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Thomas Zillinger

aarhus university
H指数:27
被引数:5,220

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Deleterious variants in the autophagy-related gene RB1CC1/FIP200 impair immunity to SARS-CoV-2

自噬相关基因RB1CC1/FIP200的有害变异损害了对SARS-CoV-2的免疫力

Nature Communications
IF15.7
2025-11-270
OAAI
Lili Hu; Renee M. van der Sluis; Kennith Brian Castelino; Bao-Cun Zhang; Andreas Ronit; Thomas Zillinger; Marvin Werner; Sofie Eg Jørgensen; Anne Louise Hansen; Alice Pedersen; Ryo Narita; Line S. Reinert; Bettina Bundgaard; Christian K. Holm; Aurelie Cobat; Jean-Laurent Casanova; Fulvio Reggiori; Muriel Mari; Søren R. Paludan; Trine H. Mogensen
Genetically heterozygous - transcriptionally homozygous IRF7 deficiency underlies herpesvirus CNS infections in humans
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2025-10-290
PRE
Werner, Marvin; Wolff, Jonas Holst; Taft, Justin; Zillinger, Thomas; Hinke, Daniela M.; Barfod, Toke S.; de Keukeleere, Kerstin; Winzig, Franziska; Bundgaard, Bettina; Narita, Ryo; Skov, Thomas Wisbech; Jensen, Julie A.; Jorgensen, Sofie E.; Jorgensen, Charlotte S.; Skouboe, Morten K.; Lassauniere, Ria; de Boer, Joke H.; Jakobsen, Martin R.; Mikkelsen, Jacob G.; Bogunovic, Dusan; Paludan, Soren R.; van der Sluis, Renee M.; Mogensen, Trine H.
Immunoengineering of a Photocaged 5-triphosphate Oligoribonucleotide Ligand for Spatiotemporal Control of RIG-I Activation in Cancer

光笼封的5-三磷酸寡核糖核苷酸配体的免疫工程改造，用于癌症中RIG-I活化的时空控制

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
2025-04-210
PRE
Lewash, Sandra Anika; Mckenney, Vivien Rose; Wuebben, Christine; Ludwig, Janos; Hosni, Racha; Radzey, Dirk; Toma, Marieta I.; Bartok, Eva; Schlee, Martin; Zillinger, Thomas; Heckel, Alexander; Hartmann, Gunther
Chronic endoplasmic reticulum stress in myotonic dystrophy type 2 promotes autoimmunity via mitochondrial DNA release
NATURE COMMUNICATIONS
IF15.7
2024-02-204
OAAI
Roesing, Sarah; Ullrich, Fabian; Meisterfeld, Susann; Schmidt, Franziska; Mlitzko, Laura; Croon, Marijana; Nattrass, Ryan G.; Eberl, Nadia; Mahlberg, Julia; Schlee, Martin; Wieland, Anja; Simon, Philipp; Hilbig, Daniel; Reuner, Ulrike; Rapp, Alexander; Bremser, Julia; Mirtschink, Peter; Drukewitz, Stephan; Zillinger, Thomas; Beissert, Stefan; Paeschke, Katrin; Hartmann, Gunther; Trifunovic, Aleksandra; Bartok, Eva; Guenther, Claudia
A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA
NUCLEIC ACIDS RESEARCH
IF13.1
2023-10-132
OAAI
de Regt, Ann Kristin; Anand, Kanchan; Ciupka, Katrin; Bender, Felix; Gatterdam, Karl; Putschli, Bastian; Fusshoeller, David; Hilbig, Daniel; Kirchhoff, Alexander; Hunkler, Charlotte; Wolter, Steven; Gruenewald, Agathe; Wallerath, Christina; Schuberth-Wagner, Christine; Ludwig, Janos; Paeschke, Katrin; Bartok, Eva; Hagelueken, Gregor; Hartmann, Gunther; Zillinger, Thomas; Geyer, Matthias; Schlee, Martin
Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing (vol 219, e0220759, 2022)

单核细胞衍生的巨噬细胞通过cGAS/STING/IFN介导的核酸传感加重肺血管炎 (219卷，e0220759，2022)

JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2022-11-110
OAAI
Kessler, Nina; Viehmann, Susanne F.; Krollmann, Calvin; Mai, Karola; Kirschner, Katharina M.; Luksch, Hella; Kotagiri, Prasanti; Boehner, Alexander M. C.; Huugen, Dennis; de Oliveira Mann, Carina C.; Otten, Simon; Weiss, Stefanie A. I.; Zillinger, Thomas; Dobrikova, Kristiyana; Jenne, Dieter E.; Behrendt, Rayk; Ablasser, Andrea; Bartok, Eva; Hartmann, Gunther; Hopfner, Karl-Peter; Lyons, Paul A.; Boor, Peter; Roesen-Wolff, Angela; Teichmann, Lino L.; Heeringa, Peter; Kurts, Christian; Garbi, Natalio
Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2022-11-0816
OAAI
Schumann, Tina; Ramon, Santiago Costas; Schubert, Nadja; Mayo, Mohamad Aref; Hega, Melanie; Maser, Katharina Isabell; Ada, Servi-Remzi; Sydow, Lukas; Hajikazemi, Mona; Badstuebner, Markus; Mueller, Patrick; Ge, Yan; Shakeri, Farhad; Buness, Andreas; Rupf, Benjamin; Lienenklaus, Stefan; Utess, Barbara; Muhandes, Lina; Haase, Michael; Rupp, Luise; Schmitz, Marc; Gramberg, Thomas; Manel, Nicolas; Hartmann, Gunther; Zillinger, Thomas; Kato, Hiroki; Bauer, Stefan; Gerbaulet, Alexander; Paeschke, Katrin; Roers, Axel; Behrendt, Rayk
SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA
MOLECULAR CELL
IF16.6
2022-10-0123
OAAI
Maharana, Shovamayee; Kretschmer, Stefanie; Hunger, Susan; Yan, Xiao; Kuster, David; Traikov, Sofia; Zillinger, Thomas; Gentzel, Marc; Elangovan, Shobha; Dasgupta, Padmanava; Chappidi, Nagaraja; Lucas, Nadja; Maser, Katharina Isabell; Maatz, Henrike; Rapp, Alexander; Marchand, Virginie; Chang, Young-Tae; Motorin, Yuri; Hubner, Norbert; Hartmann, Gunther; Hyman, Anthony A.; Alberti, Simon; Lee-Kirsch, Min Ae
Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

单核细胞来源的巨噬细胞通过cGAS/STING/IFN介导的核酸传感加重肺血管炎

JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2022-08-2316
OAAI
Kessler, Nina; Viehmann, Susanne F.; Krollmann, Calvin; Mai, Karola; Kirschner, Katharina M.; Luksch, Hella; Kotagiri, Prasanti; Boehner, Alexander M. C.; Huugen, Dennis; Mann, Carina C. de Oliveira; Otten, Simon; Weiss, Stefanie A., I; Zillinger, Thomas; Dobrikova, Kristiyana; Jenne, Dieter E.; Behrendt, Rayk; Ablasser, Andrea; Bartok, Eva; Hartmann, Gunther; Hopfner, Karl-Peter; Lyons, Paul A.; Boor, Peter; Roesen-Wolff, Angela; Teichmann, Lino L.; Heeringa, Peter; Kurts, Christian; Garbi, Natalio
Retinoic Acid-Inducible Gene I Activation Inhibits Human Respiratory Syncytial Virus Replication in Mammalian Cells and in Mouse and Ferret Models of Infection

视黄酸诱导的基因I激活抑制哺乳动物细胞以及小鼠和雪貂感染模型中人呼吸道合胞病毒的复制

JOURNAL OF INFECTIOUS DISEASES
IF4.5
2022-07-217
OAAI
Schwab, Lara S. U.; Farrukee, Rubaiyea; Eleouet, Jean Francois; Rameix-Welti, Marie Anne; Londrigan, Sarah L.; Brooks, Andrew G.; Hurt, Aeron C.; Coch, Christoph; Zillinger, Thomas; Hartmann, Gunther; Reading, Patrick C.
Expression of a Functional Mx1 Protein Is Essential for the Ability of RIG-I Agonist Prophylaxis to Provide Potent and Long-Lasting Protection in a Mouse Model of Influenza A Virus Infection

功能性Mx1蛋白的表达对于rig-i激动剂预防在甲型流感病毒感染小鼠模型中提供有效和持久保护的能力至关重要

VIRUSES-BASEL
IF3.5
2022-07-154
OAAI
Schwab, Lara S. U.; Villalon-Letelier, Fernando; Tessema, Melkamu B.; Londrigan, Sarah L.; Brooks, Andrew G.; Hurt, Aeron; Coch, Christoph; Zillinger, Thomas; Hartmann, Gunther; Reading, Patrick C.
Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism
NATURE METABOLISM
IF20.8
2022-06-0274
OAAI
Chen, F.; Elgaher, W. A. M.; Winterhoff, M.; Buessow, K.; Waqas, F. H.; Graner, E.; Pires-Afonso, Y.; Perez, L. Casares; de la Vega, L.; Sahini, N.; Czichon, L.; Zobl, W.; Zillinger, T.; Shehata, M.; Pleschka, S.; Baehre, H.; Falk, C.; Michelucci, A.; Schuchardt, S.; Blankenfeldt, W.; Hirsch, A. K. H.; Pessler, F.
Deficiency in coatomer complex I causes aberrant activation of STING signalling
NATURE COMMUNICATIONS
IF15.7
2022-04-2849
OAAI
Steiner, Annemarie; Hrovat-Schaale, Katja; Prigione, Ignazia; Yu, Chien-Hsiung; Laohamonthonkul, Pawat; Harapas, Cassandra R.; Low, Ronnie Ren Jie; De Nardo, Dominic; Dagley, Laura F.; Mlodzianoski, Michael J.; Rogers, Kelly L.; Zillinger, Thomas; Hartmann, Gunther; Gantier, Michael P.; Gattorno, Marco; Geyer, Matthias; Volpi, Stefano; Davidson, Sophia; Masters, Seth L.
Recessive NLRC4-Autoinflammatory Disease Reveals an Ulcerative Colitis Locus
JOURNAL OF CLINICAL IMMUNOLOGY
IF5.7
2021-11-1625
OAAI
Steiner, Annemarie; Reygaerts, Thomas; Pontillo, Alessandra; Ceccherini, Isabella; Moecking, Jonas; Moghaddas, Fiona; Davidson, Sophia; Caroli, Francesco; Grossi, Alice; Morato Castro, Fabio Fernandes; Kalil, Jorge; Gohr, Florian N.; Schmidt, Florian, I; Bartok, Eva; Zillinger, Thomas; Hartmann, Gunther; Geyer, Matthias; Gattorno, Marco; Mendonca, Leonardo Oliveira; Masters, Seth L.
MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I
NATURE COMMUNICATIONS
IF15.7
2021-09-1737
OAAI
Braegelmann, Johannes; Lorenz, Carina; Borchmann, Sven; Nishii, Kazuya; Wegner, Julia; Meder, Lydia; Ostendorp, Jenny; Ast, David F.; Heimsoeth, Alena; Nakasuka, Takamasa; Hirabae, Atsuko; Okawa, Sachi; Dammert, Marcel A.; Plenker, Dennis; Klein, Sebastian; Lohneis, Philipp; Gu, Jianing; Godfrey, Laura K.; Forster, Jan; Trajkovic-Arsic, Marija; Zillinger, Thomas; Haarmann, Mareike; Quaas, Alexander; Lennartz, Stefanie; Schmiel, Marcel; D'Rozario, Joshua; Thomas, Emily S.; Li, Henry; Schmitt, Clemens A.; George, Julie; Thomas, Roman K.; von Karstedt, Silvia; Hartmann, Gunther; Buettner, Reinhard; Ullrich, Roland T.; Siveke, Jens T.; Ohashi, Kadoaki; Schlee, Martin; Sos, Martin L.

研究方向

暂未获取到该数据
G
Gunther Hartmann
H 指数:90论文数:428被引数:3.8万
E
Eva Bartok
H 指数:23论文数:84被引数:3,994
W
Winfried Barchet
H 指数:53论文数:138被引数:1.5万
M
Martin Schlee
H 指数:38论文数:99被引数:1.0万
C
Christoph Coch
H 指数:33论文数:89被引数:4,735
J
Julia Wegner
H 指数:6论文数:31被引数:412
R
Rayk Behrendt
H 指数:22论文数:130被引数:2,729
A
Andrëw G. Brööks
H 指数:76论文数:388被引数:1.8万
P
Patrick C. Reading
H 指数:58论文数:179被引数:1.0万
S
Sarah L. Londrigan
H 指数:26论文数:94被引数:1,834