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D

David John

Goethe University Frankfurt
H指数:41
被引数:7,322

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荣誉奖项

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Hematopoietic loss of KDM6A impairs cardiac recovery in heart failure via epigenetic reprogramming of myeloid cells

造血系统KDM6A缺失通过髓系细胞的表观遗传重编程损害心力衰竭的心脏恢复

Nature Cardiovascular Research
IF10.8
2026-11-030
OA
Emmanouil G. Solomonidis; Dennis Hecker; Mariana Shumliakivska; Julian Leberzammer; Ariane Fischer; Minh-Thuy Katschke; Melanie Bendel; Lara Korth; Bianca Schuhmacher; Laura Rumpf; Simone-Franziska Glaser; Katja Schmitz; Guillermo Luxán; Silke Frenz; Penelope Pennoyer; Annett Wilken-Schmitz; Tina Rasper; Sinan Zimmermann; Franziska Ganß; Evelyn Ullrich; David John; Stefan Guenther; Katalin Pálfi; Lisa M. Weiss; Matthias S. Leisegang; Ralf P. Brandes; Moritz von Scheidt; David M. Leistner; Andreas M. Zeiher; Wesley T. Abplanalp; Mario Looso; Marcel H. Schulz; Stefanie Dimmeler; Sebastian Cremer
Age-associated loss of lymphatic vessels promotes cardiac inflammation

年龄相关的淋巴管丧失促进心脏炎症

Nature Cardiovascular Research
IF10.8
2026-09-150
OA
Julian U. G. Wagner; Hamza Gulshan; Ibrahim Sultan; Salli Antila; Laia-Canes Esteve; David Rodriguez Morales; Mariano Ruz Jurado; David John; Emmanouil G. Solomonidis; Katja Schmitz; Josefine Panthel; Haris Kujundzic; Susanne Hille; Oliver J. Müller; Christoph Kugler; Haider Sami; Manfred Ogris; Simone-Franziska Glaser; Wesley T. Abplanalp; Tara Procida-Kowalski; Marek Bartkuhn; Evelyn Ullrich; Marion Muhly-Reinholz; Sarmad Ahmad Khan; Tarik Bozoglu; Christian Kupatt; Florian Buettner; Jochen Pöling; Thomas Braun; Kari Alitalo; Stefanie Dimmeler
Clonal hematopoiesis activates procalcific pathways in macrophages and promotes aortic valve stenosis

克隆性造血激活巨噬细胞中的促钙化通路并促进主动脉瓣狭窄

Journal of Clinical Investigation
IF13.6
2026-01-023
OA
Abplanalp, Wesley T.; Raddatz, Michael A.; Schuhmacher, Bianca; Mas-Peiro, Silvia; Zuriaga, Maria A.; Matesanz, Nuria; Fuster, Jose J.; Pershad, Yash; Vlasschaert, Caitlyn; Silver, Alexander J.; Farber-Eger, Eric; Xu, Yaomin; Wells, Quinn S.; Shahidi, Delara; Fatima, Sameen; Yang, Xiao; Boruah, Adwitiya A. P.; Ware, Akshay; Merten, Maximilian; von Scheidt, Moritz; John, David; Shumliakivska, Mariana; Muhly-Reinholz, Marion; Vasa-Nicotera, Mariuca; Guenter, Stefan; Savona, Michael R.; Lindman, Brian R.; Dimmeler, Stefanie; Bick, Alexander G.; Zeiher, Andreas M.
Atherosclerosis licenses for an exceeding immune response in COVID-19 disease by interferon priming in circulating myeloid cells

动脉粥样硬化通过循环髓系细胞中的干扰素预激活，引发COVID-19疾病中过度的免疫反应

Cardiovascular Research
IF13.3
2026-01-011
PRE
Leberzammer, Julian; Abplanalp, Wesley Tyler; Grikscheit, Katharina; Solomonidis, Emmanouil G.; Glaser, Simone-Franziska; Schuhmacher, Bianca; Merten, Maximilian; Jeremijev, Gligorije; Wilken-Schmitz, Annett; Korth, Lara; John, David; Gunther, Stefan; Kuenne, Carsten; Looso, Mario; Valasarajan, Chanil; Benes, Vladimir; Jung, Ferris; Niehaus, Vivianne; Anton, Gabriele; Stellbrink, Christoph; Rommele, Christoph; Gopel, Siri; Pullamsetti, Soni Savai; Vehreschild, Janne; Vehreschild, Maria; Ciesek, Sandra; Leistner, David M.; Zeiher, Andreas M.; Dimmeler, Stefanie; Cremer, Sebastian
Endothelial ZBTB16: a molecular shield against cardiac aging

内皮ZBTB16：抵御心脏衰老的分子盾牌

European Heart Journal
IF35.6
2026-01-011
PRE
Stilz, Kathrin A.; Leonard, Vincent Elvin; Rodriguez Morales, David; Glaser, Simone-Franziska; Larcher, Veronica; Ruz Jurado, Mariano; Malacarne, Pedro Felipe; Manickam, Nivethitha; Tombor, Lukas S.; Abplanalp, Wesley T.; Panthel, Josefine; Kujundzic, Haris; Fischer, Ariane; Schmitz, Katja; Muller, Oliver J.; Hille, Susanne; Kupatt, Christian; Bozoglu, Tarik; Sami, Haider; Ogris, Manfred; Procida-Kowalski, Tara; Bartkuhn, Marek; John, David; Yekelchyk, Michail; Schmachtel, Tessa; Rieger, Michael; Pham, Minh-Duc; Krishnan, Jaya; Gunther, Stefan; Brandes, Ralf P.; Braun, Thomas; Zeiher, Andreas M.; Wagner, Julian U. G.; Dimmeler, Stefanie
Beneficial effects of vascular endothelial growth factor B gene transfer in the aged heart

血管内皮生长因子B基因转移在老年心脏中的有益作用

CARDIOVASCULAR RESEARCH
IF13.3
2025-03-210
PRE
Nivethitha Manickam; Ibrahim Sultan; Josefine Panthel; Haris Kujundzic; Ariane Fischer; Katja Schmitz; Mariano Ruz Jurado; David Rodriguez Morales; David John; Simone-Franziska Glaser; Kathrin A Stilz; Pedro Felipe Malacarne; Ralf Peter Brandes; Thomas Braun; Carolin Lerchenmüller; Fynn Betge; Wesley T Abplanalp; Kari Alitalo; Stefanie Dimmeler; Julian U G Wagner
Prevalently carried HLA allele associates with inflammation and poor prognosis in HF patients via co-stimulatory and MHC-II enhanceosome regulation

普遍携带的HLA等位基因通过共刺激和MHC-II增强子复合物的调控与心力衰竭患者的炎症和不良预后相关联。

CIRCULATION
IF38.6
2024-11-120
PRE
Abplanalp, Wesley; Merten, Maximilian; Cremer, Sebastian; Rasper, Tina; Mustafic, Emina; Jurado, Mariano Ruz; John, David; Puntmann, Valentina; Nagel, Eike; Krishnan, Jaya; Guzik, Tomasz; Siedlinski, Mateusz; Zeiher, Andreas; Dimmeler, Stefanie
Age-Dependent RGS5 Loss in Pericytes Induces Cardiac Dysfunction and Fibrosis

周细胞中年龄依赖性RGS5丢失诱导心功能障碍和纤维化

CIRCULATION RESEARCH
IF16.2
2024-05-103
OAAI
Tamiato, Anita; Tombor, Lukas S.; Fischer, Ariane; Muhly-Reinholz, Marion; Vanicek, Leah Rebecca; Togru, Buesra Nur; Neitz, Jessica; Glaser, Simone Franziska; Merten, Maximilian; Morales, David Rodriguez; Kwon, Jeonghyeon; Klatt, Stephan; Schumacher, Bianca; Guenther, Stefan; Abplanalp, Wesley T.; John, David; Fleming, Ingrid; Wettschureck, Nina; Dimmeler, Stefanie; Luxaen, Guillermo
DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts

DNMT3A克隆造血驱动突变通过成纤维细胞的旁分泌激活诱导心脏纤维化

NATURE COMMUNICATIONS
IF15.7
2024-01-197
OAAI
Shumliakivska, Mariana; Luxan, Guillermo; Hemmerling, Inga; Scheller, Marina; Li, Xue; Mueller-Tidow, Carsten; Schuhmacher, Bianca; Sun, Zhengwu; Dendorfer, Andreas; Debes, Alisa; Glaser, Simone-Franziska; Muhly-Reinholz, Marion; Kirschbaum, Klara; Hoffmann, Jedrzej; Nagel, Eike; Puntmann, Valentina O.; Cremer, Sebastian; Leuschner, Florian; Abplanalp, Wesley Tyler; John, David; Zeiher, Andreas M.; Dimmeler, Stefanie
Disrupted Binding of Cystathionine γ-Lyase to p53 Promotes Endothelial Senescence

胱硫醚 γ-裂解酶与p53的结合破坏促进内皮衰老

CIRCULATION RESEARCH
IF16.2
2023-10-275
PRE
Hu, Jiong; Leisegang, Matthias S.; Looso, Mario; Drekolia, Maria-Kyriaki; Wittig, Janina; Mettner, Janina; Karantanou, Christina; Kyselova, Anastasia; Dumbovic, Gabrjela; Li, Xiaoming; Li, Yuanyuan; Guenther, Stefan; John, David; Siragusa, Mauro; Zukunft, Sven; Oo, James A.; Wittig, Ilka; Hille, Susanne; Weigert, Andreas; Knapp, Stefan; Brandes, Ralf P.; Mueller, Oliver J.; Papapetropoulos, Andreas; Sigala, Fragiska; Dobreva, Gergana; Kojonazarov, Baktybek; Fleming, Ingrid; Bibli, Sofia-Iris
Single-nuclear transcriptome profiling identifies persistent fibroblast activation in hypertrophic and failing human hearts of patients with longstanding disease
CARDIOVASCULAR RESEARCH
IF13.3
2023-08-307
PRE
Kattih, Badder; Boeckling, Felicitas; Shumliakivska, Mariana; Tombor, Lukas; Rasper, Tina; Schmitz, Katja; Hoffmann, Jedrzej; Nicin, Luka; Abplanalp, Wesley T.; Carstens, Daniel C.; Arsalan, Mani; Emrich, Fabian; Holubec, Tomas; Walther, Thomas; Puntmann, Valentina O.; Nagel, Eike; John, David; Zeiher, Andreas M.; Dimmeler, Stefanie

研究方向

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S
Stefanie Dimmeler
H 指数:164论文数:931被引数:9.8万
W
Wesley Abplanalp
H 指数:26论文数:113被引数:3,440
A
Andreas M. Zeiher
H 指数:164论文数:1,004被引数:11.2万
S
Simone-Franziska Glaser
H 指数:16论文数:40被引数:1,451
L
Lukas Tombor
H 指数:14论文数:52被引数:1,457
S
Shizuka Uchida
H 指数:32论文数:185被引数:5,977
A
Ariane Fischer
H 指数:28论文数:84被引数:6,716
S
Sebastian Cremer
H 指数:19论文数:93被引数:2,134
M
Marion Muhly-Reinholz
H 指数:19论文数:56被引数:1,870
S
Stefan Günther
H 指数:44论文数:245被引数:7,532