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Immunoengineering of a Photocaged 5-triphosphate Oligoribonucleotide Ligand for Spatiotemporal Control of RIG-I Activation in Cancer 光笼封的5-三磷酸寡核糖核苷酸配体的免疫工程改造，用于癌症中RIG-I活化的时空控制 Lewash, Sandra Anika; Mckenney, Vivien Rose; Wuebben, Christine; Ludwig, Janos; Hosni, Racha; Radzey, Dirk; Toma, Marieta I.; Bartok, Eva; Schlee, Martin; Zillinger, Thomas; Heckel, Alexander; Hartmann, Gunther 分享 收藏
Isolation and characterization of extracellular vesicles from EGFR mutated lung cancer cells 从EGFR突变的肺癌细胞中分离和表征细胞外囊泡 Salih, Dian Jamel; Reiners, Katrin S.; Alfieri, Roberta; Salih, Ahmed Mohammed; Percario, Zulema Antonia; Di Stefano, Mariantonietta; Francesco, Sollitto; Affabris, Elisabetta; Hartmann, Gunther; Santantonio, Teresa 分享 收藏
RNA-binding proteins hnRNPM and ELAVL1 promote type-I interferon induction downstream of the nucleic acid sensors cGAS and RIG-I Kirchhoff, Alexander; Herzner, Anna-Maria; Urban, Christian; Piras, Antonio; Duester, Robert; Mahlberg, Julia; Gruenewald, Agathe; Schlee-Guimaraes, Thais M.; Ciupka, Katrin; Leka, Petro; Bootz, Robert J.; Wallerath, Christina; Hunkler, Charlotte; de Regt, Ann Kristin; Kuemmerer, Beate M.; Christensen, Maria Honholt; Schmidt, Florian, I; Lee-Kirsch, Min Ae; Guenther, Claudia; Kato, Hiroki; Bartok, Eva; Hartmann, Gunther; Geyer, Matthias; Pichlmair, Andreas; Schlee, Martin 分享 收藏
ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA Greiner-Tollersrud, Ole Kristian; Krausz, Mate; Boehler, Vincent; Polyzou, Aikaterini; Seidl, Maximilian; Spahiu, Ambra; Abdullah, Zeinab; Andryka-Cegielski, Katarzyna; Dominick, Felix Immunuel; Huebscher, Katrin; Goschin, Andreas; Smulski, Cristian R.; Trompouki, Eirini; Link, Regina; Ebersbach, Hilmar; Srinivas, Honnappa; Marchant, Martine; Sogkas, Georgios; Staab, Dieter; Vagbo, Cathrine; Guerini, Danilo; Baasch, Sebastian; Latz, Eicke; Hartmann, Gunther; Henneke, Philippe; Geiger, Roger; Peng, Xiao P.; Grimbacher, Bodo; Bartok, Eva; Alseth, Ingrun; Warncke, Max; Proietti, Michele 分享 收藏
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Chronic endoplasmic reticulum stress in myotonic dystrophy type 2 promotes autoimmunity via mitochondrial DNA release Roesing, Sarah; Ullrich, Fabian; Meisterfeld, Susann; Schmidt, Franziska; Mlitzko, Laura; Croon, Marijana; Nattrass, Ryan G.; Eberl, Nadia; Mahlberg, Julia; Schlee, Martin; Wieland, Anja; Simon, Philipp; Hilbig, Daniel; Reuner, Ulrike; Rapp, Alexander; Bremser, Julia; Mirtschink, Peter; Drukewitz, Stephan; Zillinger, Thomas; Beissert, Stefan; Paeschke, Katrin; Hartmann, Gunther; Trifunovic, Aleksandra; Bartok, Eva; Guenther, Claudia 分享 收藏
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A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA de Regt, Ann Kristin; Anand, Kanchan; Ciupka, Katrin; Bender, Felix; Gatterdam, Karl; Putschli, Bastian; Fusshoeller, David; Hilbig, Daniel; Kirchhoff, Alexander; Hunkler, Charlotte; Wolter, Steven; Gruenewald, Agathe; Wallerath, Christina; Schuberth-Wagner, Christine; Ludwig, Janos; Paeschke, Katrin; Bartok, Eva; Hagelueken, Gregor; Hartmann, Gunther; Zillinger, Thomas; Geyer, Matthias; Schlee, Martin 分享 收藏
Assessment of technical and clinical utility of a bead-based flow cytometry platform for multiparametric phenotyping of CNS-derived extracellular vesicles Brahmer, Alexandra; Geiss, Carsten; Lygeraki, Andriani; Neuberger, Elmo; Tzaridis, Theophilos; Nguyen, Tinh Thi; Luessi, Felix; Regnier-Vigouroux, Anne; Hartmann, Gunther; Simon, Perikles; Endres, Kristina; Bittner, Stefan; Reiners, Katrin S.; Kraemer-Albers, Eva-Maria 分享 收藏
Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy Heidegger, Simon; Stritzke, Florian; Dahl, Sarah; Dassler-Plenker, Juliane; Joachim, Laura; Buschmann, Dominik; Fan, Kaiji; Sauer, Carolin M.; Ludwig, Nils; Winter, Christof; Enssle, Stefan; Li, Suqi; Perl, Markus; Goergens, Andre; Haas, Tobias; Orberg, Erik Thiele; Goettert, Sascha; Woelfel, Catherine; Engleitner, Thomas; Cortes-Ciriano, Isidro; Rad, Roland; Herr, Wolfgang; Giebel, Bernd; Ruland, Jurgen; Bassermann, Florian; Coch, Christoph; Hartmann, Gunther; Poeck, Hendrik 分享 收藏
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Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode Litomosoides sigmodontis Scheunemann, Johanna F.; Risch, Frederic; Reichwald, Julia J.; Lenz, Benjamin; Neumann, Anna-Lena; Garbe, Stephan; Frohberger, Stefan J.; Koschel, Marianne; Ajendra, Jesuthas; Rothe, Maximilian; Latz, Eicke; Coch, Christoph; Hartmann, Gunther; Schumak, Beatrix; Hoerauf, Achim; Huebner, Marc P. 分享 收藏
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Loss of the Immunomodulatory Transcription Factor BATF2 in Humans Is Associated with a Neurological Phenotype Zsurka, Gabor; Appel, Maximilian L. T.; Nastaly, Maximilian; Hallmann, Kerstin; Hansen, Niels; Nass, Daniel; Baumgartner, Tobias; Surges, Rainer; Hartmann, Gunther; Bartok, Eva; Kunz, Wolfram S. 分享 收藏
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Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing (vol 219, e0220759, 2022) 单核细胞衍生的巨噬细胞通过cGAS/STING/IFN介导的核酸传感加重肺血管炎 (219卷，e0220759，2022) Kessler, Nina; Viehmann, Susanne F.; Krollmann, Calvin; Mai, Karola; Kirschner, Katharina M.; Luksch, Hella; Kotagiri, Prasanti; Boehner, Alexander M. C.; Huugen, Dennis; de Oliveira Mann, Carina C.; Otten, Simon; Weiss, Stefanie A. I.; Zillinger, Thomas; Dobrikova, Kristiyana; Jenne, Dieter E.; Behrendt, Rayk; Ablasser, Andrea; Bartok, Eva; Hartmann, Gunther; Hopfner, Karl-Peter; Lyons, Paul A.; Boor, Peter; Roesen-Wolff, Angela; Teichmann, Lino L.; Heeringa, Peter; Kurts, Christian; Garbi, Natalio 分享 收藏
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