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B

Brian G. Monks

university of massachusetts system
H指数:39
被引数:2.0万

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A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
NATURE MEDICINE
IF50
2015-02-162.1K
OAAI
Coll, Rebecca C.; Robertson, Avril A. B.; Chae, Jae Jin; Higgins, Sarah C.; Munoz-Planillo, Raul; Inserra, Marco C.; Vetter, Irina; Dungan, Lara S.; Monks, Brian G.; Stutz, Andrea; Croker, Daniel E.; Butler, Mark S.; Haneklaus, Moritz; Sutton, Caroline E.; Nunez, Gabriel; Latz, Eicke; Kastner, Daniel L.; Mills, Kingston H. G.; Masters, Seth L.; Schroder, Kate; Cooper, Matthew A.; O'Neill, Luke A. J.
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

衔接子ASC具有传播炎症的细胞外和 “朊病毒” 活性

NATURE IMMUNOLOGY
IF27.6
2014-06-22665
OAAI
Franklin, Bernardo S.; Bossaller, Lukas; De Nardo, Dominic; Ratter, Jacqueline M.; Stutz, Andrea; Engels, Gudrun; Brenker, Christoph; Nordhoff, Mark; Mirandola, Sandra R.; Al-Amoudi, Ashraf; Mangan, Matthew S.; Zimmer, Sebastian; Monks, Brian G.; Fricke, Martin; Schmidt, Reinhold E.; Espevik, Terje; Jones, Bernadette; Jarnicki, Andrew G.; Hansbro, Philip M.; Busto, Patricia; Marshak-Rothstein, Ann; Hornemann, Simone; Aguzzi, Adriano; Kastenmueller, Wolfgang; Latz, Eicke
RNA and β-Hemolysin of Group B Streptococcus Induce Interleukin-1β ( IL-1β) by Activating NLRP3 Inflammasomes in Mouse Macrophages*
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2014-05-0183
OAAI
Gupta, Rahul; Ghosh, Shubhendu; Monks, Brian; DeOliveira, Rosane B.; Tzeng, Te-Chen; Kalantari, Parisa; Nandy, Anubhab; Bhattacharjee, Bornali; Chan, Jennie; Ferreira, Fabianno; Rathinam, Vijay; Sharma, Shruti; Lien, Egil; Silverman, Neal; Fitzgerald, Katherine; Firon, Arnaud; Trieu-Cuot, Patrick; Henneke, Philipp; Golenbock, Douglas T.
Mouse, but not Human STING, Binds and Signals in Response to the Vascular Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid

小鼠而不是人类的STING会响应血管破坏剂5，6-二甲基黄嘌呤酮-4-乙酸而结合并发出信号

JOURNAL OF IMMUNOLOGY
IF3.4
2013-05-15416
OAAI
Conlon, Joseph; Burdette, Dara L.; Sharma, Shruti; Bhat, Numana; Thompson, Mikayla; Jiang, Zhaozhao; Rathinam, Vijay A. K.; Monks, Brian; Jin, Tengchuan; Xiao, T. Sam; Vogel, Stefanie N.; Vance, Russell E.; Fitzgerald, Katherine A.
Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

前沿: nf-κb激活模式识别和细胞因子受体通过调节NLRP3表达来许可NLRP3炎性体激活

JOURNAL OF IMMUNOLOGY
IF3.4
2009-07-152.6K
OAAI
Bauernfeind, Franz G.; Horvath, Gabor; Stutz, Andrea; Alnemri, Emad S.; MacDonald, Kelly; Speert, David; Fernandes-Alnemri, Teresa; Wu, Jianghong; Monks, Brian G.; Fitzgerald, Katherine A.; Hornung, Veit; Latz, Eicke

研究方向

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D
Douglas T. Golenbock
H 指数:127论文数:351被引数:7.4万
E
Eicke Latz
H 指数:128论文数:512被引数:10.1万
K
Katherine A. Fitzgerald
H 指数:136论文数:611被引数:9.2万
A
Alberto Visintin
H 指数:37论文数:74被引数:9,783
S
Sanjay Ram
H 指数:50论文数:236被引数:9,201
T
Terje Espevik
H 指数:0论文数:0被引数:15
P
Peter A. Rice
H 指数:56论文数:352被引数:1.0万
E
Egil Lien
H 指数:66论文数:175被引数:2.4万
A
Andrea Stutz
H 指数:14论文数:24被引数:1.3万
S
Sunita Gulati
H 指数:35论文数:155被引数:3,779