未登录 The synthetic TRPML1 agonist ML-SA1 mitigates intracellular lipid accumulation induced by antipsychotics in vitro by stimulating release of extracellular microvesicles 合成TRPML1激动剂ML-SA1通过刺激外泌小泡的释放,在体外减轻抗精神病药物诱导的细胞内脂质积累。 Chavarria-Cubel, Irene; Molina, Yessenia L.; Babiy, Bohdan; Lerma, Milagros; Martinez-Botas, Javier; de la Pena, Gema; Vallejo, Maria T.; Villanueva-Blanco, Tamara; Gomez-Coronado, Diego; Alcazar, Alberto; Lasuncion, Miguel A.; Pastor, Oscar; Busto, Rebeca 分享 收藏
Rottlerin Stimulates Exosome/Microvesicle Release Via the Increase of Ceramide Levels Mediated by Ampk in an In Vitro Model of Intracellular Lipid Accumulation Molina, Yessenia L.; Garcia-Seisdedos, David; Babiy, Bohdan; Lerma, Milagros; Martinez-Botas, Javier; Casarejos, Maria J.; Vallejo, Maria T.; Gomez-Coronado, Diego; Lasuncion, Miguel A.; Pastor, Oscar; Busto, Rebeca 分享 收藏
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Hormone-sensitive lipase deficiency affects the expression of SR-BI, LDLr, and ABCA1 receptors/transporters involved in cellular cholesterol uptake and efflux and disturbs fertility in mouse testis 激素敏感性脂肪酶缺乏症会影响参与细胞胆固醇摄取和流出的sr-bi,LDLr和ABCA1受体/转运蛋白的表达,并干扰小鼠睾丸的生育能力 Emilia Casado, Maria; Huerta, Lydia; Marcos-Diaz, Ana; Isabel Ortiz, Ana; Kraemer, Fredric B.; Angel Lasuncion, Miguel; Busto, Rebeca; Martin-Hidalgo, Antonia 分享 收藏
MMAB promotes negative feedback control of cholesterol homeostasis Goedeke, Leigh; Canfran-Duque, Alberto; Rotllan, Noemi; Chaube, Balkrishna; Thompson, Bonne M.; Lee, Richard G.; Cline, Gary W.; McDonald, Jeffrey G.; Shulman, Gerald, I; Lasuncion, Miguel A.; Suarez, Yajaira; Fernandez-Hernando, Carlos 分享 收藏
Selective estrogen receptor modulators (SERMs) affect cholesterol homeostasis through the master regulators SREBP and LXR Fernandez-Suarez, Maria E.; Daimiel, Lidia; Villa-Turegano, Gemma; Vazquez Pavon, Maria; Busto, Rebeca; Escola-Gil, Joan C.; Platt, Frances M.; Lasuncion, Miguel A.; Martinez-Botas, Javier; Gomez-Coronado, Diego 分享 收藏
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Dietary squalene modifies plasma lipoproteins and hepatic cholesterol metabolism in rabbits Martinez-Beamonte, Roberto; Sanchez-Marco, Javier; Felices, Maria J.; Barranquero, Cristina; Gascon, Sonia; Arnal, Carmen; Burillo, Juan C.; Lasheras, Roberto; Busto, Rebeca; Lasuncion, Miguel A.; Rodriguez-Yoldi, Maria Jesus; Osada, Jesus 分享 收藏
Hepatic Synaptotagmin 1 is involved in the remodelling of liver plasma-membrane lipid composition and gene expression in male Apoe-deficient mice consuming a Western diet Sancho-Knapik, Sara; Pastor, Oscar; Barranquero, Cristina; Herrera Marcos, Luis, V; Guillen, Natalia; Arnal, Carmen; Gascon, Sonia; Navarro, Maria A.; Rodriguez-Yoldi, Maria J.; Busto, Rebeca; Lasuncion, Miguel A.; Osada, Jesus 分享 收藏
Changes in Soluble TWEAK Concentrations, but Not Those in Amyloid-β(1-40), Are Associated with a Decrease in Carotid Intima-Media Thickness after Bariatric Surgery in Obese Women Gomez-Martin, Jesus M.; Aracil, Enrique; Insenser, Maria; de la Pena, Gema; Lasuncion, Miguel A.; Galindo, Julio; Escobar-Morreale, Hector F.; Balsa, Jose A.; Botella-Carretero, Jose, I 分享 收藏
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Caveolin-1 Regulates Atherogenesis by Attenuating Low-Density Lipoprotein Transcytosis and Vascular Inflammation Independently of Endothelial Nitric Oxide Synthase Activation Ramirez, Cristina M.; Zhang, Xinbo; Bandyopadhyay, Chirosree; Rotllan, Noemi; Sugiyama, Michael G.; Aryal, Binod; Liu, Xinran; He, Shun; Kraehling, Jan R.; Ulrich, Victoria; Lin, Chin Sheng; Velazquez, Heino; Lasuncion, Miguel A.; Li, Guangxin; Suarez, Yajaira; Tellides, George; Swirski, Filip K.; Lee, Warren L.; Schwartz, Martin A.; Sessa, William C.; Fernandez-Hernando, Carlos 分享 收藏
Postprandial Circulating miRNAs in Response to a Dietary Fat Challenge Mantilla-Escalante, Diana C.; Lopez de las Hazas, Maria-Carmen; Gil-Zamorano, Judit; Del Pozo-Acebo, Lorena; Carmen Crespo, M.; Martin-Hernandez, Roberto; del Saz, Andrea; Tome-Carneiro, Joao; Cardona, Fernando; Cornejo-Pareja, Isabel; Garcia-Ruiz, Almudena; Briand, Olivier; Lasuncion, Miguel A.; Visioli, Francesco; Davalos, Alberto 分享 收藏
A new variant (c.1A > G) in LDLRAP1 causing autosomal recessive hypercholesterolemia: Characterization of the defect and response to PCSK9 inhibition Rodriguez-Jimenez, Carmen; Gomez-Coronado, Diego; Frias Vargas, Manuel; Cerrato, Francisca; Lahoz, Carlos; Saban-Ruiz, Jose; Gonzalez-Nieto, Daniel; Lasuncion, Miguel A.; Mostaza, Jose M.; Rodriguez-Novoa, Sonia 分享 收藏
A comprehensive evaluation of omega-3 fatty acid supplementation in cystic fibrosis patients using lipidomics Pastor, Oscar; Guzman-Lafuente, Paula; Serna, Jorge; Munoz-Hernandez, Marta; Lopez Neyra, Alejandro; Garcia-Rozas, Patricia; Garcia-Seisdedos, David; Alcazar, Alberto; Lasuncion, Miguel A.; Busto, Rebeca; Lamas Ferreiro, Adelaida 分享 收藏
Endothelial NOD1 directs myeloid cell recruitment in atherosclerosis through VCAM-1 Gonzalez-Ramos, Silvia; Paz-Garcia, Marta; Rius, Cristina; del Monte-Monge, Alberto; Rodriguez, Cristina; Fernandez-Garcia, Victoria; Andres, Vicente; Martinez-Gonzalez, Jose; Lasuncion, Miguel A.; Martin-Sanz, Paloma; Soehnlein, Oliver; Bosca, Lisardo 分享 收藏
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Ellagic acid protects from myelin-associated sphingolipid loss in experimental autoimmune encephalomyelitis Busto, Rebeca; Serna, Jorge; Perianes-Cachero, Aranzazu; Quintana-Portillo, Rocio; Garcia-Seisdedos, David; Canfran-Duque, Alberto; Paino, Carlos L.; Lerma, Milagros; Casado, Maria E.; Martin-Hidalgo, Antonia; Arilla-Ferreiro, Eduardo; Lasuncion, Miguel A.; Pastor, Oscar 分享 收藏
Beneficial changes on plasma apolipoproteins A and B, high density lipoproteins and oxidized low density lipoproteins in obese women after bariatric surgery: comparison between gastric bypass and sleeve gastrectomy Gomez-Martin, J. M.; Balsa, J. A.; Aracil, E.; Cuadrado-Ayuso, M.; Rosillo, M.; De la Pena, G.; Lasuncion, M. A.; Escobar-Morreale, H. F.; Botella-Carretero, J. I. 分享 收藏
Lanosterol Modulates TLR4-Mediated Innate Immune Responses in Macrophages Araldi, Elisa; Fernandez-Fuertes, Marta; Canfran-Duque, Alberto; Tang, Wenwen; Cline, Gary W.; Madrigal-Matute, Julio; Pober, Jordan S.; Lasuncion, Miguel A.; Wu, Dianqing; Fernandez-Hernando, Carlos; Suarez, Yajaira 分享 收藏