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S

Sarah Alexandrou

faculty of medicine unsw sydney
H指数:10
被引数:684

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荣誉奖项

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Tracking CDK1 Dynamics With a Novel Biosensor Mouse and Clinical Cohorts to Predict CDK4/6 Inhibitor Sensitivity in ER+ Breast Cancer

利用新型生物传感器小鼠和临床队列追踪CDK1动态，以预测ER+乳腺癌对CDK4/6抑制剂的敏感性

Advanced Science
IF14.1
2026-10-110
OA
Sarah Alexandrou; Kristine J. Fernandez; Min Li Huang; Ewan K. A. Millar; Claire Vennin; Leila Eshraghi; Tan Dat Timothy Lam; Victoria Lee; Nyah C. Brooks; Janett Stoehr; Cristian Guaman Mendez; Douglas Strathdee; David Stevenson; David Herrmann; Sandra O'Toole; Paul Timpson; Max Nobis; C. Elizabeth Caldon
MDM2 inhibition restores p53 function to overcome dual endocrine and CDK4/6 inhibitor resistance in ER+ breast cancer

MDM2抑制通过恢复p53功能克服ER+乳腺癌对内分泌和CDK4/6抑制剂的联合耐药

Breast Cancer Research
IF5.6
2026-08-280
OA
Leila Eshraghi; Fiona H. Zhou; Sarah Alexandrou; Chan Jae Lee; Chau Lam Miu; Aliza Yong; Ashleigh Wilkinson; Denise Attwater; Man Ting Siu; Kristine Fernandez; Heloisa H. Milioli; Andrew Parker; Davendra Segara; C. Elizabeth Caldon; Neil Portman; Elgene Lim
Endocrine therapy reprogramming of breast cancer facilitates metastatic escape via upregulation of P-Rex1/Rac1 signalling

内分泌疗法对乳腺癌的重编程通过上调P-Rex1/Rac1信号通路促进转移性逃逸

Nature Communications
IF15.7
2026-05-110
OAAI
Kristine J. Fernandez; Ghazal Sultani; Max Nobis; Brian Gloss; Leila Eshraghi; Amy E. McCart Reed; Sarah Alexandrou; Christine Lee; Daniel L. Roden; Emily I. Jones; Maryam Hasha Simad; Ewan K. A. Millar; Nenad Bartonicek; Samantha R. Oakes; Fatima Valdes-Mora; Yolanda Colino-Sanguino; Ellie T. Y. Mok; Hannah L. Williams; Jamie R. Kutasovic; Margaret C. Cummings; Janett Stoehr; Victoria Lee; Kate Harvey; Sunny Wu; Sunil R. Lakhani; Peter T. Simpson; Thomas R. Cox; Lisa M. Ooms; Christina A. Mitchell; Rob Salomon; Alexander Swarbrick; David Gallego-Ortega; Elgene Lim; Paul Timpson; C. Elizabeth Caldon
BRRIAR lncRNA alters breast cancer risk by modulating interferon signaling in cis and in trans

BRRIAR lncRNA通过调节顺式和反式干扰素信号改变乳腺癌风险

Molecular Cancer
IF33.9
2026-01-070
OAAI
Haran Sivakumaran; Sneha Nair; Mainá Bitar; Xue Lu; Lu Wang; Ji Liu; Deshapriya S. Karunarathne; P. Prakrithi; Sebastien Jacquelin; Isela Sarahi Rivera; Kristine M. Hillman; Susanne Kaufmann; Rebekah Ziegman; Wei Shi; Sarah Alexandrou; C. Elizabeth Caldon; Rakesh N. Veedu; Quan H. Nguyen; Jonathan Beesley; Michelle N. Wykes; Juliet D. French; Stacey L. Edwards
The potential of epigenetic therapy to target the 3D epigenome in endocrine-resistant breast cancer
NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2024-01-055
OAAI
Achinger-Kawecka, Joanna; Stirzaker, Clare; Portman, Neil; Campbell, Elyssa; Chia, Kee-Ming; Du, Qian; Laven-Law, Geraldine; Nair, Shalima S.; Yong, Aliza; Wilkinson, Ashleigh; Clifton, Samuel; Milioli, Heloisa H.; Alexandrou, Sarah; Caldon, C. Elizabeth; Song, Jenny; Khoury, Amanda; Meyer, Braydon; Chen, Wenhan; Pidsley, Ruth; Qu, Wenjia; Gee, Julia M. W.; Schmitt, Anthony; Wong, Emily S.; Hickey, Theresa E.; Lim, Elgene; Clark, Susan J.
The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer
NATURE MEDICINE
IF50
2021-01-18151
OA
Hickey, Theresa E.; Selth, Luke A.; Chia, Kee Ming; Laven-Law, Geraldine; Milioli, Heloisa H.; Roden, Daniel; Jindal, Shalini; Hui, Mun; Finlay-Schultz, Jessica; Ebrahimie, Esmaeil; Birrell, Stephen N.; Stelloo, Suzan; Iggo, Richard; Alexandrou, Sarah; Caldon, C. Elizabeth; Abdel-Fatah, Tarek M.; Ellis, Ian O.; Zwart, Wilbert; Palmieri, Carlo; Sartorius, Carol A.; Swarbrick, Alex; Lim, Elgene; Carroll, Jason S.; Tilley, Wayne D.
MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer

MDM2抑制联合内分泌治疗和CDK4/6抑制治疗ER阳性乳腺癌

BREAST CANCER RESEARCH
IF5.6
2020-08-1245
OAAI
Portman, Neil; Milioli, Heloisa H.; Alexandrou, Sarah; Coulson, Rhiannon; Yong, Aliza; Fernandez, Kristine J.; Chia, Kee Ming; Halilovic, Ensar; Segara, Davendra; Parker, Andrew; Haupt, Sue; Haupt, Ygal; Tilley, Wayne D.; Swarbrick, Alex; Caldon, C. Elizabeth; Lim, Elgene

研究方向

暂未获取到该数据
C
C. Elizabeth Caldon
H 指数:33论文数:149被引数:5,487
E
Elgene Lim
H 指数:53论文数:364被引数:1.6万
N
Neil Portman
H 指数:24论文数:73被引数:2,396
A
Aliza Yong
H 指数:5论文数:25被引数:175
W
Wayne D. Tilley
H 指数:85论文数:560被引数:2.1万
G
Geraldine Laven‐Law
H 指数:11论文数:36被引数:562
K
Kee Ming Chia
H 指数:14论文数:48被引数:1,406
T
Theresa E. Hickey
H 指数:46论文数:200被引数:7,753
H
Heloisa Milioli
H 指数:14论文数:58被引数:1,053
A
Ashleigh Wilkinson
H 指数:3论文数:14被引数:55