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收藏分享 收藏 Prodrug activation in malaria parasites mediated by an imported erythrocyte esterase, acylpeptide hydrolase (APEH)由导入的红细胞酯酶酰基肽水解酶（APEH）介导的疟原虫前药激活
Sundararamana, Sesh A.; Miller, Justin J.; Daleya, Ellora C.; O'Briena, Kelsey A.; Kasakc, Paulina; Danielsd, Abigail M.; Edwardse, Rachel L.; Heidelg, Kenneth M.; Bagueg, Darean A.; Wilsonh, Madeleine A.; Koelperh, Andrew J.; Kourtoglouh, Elexi C.; Whiteh, Alex D.; Augusth, Sloan A.; Appleh, Georgia A.; Rouambah, Regis W.; Durandh, Anthony J.; Estebh, John J.; Mulleri, Florian L.; Johnsonh, R. Jeremy; Hoopsh, Geoffrey C.; Dowdg, Cynthia S.; John, Audrey R. Odom 分享 收藏 Enolase inhibitors as therapeutic leads for Naegleria fowleri infectionMilanes, Jillian E.; Yan, Victoria C.; Pham, Cong-Dat; Muller, Florian; Kwain, Samuel; Rees, Kerrick C.; Dominy, Brian N.; Whitehead, Daniel C.; Millward, Steven W.; Bolejack, Madison; Shek, Roger; Tillery, Logan; Phan, Isabelle Q.; Staker, Bart; Moseman, E. Ashley; Zhang, Xiang; Ma, Xipeng; Jebet, Audriy; Yin, Xinmin; Morris, James C. 分享 收藏 分享 收藏 分享 收藏 Cook et al. An Optimized Bioassay for Screening Combined Anticoronaviral Compounds for Efficacy against Feline Infectious Peritonitis Virus with Pharmacokinetic Analyses of GS-441524, Remdesivir, and Molnupiravir in Cats. Viruses( vol 14, pg 2429, 2022)Cook, Sarah; Wittenburg, Luke; Yan, Victoria C.; Theil, Jacob H.; Castillo, Diego; Reagan, Krystle L.; Williams, Sonyia; Pham, Cong-Dat; Li, Chun; Muller, Florian L.; Murphy, Brian G. 分享 收藏 ATP1A1/BCL2L1 predicts the response of myelomonocytic and monocytic acute myeloid leukemia to cardiac glycosidesCerella, Claudia; Gajulapalli, Sruthi Reddy; Lorant, Anne; Gerard, Deborah; Muller, Florian; Lee, Yejin; Kim, Kyung Rok; Han, Byung Woo; Christov, Christo; Recher, Christian; Sarry, Jean-Emmanuel; Dicato, Mario; Diederich, Marc 分享 收藏 Enolase Inhibitors as Early Lead Therapeutics against Trypanosoma brucei烯醇化酶抑制剂作为布氏锥虫的早期先导治疗剂Roster, Colm P.; Lavigne, Danielle; Milanes, Jillian E.; Knight, Emily; Anderson, Heidi D.; Pizarro, Sabrina; Harding, Elijah M.; Morris, Meredith T.; Yan, Victoria C.; Pham, Cong-Dat; Muller, Florian; Kwain, Samuel; Rees, Kerrick C.; Dominy, Brian; Whitehead, Daniel C.; Uddin, Md Nasir; Millward, Steven W.; Morris, James C. 分享 收藏 分享 收藏 Marine Polyether Phycotoxin Palytoxin Induces Apoptotic Cell Death via Mcl-1 and Bcl-2 DownregulationKim, Jaemyun; Ji, Seungwon; Lee, Jin-Young; Lorquin, Jean; Orlikova-Boyer, Barbora; Cerella, Claudia; Mazumder, Aloran; Muller, Florian; Dicato, Mario; Detournay, Olivier; Diederich, Marc 分享 收藏 Sulfation is required for prostate cancer xenograft tumor formation but is dispensable for cell viability in vitroChen, Ko-Chien; Liu, Yonhong; Lin, Chenchu; Yen, Er-Yen Nick; Citron, Francesca; Ma, Xingdi; Lin, Tan; Lorenzi, Philip; Muller, Florian; DePinho, Ronald 分享 收藏 Prodrugs of a 1-hydroxy-2-oxopiperidin-3-yl phosphonate enolase inhibitor for the treatment of ENO1-deleted cancersYan, Victoria C.; Pham, Cong-Dat; Ballato, Elliot S.; Yang, Kristine L.; Khadka, Sunada; Barektain, Yasaman; Shrestha, Prakriti; Tran, Theresa; Poral, Anton H.; Washington, Mykia; Raghavan, Sudhir; Czako, Barbara; Pisaneschi, Federica; Lin, Yu-Hsi; Satani, Nikunj; Hammoudi, Naima; Ackroyd, Jeffrey J.; Georgiou, Dimitra K.; Millward, Steven W.; Muller, Florian L. 分享 收藏 分享 收藏 分享 收藏 An Optimized Bioassay for Screening Combined Anticoronaviral Compounds for Efficacy against Feline Infectious Peritonitis Virus with Pharmacokinetic Analyses of GS-441524, Remdesivir, and Molnupiravir in CatsCook, Sarah; Wittenburg, Luke; Yan, Victoria C.; Theil, Jacob H.; Castillo, Diego; Reagan, Krystle L.; Williams, Sonyia; Pham, Cong-Dat; Li, Chun; Muller, Florian L.; Murphy, Brian G. 分享 收藏 Prodrugs of a 1-Hydroxy-2-oxopiperidin-3-yl Phosphonate Enolase Inhibitor for the Treatment of ENO1-Deleted CancersYan, Victoria C.; Pham, Cong-Dat; Ballato, Elliot S.; Yang, Kristine L.; Arthur, Kenisha; Khadka, Sunada; Barekatain, Yasaman; Shrestha, Prakriti; Tran, Theresa; Poral, Anton H.; Washington, Mykia; Raghavan, Sudhir; Czako, Barbara; Pisaneschi, Federica; Lin, Yu-Hsi; Satani, Nikunj; Hammoudi, Naima; Ackroyd, Jeffrey J.; Georgiou, Dimitra K.; Millward, Steven W.; Muller, Florian L. 分享 收藏 Quantification of Phosphonate Drugs by 1H-31P HSQC Shows That Rats Are Better Models of Primate Drug Exposure than MiceBarekatain, Yasaman; Khadka, Sunada; Harris, Kristen; Delacerda, Jorge; Yan, Victoria C.; Chen, Ko-Chien; Pham, Cong-Dat; Uddin, Md. Nasir; Avritcher, Rony; Eisenberg, Eugene J.; Kalluri, Raghu; Millward, Steven W.; Muller, Florian L. 分享 收藏 Endothelial extracellular vesicles promote tumour growth by tumour-associated macrophage reprogramming内皮细胞外囊泡通过肿瘤相关巨噬细胞重编程促进肿瘤生长Njock, Makon-Sebastien; O'Grady, Tina; Nivelles, Olivier; Lion, Michelle; Jacques, Sophie; Cambier, Maureen; Herkenne, Stephanie; Muller, Florian; Christian, Aurelie; Remacle, Claire; Guiot, Julien; Rahmouni, Souad; Dequiedt, Franck; Struman, Ingrid 分享 收藏 Inhibition of the mitochondrial protein Opa1 curtails breast cancer growthZamberlan, Margherita; Boeckx, Amandine; Muller, Florian; Vinelli, Federica; Ek, Olivier; Vianello, Caterina; Coart, Emeline; Shibata, Keitaro; Christian, Aurelie; Grespi, Francesca; Giacomello, Marta; Struman, Ingrid; Scorrano, Luca; Herkenne, Stephanie 分享 收藏 
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