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H

Hans-Ulrich Klein

Columbia University Medical Center
H指数:50
被引数:1.2万

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Genetic correlation analysis identifies TMEM106B, ACE, and ERC2 as genetic loci shared between Alzheimer's disease and primary psychiatric disorders

遗传相关性分析确定了TMEM106B、ACE和ERC2为阿尔茨海默病与原发性精神障碍共有的遗传位点。

alzheimer's & dementia
IF0
2026-03-130
OA
Ajneesh Kumar; Nicholas R. Ray; Jiji T. Kurup; Pamela Del Rosario; Masood Manoochehri; Colin Stein; Alyssa N. De Vito; Brenna Cholerton; Robert A. Sweet; Phil L. de Jager; Hans-Ulrich Klein; Michael L. Cuccaro; Gary W. Beecham; Edward D. Huey; Christiane Reitz
A cross-disease resource of living human microglia identifies disease-enriched subsets and tool compounds recapitulating microglial states

跨疾病资源库揭示了活体人源小胶质细胞中疾病富集的亚群，以及重现小胶质细胞状态的工具化合物

Nature Neuroscience
IF20
2024-10-150
PRE
John F. Tuddenham; Mariko Taga; Verena Haage; Victoria S. Marshe; Tina Roostaei; Charles White; Annie J. Lee; Masashi Fujita; Anthony Khairallah; Ya Zhang; Gilad Green; Bradley Hyman; Matthew Frosch; Sarah Hopp; Thomas G. Beach; Geidy E. Serrano; John Corboy; Naomi Habib; Hans-Ulrich Klein; Rajesh Kumar Soni; Andrew F. Teich; Richard A. Hickman; Roy N. Alcalay; Neil Shneider; Julie Schneider; Peter A. Sims; David A. Bennett; Marta Olah; Vilas Menon; Philip L. De Jager
Cellular communities reveal trajectories of brain ageing and Alzheimer’s disease

细胞群落揭示大脑衰老和阿尔茨海默病的轨迹

Nature
IF48.5
2024-08-280
PRE
Gilad Sahar Green; Masashi Fujita; Hyun-Sik Yang; Mariko Taga; Anael Cain; Cristin McCabe; Natacha Comandante-Lou; Charles C. White; Anna K. Schmidtner; Lu Zeng; Alina Sigalov; Yangling Wang; Aviv Regev; Hans-Ulrich Klein; Vilas Menon; David A. Bennett; Naomi Habib; Philip L. De Jager
Psychosocial experiences are associated with human brain mitochondrial biology
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-06-182
OAAI
Trumpff, Caroline; Monzel, Anna S.; Sandi, Carmen; Menon, Vilas; Klein, Hans - Ulrich; Fujita, Masashi; Lee, Annie; Petyuk, Vladislav A.; Hurst, Cheyenne; Duong, Duc M.; Seyfried, Nicholas T.; Wingo, Aliza P.; Wingo, Thomas S.; Wang, Yanling; Thambisetty, Madhav; Ferrucci, Luigi; Bennett, David A.; Jager, Philip L. De; Picard, Martin
Cell subtype-specific effects of genetic variation in the Alzheimer's disease brain

阿尔茨海默氏病大脑中遗传变异的细胞亚型特异性影响

NATURE GENETICS
IF31.8
2024-03-2111
PRE
Fujita, Masashi; Gao, Zongmei; Zeng, Lu; Mccabe, Cristin; White, Charles C.; Ng, Bernard; Green, Gilad Sahar; Rozenblatt-Rosen, Orit; Phillips, Devan; Amir-Zilberstein, Liat; Lee, Hyo; Pearse, Richard V.; Khan, Atlas; Vardarajan, Badri N.; Kiryluk, Krzysztof; Ye, Chun Jimmie; Klein, Hans-Ulrich; Wang, Gao; Regev, Aviv; Habib, Naomi; Schneider, Julie A.; Wang, Yanling; Young-Pearse, Tracy; Mostafavi, Sara; Bennett, David A.; Menon, Vilas; De Jager, Philip L.
Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue
NATURE COMMUNICATIONS
IF15.7
2021-12-0213
OAAI
Ma, Yiyi; Dammer, Eric B.; Felsky, Daniel; Duong, Duc M.; Klein, Hans-Ulrich; White, Charles C.; Zhou, Maotian; Logsdon, Benjamin A.; McCabe, Cristin; Xu, Jishu; Wang, Minghui; Wingo, Thomas S.; Lah, James J.; Zhang, Bin; Schneider, Julie; Allen, Mariet; Wang, Xue; Ertekin-Taner, Nilufer; Seyfried, Nicholas T.; Levey, Allan I.; Bennett, David A.; De Jager, Philip L.
Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer's disease risk in humans

与小胶质细胞相关的表观基因组特征与apoeε4对人类阿尔茨海默病风险的减弱作用有关

ALZHEIMERS & DEMENTIA
IF11.1
2021-09-054
OA
Ma, Yiyi; Yu, Lei; Olah, Marta; Smith, Rebecca; Oatman, Stephanie R.; Allen, Mariet; Pishva, Ehsan; Zhang, Bin; Menon, Vilas; Ertekin-Taner, Nilufer; Lunnon, Katie; Bennett, David A.; Klein, Hans-Ulrich; De Jager, Philip L.

研究方向

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P
Philip L. De Jager
H 指数:147论文数:1,086被引数:10.0万
D
David A. Bennett
H 指数:197论文数:2,263被引数:18.1万
M
Martin Dugas
H 指数:74论文数:706被引数:2.1万
J
Julie A. Schneider
H 指数:149论文数:942被引数:9.9万
V
Vilas Menon
H 指数:51论文数:317被引数:1.4万
T
Torsten Haferlach
H 指数:119论文数:2,043被引数:6.1万
C
Claudia Haferlach
H 指数:83论文数:1,341被引数:3.0万
W
Wolfgang Kern
H 指数:96论文数:1,225被引数:3.6万
A
Alexander Kohlmann
H 指数:62论文数:408被引数:1.6万
S
Susanne Schnittger
H 指数:98论文数:1,255被引数:3.5万