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E

Elgene Lim

St Vincent's Clinical School
H指数:53
被引数:1.6万

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荣誉奖项

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MDM2 inhibition restores p53 function to overcome dual endocrine and CDK4/6 inhibitor resistance in ER+ breast cancer

MDM2抑制通过恢复p53功能克服ER+乳腺癌对内分泌和CDK4/6抑制剂的联合耐药

Breast Cancer Research
IF5.6
2026-08-280
OA
Leila Eshraghi; Fiona H. Zhou; Sarah Alexandrou; Chan Jae Lee; Chau Lam Miu; Aliza Yong; Ashleigh Wilkinson; Denise Attwater; Man Ting Siu; Kristine Fernandez; Heloisa H. Milioli; Andrew Parker; Davendra Segara; C. Elizabeth Caldon; Neil Portman; Elgene Lim
Rb-driven transcription limits its tumour-suppressive effects in breast cancer

Rb驱动的转录限制其在乳腺癌中的肿瘤抑制作用

Nature
IF48.5
2026-08-120
OA
April C. Watt; Antonio Ahn; Catherine Blyth; Julia R. Dixon-Douglas; Krutika Ambani; Rhiannon Coulson; Michael Taylor; Keefe T. Chan; Catherine Dietrich; Brendan E. Russ; Susanne Ramm; Christabella A. Mahendra; Kun-Hui Lu; Nichelle Pires; Jesus Garcia-Sannicolas; Olivia Voulgaris; Sheena Nunag; Ching-Seng Ang; Mark A. Dawson; Elgene Lim; Monica Arnedos; Sarat Chandarlapaty; Fabrice André; Shom Goel
Endocrine therapy reprogramming of breast cancer facilitates metastatic escape via upregulation of P-Rex1/Rac1 signalling

内分泌疗法对乳腺癌的重编程通过上调P-Rex1/Rac1信号通路促进转移性逃逸

Nature Communications
IF15.7
2026-05-110
OAAI
Kristine J. Fernandez; Ghazal Sultani; Max Nobis; Brian Gloss; Leila Eshraghi; Amy E. McCart Reed; Sarah Alexandrou; Christine Lee; Daniel L. Roden; Emily I. Jones; Maryam Hasha Simad; Ewan K. A. Millar; Nenad Bartonicek; Samantha R. Oakes; Fatima Valdes-Mora; Yolanda Colino-Sanguino; Ellie T. Y. Mok; Hannah L. Williams; Jamie R. Kutasovic; Margaret C. Cummings; Janett Stoehr; Victoria Lee; Kate Harvey; Sunny Wu; Sunil R. Lakhani; Peter T. Simpson; Thomas R. Cox; Lisa M. Ooms; Christina A. Mitchell; Rob Salomon; Alexander Swarbrick; David Gallego-Ortega; Elgene Lim; Paul Timpson; C. Elizabeth Caldon
Loss of luminal lineage drives resistance to next-generation ERα antagonists in pretreated ER+ HER2− locally-advanced or metastatic breast cancer

腔内细胞系丢失驱动经治ER+ HER2−局部晚期或转移性乳腺癌对下一代ERα拮抗剂的耐药性

Nature Communications
IF15.7
2026-04-010
OAAI
Jackson Liang; Christy Ong; Kareem Heslop; Jane Guan; Vasumathi Kameswaran; Bence Daniel; Minyi Shi; Yuxin Liang; Jennifer M. Giltnane; Junko Aimi; Ching-Wei Chang; Mary R. Gates; Jennifer Eng-Wong; Pablo Perez-Moreno; Komal L. Jhaveri; Nicholas C. Turner; Elgene Lim; Ciara Metcalfe; Heather M. Moore
Imlunestrant with or without Abemaciclib in Advanced Breast Cancer: Updated Efficacy Results from the phase 3 EMBER-3 trial

Imlunestrant与或不与Abemaciclib联用治疗晚期乳腺癌：来自Ⅲ期EMBER-3试验的更新疗效结果

Annals of Oncology
IF65.4
2025-12-120
OAAI
K.L. Jhaveri; P. Neven; M.L. Casalnuovo; S-B. Kim; E. Tokunaga; P. Aftimos; C. Saura; J. O’Shaughnessy; N. Harbeck; L.A. Carey; G. Curigliano; J. Watanabe; E. Lim; J. Huang; Z. Qingyuan; A. Llombart-Cussac; C. Huang; B. Desai; Y. Limay; X.A. Wang
Diagnostic Potential of 68Ga-NeoB PET/CT with Estrogen Receptor-and Progesterone Receptor-Positive Breast Cancer Undergoing Staging or Restaging for Metastatic Disease

68Ga-NeoB PET/CT在雌激素受体和孕激素受体阳性乳腺癌患者转移性疾病分期或再分期中的诊断潜力

JOURNAL OF NUCLEAR MEDICINE
IF9.1
2025-03-270
PRE
Sabahi, Zahra; Nguyen, Andrew; Wong, Keith; Li, Sherrington; Papa, Nathan; Lim, Elgene; Dear, Rachel F.; Menzies, Alexander M.; Boyle, Frances; Antill, Yoland; Kiely, Belinda E.; Forster, Benjamin C.; Mak, Cindy; Adams, Diana; Pugliano, Lina; Spillane, Andrew; Sharma, Shikha; Hickey, Adam; Poole, Aron; Agrawal, Shikha; Khan, Sobia; Ayati, Narjess; Emmett, Louise
Induction of the TEAD Coactivator VGLL1 by Estrogen Receptor-Targeted Therapy Drives Resistance in Breast Cancer
CANCER RESEARCH
IF16.6
2024-10-020
PRE
Gemma, Carolina; Lai, Chun-Fui; Singh, Anup K.; Belfiore, Antonino; Portman, Neil; Milioli, Heloisa Z.; Periyasamy, Manikandan; Raafat, Sara; Nicholls, Alyssa J.; Davies, Claire M.; Patel, Naina R.; Simmons, Georgia M.; Fan, Hailing; Nguyen, Van T. M.; Magnani, Luca; Rakha, Emad; Martin, Lesley-Ann; Lim, Elgene; Coombes, R. Charles; Pruneri, Giancarlo; Buluwela, Laki; Ali, Simak
Imlunestrant monotherapy and in combination with abemaciclib, with or without an aromatase inhibitor, in estrogen receptor-positive (ER+), HER2-negative (HER2-) advanced breast cancer (aBC): updated results from the EMBER study
CANCER RESEARCH
IF16.6
2024-05-021
PRE
Jhaveri, Komal; Lim, Elgene; Jeselsohn, Rinath; Ma, Cynthia; Hamilton, Erika; Osborne, Cynthia; Bhave, Manali; Kaufman, Peter; Beck, J. Thaddeus; Manso, Luis; Parajuli, Ritesh; Wang, Hwei-Chung; Tao, Jessica; Dhakal, Ajay; Pierga, Jean-Yves; Lu, Yen-Shen; Larson, Tim; Gilarranz, Yolanda Jerez; Ismail-Khan, Roohi; Bacchion, Francesca; Karacsonyi, Claudia; Li, Yujia; Estrem, Shawn T.; Nguyen, Bastien; Beeram, Muralidhar
Capivasertib plus cyclindependent kinase 4/6 inhibitor and fulvestrant in hormone receptorpositive/human epidermal growth factor receptor 2-negative advanced breast cancer: updated Phase 1b analysis from CAPItello292
CANCER RESEARCH
IF16.6
2024-05-020
PRE
Hamilton, Erika; Neven, Patrick; Pistilli, Barbara; Beeram, Muralidhar; Borges, Virginia; Campone, Mario; Guimaraes, Jose Luiz Miranda; Foukakis, Theodoros; Kodahl, Annette Raskov; Lau, Peter; Lim, Elgene; Lugowska, Iwona; Rychlik, Greg; Gresty, Christopher; Miller, Claire; Sommavilla, Roberto; Sudhan, Dhivya; Rugo, Hope
Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism

肿瘤生物力学通过重新连接脂肪酸代谢改变三阴性乳腺癌的转移扩散

ADVANCED SCIENCE
IF14.1
2024-04-112
OA
Filipe, Elysse C.; Velayuthar, Sipiththa; Philp, Ashleigh; Nobis, Max; Latham, Sharissa L.; Parker, Amelia L.; Murphy, Kendelle J.; Wyllie, Kaitlin; Major, Gretel S.; Contreras, Osvaldo; Mok, Ellie T. Y.; Enriquez, Ronaldo F.; Mcgowan, Suzanne; Feher, Kristen; Quek, Lake-Ee; Hancock, Sarah E.; Yam, Michelle; Tran, Emmi; Setargew, Yordanos F. I.; Skhinas, Joanna N.; Chitty, Jessica L.; Phimmachanh, Monica; Han, Jeremy Z. R.; Cadell, Antonia L.; Papanicolaou, Michael; Mahmodi, Hadi; Kiedik, Beata; Junankar, Simon; Ross, Samuel E.; Lam, Natasha; Coulson, Rhiannon; Yang, Jessica; Zaratzian, Anaiis; Da Silva, Andrew M.; Tayao, Michael; Chin, Ian L.; Cazet, Aurelie; Kansara, Maya; Segara, Davendra; Parker, Andrew; Hoy, Andrew J.; Harvey, Richard P.; Bogdanovic, Ozren; Timpson, Paul; Croucher, David R.; Lim, Elgene; Swarbrick, Alexander; Holst, Jeff; Turner, Nigel; Choi, Yu Suk; Kabakova, Irina V.; Philp, Andrew; Cox, Thomas R.

研究方向

暂未获取到该数据
N
Neil Portman
H 指数:24论文数:73被引数:2,391
C
C. Elizabeth Caldon
H 指数:33论文数:149被引数:5,474
A
Alexander Swarbrick
H 指数:55论文数:402被引数:1.1万
W
Wayne D. Tilley
H 指数:85论文数:560被引数:2.1万
S
Sarah Alexandrou
H 指数:10论文数:37被引数:679
S
Sunny Z. Wu
H 指数:16论文数:86被引数:4,803
K
Komal Jhaveri
H 指数:42论文数:463被引数:8,781
K
Kee Ming Chia
H 指数:14论文数:48被引数:1,401
G
Geraldine Laven‐Law
H 指数:11论文数:36被引数:557
M
Mun N. Hui
H 指数:10论文数:53被引数:3,303