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J

John E. Dick

princess margaret hospital
H指数:107
被引数:6.5万

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FATP2-mediated lipid metabolism enhances chimeric antigen receptor T-cell therapy resistance in B-cell acute lymphoblastic leukemia

FATP2介导的脂质代谢增强了B细胞急性淋巴细胞白血病中嵌合抗原受体T细胞疗法的抗性

Leukemia
IF13.4
2026-06-300
OAAI
Clarissa Garcia; Kaylyn U. Lyons; Julian Grandvallet Contreras; Tian Liu; Alexis J. Donnelly; Amanda J. Novak; Amy Argabright; Colin Anderson; Abby Grier; Sabrina Smith; Joshua Michlin; Jesutomisin Olusoji; Railey G. Mikeska; Xin Zhou; Huimin Geng; Jeremy T. Rahkola; Hiten N. Patel; Jeffrey G. Jacot; Markus Müschen; Angelo D’Alessandro; John E. Dick; Ilaria Iacobucci; Charles G. Mullighan; Julie A. Reisz; Tzu Phang; M. Eric Kohler; Matthew T. Witkowski
Human haematopoietic stem cells remember inflammatory stress

人类造血干细胞能够记忆炎症应激

Nature
IF48.5
2026-05-270
OAAI
Andy G. X. Zeng; Murtaza S. Nagree; Niels Asger Jakobsen; Sayyam Shah; Angelica Varesi; Jasmine Ryu Won Kang; Alex Murison; Jin-Gyu Cheong; Sven Turkalj; Xuan Zhang; Felix A. Radtke; Tsega-Ab Abera; Isabel N. X. Lim; Liqing Jin; Joana Araújo; Alicia G. Aguilar-Navarro; Darrien Parris; Jessica McLeod; Hyerin Kim; Ho Seok Lee; Lin Zhang; Mason Boulanger; Elyssa Bader; Elias Gbeha; Christopher N. Parkhurst; Elvin Wagenblast; Eugenia Flores-Figueroa; Bo Wang; Gregory W. Schwartz; Leonard D. Shultz; Anna S. Nam; H. Leighton Grimes; Steven Z. Josefowicz; Philip Awadalla; Paresh Vyas; John E. Dick; Stephanie Z. Xie
Transposable elements shape stemness in normal and leukemic hematopoiesis

转座元件在正常和白血病造血中的形状

Nature Genetics
IF29
2026-05-040
OAAI
Giacomo Grillo; Bettina Nadorp; Aditi Qamra; Bryce Drylie; Amanda Mitchell; Christopher Arlidge; Ankita Nand; Naoya Takayama; Alex Murison; Seyed Ali Madani Tonekaboni; Komaldeep Kaur Kang; Andrea Arruda; Jean C. Y. Wang; Mark D. Minden; Özgen Deniz; Héléna Boutzen; John E. Dick; Mathieu Lupien
Glutaredoxin 2 is essential for AML survival through mitochondrial permeability transition pore regulation

谷氧还蛋白2通过线粒体通透性转换孔调节对AML生存至关重要

Blood
IF23.1
2025-11-180
OAAI
Tianyi Ling; Cristiana O’Brien; Jonathan R. St-Germain; Vincent Rondeau; Mary Shi; Jacob M. Berman; Adrianna Cepa; Paula Saez Raez; Mark Wunderlich; Katharine M. Carter; Cody Stillwell; Christina Sexton; Rachel Culp-Hill; Julie A. Reisz; Saeer A. Adeel; Andy G. X. Zeng; Suraj Bansal; Emily Tsao; He Tian Chen; John E Dick
Multipotent lineage potential in B cell acute lymphoblastic leukemia is associated with distinct cellular origins and clinical features

B细胞急性淋巴细胞白血病的多能谱系潜能与特定的细胞起源和临床特征相关。

Nature Cancer
IF28.5
2025-06-270
PRE
Ilaria Iacobucci; Andy G. X. Zeng; Qingsong Gao; Laura Garcia-Prat; Pradyumna Baviskar; Sayyam Shah; Alex Murison; Veronique Voisin; Michelle Chan-Seng-Yue; Cheng Cheng; Chunxu Qu; Colin Bailey; Matthew Lear; Matthew T. Witkowski; Xin Zhou; Airen Zaldivar Peraza; Karishma Gangwani; Anjali S. Advani; Selina M. Luger; Mark R. Litzow; Jacob M. Rowe; Elisabeth M. Paietta; Wendy Stock; John E. Dick; Charles G. Mullighan
The Exportin, CSE1L, Regulates Ribosome Biogenesis and Is a Selective Dependency in Childhood and Young Adult Acute Myeloid Leukemia

Exportin CSE1L 调节核糖体生物发生，并且是儿童及年轻成人急性髓系白血病的选择性依赖。

BLOOD
IF23.1
2024-11-050
PRE
Egan, Grace; Kumar, Amit; Voisin, Veronique; Hurren, Rose; Chegini, Ali; Ling, Dakai; Thomas, Geethu Emily; Yan, Youngran; Feng, Yue; Bansal, Suraj; Zeng, Andy G. X.; Arruda, Andrea; Dick, John Edgar; Bader, Gary D.; Minden, Mark D.; Schimmer, Aaron D.
Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging

突变干细胞在人类克隆造血中的选择性优势与对炎症和衰老的反应减弱有关

CELL STEM CELL
IF20.4
2024-08-016
OAAI
Jakobsen, Niels Asger; Turkalj, Sven; Zeng, Andy G. X.; Stoilova, Bilyana; Metzner, Marlen; Rahmig, Susann; Nagree, Murtaza S.; Shah, Sayyam; Moore, Rachel; Usukhbayar, Batchimeg; Salazar, Mirian Angulo; Gafencu, Grigore-Aristide; Kennedy, Alison; Newman, Simon; Kendrick, Benjamin J. L.; Taylor, Adrian H.; Afinowi-Luitz, Rasheed; Gundle, Roger; Watkins, Bridget; Wheway, Kim; Beazley, Debra; Murison, Alex; Aguilar-Navarro, Alicia G.; Flores-Figueroa, Eugenia; Dakin, Stephanie G.; Carr, Andrew J.; Nerlov, Claus; Dick, John E.; Xie, Stephanie Z.; Vyas, Paresh
Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance

急性髓性白血病的单细胞染色质可及性分析揭示了耐药后的异质性谱系组成

COMMUNICATIONS BIOLOGY
IF5.1
2023-07-216
OAAI
Fan, Huihui; Wang, Feng; Zeng, Andy; Murison, Alex; Tomczak, Katarzyna; Hao, Dapeng; Jelloul, Fatima Zahra; Wang, Bofei; Barrodia, Praveen; Liang, Shaoheng; Chen, Ken; Wang, Linghua; Zhao, Zhongming; Rai, Kunal; Jain, Abhinav K. K.; Dick, John; Daver, Naval; Futreal, Andy; Abbas, Hussein A. A.
Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia

异二聚体细胞因子受体的不同组装控制白血病的Stemness程序

CANCER DISCOVERY
IF33.3
2023-05-166
OAAI
Kan, Winnie L.; Dhagat, Urmi; Kaufmann, Kerstin B.; Hercus, Timothy R.; Nero, Tracy L.; Zeng, Andy G. X.; Toubia, John; Barry, Emma F.; Broughton, Sophie E.; Gomez, Guillermo A.; Benard, Brooks A.; Dottore, Mara; Shing, Karen S. Cheung Tung; Boutzen, Helena; Samaraweera, Saumya E.; Simpson, Kaylene J.; Jin, Liqing; Goodall, Gregory J.; Begley, C. Glenn; Thomas, Daniel; Ekert, Paul G.; Tvorogov, Denis; D'Andrea, Richard J.; Dick, John E.; Parker, Michael W.; Lopez, Angel F.
Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity
HAEMATOLOGICA
IF7.9
2023-04-0619
OAAI
O'Brien, Cristiana; Ling, Tianyi; Berman, Jacob M.; Culp-Hill, Rachel; Reisz, Julie A.; Rondeau, Vincent; Jahangiri, Soheil; St-Germain, Jonathan; Macwan, Vinitha; Astori, Audrey; Zeng, Andy; Hong, Jun Young; Li, Meng; Yang, Min; Jana, Sadhan; Gamboni, Fabia; Tsao, Emily; Liu, Weiyi; Dick, John E.; Lin, Hening; Melnick, Ari; Tikhonova, Anastasia; Arruda, Andrea; Minden, Mark D.; Raught, Brian; D'Alessandro, Angelo; Jones, Courtney L.
In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
BLOOD CANCER DISCOVERY
IF11.5
2023-02-098
OAAI
Vujovic, Ana; de Rooij, Laura; Chahi, Ava Keyvani; Chen, He Tian; Yee, Brian A.; Loganathan, Sampath K.; Liu, Lina; Chan, Derek C. H.; Tajik, Amanda; Tsao, Emily; Moreira, Steven; Joshi, Pratik; Xu, Joshua; Wong, Nicholas; Balde, Zaldy; Jahangiri, Soheil; Zandi, Sasan; Aigner, Stefan; Dick, John E.; Minden, Mark D.; Schramek, Daniel; Yeo, Gene W.; Hope, Kristin J.
KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition
LEUKEMIA
IF13.4
2023-01-319
OA
Boila, Liberalis Debraj; Ghosh, Subhadeep; Bandyopadhyay, Subham K.; Jin, Liqing; Murison, Alex; Zeng, Andy G. X.; Shaikh, Wasim; Bhowmik, Satyaki; Muddineni, Siva Sai Naga Anurag; Biswas, Mayukh; Sinha, Sayantani; Chatterjee, Shankha Subhra; Mbong, Nathan; Gan, Olga I.; Bose, Anwesha; Chakraborty, Sayan; Arruda, Andrea; Kennedy, James A.; Mitchell, Amanda; Lechman, Eric R.; Banerjee, Debasis; Milyavsky, Michael; Minden, Mark D.; Dick, John E.; Sengupta, Amitava
Clinical significance of clonal hematopoiesis in the setting of autologous stem cell transplantation for lymphoma
AMERICAN JOURNAL OF HEMATOLOGY
IF9.9
2022-09-2610
PRE
Lackraj, Tracy; Ben Barouch, Sharon; Medeiros, Jessie J. F.; Pedersen, Stephanie; Danesh, Arnavaz; Bakhtiari, Mehran; Hong, Michael; Tong, Kit; Joynt, Jesse; Arruda, Andrea; Minden, Mark D.; Kuruvilla, John; Bhella, Sita; Kukreti, Vishal; Crump, Michael; Prica, Anca; Chen, Christine; Deng, Yangqing; Xu, Wei; Pugh, Trevor J.; Keating, Armand; Dick, John E.; Abelson, Sagi; Kridel, Robert

研究方向

暂未获取到该数据
M
Mark D. Minden
H 指数:92论文数:1,259被引数:4.4万
O
Olga I. Gan
H 指数:31论文数:192被引数:6,411
A
Andy G.X. Zeng
H 指数:15论文数:185被引数:1,427
E
Eric R. Lechman
H 指数:31论文数:108被引数:5,543
L
Liqing Jin
H 指数:24论文数:175被引数:5,946
J
Jean Wang
H 指数:57论文数:311被引数:1.7万
V
Véronique Voisin
H 指数:35论文数:173被引数:7,353
S
Stephanie Z. Xie
H 指数:23论文数:123被引数:3,445
G
Gary D. Bader
H 指数:125论文数:702被引数:10.3万
E
Elisa Laurenti
H 指数:44论文数:162被引数:1.5万