROGENEITY OF GLIOMA CELLULAR STATES REVEALS ENVIRONMENTAL DEPENDENCIES
errNEURO-ONCOLOGY
IF13.4
err2024-11-11
err0
PREAI
errBayley, Nicholas; Minami, Jenna; Tse, Christopher; Zhu, Henan; Salinas, Jennifer; Andrasz, Cassidy; Yan, Weihong; Cadet, Dimitri; Borujerdpur, Amir; Williams, Kevin; Bhaduri, Aparna; Bensinger, Steven; Liau, Linda; Cloughesy, Timothy; Graeber, Thomas; Nathanson, David
err分享
err收藏
BRAIN MICROENVIRONMENT-DEPENDENT NEURODEVELOPMENTAL LINEAGE PLASTICITY PROMOTES ADAPTATION TO ONCOGENE INHIBITION IN MALIGNANT GLIOMAS
errNEURO-ONCOLOGY
IF13.4
err2024-11-11
err0
PREAI
errCadet, Dimitri; Andrasz, Cassidy; Bayley, Nicholas; Fazzari, Elisa; Fernandez, Elizabeth; Okobi, Quincy; Graeber, Thomas; Bhaduri, Aparna; Cloughesy, Timothy; Nathanson, David
err分享
err收藏
LIPID METABOLIC PROGRAMS DEFINE GLIOMA STATE IDENTITY, PLASTICITY AND DEPENDENCIES
errNEURO-ONCOLOGY
IF13.4
err2024-11-11
err0
PREAI
errMinami, Jenna; Bayley, Nicholas; Tse, Christopher; Andrasz, Cassidy; Cadet, Dimitri; Salinas, Jennifer; Yan, Weihong; Borujerdpur, Amir; Liau, Linda; Cloughesy, Timothy; Williams, Kevin; Bensinger, Steven; Bhaduri, Aparna; Graeber, Thomas; Nathanson, David
err分享
err收藏
A humanized monoclonal antibody targeting an ectonucleotidase rescues cardiac metabolism and heart function after myocardial infarction
errCELL REPORTS
IF6.9
err2024-11-01
err0
errOAAI
errLi, Shen; Tao, Bo; Wan, Jijun; Montecino-Rodriguez, Enca; Wang, Ping; Ma, Feiyang; Sun, Baiming; Gu, Yiqian; Ramadoss, Sivakumar; Su, Lianjiu; Sun, Qihao; Ten Hoeve, Johanna; Stiles, Linsey; Collins, Jeffrey; Dam, R. Michael van; Tamboline, Mikayla; Taschereau, Richard; Shirihai, Orian; Kitchen, Douglas B.; Pellegrini, Matteo; Graeber, Thomas; Dorshkind, Kenneth; Xu, Shili; Deb, Arjun
err分享
err收藏
AUTX-703, a novel and potent KAT2A and KAT2B protein degrader, induces profound cell state changes and inhibits growth in Small Cell Lung Cancer (SCLC) model systems
errEUROPEAN JOURNAL OF CANCER
IF7.1
err2024-10-01
err0
PREAI
errSharma, S.; Neef, J.; Bhatta, M.; Sinicropi-Yao, S.; DeBartolo, J.; Wilson, H.; Boudhraa, Z.; El Ezzy, M.; Chan, B.; McRiner, A.; Bittinger, M.; Graeber, T.; Antipov, L.; Yen, K.; Millan, D.; Straley, K.
err分享
err收藏
MITF regulates IDH1, NNT, and a transcriptional program protecting melanoma from reactive oxygen species
errSCIENTIFIC REPORTS
IF3.9
err2024-09-14
err3
errOAAI
errRoider, Elisabeth; Lakatos, Alexandra I. T.; McConnell, Alicia M.; Wang, Poguang; Mueller, Alina; Kawakami, Akinori; Tsoi, Jennifer; Szabolcs, Botond L.; Ascsillan, Anna A.; Suita, Yusuke; Igras, Vivien; Lo, Jennifer A.; Hsiao, Jennifer J.; Lapides, Rebecca; Pal, Dorottya M. P.; Lengyel, Anna S.; Navarini, Alexander; Okazaki, Arimichi; Iliopoulos, Othon; Nemeth, Istvan; Graeber, Thomas G.; Zon, Leonard; Giese, Roger W.; Kemeny, Lajos V.; Fisher, David E.
err分享
err收藏

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