未登录 UTX coordinates TCF1 and STAT3 to control progenitor CD8+Tcell fate in autoimmune diabetes UTX协调TCF1和STAT3以控制自身免疫性糖尿病中祖细胞CD8+T细胞命运 Chen, Ho-Chung; Bang, Madison F.; Wang, Hsing-Hui; Shpargel, Karl B.; Kohn, Lisa A.; Sailer, David; Zhang, Shile; McCarthy, Ethan C.; Seyedsadr, Maryamsadat; Stevens, Satchel; Pham, Caitlyn L. H.; Zhou, Zikang; Yin, Xihui; Wilkinson, Nicole M.; Peluso, Esther M.; Bustillos, Christian; Ortega, Jessica G.; Yang, Lixin; Buzzelli, Ashlyn A.; Capati, Reina C.; Chia, Dennis J.; Mittelman, Steven D.; Reh, Christina M.; Whitmire, Jason K.; Lechner, Melissa G.; Hugo, Willy; Su, Maureen A. 分享 收藏
分享 收藏
分享 收藏
Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity Hong, Aayoung; Piva, Marco; Liu, Sixue; Hugo, Willy; Lomeli, Shirley H.; Zoete, Vincent; Randolph, Christopher E.; Yang, Zhentao; Wang, Yan; Lee, Jordan J.; Lo, Skylar J.; Sun, Lu; Vega-Crespo, Agustin; Garcia, Alejandro J.; Shackelford, David B.; Dubinett, Steven M.; Scumpia, Philip O.; Byrum, Stephanie D.; Tackett, Alan J.; Donahue, Timothy R.; Michielin, Olivier; Holmen, Sheri L.; Ribas, Antoni; Moriceau, Gatien; Lo, Roger S. 分享 收藏
Exploiting Drug Addiction Mechanisms to Select against MAPKi-Resistant Melanoma Hong, Aayoung; Moriceau, Gatien; Sun, Lu; Lomeli, Shirley; Piva, Marco; Damoiseaux, Robert; Holmen, Sheri L.; Sharpless, Norman E.; Hugo, Willy; Lo, Roger S. 分享 收藏
A pathologically expanded, clonal lineage of IL-21-producing CD4++ T cells drives inflammatory neuropathy Seyedsadr, Maryamsadat; Bang, Madison F.; Mccarthy, Ethan C.; Zhang, Shirley; Chen, Ho-Chung; Mohebbi, Mahnia; Hugo, Willy; Whitmire, Jason K.; Lechner, Melissa G.; Su, Maureen A. 分享 收藏
TLR agonists polarize interferon responses in conjunction with dendritic cell vaccination in malignant glioma: a randomized phase II Trial ( vol 15 , 3882 , 2024) Everson, Richard G.; Hugo, Willy; Sun, Lu; Antonios, Joseph; Lee, Alexander; Ding, Lizhong; Bu, Melissa; Khattab, Sara; Chavez, Carolina; Billingslea-Yoon, Emma; Salazar, Andres; Ellingson, Benjamin M.; Cloughesy, Timothy F.; Liau, Linda M.; Prins, Robert M. 分享 收藏
分享 收藏
TLR agonists polarize interferon responses in conjunction with dendritic cell vaccination in malignant glioma: a randomized phase II Trial TLR激动剂与树突状细胞疫苗接种在恶性神经胶质瘤中极化干扰素反应: 一项随机II期试验 Everson, Richard G.; Hugo, Willy; Sun, Lu; Antonios, Joseph; Lee, Alexander; Ding, Lizhong; Bu, Melissa; Khattab, Sarah; Chavez, Carolina; Billingslea-Yoon, Emma; Salazar, Andres; Ellingson, Benjamin M.; Cloughesy, Timothy F.; Liau, Linda M.; Prins, Robert M. 分享 收藏
Immune checkpoint blockade induces distinct alterations in the microenvironments of primary and metastatic brain tumors Sun, Lu; Kienzler, Jenny C.; Reynoso, Jeremy G.; Lee, Alexander; Shiuan, Eileen; Li, Shanpeng; Kim, Jiyoon; Ding, Lizhong; Monteleone, Amber J.; Owens, Geoffrey C.; Phillips, Joanna J.; Everson, Richard G.; Nathanson, David; Cloughesy, Timothy F.; Li, Gang; Liau, Linda M.; Hugo, Willy; Kim, Won; Prins, Robert M. 分享 收藏
分享 收藏
Clonally-Expanded, Thyrotoxic Autoimmune Mediator CD8+ T cells Driven by IL21 Contribute to Checkpoint Inhibitor Thyroiditis Lechner, Melissa G.; Zhou, Zikang; Scott, Lauren N.; Ortega, Jessica; Huang, Nicole; Chen, Ho-Chung; Hoang, Aline; Tafti, Rana Yakhshi; Kim, Kristy; Hugo, Willy; Famini, Pouyan; Drakaki, Alexandra; Ribas, Antoni; Angell, Trevor E.; Su, Maureen A. 分享 收藏
分享 收藏
分享 收藏
Inhibition of IL-17A Protects against Thyroid Immune-Related Adverse Events while Preserving Checkpoint Inhibitor Antitumor Efficacy br Lechner, Melissa G.; Cheng, Mandy I.; Patel, Anushi Y.; Hoang, Aline T.; Yakobian, Natalie; Astourian, Michael; Pioso, Marissa S.; Rodriguez, Eduardo D.; McCarthy, Ethan C.; Hugo, Willy; Angell, Trevor E.; Drakaki, Alexandra; Ribas, Antoni; Su, Maureen A. 分享 收藏
Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity Abt, Evan R.; Rashid, Khalid; Le, Thuc M.; Li, Suwen; Lee, Hailey R.; Lok, Vincent; Li, Luyi; Creech, Amanda L.; Labora, Amanda N.; Mandl, Hanna K.; Lam, Alex K.; Cho, Arthur; Rezek, Valerie; Wu, Nanping; Abril-Rodriguez, Gabriel; Rosser, Ethan W.; Mittelman, Steven D.; Hugo, Willy; Mehrling, Thomas; Bantia, Shanta; Ribas, Antoni; Donahue, Timothy R.; Crooks, Gay M.; Wu, Ting-Ting; Radu, Caius G. 分享 收藏
18F-FDG PET Visualizes Systemic STING Agonist-Induced Lymphocyte Activation in Preclinical Models Le, Thuc M.; Lee, Hailey R.; Abt, Evan R.; Rashid, Khalid; Creech, Amanda L.; Liang, Keke; Cui, Jing; Cho, Arthur; Wei, Liu; Labora, Amanda; Chan, Charlotte; Sanchez, Eric; Kriti, Kriti; Karin, Daniel; Li, Luyi; Wu, Nanping; Mona, Christine; Carlucci, Giuseppe; Hugo, Willy; Wu, Ting-Ting; Donahue, Timothy R.; Czernin, Johannes; Radu, Caius G. 分享 收藏
分享 收藏
分享 收藏
Pathogenic TNF-α drives peripheral nerve inflammation in an Aire-deficient model of autoimmunity Wang, Yan; Guo, Lily; Yin, Xihui; McCarthy, Ethan C.; Cheng, Mandy I.; Hoang, Aline T.; Chen, Ho-Chung; Patel, Anushi Y.; Trout, Denise Allard; Xu, Erin; Yakobian, Natalie; Hugo, Willy; Howard, James F., Jr.; Sheu, Katherine M.; Hoffmann, Alexander; Lechner, Melissa G.; Su, Maureen A. 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
