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Seladelpar in patients with primary biliary cholangitis and compensated cirrhosis: Efficacy and safety from RESPONSE and ASSURE studies 塞拉德尔帕(Seladelpar)在原发性胆汁性胆管炎合并代偿期肝硬化患者中的疗效与安全性:来自RESPONSE和ASSURE研究的数据 Gordon, Stuart C.; Villamil, Alejandra; Jacobson, Ira M.; Lawitz, Eric J.; Younes, Ziad; Silveira, Marina G.; Bowlus, Christopher L.; Drenth, Joost P. H.; Vierling, John M.; Morgera, Ulrike; Vasura, Adam; Dalekos, George; Galli, Andrea; Rabinovitz, Mordechai; Heo, Jeong; Nevens, Frederik; Levy, Cynthia; Zhou, Yan; Carroll, Susheela; Crittenden, Daria B. 分享 收藏
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Long-Term Hepatic and Extrahepatic Outcomes of Chronic Hepatitis C Patients After Sofosbuvir-Based Treatment (LONGHEAD Study) 索磷布韦为基础治疗慢性丙型肝炎患者后的长期肝脏及肝外结局(LONGHEAD研究) Huang, Chung-Feng; Heo, Jeong; Chien, Rong-Nan; Baek, Yang-Hyun; Kao, Jia-Horng; Kim, Ju-Hyun; Chang, Ting-Tsung; Byun, Kwan-Soo; Chen, Jyh-Jou; Jeong, Sook-Hyang; Hu, Tsung-Hui; Kim, Young-Seok; Peng, Cheng-Yuan; Tak, Won-Young; Wang, Horng-Yuan; Yoon, Seung-Kew; Sheen, I. -Shyan; Hsu, Yu-Chun; Yim, Hyung-Joon; Tsai, Pei-Chien; Yeh, Ming-Lun; Ahn, Sang-Hoon; Dai, Chia-Yen; Paik, Seung-Woon; Huang, Jee-Fu; Kim, Yoon-Jun; Chuang, Wan-Long; Yu, Ming-Lung 分享 收藏
Phase Ib/IIa randomized study of heterologous ChAdOx1HBV/MVA-HBV therapeutic vaccination (VTP-300) as monotherapy and combined with low-dose nivolumab in virally-suppressed patients with CHB Tak, Won Young; Chuang, Wan-Lobg; Chen, Chi-Yi; Tseng, Kuo-Chih; Lim, Young-Suk; Lo, Gin-Ho; Heo, Jeong; Agarwal, Kaushik; Bussey, Louise; Teoh, Sui Lynn; Tria, A.; Brown, Anthony; Anderson, Katie; Vardeu, Antonella; O'Brien, Susanne; Kopycinski, Jakub; Kolenovska, Radka; Barnes, Ellie; Evans, Thomas 分享 收藏
Impact of baseline tumour burden on outcomes in EMERALD-1: A phase III study of durvalumab (D) ± bevacizumab (B) with transarterial chemoembolisation (TACE) in embolisation-eligible unresectable hepatocellular carcinoma (uHCC) EMERALD-1研究中基线肿瘤负荷对结局的影响:一项关于度伐利尤单抗(D)±贝伐珠单抗(B)联合经动脉化疗栓塞(TACE)在栓塞适应症的不可切除肝细胞癌(uHCC)中的III期研究 Kudo, M.; Lencioni, R.; Erinjeri, J.; Chan, S. L.; Qin, S.; Ren, Z.; Arai, Y.; Heo, J.; Breder, V. V.; Bouattour, M.; Dayyani, F.; Yoon, J-H.; Chiu, C-F.; Suttichaimongkol, T.; Decaens, T.; Griffin, R.; Morgan, C.; Ali, S. K.; Balaji, K.; Sangro, B. 分享 收藏
VIR-2218 (elebsiran) plus pegylated interferon-alfa-2a in participants with chronic hepatitis B virus infection: a phase 2 study Yuen, Man-Fung; Lim, Young-Suk; Yoon, Ki Tae; Lim, Tien-Huey; Heo, Jeong; Tangkijvanich, Pisit; Tak, Won Young; Thanawala, Vaidehi; Cloutier, Daniel; Mao, Shenghua; Arizpe, Andre; Cathcart, Andrea L.; Gupta, Sneha, V; Hwang, Carey; Gane, Edward 分享 收藏
Efficacy and Safety of Seladelpar in Patients With Primary Biliary Cholangitis and Compensated Liver Cirrhosis in the Open-Label, Long-Term ASSURE Safety Study: Interim Results Gordon, Stuart C.; Jacobson, Ira; Younes, Ziad H.; Silveira, Marina; Drenth, Joost; Morgera, Ulrike; Dalekos, George; Heo, Jeong; Yang, Ke; Heusner, Carrie; Crittenden, Daria B.; Mcwherter, Charles A. 分享 收藏
Long-Term Efficacy and Safety of Open-Label Seladelpar Treatment in Patients With Primary Biliary Cholangitis: Interim Results for 2 Years From the ASSURE Study 开放标签下塞拉德帕治疗原发性胆汁性胆管炎的长期有效性与安全性:ASSURE研究2年期的中期结果 Trivedi, PJ; Levy, C; Kowdley, KV; Gordon, SC; Bowlus, CL; Hurtado, MCL; Hirschfield, GM; Gulamhusien, AF; Lawitz, EJ; Villamil, A; Cetina, AD; Mayo, MJ; Younes, ZH; Shibolet, O; Yimam, KK; Pratt, DS; Heo, J; Morgera, U; Andreone, P; Kremer, AE; Corpechot, C; Goel, A; Peyton, A; Elbeshbeshy, H; Crittenden, DB; Heusner, C; Proehl, S; Zhou, SQ; Mcwherter, CA 分享 收藏
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Fostrox (fostroxacitabine bralpamide) plus lenvatinib in patients with locally advanced unresectable or metastatic hepatocellular carcinoma (HCC) progressed on immunotherapy combinations: Results from a multi-center phase Ib/IIa study Fostrox(fostroxacitabine bralpamide)联合仑伐替尼治疗既往接受免疫联合疗法后进展的局部晚期不可切除或转移性肝细胞癌(HCC)患者:一项多中心 Ib/IIa 期研究的结果 Chon, H.; Heo, J.; Evans, T. R. J.; Kim, D. Y.; Lim, H. Y.; Macarulla Mercade, T.; Gomez Martin, C.; Moreno Garcia, V.; Ryu, M. H.; Baumann, P.; Bhoi, S.; Jensen, M.; Tunblad, K.; Wallberg, H.; Oberg, F. G.; Reig Monzon, M. E. 分享 收藏
Efficacy and safety of bintrafusp alfa in 2 phase I expansion cohorts with advanced HCC Lim, Ho Yeong; Heo, Jeong; Peguero, Julio A.; Ryoo, Baek-Yeol; Decaens, Thomas; Barlesi, Fabrice; Moehler, Markus H.; Jehl, Genevieve; Eggleton, S. Peter; Bajars, Marcis; Gulley, James L. 分享 收藏
Switching to tenofovir alafenamide in patients with virologically suppressed chronic hepatitis B and renal or hepatic impairment: final week 96 results from an open-label, multicentre, phase 2 study 切换到替诺福韦alafenamide患者病毒学抑制慢性乙型肝炎和肾或肝损害: 最后一周96结果从开放标签,多中心,2期研究 Janssen, Harry L. A.; Lim, Young-Suk; Lampertico, Pietro; Heo, Jeong; Chen, Chi-Yi; Fournier, Claire; Tsang, Tak Yin Owen; Bae, Ho; Chen, Chien-Hung; Coffin, Carla S.; Ahn, Sang Hoon; Trinh, Huy; Flaherty, John F.; Abramov, Frida; Zhao, Yang; Liu, Yang; Lau, Audrey; German, Polina; Chuang, Wan-Long; Agarwal, Kosh; Gane, Edward 分享 收藏
Liver pharmacodynamics in an open-label phase Ib/IIa study of fostroxacitabine bralpamide (fostrox, MIV-818) in combination with lenvatinib in 2L/3L hepatocellular carcinoma Chon, H. J.; Heo, J.; Reig Monzon, M. E.; Macarulla Mercade, T.; Moreno Garcia, V.; Haugk, B.; Ness, T.; Bhoi, S.; Jensen, M.; Tunblad, K.; Wallberg, H.; Baumann, P.; Oberg, F. G. 分享 收藏
Outcomes by baseline liver function in EMERALD-1: A phase III, randomised, placebo (PBO)-controlled study of durvalumab (D) with or without bevacizumab (B) with transarterial chemoembolisation (TACE) in participants (pts) with embolisation-eligible unresectable hepatocellular carcinoma (uHCC) Chan, S. L.; Decaens, T.; Kudo, M.; Erinjeri, J. P.; Lencioni, R.; Bouattour, M.; Breder, V. V.; Heo, J.; Mazzaferro, V.; Park, J-W.; Alavez, A. Molina; Kee, K. M.; Xu, A.; Inaba, Y.; Dayyani, F.; Zotkiewicz, M.; McCoy, C. L.; Makowsky, M.; Sangro, B. 分享 收藏
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Atezolizumab plus bevacizumab versus active surveillance in patients with resected or ablated high-risk hepatocellular carcinoma (IMbrave050): a randomised, open-label, multicentre, phase 3trial 阿特珠单抗联合贝伐单抗与主动监测在切除或消融高危肝细胞癌患者中的比较 (IMbrave050): 一项随机、开放标签、多中心、3期试验 Qin, Shukui; Chen, Minshan; Cheng, Ann-Lii; Kaseb, Ahmed; Kudo, Masatoshi; Lee, Han Chu; Yopp, Adam C.; Zhou, Jian; Wang, Lu; Wen, Xiaoyu; Heo, Jeong; Tak, Won Young; Nakamura, Shinichiro; Numata, Kazushi; Uguen, Thomas; Hsiehchen, David; Cha, Edward; Hack, Stephen P.; Lian, Qinshu; Ma, Ning; Spahn, Jessica H.; Wang, Yulei; Wu, Chun; Chow, Pierce K. H. 分享 收藏