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G

Guillermo Luxán

Goethe University Frankfurt
H指数:22
被引数:2,949

个人简介

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教育背景

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工作经历

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荣誉奖项

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Hematopoietic loss of KDM6A impairs cardiac recovery in heart failure via epigenetic reprogramming of myeloid cells

造血系统KDM6A缺失通过髓系细胞的表观遗传重编程损害心力衰竭的心脏恢复

Nature Cardiovascular Research
IF10.8
2026-11-030
OA
Emmanouil G. Solomonidis; Dennis Hecker; Mariana Shumliakivska; Julian Leberzammer; Ariane Fischer; Minh-Thuy Katschke; Melanie Bendel; Lara Korth; Bianca Schuhmacher; Laura Rumpf; Simone-Franziska Glaser; Katja Schmitz; Guillermo Luxán; Silke Frenz; Penelope Pennoyer; Annett Wilken-Schmitz; Tina Rasper; Sinan Zimmermann; Franziska Ganß; Evelyn Ullrich; David John; Stefan Guenther; Katalin Pálfi; Lisa M. Weiss; Matthias S. Leisegang; Ralf P. Brandes; Moritz von Scheidt; David M. Leistner; Andreas M. Zeiher; Wesley T. Abplanalp; Mario Looso; Marcel H. Schulz; Stefanie Dimmeler; Sebastian Cremer
STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

在HFpEF中，STAT3表达在心肌周细胞中降低，且其缺失会减少细胞黏附并诱导周细胞衰老。

FEBS LETTERS
IF3
2025-05-010
OAAI
Vanicek, Leah Rebecca; Fischer, Ariane; Jurado, Mariano Ruz; Tamiato, Anita; Procida-Kowalski, Tara; Wilhelm, Jochen; Hecker, Dennis; Merten, Maximilian; Escher, Felicitas; Kattih, Badder; Puntmann, Valentina; John, David; Schulz, Marcel H.; Nagel, Eike; Dimmeler, Stefanie; Luxan, Guillermo
Age-Dependent RGS5 Loss in Pericytes Induces Cardiac Dysfunction and Fibrosis

周细胞中年龄依赖性RGS5丢失诱导心功能障碍和纤维化

CIRCULATION RESEARCH
IF16.2
2024-05-103
OAAI
Tamiato, Anita; Tombor, Lukas S.; Fischer, Ariane; Muhly-Reinholz, Marion; Vanicek, Leah Rebecca; Togru, Buesra Nur; Neitz, Jessica; Glaser, Simone Franziska; Merten, Maximilian; Morales, David Rodriguez; Kwon, Jeonghyeon; Klatt, Stephan; Schumacher, Bianca; Guenther, Stefan; Abplanalp, Wesley T.; John, David; Fleming, Ingrid; Wettschureck, Nina; Dimmeler, Stefanie; Luxaen, Guillermo
DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts

DNMT3A克隆造血驱动突变通过成纤维细胞的旁分泌激活诱导心脏纤维化

NATURE COMMUNICATIONS
IF15.7
2024-01-197
OAAI
Shumliakivska, Mariana; Luxan, Guillermo; Hemmerling, Inga; Scheller, Marina; Li, Xue; Mueller-Tidow, Carsten; Schuhmacher, Bianca; Sun, Zhengwu; Dendorfer, Andreas; Debes, Alisa; Glaser, Simone-Franziska; Muhly-Reinholz, Marion; Kirschbaum, Klara; Hoffmann, Jedrzej; Nagel, Eike; Puntmann, Valentina O.; Cremer, Sebastian; Leuschner, Florian; Abplanalp, Wesley Tyler; John, David; Zeiher, Andreas M.; Dimmeler, Stefanie
Aging impairs the neurovascular interface in the heart

衰老会损害心脏中的神经血管界面

Science
IF45.8
2023-01-010
OAAI
Julian U. G. Wagner; Lukas Stefan Tombor; Pedro Felipe Malacarne; Lisa-Maria Kettenhausen; Josefine Panthel; Haris Kujundzic; Nivethitha Manickam; Katja Schmitz; Maria Cipca; Kathrin A. Stilz; Ariane Fischer; Marion Muhly-Reinholz; Wesley Tyler Abplanalp; David John; Sarajo Kumar Mohanta; Christian Weber; Andreas J. R. Habenicht; Giulia Buchmann; Stephan Angendohr; Ehsan Amin; Katharina Scherschel; Nikolaj Klöcker; Malte Kelm; Dominik Schüttler; Sebastian Clauß; Stefan Günther; Thomas Boettger; Thomas W Braun; Christian Bär; Minh Duc Pham; Jaya Krishnan; Susanne S. Hille; Oliver Josef Müller; Tarik M. Bozoglu; Christian Kupatt; Eleonora Nardini; Selma Osmanagic‐Myers; Christian G. Meyer; Andreas Michael Zeiher; Ralf Peter Brandes; Guillermo Luxán; Stefanie Dimmeler
The splicing-regulatory lncRNA NTRAS sustains vascular integrity
EMBO REPORTS
IF6.2
2022-05-084
OA
Fouani, Youssef; Kirchhof, Luisa; Stanicek, Laura; Luxan, Guillermo; Heumueller, Andreas W.; Knau, Andrea; Fischer, Ariane; Devraj, Kavi; John, David; Neumann, Philipp; Bindereif, Albrecht; Boon, Reinier A.; Liebner, Stefan; Wittig, Ilka; Mogler, Carolin; Karimova, Madina; Dimmeler, Stefanie; Jae, Nicolas
Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants

人内皮细胞对SARS-CoV-2变异体感染的易感性增加

BASIC RESEARCH IN CARDIOLOGY
IF8
2021-07-0541
OAAI
Wagner, Julian U. G.; Bojkova, Denisa; Shumliakivska, Mariana; Luxan, Guillermo; Nicin, Luka; Aslan, Galip S.; Milting, Hendrik; Kandler, Joshua D.; Dendorfer, Andreas; Heumueller, Andreas W.; Fleming, Ingrid; Bibli, Sofia-Iris; Jakobi, Tobias; Dieterich, Christoph; Zeiher, Andreas M.; Ciesek, Sandra; Cinatl, Jindrich; Dimmeler, Stefanie
Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction
NATURE COMMUNICATIONS
IF15.7
2021-01-29183
OAAI
Tombor, Lukas S.; John, David; Glaser, Simone F.; Luxan, Guillermo; Forte, Elvira; Furtado, Milena; Rosenthal, Nadia; Baumgarten, Nina; Schulz, Marcel H.; Wittig, Janina; Rogg, Eva-Maria; Manavski, Yosif; Fischer, Ariane; Muhly-Reinholz, Marion; Klee, Kathrin; Looso, Mario; Selignow, Carmen; Acker, Till; Bibli, Sofia-Iris; Fleming, Ingrid; Patrick, Ralph; Harvey, Richard P.; Abplanalp, Wesley T.; Dimmeler, Stefanie

研究方向

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S
Stefanie Dimmeler
H 指数:164论文数:931被引数:9.8万
J
José Luís de la Pompa
H 指数:58论文数:162被引数:2.1万
D
David John
H 指数:41论文数:179被引数:7,290
W
Wesley Abplanalp
H 指数:26论文数:113被引数:3,409
A
Ariane Fischer
H 指数:28论文数:84被引数:6,698
M
Mariana Shumliakivska
H 指数:10论文数:26被引数:816
A
Andreas M. Zeiher
H 指数:164论文数:1,004被引数:11.2万
G
Gaetano D’Amato
H 指数:18论文数:37被引数:3,136
S
Simone-Franziska Glaser
H 指数:16论文数:40被引数:1,438
M
Marion Muhly-Reinholz
H 指数:19论文数:56被引数:1,857