Fumio Arai - Publications, H-index & Citations

Fumio Arai

University of Osaka

43H指数

166论文数

1.2W被引数

收录论文 37

发表时间

Endosteal integrin-α8⁺ mesenchymal stem cells maintain haematopoietic stem cell function via extracellular matrix-mediated interactions 骨内整合素-α8阳性间充质干细胞通过细胞外基质介导的相互作用维持造血干细胞功能

Nature Communications

IF15.7

2026-07-06

OAAI

Ryosuke Yuta; Hisayuki Yao; Kentaro Hosokawa; Yuichiro Semba; Yuki Esaki; Shunichi Adachi; Ngan Thi Kim Nguyen; Ben D MacArthur; Fumio Arai

An Orally Available Derivative of a Specific CK2 Inhibitor for Regulating Circadian Rhythms and Acute Myeloid Leukemia 一种可口服的特异性CK2抑制剂的衍生物，用于调节昼夜节律和急性髓系白血病

Precision Chemistry

IF6.2

2026-01-01

OAAI

Oshima, Tsuyoshi; Setoyama, Daiki; Sugiyama, Akiko; Amaike, Kazuma; Yamanaka, Ikumi; Hosokawa, Kentaro; Nunomura, Kazuto; Kawamura, Kiyoshi; Srivastava, Ashutosh; Iida, Mui; Gotoh, Kazuhito; Lin, Bangzhong; Morita, Mikio; Ohmi, Masashi; Uchiumi, Takeshi; Arai, Fumio; Haruta, Junichi; Sudo, Masaki; Tama, Florence; Kunisaki, Yuya; Itami, Kenichiro; Hirota, Tsuyoshi

TP-0903 Suppresses Aurora A–PLK1 Signaling to Inhibit Proliferation of a Myelodysplastic Syndrome-Derived Cell Line TP-0903 通过抑制 Aurora A–PLK1 信号通路来抑制骨髓增生异常综合征衍生细胞系的增殖。

Cancer Science

IF4.3

2025-07-28

OAAI

Tomoko Kimura-Hyoda; Mikuri Ryu; Ryosuke Yuta; Saori Fukumoto; Kentaro Hosokawa; Hisayuki Yao; Yoko Yasuda; Koichi Miura; Kaoru Tohyama; Fumio Arai; Takeshi Uchiumi

Acute myeloid leukemia stem cells remodel the bone marrow niche via TGF-β-activated Alcam+ bone lining cells, creating a self-sustaining environment 急性髓系白血病干细胞通过TGF-β激活的Alcam+骨衬细胞重塑骨髓微环境，创造一个自维持的环境。

LEUKEMIA

IF13.4

2025-05-13

PREAI

Nguyen, Ngan Thi Kim; Yao, Hisayuki; Hosokawa, Kentaro; Esaki, Yuki; Yuta, Ryosuke; Adachi, Shunichi; Arai, Fumio

POT1a deficiency in mesenchymal niches perturbs B-lymphopoiesis

COMMUNICATIONS BIOLOGY

IF5.1

2023-09-29

OAAI

Nakashima, Kentaro; Kunisaki, Yuya; Hosokawa, Kentaro; Gotoh, Kazuhito; Yao, Hisayuki; Yuta, Ryosuke; Semba, Yuichiro; Nogami, Jumpei; Kikushige, Yoshikane; Stumpf, Patrick S.; MacArthur, Ben D.; Kang, Dongchon; Akashi, Koichi; Ohga, Shouichi; Arai, Fumio

MBTD1 preserves adult hematopoietic stem cell pool size and function

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-07-31

OAAI

Takubo, Keiyo; Htun, Phyo Wai; Ueda, Takeshi; Sera, Yasuyuki; Iwasaki, Masayuki; Koizumi, Miho; Shiroshita, Kohei; Kobayashi, Hiroshi; Haraguchi, Miho; Watanuki, Shintaro; Honda, Zen-ichiro; Yamasaki, Norimasa; Ishizu, Ayako Nakamura-; Arai, Fumio; Motoyama, Noboru; Hatta, Tomohisa; Natsume, Tohru; Suda, Toshio; Honda, Hiroaki

MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis MDS细胞通过细胞外囊泡损害msc的骨分化以抑制正常造血

CELL REPORTS

IF6.9

2022-05-01

OAAI

Hayashi, Yasutaka; Kawabata, Kimihito C.; Tanaka, Yosuke; Uehara, Yasufumi; Mabuchi, Yo; Murakami, Koichi; Nishiyama, Akira; Kiryu, Shigeru; Yoshioka, Yusuke; Ota, Yasunori; Sugiyama, Tatsuki; Mikami, Keiko; Tamura, Moe; Fukushima, Tsuyoshi; Asada, Shuhei; Takeda, Reina; Kunisaki, Yuya; Fukuyama, Tomofusa; Yokoyama, Kazuaki; Uchida, Tomoyuki; Hagihara, Masao; Ohno, Nobuhiro; Usuki, Kensuke; Tojo, Arinobu; Katayama, Yoshio; Goyama, Susumu; Arai, Fumio; Tamura, Tomohiko; Nagasawa, Takashi; Ochiya, Takahiro; Inoue, Daichi; Kitamura, Toshio

Transfer learning efficiently maps bone marrow cell types from mouse to human using single-cell RNA sequencing

COMMUNICATIONS BIOLOGY

IF5.1

2020-12-04

OAAI

Stumpf, Patrick S.; Du, Xin; Imanishi, Haruka; Kunisaki, Yuya; Semba, Yuichiro; Noble, Timothy; Smith, Rosanna C. G.; Rose-Zerili, Matthew; West, Jonathan J.; Oreffo, Richard O. C.; Farrahi, Katayoun; Niranjan, Mahesan; Akashi, Koichi; Arai, Fumio; MacArthur, Ben D.

Machine Learning of Hematopoietic Stem Cell Divisions from Paired Daughter Cell Expression Profiles Reveals Effects of Aging on Self-Renewal

CELL SYSTEMS

IF7.7

2020-12-01

OAAI

Arai, Fumio; Stumpf, Patrick S.; Ikushima, Yoshiko M.; Hosokawa, Kentaro; Roch, Aline; Lutolf, Matthias P.; Suda, Toshio; MacArthur, Ben D.

Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo

CELL REPORTS

IF6.9

2019-07-01

OAAI

Kobayashi, Hiroshi; Morikawa, Takayuki; Okinaga, Ayumi; Hamano, Fumie; Hashidate-Yoshida, Tomomi; Watanuki, Shintaro; Hishikawa, Daisuke; Shindou, Hideo; Arai, Fumio; Kabe, Yasuaki; Suematsu, Makoto; Shimizu, Takao; Takubo, Keiyo

Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis

NATURE COMMUNICATIONS

IF15.7

2019-03-06

OAAI

Kidoya, Hiroyasu; Muramatsu, Fumitaka; Shimamura, Teppei; Jia, Weizhen; Satoh, Takashi; Hayashi, Yumiko; Naito, Hisamichi; Kunisaki, Yuya; Arai, Fumio; Seki, Masahide; Suzuki, Yutaka; Osawa, Tsuyoshi; Akira, Shizuo; Takakura, Nobuyuki

Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth

SCIENCE ADVANCES

IF12.5

2019-01-04

OAAI

Oshima, Tsuyoshi; Niwa, Yoshimi; Kuwata, Keiko; Srivastava, Ashutosh; Hyoda, Tomoko; Tsuchiya, Yoshiki; Kumagai, Megumi; Tsuyuguchi, Masato; Tamaru, Teruya; Sugiyama, Akiko; Ono, Natsuko; Zolboot, Norjin; Aikawa, Yoshiki; Oishi, Shunsuke; Nonami, Atsushi; Arai, Fumio; Hagihara, Shinya; Yamaguchi, Junichiro; Tama, Florence; Kunisaki, Yuya; Yagita, Kazuhiro; Ikeda, Masaaki; Kinoshita, Takayoshi; Kay, Steve A.; Itami, Kenichiro; Hirota, Tsuyoshi

Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress

CELL STEM CELL

IF20.4

2018-05-01

OAAI

Tadokoro, Yuko; Hoshii, Takayuki; Yamazaki, Satoshi; Eto, Koji; Ema, Hideo; Kobayashi, Masahiko; Ueno, Masaya; Ohta, Kumiko; Arai, Yuriko; Hara, Eiji; Harada, Kenichi; Oshima, Masanobu; Oshima, Hiroko; Arai, Fumio; Yoshimura, Akihiko; Nakauchi, Hiromitsu; Hirao, Atsushi

The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age

NATURE COMMUNICATIONS

IF15.7

2017-10-06

OAAI

Hosokawa, Kentaro; MacArthur, Ben D.; Ikushima, Yoshiko Matsumoto; Toyama, Hirofumi; Masuhiro, Yoshikazu; Hanazawa, Shigemasa; Suda, Toshio; Arai, Fumio

Functional dissection of hematopoietic stem cell populations with a stemness-monitoring system based on NS-GFP transgene expression

SCIENTIFIC REPORTS

IF3.9

2017-09-12

OAAI

Ali, Mohamed A. E.; Fuse, Kyoko; Tadokoro, Yuko; Hoshii, Takayuki; Ueno, Masaya; Kobayashi, Masahiko; Nomura, Naho; Vu, Ha Thi; Peng, Hui; Hegazy, Ahmed M.; Masuko, Masayoshi; Sone, Hirohito; Arai, Fumio; Tajima, Atsushi; Hirao, Atsushi

Stem Cell Differentiation as a Non-Markov Stochastic Process

CELL SYSTEMS

IF7.7

2017-09-01

122

OAAI

Stumpf, Patrick S.; Smith, Rosanna C. G.; Lenz, Michael; Schuppert, Andreas; Mueller, Franz-Josef; Babtie, Ann; Chan, Thalia E.; Stumpf, Michael P. H.; Please, Colin P.; Howison, Sam D.; Arai, Fumio; MacArthur, Ben D.

Determining c-Myb Protein Levels Can Isolate Functional Hematopoietic Stem Cell Subtypes

Stem Cells

IF3.6

2015-01-22

PREAI

Sakamoto, Hiroshi; Takeda, Naoki; Arai, Fumio; Hosokawa, Kentaro; Garcia, Paloma; Suda, Toshio; Frampton, Jon; Ogawa, Minetaro

Regulation of cell cycle in hematopoietic stem cells by the niche 生态位对造血干细胞细胞周期的调控

CELL CYCLE

IF3.4

2014-10-27

OAAI

Hirao, A; Arai, F; Suda, T

A PML-PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

NATURE MEDICINE

IF50

2012-08-19

617

OAAI

Ito, Keisuke; Carracedo, Arkaitz; Weiss, Dror; Arai, Fumio; Ala, Ugo; Avigan, David E.; Schafer, Zachary T.; Evans, Ronald M.; Suda, Toshio; Lee, Chih-Hao; Pandolfi, Pier Paolo

Role of N-cadherin in the regulation of hematopoietic stem cells in the bone marrow niche N-钙粘蛋白在骨髓生态位造血干细胞调控中的作用

HEMATOPOIETIC STEM CELLS VIII

IF0

2012-08-17

PREAI

Arai, Fumio; Hosokawa, Kentaro; Toyama, Hirofumi; Matsumoto, Yoshiko; Suda, Toshio

研究方向