未登录 Maplirpacept: a CD47 decoy receptor with minimal red blood cell binding and robust anti-tumor efficacy Maplirpacept: 一种具有最小红细胞结合和强大抗肿瘤功效的CD47诱饵受体 Krishnamoorthy, Mithunah; Seelige, Ruth; Brown, Christopher R.; Chau, Nancy; Viller, Natasja Nielsen; Johnson, Lisa D. S.; Linderoth, Emma; Wang, Jean C. Y.; Dillon, Christopher P.; Abayasiriwardana, Keith; Lees, Clare; Wong, Mark; Kaneda, Megan M.; Uger, Robert A.; Lin, Gloria H. Y. 分享 收藏
Zelenirstat Inhibits N-Myristoyltransferases to Disrupt Src Family Kinase Signaling and Oxidative Phosphorylation, Killing Acute Myeloid Leukemia Cells Gamma, Jay M.; Liu, Qiang; Beauchamp, Erwan; Iyer, Aishwarya; Yap, Megan C.; Zak, Zoulika; Ekstrom, Cassidy; Pain, Rony; Kostiuk, Morris A.; Mackey, John R.; Brandwein, Joseph; Wang, Jean C. Y.; Berthiaume, Luc G. 分享 收藏
Identification of leukemia stem cell subsets with distinct transcriptional, epigenetic and functional properties Boutzen, Helena; Murison, Alex; Oriecuia, Alexa; Bansal, Suraj; Arlidge, Christopher; Wang, Jean C. Y.; Lupien, Mathieu; Kaufmann, Kerstin B.; Dick, John E. 分享 收藏
Prospective validation of the BOADICEA multifactorial breast cancer risk prediction model in a large prospective cohort study BOADICEA多因素乳腺癌风险预测模型在一项大型前瞻性队列研究中的前瞻性验证 Yang, Xin; Eriksson, Mikael; Czene, Kamila; Lee, Andrew; Leslie, Goska; Lush, Michael; Wang, Jean; Dennis, Joe; Dorling, Leila; Carvalho, Sara; Mavaddat, Nasim; Simard, Jacques; Schmidt, Marjanka K.; Easton, Douglas F.; Hall, Per; Antoniou, Antonis C. 分享 收藏
A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia Zeng, Andy G. X.; Bansal, Suraj; Jin, Liqing; Mitchell, Amanda; Chen, Weihsu Claire; Abbas, Hussein A.; Chan-Seng-Yue, Michelle; Voisin, Veronique; van Galen, Peter; Tierens, Anne; Cheok, Meyling; Preudhomme, Claude; Dombret, Herve; Daver, Naval; Futreal, P. Andrew; Minden, Mark D.; Kennedy, James A.; Wang, Jean C. Y.; Dick, John E. 分享 收藏
A clinical laboratory-developed LSC17 stemness score assay for rapid risk assessment of patients with acute myeloid leukemia Ng, Stanley W. K.; Murphy, Tracy; King, Ian; Zhang, Tong; Mah, Michelle; Lu, Zhibin; Stickle, Natalie; Ibrahimova, Narmin; Arruda, Andrea; Mitchell, Amanda; Mai, Ming; He, Rong; Madala, Bindu Swapna; Viswanatha, David S.; Dick, John E.; Chan, Steven; Virtanen, Carl; Minden, Mark D.; Mercer, Timothy; Stockley, Tracy; Wang, Jean C. Y. 分享 收藏
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Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis Subedi, Amit; Liu, Qiang; Ayyathan, Dhanoop M.; Sharon, David; Cathelin, Severine; Hosseini, Mohsen; Xu, Changjiang; Voisin, Veronique; Bader, Gary D.; D'Alessandro, Angelo; Lechman, Eric R.; Dick, John E.; Minden, Mark D.; Wang, Jean C. Y.; Chan, Steven M. 分享 收藏
Sphingosine-1-Phosphate Receptor 3 Potentiates Inflammatory Programs in Normal and Leukemia Stem Cells to Promote Differentiation Xie, Stephanie Z.; Kaufmann, Kerstin B.; Wang, Weijia; Chan-Seng-Yue, Michelle; Gan, Olga, I; Laurenti, Elisa; Garcia-Prat, Laura; Takayanagi, Shin-Ichiro; Ng, Stanley W. K.; Xu, ChangJiang; Zeng, Andy G. X.; Jin, Liqing; McLeod, Jessica; Wagenblast, Elvin; Mitchell, Amanda; Kennedy, James A.; Liu, Qiang; Boutzen, Helena; Kleinau, Melissa; Jargstorf, Joseph; Holmes, Gareth; Zhang, Yang; Voisin, Veronique; Bader, Gary D.; Wang, Jean C. Y.; Hannun, Yusuf A.; Luberto, Chiara; Schroeder, Timm; Minden, Mark D.; Dick, John E. 分享 收藏
CD200 expression marks leukemia stem cells in human AML Ho, Jenny M.; Dobson, Stephanie M.; Voisin, Veronique; McLeod, Jessica; Kennedy, James A.; Mitchell, Amanda; Jin, Liqing; Eppert, Kolja; Bader, Gary; Minden, Mark D.; Dick, John E.; Wang, Jean C. Y. 分享 收藏
SIRPαFc treatment targets human acute myeloid leukemia stem cells Galkin, Oleksandr; McLeod, Jessica; Kennedy, James A.; Jin, Liqing; Mbong, Nathan; Wong, Mark; Uger, Robert A.; Minden, Mark D.; Danska, Jayne S.; Wang, Jean C. Y. 分享 收藏
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The stem cell-associated gene expression signature allows risk stratification in pediatric acute myeloid leukemia Duployez, Nicolas; Marceau-Renaut, Alice; Villenet, Celine; Petit, Arnaud; Rousseau, Alexandra; Ng, Stanley W. K.; Paquet, Agnes; Gonzales, Fanny; Barthelemy, Adeline; Lepretre, Frederic; Pottier, Nicolas; Nelken, Brigitte; Michel, Gerard; Baruchel, Andre; Bertrand, Yves; Leverger, Guy; Lapillonne, Helene; Figeac, Martin; Dick, John E.; Wang, Jean C. Y.; Preudhomme, Claude; Cheok, Meyling 分享 收藏
Comparative genomic analysis of young-onset and late-onset colorectal cancer Luo, Jingqin; Giannakis, Marios; Colditz, Graham; Wang, Jean; Chapman, William; Toriola, Adetunji T.; Mito, Yoshiko; Nishihara, Reiko; Nowak, Jonathan; Fuchs, Charles; Giovannucci, Edward; Chan, Andrew T.; Bass, Adam; Ogino, Shuji; Fields, Ryan; Cao, Yin 分享 收藏
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Association between insulin resistance and breast cancer risk: A Mendelian randomization analysis of data from 228,000 women of European descent Shu, Xiang; Wu, Lang; Khankari, Nikhil K.; Michailidou, Kyriaki; Bolla, Manjeet K.; Wang, Jean; Dennis, Joe; Shu, Xiao-ou; Simard, Jacques; Easton, Douglas F.; Zheng, Wei 分享 收藏
Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells Nieborowska-Skorska, Margaret; Sullivan, Katherine; Dasgupta, Yashodhara; Podszywalow-Bartnicka, Paulina; Hoser, Grazyna; Maifrede, Silvia; Martinez, Esteban; Di Marcantonio, Daniela; Bolton-Gillespie, Elisabeth; Cramer-Morales, Kimberly; Lee, Jaewong; Li, Min; Slupianek, Artur; Gritsyuk, Daniel; Cerny-Reiterer, Sabine; Seferynska, Ilona; Stoklosa, Tomasz; Bullinger, Lars; Zhao, Huaqing; Gorbunova, Vera; Piwocka, Katarzyna; Valent, Peter; Civin, Curt I.; Muschen, Markus; Dick, John E.; Wang, Jean C. Y.; Bhatia, Smita; Bhatia, Ravi; Eppert, Kolja; Minden, Mark D.; Sykes, Stephen M.; Skorski, Tomasz 分享 收藏
Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity Graceffa, Russell F.; Boezio, Alessandro A.; Able, Jessica; Altmann, Steven; Berry, Loren M.; Boezio, Christiane; Butler, John R.; Chu-Moyer, Margaret; Cooke, Melanie; DiMauro, Erin F.; Dineen, Thomas A.; Bojic, Elma Feric; Foti, Robert S.; Fremeau, Robert T., Jr.; Guzman-Perez, Angel; Gao, Hua; Gunaydin, Hakan; Huang, Hongbing; Huang, Liyue; Ilch, Christopher; Jarosh, Michael; Kornecook, Thomas; Kreiman, Charles R.; La, Daniel S.; Ligutti, Joseph; Milgram, Benjamin C.; Lin, Min-Hwa Jasmine; Marx, Isaac E.; Nguyen, Hanh N.; Peterson, Emily A.; Rescourio, Gwen; Roberts, John; Schenkel, Laurie; Shimanovich, Roman; Sparling, Brian A.; Stellwagen, John; Taborn, Kristin; Vaida, Karina R.; Wang, Jean; Yeoman, John; Yu, Violeta; Zhu, Dawn; Moyer, Bryan D.; Weiss, Matthew M. 分享 收藏
Sulfonamides as Selective Nav1.7 Inhibitors: Optimizing Potency and Pharmacokinetics to Enable in Vivo Target Engagement (vol 7, pg 1062, 2016) Marx, Isaac E.; Dineen, Thomas A.; Able, Jessica; Bode, Christiane; Bregman, Howard; Chu-Moyer, Margaret; DiMauro, Erin F.; Du, Bingfan; Foti, Robert S.; Fremeau, Robert T., Jr.; Gao, Hua; Gunaydin, Hakan; Hall, Brian E.; Huang, Liyue; Kornecook, Thomas; Kreiman, Charles R.; La, Daniel S.; Ligutti, Joseph; Lin, Min-Hwa Jasmine; Liu, Dong; McDermott, Jeff S.; Moyer, Bryan D.; Nguyen, Hanh N.; Peterson, Emily A.; Roberts, Jonathan T.; Rose, Paul; Wang, Jean; Youngblood, Beth D.; Yu, Violeta; Weiss, Matthew M. 分享 收藏
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