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Detection of ESR1 Mutations in Tissue and Liquid Biopsy with Novel Next-Generation Sequencing and Digital Droplet PCR Assays: Insights from Multi-Center Real Life Data of Almost 6000 Patients 使用新型下一代测序和数字液滴PCR检测试剂盒检测组织与液体活检中的ESR1突变：来自近6000例患者多中心真实世界数据的见解 Borkar, Srushti; Markus, Fenja; Oetting, Agnes; Schmidt, Stefanie; Voessing, Christine; Horst, David; Moebs, Markus; Braicu, Elena I.; Griesinger, Frank; Horling, Katja; Tiemann, Katharina; Heukamp, Lukas C.; Willing, Eva-Maria; Vollbrecht, Claudia 分享 收藏
Targeting KDM1A in Neuroblastoma with NCL-1 Induces a Less Aggressive Phenotype and Suppresses Angiogenesis Spruessel, Annika; Suzuki, Takayoshi; Miyata, Naoki; Astrahantseff, Kathy; Szymansky, Annabell; Toedling, Joern; Thole-Kliesch, Theresa M.; Ballagee, Annika; Lodrini, Marco; Kuenkele, Annette; Truss, Matthias; Heukamp, Lukas C.; Mathia, Susanne; Hertwig, Falk; Rosenberger, Christian; Eggert, Angelika; Deubzer, Hedwig E.; Schulte, Johannes H. 分享 收藏
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Synaptopodin-2 Isoforms Have Specific Binding Partners and Display Distinct, Muscle Cell Type-Specific Expression Patterns Lohanadan, Keerthika; Assent, Marvin; Linnemann, Anja; Schuld, Julia; Heukamp, Lukas C.; Krause, Karsten; Vorgerd, Matthias; Reimann, Jens; Schaenzer, Anne; Kirfel, Gregor; Fuerst, Dieter O.; van der Ven, Peter F. M. 分享 收藏
The ADP-Ribosylation Factor 4d Restricts Regulatory T-Cell Induction via Control of IL-2 Availability ADP-核糖基化因子4d通过控制IL-2的可用性来限制调节性T细胞的诱导 Geers, Bernd; Hagenstein, Julia; Endig, Jessica; Ulrich, Hanna; Fleig, Laura; Sprezyna, Paulina; Mikulec, Julita; Heukamp, Lukas; Tiegs, Gisa; Diehl, Linda 分享 收藏
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Concordance between multiple HRD assays is substantial in high-grade ovarian cancer Weichert, W.; Bartels, S.; Baretton, G.; Braicu, E. I.; Demes, M. C.; Endris, V.; Herold, S.; Heukamp, L.; Hummel, M.; Lehmann, U.; Merkelbach-Bruse, S.; Pfarr, N.; Rad, R.; Sehouli, J.; Siemanowski, J.; Stenzinger, A.; von Schwarzenberg, K.; Vollbrecht, C.; Wild, P.; Zocholl, D. 分享 收藏
Prediction of cancer genomic instability using MALDI-imaging Kassuhn, W.; Klein, O.; Ganapathi, R.; Castillo-Tong, D. Cacsire; Horst, D.; Hummel, M.; Heukamp, L.; Weichert, W.; Vollbrecht, C.; Kulbe, H.; Sehouli, J.; Braicu, E. I. 分享 收藏
Neuroblastoma Risk Assessment and Treatment Stratification with Hybrid Capture-Based Panel Sequencing Szymansky, Annabell; Kruetzfeldt, Louisa-Marie; Heukamp, Lukas C.; Hertwig, Falk; Theissen, Jessica; Deubzer, Hedwig E.; Willing, Eva-Maria; Menon, Roopika; Fuchs, Steffen; Thole, Theresa; Schulte, Stefanie; Schmelz, Karin; Kuenkele, Annette; Lang, Peter; Fuchs, Joerg; Eggert, Angelika; Eckert, Cornelia; Fischer, Matthias; Henssen, Anton G.; Rodriguez-Fos, Elias; Schulte, Johannes H. 分享 收藏
BRAF mutations and BRAF mutation functional class have no negative impact on the clinical outcome of advanced NSCLC and associate with susceptibility to immunotherapy BRAF突变和BRAF突变功能类对晚期NSCLC的临床结局无负面影响，且与免疫治疗易感性相关 Wiesweg, Marcel; Preuss, Cedric; Roeper, Julia; Metzenmacher, Martin; Eberhardt, Wilfried; Stropiep, Ursula; Wedeken, Katrin; Reis, Henning; Herold, Thomas; Darwiche, Kaid; Aigner, Clemens; Stuschke, Martin; Schildhaus, Hans-Ulrich; Schmid, Kurt W.; Falk, Markus; Heukamp, Lukas; Tiemann, Markus; Griesinger, Frank; Schuler, Martin 分享 收藏
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Lorlatinib in pretreated ALK- or ROS1-positive lung cancer and impact of TP53 co-mutations: results from the German early access program Frost, Nikolaj; Christopoulos, Petros; Kauffmann-Guerrero, Diego; Stratmann, Jan; Riedel, Richard; Schaefer, Monica; Alt, Jurgen; Gutz, Sylvia; Christoph, Daniel C.; Laack, Eckart; Faehling, Martin; Fischer, Richard; Fenchel, Klaus; Haen, Sebastian; Heukamp, Lukas; Schulz, Christian; Griesinger, Frank 分享 收藏
ALK alterations in salivary gland carcinomas Majewska, Hanna; Gorczynski, Adam; Czapiewski, Piotr; Menon, Roopika; Mueller, Judith; Lakis, Sotirios; Heuckmann, Johannes M.; Laco, Jan; Gupta, Ruta; Andreasen, Simon; Stodulski, Dominik; Iliszko, Mariola; Dziadziuszko, Rafal; Jassem, Jacek; Heukamp, Lukas C.; Biernat, Wojciech 分享 收藏
Hybrid capture-based assays in primary diagnostics of NSCLC patients: Results from the NEOlung study Jori, B.; Gautschi, O.; Kimmich, M.; Danel, S. Beaucaire; Reinmuth, N.; Garrido Lopez, P.; Cappuzzo, F.; Forster, M.; Patel, K.; Grohe, C.; Mueller, A.; Wesseler, C.; Menon, R.; Mueller, J.; Mariotti, E.; Brinkmann, J.; Heukamp, L.; Griesinger, F. 分享 收藏
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Mutational spectrum of acquired resistance to reversible versus irreversible EGFR tyrosine kinase inhibitors Wagener-Ryczek, Svenja; Heydt, Carina; Sueptitz, Juliane; Michels, Sebastian; Falk, Markus; Alidousty, Christina; Fassunke, Jana; Ihle, Michaela Angelika; Tiemann, Markus; Heukamp, Lukas; Wolf, Juergen; Buettner, Reinhard; Merkelbach-Bruse, Sabine 分享 收藏
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