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J

Joseph Lehár

Novartis
H指数:41
被引数:3.2万

个人简介

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荣誉奖项

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Quantifying neurologic disease using biosensor measurements in-clinic and in free-living settings in multiple sclerosis

在多发性硬化症的临床和自由生活环境中使用生物传感器测量来量化神经系统疾病

NPJ DIGITAL MEDICINE
IF15.1
2019-12-1136
OAAI
Chitnis, Tanuja; Glanz, Bonnie I.; Gonzalez, Cindy; Healy, Brian C.; Saraceno, Taylor J.; Sattarnezhad, Neda; Diaz-Cruz, Camilo; Polgar-Turcsanyi, Mariann; Tummala, Subhash; Bakshi, Rohit; Bajaj, Vikram S.; Ben-Shimol, David; Bikhchandani, Nikhil; Blocker, Alexander W.; Burkart, Joshua; Cendrillon, Raphael; Cusack, Michael P.; Demiralp, Emre; Jooste, Sarel Kobus; Kharbouch, Alaa; Lee, Amy A.; Lehar, Joseph; Liu, Manway; Mahadevan, Swaminathan; Murphy, Mark; Norton, Linda C.; Parlikar, Tushar A.; Pathak, Anupam; Shoeb, Ali; Soderberg, Erin; Stephens, Philip; Stoertz, Aaron H.; Thng, Florence; Tumkur, Kashyap; Wang, Hongsheng; Rhodes, Jane; Rudick, Richard A.; Ransohoff, Richard M.; Phillips, Glenn A.; Bruzik, Effie; Marks, William J.; Weiner, Howard L.; Snyder, Thomas M.
Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf-/- mouse model
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2017-03-0649
OAAI
Chapeau, Emilie A.; Gembarska, Agnieszka; Durand, Eric Y.; Mandon, Emeline; Estadieu, Claire; Romanet, Vincent; Wiesmann, Marion; Tiedt, Ralph; Lehar, Joseph; de Weck, Antoine; Rad, Roland; Barys, Louise; Jeay, Sebastien; Ferretti, Stephane; Kauffmann, Audrey; Sutter, Esther; Grevot, Armelle; Moulin, Pierre; Murakami, Masato; Sellers, William R.; Hofmann, Francesco; Jensen, Michael Rugaard
High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response

使用患者来源的肿瘤异种移植物进行高通量筛选以预测临床试验药物反应

NATURE MEDICINE
IF50
2015-10-191.1K
PREAI
Gao, Hui; Korn, Joshua M.; Ferretti, Stephane; Monahan, John E.; Wang, Youzhen; Singh, Mallika; Zhang, Chao; Schnell, Christian; Yang, Guizhi; Zhang, Yun; Balbin, O. Alejandro; Barbe, Stephanie; Cai, Hongbo; Casey, Fergal; Chatterjee, Susmita; Chiang, Derek Y.; Chuai, Shannon; Cogan, Shawn M.; Collins, Scott D.; Dammassa, Ernesta; Ebel, Nicolas; Embry, Millicent; Green, John; Kauffmann, Audrey; Kowa, Colleen; Leary, Rebecca J.; Lehar, Joseph; Liang, Ying; Loo, Alice; Lorenzana, Edward; McDonald, E. Robert, III; McLaughlin, Margaret E.; Merkin, Jason; Meyer, Ronald; Naylor, Tara L.; Patawaran, Montesa; Reddy, Anupama; Roeelli, Claudia; Ruddy, David A.; Salangsang, Fernando; Santacroce, Francesca; Singh, Angad P.; Tang, Yan; Tinetto, Walter; Tobler, Sonja; Velazquez, Roberto; Venkatesan, Kavitha; Von Arx, Fabian; Wang, Hui Qin; Wang, Zongyao; Wiesmann, Marion; Wyss, Daniel; Xu, Fiona; Bitter, Hans; Atadja, Peter; Lees, Emma; Hofmann, Francesco; Li, En; Keen, Nicholas; Cozens, Robert; Jensen, Michael Rugaard; Pryer, Nancy K.; Williams, Juliet A.; Sellers, William R.
A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity

已批准药物和分子探针的筛选鉴定具有抗埃博拉病毒活性的治疗剂

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2015-06-03206
OAAI
Johansen, Lisa M.; DeWald, Lisa Evans; Shoemaker, Charles J.; Hoffstrom, Benjamin G.; Lear-Rooney, Calli M.; Stossel, Andrea; Nelson, Elizabeth; Delos, Sue E.; Simmons, James A.; Grenier, Jill M.; Pierce, Laura T.; Pajouhesh, Hassan; Lehar, Joseph; Hensley, Lisa E.; Glass, Pamela J.; White, Judith M.; Olinger, Gene G.
Characterization of the Novel and Specific PI3Kα Inhibitor NVP-BYL719 and Development of the Patient Stratification Strategy for Clinical Trials

新型特异性PI3Kα 抑制剂NVP-BYL719的特征和临床试验患者分层策略的发展

MOLECULAR CANCER THERAPEUTICS
IF5.5
2014-05-05416
OAAI
Fritsch, Christine; Huang, Alan; Chatenay-Rivauday, Christian; Schnell, Christian; Reddy, Anupama; Liu, Manway; Kauffmann, Audrey; Guthy, Daniel; Erdmann, Dirk; De Pover, Alain; Furet, Pascal; Gao, Hui; Ferretti, Stephane; Wang, Youzhen; Trappe, Joerg; Brachmann, Saskia M.; Maira, Sauveur-Michel; Wilson, Christopher; Boehm, Markus; Garcia-Echeverria, Carlos; Chene, Patrick; Wiesmann, Marion; Cozens, Robert; Lehar, Joseph; Schlegel, Robert; Caravatti, Giorgio; Hofmann, Francesco; Sellers, William R.
Evaluation of prediction of in vivo activity from in vitro combinations: Examples using a MEK1/2 inhibitor combined with docetaxel in NSCLC models.
MOLECULAR CANCER THERAPEUTICS
IF5.5
2013-11-013
PRE
Mcsheehy, Paul Martin J.; Cao, Alex; Caponigro, Giordi; Duhl, David; Firestone, Brant; Gesner, Tom; Guthy, Daniel; Holash, Jocelyn; King, Fred; Lehar, Joseph; Leroy, Christopher; Liu, Manway; Petruzzellil, Lilli; Porter, Dale; Menezes, Daniel; Reddy, Anupama; Roesel, Johannes; Schnell, Christian; Smith, Timothy; Stump, Mark; Wartmann, Markus; Wiesmann, Marion
Towards defining the genetic framework for clinical response to treatment with BYL719, a PI3Kalpha-specific inhibitor.
CANCER RESEARCH
IF16.6
2013-04-011
PRE
Rodon, Jordi; Juric, Dejan; Gonzalez-Angulo, Ana-Maria; Bendell, Johanna; Berlin, Jordan; Bootle, Douglas; Gravelin, Kathlene; Huang, Alan; Derti, Adnan; Lehar, Joseph; Wuerthner, Jens; Boehm, Markus; van Allen, Eliezer; Wagle, Nikhil; Garraway, Levi A.; Yelensky, Roman; Stephens, Philip J.; Miller, Vincent A.; Schlegel, Robert; Quadt, Cornelia; Baselga, Jose

研究方向

暂未获取到该数据
E
E. Falco
H 指数:58论文数:504被引数:1.6万
C
C. S. Kochanek
H 指数:90论文数:1,396被引数:3.4万
R
Robert Schlegel
H 指数:69论文数:391被引数:2.9万
W
William R. Sellers
H 指数:118论文数:816被引数:8.5万
B
B. A. McLeod
H 指数:33论文数:195被引数:4,967
H
Hans‐Walter Rix
H 指数:144论文数:970被引数:9.4万
G
Giordano Caponigro
H 指数:35论文数:358被引数:1.8万
C
Charles R. Keeton
H 指数:45论文数:212被引数:6,655
L
Levi A. Garraway
H 指数:147论文数:1,018被引数:14.8万
A
Alexis A. Borisy
H 指数:13论文数:35被引数:3,108